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Items: 1 to 20 of 159

1.
The faah gene is the first direct target of estrogen in the testis: role of histone demethylase LSD1
Paola Grimaldi, Mariangela Pucci, Sara Di Siena, Daniele Di Giacomo, Valentina Pirazzi, Raffaele Geremia, Mauro Maccarrone
Cell Mol Life Sci. 2012 Dec; 69(24): 4177–4190. Published online 2012 Jul 17. doi: 10.1007/s00018-012-1074-6
PMCID:
PMC11114663
AbstractArticlePDF–780K
2.
LSD1 drives intestinal epithelial maturation and controls small intestinal immune cell composition independent of microbiota in a murine model
Alberto Díez-Sánchez, Håvard T. Lindholm, Pia M. Vornewald, Jenny Ostrop, Rouan Yao, Andrew B. Single, Anne Marstad, Naveen Parmar, Tovah N. Shaw, Mara Martín-Alonso, Menno J. Oudhoff
Nat Commun. 2024; 15: 3412. Published online 2024 Apr 22. doi: 10.1038/s41467-024-47815-2
PMCID:
PMC11035651
AbstractArticlePDF–9.3M
3.
Kdm1a safeguards the topological boundaries of PRC2-repressed genes and prevents aging-related euchromatinization in neurons
Beatriz del Blanco, Sergio Niñerola, Ana M. Martín-González, Juan Paraíso-Luna, Minji Kim, Rafael Muñoz-Viana, Carina Racovac, Jose V. Sanchez-Mut, Yijun Ruan, Ángel Barco
Nat Commun. 2024; 15: 1781. Published online 2024 Mar 7. doi: 10.1038/s41467-024-45773-3
PMCID:
PMC10920760
AbstractArticlePDF–8.9M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Histone demethylase KDM1A promotes hepatic steatosis and inflammation by increasing chromatin accessibility in NAFLD
Zifeng Yang, Siyao Zhang, Xiang Liu, Rui Shu, Wei Shi, Weiyi Qu, Dianyu Liu, Zhiwei Cai, Ye Wang, Xu Cheng, Yemao Liu, Xiao-Jing Zhang, Lan Bai, Hongliang Li, Zhi-Gang She
J Lipid Res. 2024 Mar; 65(3): 100513. Published online 2024 Jan 29. doi: 10.1016/j.jlr.2024.100513
PMCID:
PMC10907224
AbstractArticlePDF–6.7M
6.
A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis
Pengfei Guo, Rebecca C Lim, Keshari Rajawasam, Tiffany Trinh, Hong Sun, Hui Zhang
eLife. 2024; 13: e86168. Published online 2024 Feb 12. doi: 10.7554/eLife.86168
PMCID:
PMC10901513
AbstractArticlePDF–9.2M
7.
Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development
Huahua Liu, Rui Zhou, Shanshan Li, Jinling Dong, Yuan Fang, Yuru Luo, Hongyu Su, Baochang Lai, Lingli Liang, Donghong Zhang, Yanmin Zhang, John Y-J. Shyy, Bin Zhou, Zuyi Yuan, Yidong Wang
iScience. 2024 Jan 19; 27(1): 108722. Published online 2023 Dec 13. doi: 10.1016/j.isci.2023.108722
PMCID:
PMC10788269
AbstractArticlePDF–11M
8.
Lsd1 safeguards T-cell development via suppressing endogenous retroelements and interferon responses
Miaoran Xia, Bingbing Wang, Wujianan Sun, Dengyu Ji, Hang Zhou, Xuefeng Huang, Minghang Yu, Ziyang Su, Ping Chen, Kun Qu, Xi Wang
Life Sci Alliance. 2023 Oct; 6(10): e202302042. Published online 2023 Jul 10. doi: 10.26508/lsa.202302042
PMCID:
PMC10345215
AbstractArticlePDF–4.6M
9.
Lnc_000048 Promotes Histone H3K4 Methylation of MAP2K2 to Reduce Plaque Stability by Recruiting KDM1A in Carotid Atherosclerosis
Shuai Zhang, Yu Sun, Qi Xiao, Mengying Niu, Xudong Pan, Xiaoyan Zhu
Mol Neurobiol. 2023; 60(5): 2572–2586. Published online 2023 Jan 23. doi: 10.1007/s12035-023-03214-0
PMCID:
PMC10039837
AbstractArticlePDF–2.7M
10.
Crucial Role of Lysine-Specific Histone Demethylase 1 in RANKL-Mediated Osteoclast Differentiation
Mina Ding, Zhihao Chen, Eunjin Cho, Sang-Wook Park, Tae-Hoon Lee
Int J Mol Sci. 2023 Feb; 24(4): 3605. Published online 2023 Feb 10. doi: 10.3390/ijms24043605
PMCID:
PMC9967819
AbstractArticlePDF–6.7M
11.
