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Items: 1 to 20 of 136

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
LncRNA AP000842.3 Triggers the Malignant Progression of Prostate Cancer by Regulating Cuproptosis Related Gene NFAT5
Gaobo Zhou, Chaoqian Chen, Hongjian Wu, Jiao Lin, Hang Liu, Yiran Tao, Bin Huang
Technol Cancer Res Treat. 2024; 23: 15330338241255585. Published online 2024 May 23. doi: 10.1177/15330338241255585
PMCID:
PMC11119409
AbstractArticlePDF–5.0M
3.
Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells
Toshiyuki Okumura, Janet P. Raja Xavier, Jana Pasternak, Zhiqi Yang, Cao Hang, Bakhtiyor Nosirov, Yogesh Singh, Jakob Admard, Sara Y. Brucker, Stefan Kommoss, Satoru Takeda, Annette Staebler, Florian Lang, Madhuri S. Salker
Int J Mol Sci. 2024 Apr; 25(7): 3666. Published online 2024 Mar 25. doi: 10.3390/ijms25073666
PMCID:
PMC11012216
AbstractArticlePDF–6.0M
4.
TonEBP/NFAT5 expression is associated with cisplatin resistance and migration in macrophage-induced A549 cells
Hee Ju Song, Young Hwan Kim, Han Na Choi, Taehee Kim, Soo Jin Kim, Min Woong Kang, Sang Do Lee
BMC Mol Cell Biol. 2024; 25: 6. Published online 2024 Mar 4. doi: 10.1186/s12860-024-00502-y
PMCID:
PMC10913585
AbstractArticlePDF–3.7M
5.
TonEBP: A Key Transcription Factor in Microglia Following Intracerebral Hemorrhage Induced-Neuroinflammation
Ailiyaer Palahati, Yujia Luo, Le Qin, Yuhao Duan, Mi Zhang, Hui Gan, Xuan Zhai
Int J Mol Sci. 2024 Feb; 25(3): 1438. Published online 2024 Jan 24. doi: 10.3390/ijms25031438
PMCID:
PMC10855931
AbstractArticlePDF–7.6M
6.
TonEBP expression is essential in the IL-1β–induced migration and invasion of human A549 lung cancer cells
HEE JU SONG, TAEHEE KIM, HAN NA CHOI, SOO JIN KIM, SANG DO LEE
Oncol Res. 2024; 32(1): 151–161. Published online 2023 Nov 15. doi: 10.32604/or.2023.030690
PMCID:
PMC10767233
AbstractArticlePDF–8.5M
7.
Lysine methylation promotes NFAT5 activation and determines temozolomide efficacy in glioblastoma
Yatian Li, Zhenyue Gao, Yuhong Wang, Bo Pang, Binbin Zhang, Ruxin Hu, Yuqing Wang, Chao Liu, Xuebin Zhang, Jingxuan Yang, Mei Mei, Yongzhi Wang, Xuan Zhou, Min Li, Yu Ren
Nat Commun. 2023; 14: 4062. Published online 2023 Jul 10. doi: 10.1038/s41467-023-39845-z
PMCID:
PMC10333326
AbstractArticlePDF–6.5M
8.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
9.
mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin
Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun
Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y
PMCID:
PMC10148843
AbstractArticlePDF–11M
10.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
11.
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz
Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7
PMCID:
PMC9290241
AbstractArticlePDF–8.2M
12.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
13.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
14.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
15.
Circular RNA_0037128 aggravates high glucose-induced damage in HK-2 cells via regulation of microRNA-497-5p/nuclear factor of activated T cells 5 axis
Tao Feng, Weifang Li, Tianyi Li, Wenjun Jiao, Sufang Chen
Bioengineered. 2021; 12(2): 10959–10970. Published online 2021 Nov 30. doi: 10.1080/21655979.2021.2001912
PMCID:
PMC8810043
AbstractArticlePDF–2.1M
16.
mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells
David A. Merle, Francesca Provenzano, Mohamed Ali Jarboui, Ellen Kilger, Simon J. Clark, Michela Deleidi, Angela Armento, Marius Ueffing
Antioxidants (Basel) 2021 Dec; 10(12): 1944. Published online 2021 Dec 3. doi: 10.3390/antiox10121944
PMCID:
PMC8750186
AbstractArticlePDF–2.7M
17.
NFAT5 Controls the Integrity of Epidermis
Khalid Muhammad, Delicia Xavier, Stefan Klein-Hessling, Muhammad Azeem, Tabea Rauschenberger, Krisna Murti, Andris Avots, Matthias Goebeler, Matthias Klein, Tobias Bopp, Malte Sielaff, Stefan Tenzer, Sigrid Möckel, José Aramburu, Cristina López-Rodríguez, Andreas Kerstan, Edgar Serfling
Front Immunol. 2021; 12: 780727. Published online 2021 Dec 9. doi: 10.3389/fimmu.2021.780727
PMCID:
PMC8696207
AbstractArticlePDF–21M
18.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
19.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
20.
The Role of Nuclear Factor of Activated T Cells 5 in Hyperosmotic Stress-Exposed Human Lens Epithelial Cells
Gyu-Nam Kim, Young-Sool Hah, Hyemin Seong, Woong-Sun Yoo, Mee-Young Choi, Hee-Young Cho, Seung Pil Yun, Seong-Jae Kim
Int J Mol Sci. 2021 Jun; 22(12): 6296. Published online 2021 Jun 11. doi: 10.3390/ijms22126296
PMCID:
PMC8230750
AbstractArticlePDF–4.8M

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