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Select item 106761311.

TXNIP activates NLRP3/IL-1β and participate in inflammatory response and oxidative stress to promote deep venous thrombosis

Jianwen Fei, Haixia Wang, Jin Han, Xuefeng Zhang, Hongfu Ma, Xiao Qin, Chaoxiao Yu, Junjie Jiang

Exp Biol Med (Maywood) 2023 Sep; 248(18): 1588–1597. Published online 2023 Sep 25. doi: 10.1177/15353702231191124

PMCID:: PMC10676131

Abstract Article PDF–15M

Select item 105614542.

Ubiquitin-specific peptidase 25 exacerbated osteoarthritis progression through facilitating TXNIP ubiquitination and NLRP3 inflammasome activation

Jie Sui, Fei Dai, Jiusheng Shi, Changcheng Zhou

J Orthop Surg Res. 2023; 18: 762. Published online 2023 Oct 9. doi: 10.1186/s13018-023-04083-y

PMCID:: PMC10561454

Abstract Article PDF–6.3M

Select item 104353613.

SRY-box transcription factor 9 modulates Müller cell gliosis in diabetic retinopathy by upregulating TXNIP transcription

Sheng Li, Gaoxiang Ouyang, Linhui Yuan, Xiaoxuan Wu, Lijun Zhang

Exp Anim. 2023; 72(3): 302–313. Published online 2023 Jan 16. doi: 10.1538/expanim.22-0126

PMCID:: PMC10435361

Abstract Article PDF–3.0M

Select item 90957114.

Energy restriction induced SIRT6 inhibits microglia activation and promotes angiogenesis in cerebral ischemia via transcriptional inhibition of TXNIP

Ming-Yu Song, Fang Yi, Hui Xiao, Jun Yin, Qing Huang, Jian Xia, Xiao-Meng Yin, Yan-Bin Wen, Le Zhang, Yun-Hai Liu, Bo Xiao, Wen-Ping Gu

Cell Death Dis. 2022 May; 13(5): 449. Published online 2022 May 11. doi: 10.1038/s41419-022-04866-x

PMCID:: PMC9095711

Abstract Article PDF–6.0M

Select item 88068785.

Circular RNA SMEK1 promotes neuropathic pain in rats through targeting microRNA-216a-5p to mediate Thioredoxin Interacting Protein (TXNIP) expression

Yufu Xin, Xinrong Song, Qingye Ge

Bioengineered. 2021; 12(1): 5540–5551. Published online 2021 Sep 14. doi: 10.1080/21655979.2021.1965811

PMCID:: PMC8806878

Abstract Article PDF–2.1M

Select item 82575416.

Long Non-coding RNA GAS5 Worsens Coronary Atherosclerosis Through MicroRNA-194-3p/TXNIP Axis

Yanbing Li, Yu Geng, Boda Zhou, Xuejiao Wu, Ou Zhang, Xiaonan Guan, Yajun Xue, Siyuan Li, Xianjing Zhuang, Jie Zhou, Meng Chang, Guobin Miao, Lizhong Wang

Mol Neurobiol. 2021; 58(7): 3198–3207. Published online 2021 Feb 27. doi: 10.1007/s12035-021-02332-x

PMCID:: PMC8257541

Abstract Article PDF–874K

Select item 82223537.

TXNIP, a novel key factor to cause Schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression

Xiang Zhang, Song Zhao, Qingqing Yuan, Lin Zhu, Fan Li, Hui Wang, Dezhi Kong, Jun Hao

Cell Death Dis. 2021 Jul; 12(7): 642. Published online 2021 Jun 23. doi: 10.1038/s41419-021-03930-2

PMCID:: PMC8222353

Abstract Article PDF–5.1M

Select item 72616538.

Acute bout of exercise downregulates thioredoxin‐interacting protein expression in rat contracting skeletal muscles

Song‐Gyu Ra, Emi Kawamoto, Keiichi Koshinaka, Maiko Iwabe, Yuki Tomiga, Hiroki Iizawa, Hiroki Honda, Yasuki Higaki, Kentaro Kawanaka

Physiol Rep. 2020 Jun; 8(11): e14388. Published online 2020 May 31. doi: 10.14814/phy2.14388

PMCID:: PMC7261653

Abstract Article PDF–758K

Select item 69647219.

Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats

Jing Yu, Wen-na Wang, Nathanael Matei, Xue Li, Jin-wei Pang, Jun Mo, Sheng-pan Chen, Ji-ping Tang, Min Yan, John H. Zhang

Oxid Med Cell Longev. 2020; 2020: 4717258. Published online 2020 Jan 3. doi: 10.1155/2020/4717258

PMCID:: PMC6964721

Abstract Article PDF–3.5M

Select item 692335110.

Gal-3 is a potential biomarker for spinal cord injury and Gal-3 deficiency attenuates neuroinflammation through ROS/TXNIP/NLRP3 signaling pathway

Zhouliang Ren, Weidong Liang, Jun Sheng, Chuanhui Xun, Tao Xu, Rui Cao, Weibin Sheng

Biosci Rep. 2019 Dec 20; 39(12): BSR20192368. Published online 2019 Dec 16. doi: 10.1042/BSR20192368

PMCID:: PMC6923351

Abstract Article PDF–2.5M

Select item 681174811.