Deletion of histone demethylase Lsd1 (Kdm1a) during retinal development leads to defects in retinal function and structure
Salma Ferdous, Debresha A. Shelton, Tatiana E. Getz, Micah A. Chrenek, Nancy L’Hernault, Jana T. Sellers, Vivian R. Summers, P. Michael Iuvone, Jeremy M. Boss, Jeffrey H. Boatright, John M. Nickerson
Front Cell Neurosci. 2023; 17: 1104592. Published online 2023 Feb 10. doi: 10.3389/fncel.2023.1104592
PMCID:
PMC9950115
AbstractArticlePDF–11M
12.
Antagonistic action of GPS2 and KDM1A at enhancers governs alternative macrophage activation by interleukin 4
Zhiqiang Huang, Astradeni Efthymiadou, Ning Liang, Rongrong Fan, Eckardt Treuter
Nucleic Acids Res. 2023 Feb 22; 51(3): 1067–1086. Published online 2023 Jan 5. doi: 10.1093/nar/gkac1230
PMCID:
PMC9943668
AbstractArticlePDF–7.8M
13.
LSD1 defines the fiber type-selective responsiveness to environmental stress in skeletal muscle
Hirotaka Araki, Shinjiro Hino, Kotaro Anan, Kanji Kuribayashi, Kan Etoh, Daiki Seko, Ryuta Takase, Kensaku Kohrogi, Yuko Hino, Yusuke Ono, Eiichi Araki, Mitsuyoshi Nakao
eLife. 2023; 12: e84618. Published online 2023 Jan 25. doi: 10.7554/eLife.84618
PMCID:
PMC9876571
AbstractArticlePDF–5.1M
14.
A NR2E1‐interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells
Rong Hu, Umar Farook Shahul Hameed, Xiang Sun, Balakrishnan Shenbaga Moorthy, Wen Zhang, Philip D. Jeffrey, Li Zhou, Xin Ma, Fangjin Chen, Jianfeng Pei, Pankaj K. Giri, Yonggao Mou, Kunchithapadam Swaminathan, Ping Yuan
Cell Prolif. 2023 Jan; 56(1): e13350. Published online 2022 Nov 2. doi: 10.1111/cpr.13350
PMCID:
PMC9816925
AbstractArticlePDF–4.3M
15.
Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity
Bastian Ramms, Dennis P. Pollow, Han Zhu, Chelsea Nora, Austin R. Harrington, Ibrahim Omar, Philip L.S.M. Gordts, Matthew Wortham, Maike Sander
Diabetes. 2022 Dec; 71(12): 2513–2529. Published online 2022 Sep 28. doi: 10.2337/db21-1131
PMCID:
PMC9750949
AbstractArticlePDF–35M
16.
CircRNA AFF4 induced by KDM1A promotes osteogenic differentiation through FNDC5/Irisin pathway
Ansong Liu, Yong Chen, Da Zhong, Chenggong Wang, Mi Yu, Chao Liu, Zhijun Yang, Wenkang Chen, Ke Yin
Mol Med. 2022; 28: 134. Published online 2022 Nov 18. doi: 10.1186/s10020-022-00557-7
PMCID:
PMC9673395
AbstractArticlePDF–12M
17.
Mechanism of LSD1 in oxygen-glucose deprivation/reoxygenation-induced pyroptosis of retinal ganglion cells via the miR-21-5p/NLRP12 axis
Xiuling Yu, Tongtong Niu, Chi Liu
BMC Neurosci. 2022; 23: 63. Published online 2022 Nov 10. doi: 10.1186/s12868-022-00747-3
PMCID:
PMC9650888
AbstractArticlePDF–2.2M
18.
The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis
Pengfei Guo, Nam Hoang, Joseph Sanchez, Elaine H. Zhang, Keshari Rajawasam, Kristiana Trinidad, Hong Sun, Hui Zhang
Nat Commun. 2022; 13: 6696. Published online 2022 Nov 5. doi: 10.1038/s41467-022-34348-9
PMCID:
PMC9637158
AbstractArticlePDF–3.3M
19.
Lysine‐specific demethylase 1 aggravated oxidative stress and ferroptosis induced by renal ischemia and reperfusion injury through activation of TLR4/NOX4 pathway in mice
Ruikang Feng, Yufeng Xiong, Yourong Lei, Qin Huang, Hao Liu, Xiaojie Zhao, Zhiyuan Chen, Hui Chen, Xiuheng Liu, Lei Wang, Xiaodong Weng
J Cell Mol Med. 2022 Aug; 26(15): 4254–4267. Published online 2022 Jun 30. doi: 10.1111/jcmm.17444
PMCID:
PMC9344828
AbstractArticlePDF–17M
20.
Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism
Veronica Astro, Gustavo Ramirez-Calderon, Roberta Pennucci, Jonatan Caroli, Alfonso Saera-Vila, Kelly Cardona-Londoño, Chiara Forastieri, Elisabetta Fiacco, Fatima Maksoud, Maryam Alowaysi, Elisa Sogne, Andrea Falqui, Federico Gonzàlez, Nuria Montserrat, Elena Battaglioli, Andrea Mattevi, Antonio Adamo
iScience. 2022 Jul 15; 25(7): 104665. Published online 2022 Jun 23. doi: 10.1016/j.isci.2022.104665
PMCID:
PMC9287196
AbstractArticlePDF–7.7M

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