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Select item 83529641.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77376103.

Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy

Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker

EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948

PMCID:: PMC7737610

Abstract Article PDF–3.7M

Select item 76591154.

A meta-analysis of BRF2 as a prognostic biomarker in invasive breast carcinoma

Stephanie Cabarcas-Petroski, Patricio I. Meneses, Laura Schramm

BMC Cancer. 2020; 20: 1093. Published online 2020 Nov 11. doi: 10.1186/s12885-020-07569-8

PMCID:: PMC7659115

Abstract Article PDF–3.7M

Select item 74112915.

Silencing of BRF2 inhibits the growth and metastasis of lung cancer cells

Yuan Bian, Qiu Li, Qiaolian Li, Ruigen Pan

Mol Med Rep. 2020 Sep; 22(3): 1767–1774. Published online 2020 Jun 26. doi: 10.3892/mmr.2020.11285

PMCID:: PMC7411291

Abstract Article PDF–882K

Select item 69788176.

MicroRNA-425-5p Inhibits Lung Cancer Cell Growth in Vitro and in Vivo by Downregulating TFIIB-Related Factor 2

Xi Yu, Hong Zheng, Rongfei Sun, Xuejiao Qian, Ping Jiang, Bo Yang, Jiangbo Liu, Xiaoping Li

Technol Cancer Res Treat. 2020; 19: 1533033819901115. Published online 2020 Jan 22. doi: 10.1177/1533033819901115

PMCID:: PMC6978817

Abstract Article PDF–910K

Select item 60569647.

MicroRNA-373 Inhibits Cell Proliferation and Invasion via Targeting BRF2 in Human Non-small Cell Lung Cancer A549 Cell Line

Lei Wang, Junfeng Qu, Li Zhou, Fei Liao, Ju Wang

Cancer Res Treat. 2018 Jul; 50(3): 936–949. Published online 2017 Oct 12. doi: 10.4143/crt.2017.302

PMCID:: PMC6056964

Abstract Article PDF–2.8M

Select item 57918138.

New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer

Jerome Gouge, Alessandro Vannini

Transcription. 2018; 9(1): 61–66. Published online 2017 Aug 30. doi: 10.1080/21541264.2017.1335269

PMCID:: PMC5791813

Abstract Article PDF–526K

Select item 55535689.

A role for mitochondrial translation in promotion of viability in K-Ras mutant cells

Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge

Cell Rep. Author manuscript; available in PMC 2017 Aug 11.

Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 427–438. doi: 10.1016/j.celrep.2017.06.061

PMCID:: PMC5553568

Abstract Article PDF–1.8M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 552699411.

Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation

Jerome Gouge, Nicolas Guthertz, Kevin Kramm, Oleksandr Dergai, Guillermo Abascal-Palacios, Karishma Satia, Pascal Cousin, Nouria Hernandez, Dina Grohmann, Alessandro Vannini

Nat Commun. 2017; 8: 130. Published online 2017 Jul 25. doi: 10.1038/s41467-017-00126-1

PMCID:: PMC5526994

Abstract Article PDF–3.3M

Select item 467195912.

Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2

Jerome Gouge, Karishma Satia, Nicolas Guthertz, Marcella Widya, Andrew James Thompson, Pascal Cousin, Oleksandr Dergai, Nouria Hernandez, Alessandro Vannini

Cell. 2015 Dec 3; 163(6): 1375–1387. doi: 10.1016/j.cell.2015.11.005

PMCID:: PMC4671959

Abstract Article

Select item 407627113.

hnRNP F Complexes with Tristetraprolin and Stimulates ARE-mRNA Decay

Boris Reznik, Sandra L. Clement, Jens Lykke-Andersen

PLoS One. 2014; 9(6): e100992. Published online 2014 Jun 30. doi: 10.1371/journal.pone.0100992

PMCID:: PMC4076271

Abstract Article PDF–1.8M

Select item 397490914.

Placing the HIRA histone chaperone complex in the chromatin landscape

Nikolay A. Pchelintsev, Tony McBryan, Taranjit Singh Rai, John van Tuyn, Dominique Ray-Gallet, Geneviéve Almouzni, Peter D. Adams

Cell Rep. Author manuscript; available in PMC 2014 Apr 25.

Published in final edited form as: Cell Rep. 2013 Apr 25; 3(4): 1012–1019. Published online 2013 Apr 18. doi: 10.1016/j.celrep.2013.03.026

PMCID:: PMC3974909

Abstract Article PDF–1.4M

Select item 397156415.

Yu Tian, Ming Lu, Weiming Yue, Lin Li, Shuhai Li, Cun Gao, Libo Si, Lei Qi, Wensi Hu, Hui Tian

Biomed Res Int. 2014; 2014: 530786. Published online 2014 Mar 17. doi: 10.1155/2014/530786

PMCID:: PMC3971564

Abstract Article PDF–3.1M

Select item 392115316.

