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Select item 111157041.

Ordered transcriptional factor recruitment and epigenetic regulation of tnf-α in necrotizing acute pancreatitis

J. Sandoval, J. Pereda, J. L. Rodriguez, J. Escobar, J. Hidalgo, L. A. B. Joosten, L. Franco, J. Sastre, G. López-Rodas

Cell Mol Life Sci. 2010 May; 67(10): 1687–1697. Published online 2010 Feb 4. doi: 10.1007/s00018-010-0272-3

PMCID:: PMC11115704

Abstract Article PDF–805K

Select item 100110632.

Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX6

Zhangji Dong, Wei He, Ge Lin, Xu Chen, Sixian Cao, Tuchen Guan, Ying Sun, Yufang Zhang, Mengwei Qi, Beibei Guo, Zhihao Zhou, Run Zhuo, Ronghua Wu, Mei Liu, Yan Liu

J Biol Chem. 2023 Mar; 299(3): 103020. Published online 2023 Feb 13. doi: 10.1016/j.jbc.2023.103020

PMCID:: PMC10011063

Abstract Article PDF–6.1M

Select item 90565073.

GCN5-mediated regulation of pathological cardiac hypertrophy via activation of the TAK1-JNK/p38 signaling pathway

Jia Li, Chenghui Yan, Yilong Wang, Can Chen, Haibo Yu, Dan Liu, Kai Huang, Yaling Han

Cell Death Dis. 2022 Apr; 13(4): 421. Published online 2022 Apr 30. doi: 10.1038/s41419-022-04881-y

PMCID:: PMC9056507

Abstract Article PDF–6.7M

Select item 82083994.

GCN5 acetyltransferase inhibits PGC1α-induced hepatitis B virus biosynthesis

Xiaohui Tian, Fei Zhao, Zhikui Cheng, Ming Zhou, Xiaoguang Zhi, Jiafu Li, Kanghong Hu

Virol Sin. 2013 Aug; 28(4): 216–222. Published online 2013 Jul 2. doi: 10.1007/s12250-013-3344-3

PMCID:: PMC8208399

Abstract Article PDF–556K

Select item 63345255.

Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity

Naomi Moris, Shlomit Edri, Denis Seyres, Rashmi Kulkarni, Ana Filipa Domingues, Tina Balayo, Mattia Frontini, Cristina Pina

Stem Cells. 2018 Dec; 36(12): 1828–1838. Published online 2018 Oct 17. doi: 10.1002/stem.2919

PMCID:: PMC6334525

Abstract Article PDF–3.5M

Select item 63155456.

Kat2a and Kat2b Acetyltransferase Activity Regulates Craniofacial Cartilage and Bone Differentiation in Zebrafish and Mice

Rwik Sen, Sofia A. Pezoa, Lomeli Carpio Shull, Laura Hernandez-Lagunas, Lee A. Niswander, Kristin Bruk Artinger

J Dev Biol. 2018 Dec; 6(4): 27. Published online 2018 Nov 12. doi: 10.3390/jdb6040027

PMCID:: PMC6315545

Abstract Article PDF–2.7M

Select item 60316517.

XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1

B. Bidon, I. Iltis, M. Semer, Z. Nagy, A. Larnicol, A. Cribier, M. Benkirane, F. Coin, J-M. Egly, N. Le May

Nat Commun. 2018; 9: 2610. Published online 2018 Jul 4. doi: 10.1038/s41467-018-05010-0

PMCID:: PMC6031651

Abstract Article PDF–1.4M

Select item 58414528.

KAT2A coupled with the a-KGDH complex acts as a histone H3 succinyltransferase

Yugang Wang, Yusong R. Guo, Ke Liu, Zheng Yin, Rui Liu, Yan Xia, Lin Tan, Peiying Yang, Jong-Ho Lee, Xin-jian Li, David Hawke, Yanhua Zheng, Xu Qian, Jianxin Lyu, Jie He, Dongming Xing, Yizhi Jane Tao, Zhimin Lu

Nature. Author manuscript; available in PMC 2018 Mar 7.

Published in final edited form as: Nature. 2017 Dec 14; 552(7684): 273–277. Published online 2017 Dec 6. doi: 10.1038/nature25003

PMCID:: PMC5841452

Abstract Article PDF–3.7M

Select item 54887169.

The histone acetyltransferase GCN5 positively regulates T cell activation

Beixue Gao, Qingfei Kong, Yana Zhang, Chawon Yun, Sharon Y.R. Dent, Jianxun Song, Donna D. Zhang, Yiming Wang, Xuemei Li, Deyu Fang

J Immunol. Author manuscript; available in PMC 2018 May 15.

Published in final edited form as: J Immunol. 2017 May 15; 198(10): 3927–3938. Published online 2017 Apr 19. doi: 10.4049/jimmunol.1600312

PMCID:: PMC5488716

Abstract Article PDF–2.0M

Select item 538637310.

Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim

Yanna Wu, Shanshan Ma, Yong Xia, Yangpeng Lu, Shiyin Xiao, Yali Cao, Sidian Zhuang, Xiangpeng Tan, Qiang Fu, Longchang Xie, Zhiming Li, Zhongmin Yuan

Cell Death Dis. 2017 Jan; 8(1): e2570. Published online 2017 Jan 26. doi: 10.1038/cddis.2016.465

PMCID:: PMC5386373

Abstract Article PDF–6.3M

Select item 509558511.

KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification

Marjorie Fournier, Meritxell Orpinell, Cédric Grauffel, Elisabeth Scheer, Jean-Marie Garnier, Tao Ye, Virginie Chavant, Mathilde Joint, Fumiko Esashi, Annick Dejaegere, Pierre Gönczy, László Tora

Nat Commun. 2016; 7: 13227. Published online 2016 Oct 31. doi: 10.1038/ncomms13227

PMCID:: PMC5095585

Abstract Article PDF–2.5M

Select item 469676612.

Readout of Epigenetic Modifications

Dinshaw J. Patel, Zhanxin Wang

Annu Rev Biochem. Author manuscript; available in PMC 2015 Dec 30.

Published in final edited form as: Annu Rev Biochem. 2013; 82: 81–118. doi: 10.1146/annurev-biochem-072711-165700

PMCID:: PMC4696766

Abstract Article PDF–3.1M

Select item 419578613.

K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation

Roman M Stilling, Raik Rönicke, Eva Benito, Hendrik Urbanke, Vincenzo Capece, Susanne Burkhardt, Sanaz Bahari-Javan, Jonas Barth, Farahnaz Sananbenesi, Anna L Schütz, Jerzy Dyczkowski, Ana Martinez-Hernandez, Cemil Kerimoglu, Sharon YR Dent, Stefan Bonn, Klaus G Reymann, Andre Fischer

EMBO J. 2014 Sep 1; 33(17): 1912–1927. Published online 2014 Jul 14. doi: 10.15252/embj.201487870

PMCID:: PMC4195786

Abstract Article PDF–2.5M

Select item 406401214.

Dose- and Time-Dependent Epigenetic Changes in the Livers of Fisher 344 Rats Exposed to Furan

Aline de Conti, Tetyana Kobets, Claudia Escudero-Lourdes, Beverly Montgomery, Volodymyr Tryndyak, Frederick Alan Beland, Daniel R. Doerge, Igor Petrovych Pogribny

Toxicol Sci. 2014 Jun 1; 139(2): 371–380. Published online 2014 Mar 10. doi: 10.1093/toxsci/kfu044

PMCID:: PMC4064012

Abstract Article PDF–1.6M

Select item 406069615.

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy

Rachael M. Ivatt, Alvaro Sanchez-Martinez, Vinay K. Godena, Stephen Brown, Elena Ziviani, Alexander J. Whitworth

Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23): 8494–8499. Published online 2014 May 27. doi: 10.1073/pnas.1321207111

PMCID:: PMC4060696

Abstract Article PDF–1.5M

Select item 378453916.

Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects

Kim Ravnskjaer, Meghan F. Hogan, Denise Lackey, Laszlo Tora, Sharon Y.R. Dent, Jerrold Olefsky, Marc Montminy

J Clin Invest. 2013 Oct 1; 123(10): 4318–4328. Published online 2013 Sep 24. doi: 10.1172/JCI69035

PMCID:: PMC3784539

Abstract Article PDF–1.9M

Select item 365630517.

Lysine Acetyltransferase GCN5 Potentiates the Growth of Non-small Cell Lung Cancer via Promotion of E2F1, Cyclin D1, and Cyclin E1 Expression

Long Chen, Tingyi Wei, Xiaoxing Si, Qianqian Wang, Yan Li, Ye Leng, Anmei Deng, Jie Chen, Guiying Wang, Songcheng Zhu, Jiuhong Kang

J Biol Chem. 2013 May 17; 288(20): 14510–14521. Published online 2013 Mar 29. doi: 10.1074/jbc.M113.458737

PMCID:: PMC3656305

Abstract Article PDF–4.7M

Select item 358351718.

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach

DANIEL BÖHM, KSENIA KELLER, JULIA PIETER, NILS BOEHM, DOMINIK WOLTERS, WULF SIGGELKOW, ANTJE LEBRECHT, MARCUS SCHMIDT, HEINZ KÖLBL, NORBERT PFEIFFER, FRANZ-HERMANN GRUS

Oncol Rep. 2012 Aug; 28(2): 429–438. Published online 2012 Jun 1. doi: 10.3892/or.2012.1849