Ketamine induces endoplasmic reticulum stress in rats and SV-HUC-1 human uroepithelial cells by activating NLRP3/TXNIP aix

Lingjuan Cui, Xiaoyan Jiang, Chengjun Zhang, Danxia Li, Shengqiang Yu, Fengchun Wan, Yue Ma, Wei Guo, Zhengfei Shan

Biosci Rep. 2019 Oct 30; 39(10): BSR20190595. Published online 2019 Oct 18. doi: 10.1042/BSR20190595

PMCID:: PMC6811748

Abstract Article PDF–1.5M

Select item 677040912.

FMK, an Inhibitor of p90RSK, Inhibits High Glucose-Induced TXNIP Expression via Regulation of ChREBP in Pancreatic β Cells

Jung-Hwa Han, Suji Kim, Sujin Kim, Heejung Lee, So-Young Park, Chang-Hoon Woo

Int J Mol Sci. 2019 Sep; 20(18): 4424. Published online 2019 Sep 9. doi: 10.3390/ijms20184424

PMCID:: PMC6770409

Abstract Article PDF–2.6M

Select item 660564113.

Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction

Chun Yang, Wan Xia, Xiaolin Liu, Jian Lin, Aiping Wu

Int J Mol Med. 2019 Aug; 44(2): 417–426. Published online 2019 Jun 6. doi: 10.3892/ijmm.2019.4232

PMCID:: PMC6605641

Abstract Article PDF–1.2M

Select item 648995814.

Acupuncture inhibits TXNIP‐associated oxidative stress and inflammation to attenuate cognitive impairment in vascular dementia rats

Si‐Qi Du, Xue‐Rui Wang, Wen Zhu, Yang Ye, Jing‐Wen Yang, Si‐Ming Ma, Cai‐Shuo Ji, Cun‐Zhi Liu

CNS Neurosci Ther. 2018 Jan; 24(1): 39–46. Published online 2017 Nov 6. doi: 10.1111/cns.12773

PMCID:: PMC6489958

Abstract Article PDF–1.0M

Select item 648816915.

Role of the thioredoxin interacting protein in diabetic nephropathy and the mechanism of regulating NOD-like receptor protein 3 inflammatory corpuscle

Chunmei Gu, Shumei Liu, Hongyue Wang, Haichuan Dou

Int J Mol Med. 2019 Jun; 43(6): 2440–2450. Published online 2019 Apr 11. doi: 10.3892/ijmm.2019.4163

PMCID:: PMC6488169

Abstract Article PDF–970K

Select item 565800616.

Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: Implications for diabetic retinopathy

Takhellambam S. Devi, Ken-Ichi Hosoya, Tetsuya Terasaki, Lalit P. Singh

Exp Cell Res. Author manuscript; available in PMC 2017 Oct 26.

Published in final edited form as: Exp Cell Res. 2013 Apr 15; 319(7): 1001–1012. Published online 2013 Jan 24. doi: 10.1016/j.yexcr.2013.01.012

PMCID:: PMC5658006

Abstract Article PDF–1.4M

Select item 552071117.

TXNIP regulates mitophagy in retinal Müller cells under high-glucose conditions: implications for diabetic retinopathy

Takhellambam Swornalata Devi, Mallika Somayajulu, Renu Anjan Kowluru, Lalit Pukhrambam Singh

Cell Death Dis. 2017 May; 8(5): e2777. Published online 2017 May 11. doi: 10.1038/cddis.2017.190

PMCID:: PMC5520711

Abstract Article PDF–6.8M

Select item 542606918.

Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage

Qing Zhao, Xudong Che, Hongxia Zhang, Pianpian Fan, Guanping Tan, Liu Liu, Dengzhi Jiang, Jun Zhao, Xiang Xiang, Yidan Liang, Xiaochuan Sun, Zhaohui He

J Neuroinflammation. 2017; 14: 104. Published online 2017 May 11. doi: 10.1186/s12974-017-0878-6

PMCID:: PMC5426069

Abstract Article PDF–3.1M

Select item 541243819.

Thioredoxin-Interacting Protein Mediates Apoptosis in Early Brain Injury after Subarachnoid Haemorrhage

Qing Zhao, Xudong Che, Hongxia Zhang, Guanping Tan, Liu Liu, Dengzhi Jiang, Jun Zhao, Xiang Xiang, Xiaochuan Sun, Zhaohui He

Int J Mol Sci. 2017 Apr; 18(4): 854. Published online 2017 Apr 18. doi: 10.3390/ijms18040854

PMCID:: PMC5412438

Abstract Article PDF–5.7M

Select item 493392820.

Thioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathway

Chunling Huang, Yuan Zhang, Darren J. Kelly, Christina Y. R. Tan, Anthony Gill, Delfine Cheng, Filip Braet, Jin-Sung Park, Carolyn M. Sue, Carol A. Pollock, Xin-Ming Chen

Sci Rep. 2016; 6: 29196. Published online 2016 Jul 6. doi: 10.1038/srep29196