Ming Lu, Hui Tian, Weiming Yue, Lin Li, Shuhai Li, Lei Qi, Wensi Hu, Cun Gao, Libo Si

PLoS One. 2014; 9(2): e88032. Published online 2014 Feb 11. doi: 10.1371/journal.pone.0088032

PMCID:: PMC3921153

Abstract Article PDF–675K

Select item 377274717.

Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error

Ching-Yu Cheng, Maria Schache, M. Kamran Ikram, Terri L. Young, Jeremy A. Guggenheim, Veronique Vitart, Stuart MacGregor, Virginie J.M. Verhoeven, Veluchamy A. Barathi, Jiemin Liao, Pirro G. Hysi, Joan E. Bailey-Wilson, Beate St. Pourcain, John P. Kemp, George McMahon, Nicholas J. Timpson, David M. Evans, Grant W. Montgomery, Aniket Mishra, Ya Xing Wang, Jie Jin Wang, Elena Rochtchina, Ozren Polasek, Alan F. Wright, Najaf Amin, Elisabeth M. van Leeuwen, James F. Wilson, Craig E. Pennell, Cornelia M. van Duijn, Paulus T.V.M. de Jong, Johannes R. Vingerling, Xin Zhou, Peng Chen, Ruoying Li, Wan-Ting Tay, Yingfeng Zheng, Merwyn Chew, Consortium for Refractive Error and Myopia, Kathryn P. Burdon, Jamie E. Craig, Sudha K. Iyengar, Robert P. Igo, Jr., Jonathan H. Lass, Jr., The Fuchs’ Genetics Multi-Center Study Group, Emily Y. Chew, Toomas Haller, Evelin Mihailov, Andres Metspalu, Juho Wedenoja, Claire L. Simpson, Robert Wojciechowski, René Höhn, Alireza Mirshahi, Tanja Zeller, Norbert Pfeiffer, Karl J. Lackner, Wellcome Trust Case Control Consortium 2, Thomas Bettecken, Thomas Meitinger, Konrad Oexle, Mario Pirastu, Laura Portas, Abhishek Nag, Katie M. Williams, Ekaterina Yonova-Doing, Ronald Klein, Barbara E. Klein, S. Mohsen Hosseini, Andrew D. Paterson, The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group, Kari-Matti Makela, Terho Lehtimaki, Mika Kahonen, Olli Raitakari, Nagahisa Yoshimura, Fumihiko Matsuda, Li Jia Chen, Chi Pui Pang, Shea Ping Yip, Maurice K.H. Yap, Akira Meguro, Nobuhisa Mizuki, Hidetoshi Inoko, Paul J. Foster, Jing Hua Zhao, Eranga Vithana, E-Shyong Tai, Qiao Fan, Liang Xu, Harry Campbell, Brian Fleck, Igor Rudan, Tin Aung, Albert Hofman, André G. Uitterlinden, Goran Bencic, Chiea-Chuen Khor, Hannah Forward, Olavi Pärssinen, Paul Mitchell, Fernando Rivadeneira, Alex W. Hewitt, Cathy Williams, Ben A. Oostra, Yik-Ying Teo, Christopher J. Hammond, Dwight Stambolian, David A. Mackey, Caroline C.W. Klaver, Tien-Yin Wong, Seang-Mei Saw, Paul N. Baird

Am J Hum Genet. 2013 Aug 8; 93(2): 264–277. doi: 10.1016/j.ajhg.2013.06.016

PMCID:: PMC3772747

Abstract Article PDF–959K

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 291059919.

Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma

William W. Lockwood, Raj Chari, Bradley P. Coe, Kelsie L. Thu, Cathie Garnis, Chad A. Malloff, Jennifer Campbell, Ariane C. Williams, Dorothy Hwang, Chang-Qi Zhu, Timon P. H. Buys, John Yee, John C. English, Calum MacAulay, Ming-Sound Tsao, Adi F. Gazdar, John D. Minna, Stephen Lam, Wan L. Lam

PLoS Med. 2010 Jul; 7(7): e1000315. Published online 2010 Jul 27. doi: 10.1371/journal.pmed.1000315

PMCID:: PMC2910599

Abstract Article PDF–579K

Select item 253301320.

Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells

Stephanie Cabarcas, Joby Jacob, Ingrid Veras, Laura Schramm

BMC Mol Biol. 2008; 9: 74. Published online 2008 Aug 12. doi: 10.1186/1471-2199-9-74

PMCID:: PMC2533013

Abstract Article PDF–1.3M

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