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Select item 111148381.

Migration inhibition of mammary epithelial cells by Syk is blocked in the presence of DDR1 receptors

Brit Neuhaus, Sebastian Bühren, Barbara Böck, Frauke Alves, Wolfgang F. Vogel, Friedemann Kiefer

Cell Mol Life Sci. 2011 Nov; 68(22): 3757–3770. Published online 2011 Apr 17. doi: 10.1007/s00018-011-0676-8

PMCID:: PMC11114838

Abstract Article PDF–2.2M

Select item 76564572.

Fate and functional roles of Prominin 1⁺ cells in liver injury and cancer

Raymond Wu, Stephanie Pan, Yibu Chen, Yasuhiro Nakano, Meng Li, Steven Balog, Hidekazu Tsukamoto

Sci Rep. 2020; 10: 19412. Published online 2020 Nov 10. doi: 10.1038/s41598-020-76458-8

PMCID:: PMC7656457

Abstract Article PDF–3.8M

Select item 75915793.

Silencing of sinusoidal DDR1 reduces murine liver metastasis by colon carcinoma

Irene Romayor, Iker Badiola, Aitor Benedicto, Joana Márquez, Alba Herrero, Beatriz Arteta, Elvira Olaso

Sci Rep. 2020; 10: 18398. Published online 2020 Oct 27. doi: 10.1038/s41598-020-75395-w

PMCID:: PMC7591579

Abstract Article PDF–4.4M

Select item 72428764.

Discoidin domain receptor 1-deletion ameliorates fibrosis and promotes adipose tissue beiging, brown fat activity, and increased metabolic rate in a mouse model of cardiometabolic disease

Marsel Lino, David Ngai, Alison Liu, Amanda Mohabeer, Cameron Harper, Laura-lee Caruso, Stephanie A. Schroer, Fred Fu, Trevor McKee, Adria Giacca, Minna Woo, Michelle P. Bendeck

Mol Metab. 2020 Sep; 39: 101006. Published online 2020 Apr 28. doi: 10.1016/j.molmet.2020.101006

PMCID:: PMC7242876

Abstract Article PDF–3.9M

Select item 69859365.

2-Amino-2,3-dihydro-1H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy

Dongsheng Zhu, Huocong Huang, Daniel M. Pinkas, Jinfeng Luo, Debolina Ganguly, Alice E. Fox, Emily Arner, Qiuping Xiang, Zheng-Chao Tu, Alex N. Bullock, Rolf A. Brekken, Ke Ding, Xiaoyun Lu

J Med Chem. 2019 Aug 22; 62(16): 7431–7444. Published online 2019 Jul 16. doi: 10.1021/acs.jmedchem.9b00365

PMCID:: PMC6985936

Abstract Article PDF–4.2M

Select item 67272696.

The Extracellular Matrix Receptor Discoidin Domain Receptor 1 Regulates Collagen Transcription by Translocating to the Nucleus

Manuel Chiusa, Wen Hu, Hong-Jun Liao, Yan Su, Corina M. Borza, Mark P. de Caestecker, Nataliya I. Skrypnyk, Agnes B. Fogo, Vadim Pedchenko, Xiyue Li, Ming-Zhi Zhang, Billy G. Hudson, Trayambak Basak, Roberto M. Vanacore, Roy Zent, Ambra Pozzi

J Am Soc Nephrol. 2019 Sep; 30(9): 1605–1624. Published online 2019 Aug 5. doi: 10.1681/ASN.2018111160

PMCID:: PMC6727269

Abstract Article

Select item 65992387.

MicroRNA-486-3p functions as a tumor suppressor in oral cancer by targeting DDR1

Sung-Tau Chou, Hsuan-Yu Peng, Kuan-Chi Mo, Yuan-Ming Hsu, Guan-Hsun Wu, Jenn-Ren Hsiao, Su-Fang Lin, Horng-Dar Wang, Shine-Gwo Shiah

J Exp Clin Cancer Res. 2019; 38: 281. Published online 2019 Jun 28. doi: 10.1186/s13046-019-1283-z

PMCID:: PMC6599238

Abstract Article PDF–3.0M

Select item 65426478.

Altered Expression of DDR1 in Clear Cell Renal Cell Carcinoma Correlates With miR-199a/b-5p and Patients’ Outcome

E. BARTLOMIEJ KRAZINSKI, JOLANTA KIEWISZ, AGNIESZKA SLIWINSKA-JEWSIEWICKA, E. ANNA KOWALCZYK, JEDRZEJ GRZEGRZOLKA, JANUSZ GODLEWSKI, PRZEMYSLAW KWIATKOWSKI, PIOTR DZIEGIEL, ZBIGNIEW KMIEC

Cancer Genomics Proteomics. 2019 May-Jun; 16(3): 179–193. Published online 2019 May 3. doi: 10.21873/cgp.20124

PMCID:: PMC6542647

Abstract Article PDF–665K

Select item 58875469.

Inhibition of DDR1‐BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer

Maya Jeitany, Cédric Leroy, Priscillia Tosti, Marie Lafitte, Jordy Le Guet, Valérie Simon, Debora Bonenfant, Bruno Robert, Fanny Grillet, Caroline Mollevi, Safia El Messaoudi, Amaëlle Otandault, Lucile Canterel‐Thouennon, Muriel Busson, Alain R Thierry, Pierre Martineau, Julie Pannequin, Serge Roche, Audrey Sirvent

EMBO Mol Med. 2018 Apr; 10(4): e7918. Published online 2018 Feb 9. doi: 10.15252/emmm.201707918

PMCID:: PMC5887546

Abstract Article PDF–1.6M

Select item 585996610.

Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers

Ken Takai, Allison P. Drain, Devon A. Lawson, Laurie E. Littlepage, Marcela Karpuj, Kai Kessenbrock, Annie Le, Kenichi Inoue, Valerie M. Weaver, Zena Werb

Genes Dev. 2018 Feb 1; 32(3-4): 244–257. doi: 10.1101/gad.301366.117

PMCID:: PMC5859966

Abstract Article PDF–21M

Select item 582745511.

Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice

Xiujie Sun, Kshama Gupta, Bogang Wu, Deyi Zhang, Bin Yuan, Xiaowen Zhang, Huai-Chin Chiang, Chi Zhang, Tyler J. Curiel, Michelle P. Bendeck, Stephen Hursting, Yanfen Hu, Rong Li

J Biol Chem. 2018 Feb 23; 293(8): 2841–2849. Published online 2018 Jan 3. doi: 10.1074/jbc.RA117.000672

PMCID:: PMC5827455

Abstract Article PDF–1.6M

Select item 567302212.

E2F1 silencing inhibits migration and invasion of osteosarcoma cells via regulating DDR1 expression

Zhaofeng Wang, Xianjie Sun, Yi Bao, Juanfen Mo, Hengchao Du, Jichao Hu, Xingen Zhang

Int J Oncol. 2017 Dec; 51(6): 1639–1650. Published online 2017 Oct 16. doi: 10.3892/ijo.2017.4165

PMCID:: PMC5673022

Abstract Article PDF–1.8M

Select item 552623313.

Suppressing miR-199a-3p by promoter methylation contributes to tumor aggressiveness and cisplatin resistance of ovarian cancer through promoting DDR1 expression

Yuao Deng, Fang Zhao, Liu Hui, Xiuyun Li, Danyu Zhang, Wang Lin, Zhiqiang Chen, Yingxia Ning

J Ovarian Res. 2017; 10: 50. Published online 2017 Jul 25. doi: 10.1186/s13048-017-0333-4

PMCID:: PMC5526233

Abstract Article PDF–5.2M

Select item 479436414.

Anticancer Effects of Mesothelin-targeted Immunotoxin Therapy are Regulated by Tyrosine Kinase DDR1

Fatima Ali-Rahmani, David J. FitzGerald, Scott Martin, Paresma Patel, Marco Prunotto, Pinar Ormanoglu, Craig Thomas, Ira Pastan

Cancer Res. Author manuscript; available in PMC 2017 Mar 15.

Published in final edited form as: Cancer Res. 2016 Mar 15; 76(6): 1560–1568. Published online 2015 Dec 30. doi: 10.1158/0008-5472.CAN-15-2401

PMCID:: PMC4794364

Abstract Article PDF–1.7M

Select item 456585215.

The Regulation of Matrix Metalloproteinase Expression and the Role of Discoidin Domain Receptor 1/2 Signalling in Zoledronate-treated PC3 Cells

Buket Reel, Ceren Gonen Korkmaz, Mehmet Zuhuri Arun, Gokce Yildirim, Deniz Ogut, Aysegul Kaymak, Serap Cilaker Micili, Bekir Ugur Ergur

J Cancer. 2015; 6(10): 1020–1029. Published online 2015 Aug 28. doi: 10.7150/jca.12733

PMCID:: PMC4565852

Abstract Article PDF–1.1M

Select item 454754416.

Effect of Hypoxia on DDR1 Expression in Pituitary Adenomas

Shouchun Li, Zhiwen Zhang, Jinghui Xue, Xiaoming Guo, Shuli Liang, Aijun Liu

Med Sci Monit. 2015; 21: 2433–2438. Published online 2015 Aug 19. doi: 10.12659/MSM.894205

PMCID:: PMC4547544

Abstract Article PDF–691K

Select item 405874717.

Structural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase Inhibitors

Peter Canning, Li Tan, Kiki Chu, Sam W. Lee, Nathanael S. Gray, Alex N. Bullock

J Mol Biol. 2014 Jun 26; 426(13): 2457–2470. doi: 10.1016/j.jmb.2014.04.014

PMCID:: PMC4058747

Abstract Article PDF–3.0M

Select item 380049618.

Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

Hyung-Gu Kim, Li Tan, Ellen L. Weisberg, Feiyang Liu, Peter Canning, Hwan Geun Choi, Scott A. Ezell, Hong Wu, Zheng Zhao, Jinhua Wang, Anna Mandinova, James D. Griffin, Alex N. Bullock, Qingsong Liu, Sam W. Lee, Nathanael S. Gray

ACS Chem Biol. 2013 Oct 18; 8(10): 2145–2150. Published online 2013 Jul 30. doi: 10.1021/cb400430t

Correction in:: ACS Chem Biol. 2014 Mar 21; 9(3): 840.

PMCID:: PMC3800496

Abstract Article PDF–5.8M

Select item 363381919.

Novel role of sorting nexin 5 in renal D₁ dopamine receptor trafficking and function: implications for hypertension

Van Anthony M. Villar, Ines Armando, Hironobu Sanada, Lauren C. Frazer, Christen M. Russo, Patricia M. Notario, Hewang Lee, Lauren Comisky, Holly Ann Russell, Yu Yang, Julie A. Jurgens, Pedro A. Jose, John E. Jones

FASEB J. 2013 May; 27(5): 1808–1819. doi: 10.1096/fj.12-208439

PMCID:: PMC3633819

Abstract Article

Select item 358195420.

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins

Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110