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Select item 75306571.

A study of associations between CUBN, HNF1A, and LIPC gene polymorphisms and coronary artery disease

Han Sung Park, In Jai Kim, Eun Gyo Kim, Chang Soo Ryu, Jeong Yong Lee, Eun Ju Ko, Hyeon Woo Park, Jung Hoon Sung, Nam Keun Kim

Sci Rep. 2020; 10: 16294. Published online 2020 Oct 1. doi: 10.1038/s41598-020-73048-6

PMCID:: PMC7530657

Abstract Article PDF–1.1M

Select item 72167252.

Beneficial impact of epigallocatechingallate on LDL-C through PCSK9/LDLR pathway by blocking HNF1α and activating FoxO3a

Chuan-Jue Cui, Jing-Lu Jin, Lin-Na Guo, Jing Sun, Na-Qiong Wu, Yuan-Lin Guo, Geng Liu, Qian Dong, Jian-Jun Li

J Transl Med. 2020; 18: 195. Published online 2020 May 12. doi: 10.1186/s12967-020-02362-4

PMCID:: PMC7216725

Abstract Article PDF–4.1M

Select item 66811393.

Association of the HNF1A polymorphisms and serum lipid traits, the risk of coronary artery disease and ischemic stroke

Yi‐Jiang Zhou, Rui‐Xing Yin, Shao‐Cai Hong, Qian Yang, Xiao‐Li Cao, Wu‐Xian Chen

J Gene Med. 2017 Jan-Feb; 19(1-2): e2941. Published online 2017 Feb 1. doi: 10.1002/jgm.2941

PMCID:: PMC6681139

Abstract Article PDF–201K

Select item 62760944.

Small Heterodimer Partner Regulates Circadian Cytochromes p450 and Drug-Induced Hepatotoxicity

Tianpeng Zhang, Fangjun Yu, Lianxia Guo, Min Chen, Xue Yuan, Baojian Wu

Theranostics. 2018; 8(19): 5246–5258. Published online 2018 Oct 22. doi: 10.7150/thno.28676

PMCID:: PMC6276094

Abstract Article PDF–1.7M

Select item 60965005.

Hepatocyte nuclear factors as possible C-reactive protein transcriptional inducer in the liver and white adipose tissue of rats with experimental chronic renal failure

Elzbieta Sucajtys-Szulc, Alicja Debska-Slizien, Boleslaw Rutkowski, Ryszard Milczarek, Iwona Pelikant-Malecka, Tomasz Sledzinski, Julian Swierczynski, Marek Szolkiewicz

Mol Cell Biochem. 2018; 446(1): 11–23. Published online 2018 Jan 12. doi: 10.1007/s11010-018-3268-1

PMCID:: PMC6096500

Abstract Article PDF–1.1M

Select item 58226136.

The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1

Chen-Hong Ding, Chuan Yin, Shi-Jie Chen, Liang-Zhi Wen, Kai Ding, Shu-Juan Lei, Jin-Pei Liu, Jian Wang, Kai-xian Chen, Hua-liang Jiang, Xin Zhang, Cheng Luo, Wei-Fen Xie

Mol Cancer. 2018; 17: 63. Published online 2018 Feb 21. doi: 10.1186/s12943-018-0813-1

PMCID:: PMC5822613

Abstract Article PDF–5.0M

Select item 56413357.

Improved Progression-Free Survival in Irinotecan-Treated Metastatic Colorectal Cancer Patients Carrying the HNF1A Coding Variant p.I27L

Adrien Labriet, Elena De Mattia, Erika Cecchin, Éric Lévesque, Derek Jonker, Félix Couture, Angela Buonadonna, Mario D’Andrea, Lyne Villeneuve, Giuseppe Toffoli, Chantal Guillemette

Front Pharmacol. 2017; 8: 712. Published online 2017 Oct 10. doi: 10.3389/fphar.2017.00712

PMCID:: PMC5641335

Abstract Article PDF–2.3M

Select item 54090838.

Hepatocyte nuclear factor 1α suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription

Cecilia Patitucci, Gabrielle Couchy, Alessia Bagattin, Tatiana Cañeque, Aurélien de Reyniès, Jean-Yves Scoazec, Raphaël Rodriguez, Marco Pontoglio, Jessica Zucman-Rossi, Mario Pende, Ganna Panasyuk

J Clin Invest. 2017 May 1; 127(5): 1873–1888. Published online 2017 Apr 10. doi: 10.1172/JCI90327

PMCID:: PMC5409083

Abstract Article PDF–4.0M

Select item 41514859.

A Polymorphism in Hepatocyte Nuclear Factor 1 Alpha, rs7310409, Is Associated with Left Main Coronary Artery Disease

Rui Liu, Hanning Liu, Haiyong Gu, Xiao Teng, Yu Nie, Zhou Zhou, Yan Zhao, Shengshou Hu, Zhe Zheng

Biochem Res Int. 2014; 2014: 924105. Published online 2014 Aug 18. doi: 10.1155/2014/924105

PMCID:: PMC4151485

Abstract Article PDF–669K

Select item 348354610.

Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules

Andre J. Faure, Dominic Schmidt, Stephen Watt, Petra C. Schwalie, Michael D. Wilson, Huiling Xu, Robert G. Ramsay, Duncan T. Odom, Paul Flicek

Genome Res. 2012 Nov; 22(11): 2163–2175. doi: 10.1101/gr.136507.111

PMCID:: PMC3483546

Abstract Article PDF–1.2M

Select item 339110411.

Anks4b, a Novel Target of HNF4α Protein, Interacts with GRP78 Protein and Regulates Endoplasmic Reticulum Stress-induced Apoptosis in Pancreatic β-Cells

Yoshifumi Sato, Mitsutoki Hatta, Md. Fazlul Karim, Tomohiro Sawa, Fan-Yan Wei, Shoki Sato, Mark A. Magnuson, Frank J. Gonzalez, Kazuhito Tomizawa, Takaaki Akaike, Tatsuya Yoshizawa, Kazuya Yamagata

J Biol Chem. 2012 Jun 29; 287(27): 23236–23245. Published online 2012 May 15. doi: 10.1074/jbc.M112.368779

PMCID:: PMC3391104

Abstract Article PDF–2.4M

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317315213.

Hepatic Nuclear Factor 1α (HNF1α) Dysfunction Down-regulates X-box-binding Protein 1 (XBP1) and Sensitizes β-Cells to Endoplasmic Reticulum Stress

Clare L. Kirkpatrick, Andreas Wiederkehr, Mathurin Baquié, Dmitry Akhmedov, Haiyan Wang, Benoit R. Gauthier, Ildem Akerman, Hisamitsu Ishihara, Jorge Ferrer, Claes B. Wollheim

J Biol Chem. 2011 Sep 16; 286(37): 32300–32312. Published online 2011 Jul 22. doi: 10.1074/jbc.M111.247866

PMCID:: PMC3173152

Abstract Article PDF–2.1M

Select item 314165614.

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

Saul Kivimäe, Xiao Yong Yang, Benjamin NR Cheyette

BMC Biochem. 2011; 12: 33. Published online 2011 Jun 30. doi: 10.1186/1471-2091-12-33

PMCID:: PMC3141656

Abstract Article PDF–3.2M

Select item 313832515.

Bone Morphogenetic Protein 3 Controls Insulin Gene Expression and Is Down-regulated in INS-1 Cells Inducibly Expressing a Hepatocyte Nuclear Factor 1A–Maturity-onset Diabetes of the Young Mutation

Caroline Bonner, Angela M. Farrelly, Caoimhín G. Concannon, Heiko Dussmann, Mathurin Baquié, Isabelle Virard, Hella Wobser, Donat Kögel, Claes B. Wollheim, Marjan Rupnik, Maria M. Byrne, Hans-Georg König, Jochen H. M. Prehn

J Biol Chem. 2011 Jul 22; 286(29): 25719–25728. Published online 2011 May 31. doi: 10.1074/jbc.M110.215525

PMCID:: PMC3138325

Abstract Article PDF–1.3M

Select item 302279716.

HNF1A G319S variant, active cigarette smoking and incident type 2 diabetes in Aboriginal Canadians: a population-based epidemiological study

Sylvia H Ley, Robert A Hegele, Stewart B Harris, Mary Mamakeesick, Henian Cao, Philip W Connelly, Joel Gittelsohn, Ravi Retnakaran, Bernard Zinman, Anthony J Hanley

BMC Med Genet. 2011; 12: 1. Published online 2011 Jan 5. doi: 10.1186/1471-2350-12-1

PMCID:: PMC3022797

Abstract Article PDF–194K

Select item 297524217.

AMP-activated Protein Kinase Mediates Apoptosis in Response to Bioenergetic Stress through Activation of the Pro-apoptotic Bcl-2 Homology Domain-3-only Protein BMF

Seán M. Kilbride, Angela M. Farrelly, Caroline Bonner, Manus W. Ward, Kristine C. Nyhan, Caoimhín G. Concannon, Claes B. Wollheim, Maria M. Byrne, Jochen H. M. Prehn

J Biol Chem. 2010 Nov 12; 285(46): 36199–36206. Published online 2010 Sep 14. doi: 10.1074/jbc.M110.138107

PMCID:: PMC2975242

Abstract Article PDF–1.3M

Select item 293992818.

Hepatocyte nuclear factor-4α interacts with other hepatocyte nuclear factors in regulating transthyretin gene expression

Zhongyan Wang, Peter A. Burke

FEBS J. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: FEBS J. 2010 Oct; 277(19): 4066–4075. Published online 2010 Aug 23. doi: 10.1111/j.1742-4658.2010.07802.x

PMCID:: PMC2939928

Abstract Article PDF–1.4M

Select item 292921919.

Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study

Sylvia H Ley, Robert A Hegele, Philip W Connelly, Stewart B Harris, Mary Mamakeesick, Henian Cao, Joel Gittelsohn, Ravi Retnakaran, Bernard Zinman, Anthony J Hanley

Cardiovasc Diabetol. 2010; 9: 39. Published online 2010 Aug 18. doi: 10.1186/1475-2840-9-39