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Select item 107693501.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 106865732.

Lipid-anchored proteasomes control membrane protein homeostasis

Ruizhu Zhang, Shuxian Pan, Suya Zheng, Qingqing Liao, Zhaodi Jiang, Dixian Wang, Xuemei Li, Ao Hu, Xinran Li, Yezhang Zhu, Xiaoqi Shen, Jing Lei, Siming Zhong, Xiaomei Zhang, Lingyun Huang, Xiaorong Wang, Lan Huang, Li Shen, Bao-Liang Song, Jing-Wei Zhao, Zhiping Wang, Bing Yang, Xing Guo

Sci Adv. 2023 Dec 1; 9(48): eadj4605. Published online 2023 Nov 29. doi: 10.1126/sciadv.adj4605

PMCID:: PMC10686573

Abstract Article PDF–2.4M

Select item 103078523.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 94819334.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 90156995.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Abstract Article PDF–3.3M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74159918.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 66705649.

Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies

Lynn Bedford, David Hay, Anny Devoy, Simon Paine, Des G. Powe, Rashmi Seth, Trevor Gray, Ian Topham, Kevin Fone, Nooshin Rezvani, Maureen Mee, Tim Soane, Robert Layfield, Paul W. Sheppard, Ted Ebendal, Dmitry Usoskin, James Lowe, R. John Mayer

J Neurosci. 2008 Aug 13; 28(33): 8189–8198. doi: 10.1523/JNEUROSCI.2218-08.2008

PMCID:: PMC6670564

Abstract Article PDF–630K

Select item 655472310.

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca²⁺/CaM) and CaM Kinase II (CaMKII) Binding Partner

Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler

J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.

Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027

PMCID:: PMC6554723

Abstract Article PDF–2.0M

Select item 624418311.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 592777112.

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Nadine D Lauinger, Andrea I Krahn, Sepideh Valimehr, Aleksandar Rakovic, Isabelle Rouiller, Thomas M Durcan, Jean-François Trempe, Edward A Fon

eLife. 2018; 7: e32866. Published online 2018 Apr 20. doi: 10.7554/eLife.32866

PMCID:: PMC5927771

Abstract Article PDF–9.1M

Select item 585911113.

Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons

Philippine C. Geiszler, Aslihan Ugun-Klusek, Karen Lawler, Marie-Christine Pardon, Ding Yuchun, Li Bai, Clare A. Daykin, Dorothee P. Auer, Lynn Bedford

Sci Rep. 2018; 8: 4833. Published online 2018 Mar 19. doi: 10.1038/s41598-018-23155-2

PMCID:: PMC5859111

Abstract Article PDF–3.2M

Select item 579902314.

Chemical cross-linking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue

Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Andrew Keller, Rong Tian, James E. Bruce

Cell Syst. Author manuscript; available in PMC 2019 Jan 24.

Published in final edited form as: Cell Syst. 2018 Jan 24; 6(1): 136–141.e5. Published online 2017 Nov 29. doi: 10.1016/j.cels.2017.10.017

PMCID:: PMC5799023

Abstract Article PDF–730K

Select item 538636015.

Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway

Aslihan Ugun-Klusek, Michael H Tatham, Jamal Elkharaz, Dumitru Constantin-Teodosiu, Karen Lawler, Hala Mohamed, Simon M L Paine, Glen Anderson, R John Mayer, James Lowe, E Ellen Billett, Lynn Bedford

Cell Death Dis. 2017 Jan; 8(1): e2531. Published online 2017 Jan 5. doi: 10.1038/cddis.2016.443

PMCID:: PMC5386360

Abstract Article PDF–2.2M

Select item 538122616.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 501612217.

Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4^CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration

Dolores Del Prete, Richard C. Rice, Anjali M. Rajadhyaksha, Luciano D'Adamio

J Biol Chem. 2016 Aug 12; 291(33): 17209–17227. Published online 2016 Jun 20. doi: 10.1074/jbc.M116.733626

PMCID:: PMC5016122

Abstract Article PDF–1.8M

Select item 495124218.

Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury

Shaogui Wang, Hong-Min Ni, Kenneth Dorko, Sean C. Kumer, Timothy M. Schmitt, Atta Nawabi, Masaaki Komatsu, Heqing Huang, Wen-Xing Ding

Oncotarget. 2016 Apr 5; 7(14): 17681–17698. Published online 2016 Jan 12. doi: 10.18632/oncotarget.6893

PMCID:: PMC4951242

Abstract Article PDF–12M

Select item 475234919.

TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory Subunit 4, Encoded by the PSMC1 Gene

Barbara Czub, Amna Z. Shah, Giovanna Alfano, Przemysław M. Kruczek, Christina F. Chakarova, Shomi S. Bhattacharya

PLoS One. 2016; 11(2): e0148678. Published online 2016 Feb 12. doi: 10.1371/journal.pone.0148678

PMCID:: PMC4752349

Abstract Article PDF–2.8M

Select item 474776820.

The LMO2 oncogene regulates DNA replication in hematopoietic cells

Marie-Claude Sincennes, Magali Humbert, Benoît Grondin, Véronique Lisi, Diogo F. T. Veiga, André Haman, Christophe Cazaux, Nazar Mashtalir, EL Bachir Affar, Alain Verreault, Trang Hoang

Proc Natl Acad Sci U S A. 2016 Feb 2; 113(5): 1393–1398. Published online 2016 Jan 13. doi: 10.1073/pnas.1515071113

PMCID:: PMC4747768

Abstract Article PDF–1.0M

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