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Select item 105615591.

Peptidylarginine Deiminase 2 Regulates Expression of DGCR8 Affecting miRNA Biogenesis in Gonadotrope Cells

Brett A. Ralston, Lamia Khan, Stanley B. DeVore, Trent A. Bronnenberg, Joseph W. Flock, Ari O. Sequoia, Paul R. Thompson, Amy M. Navratil, Brian D. Cherrington

Reproduction. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Reproduction. 2023 Aug 1; 166(2): 125–134. Published online 2023 Jul 3. doi: 10.1530/REP-22-0482

PMCID:: PMC10561559

Abstract Article PDF–1.8M

Select item 104038872.

RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization

Shuang Tao, Shu-Juan Xie, Li-Ting Diao, Guo Lv, Ya-Rui Hou, Yan-Xia Hu, Wan-Yi Xu, Bin Du, Zhen-Dong Xiao

J Exp Clin Cancer Res. 2023; 42: 194. Published online 2023 Aug 5. doi: 10.1186/s13046-023-02749-3

PMCID:: PMC10403887

Abstract Article PDF–8.9M

Select item 100380083.

Disparate insults relevant to schizophrenia converge on impaired spike synchrony and weaker synaptic interactions in prefrontal local circuits

Jennifer L. Zick, David A. Crowe, Rachael K. Blackman, Kelsey Schultz, David W. Bergstrand, Adele L. DeNicola, Russell E. Carter, Timothy J. Ebner, Lorene M. Lanier, Theoden I. Netoff, Matthew V. Chafee

Curr Biol. Author manuscript; available in PMC 2023 Mar 24.

Published in final edited form as: Curr Biol. 2022 Jan 10; 32(1): 14–25.e4. Published online 2021 Oct 21. doi: 10.1016/j.cub.2021.10.009

PMCID:: PMC10038008

Abstract Article PDF–1.7M

Select item 98009154.

The microRNA processing subunit DGCR8 is required for a T cell-dependent germinal center response

Patrick Daum, Shannon R. Ottmann, Julia Meinzinger, Sebastian R. Schulz, Joana Côrte-Real, Manuela Hauke, Edith Roth, Wolfgang Schuh, Dirk Mielenz, Hans-Martin Jäck, Katharina Pracht

Front Immunol. 2022; 13: 991347. Published online 2022 Dec 16. doi: 10.3389/fimmu.2022.991347

PMCID:: PMC9800915

Abstract Article PDF–2.6M

Select item 95344135.

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing

Jessica Kim, Masafumi Muraoka, Hajime Okada, Atsushi Toyoda, Rieko Ajima, Yumiko Saga

PLoS Genet. 2022 Oct; 18(10): e1009967. Published online 2022 Oct 5. doi: 10.1371/journal.pgen.1009967

PMCID:: PMC9534413

Abstract Article PDF–3.8M

Select item 84858586.

MicroRNA-directed pathway discovery elucidates an miR-221/222–mediated regulatory circuit in class switch recombination

Eric J. Wigton, Yohei Mikami, Ryan J. McMonigle, Carlos A. Castellanos, Adam K. Wade-Vallance, Simon K. Zhou, Robin Kageyama, Adam Litterman, Suparna Roy, Daisuke Kitamura, Emily C. Dykhuizen, Christopher D.C. Allen, Hui Hu, John J. O’Shea, K. Mark Ansel

J Exp Med. 2021 Nov 1; 218(11): e20201422. Published online 2021 Sep 29. doi: 10.1084/jem.20201422

PMCID:: PMC8485858

Abstract Article PDF–4.7M

Select item 84107617.

Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation

Kai P. Hoefig, Alexander Reim, Christian Gallus, Elaine H. Wong, Gesine Behrens, Christine Conrad, Meng Xu, Lisa Kifinger, Taku Ito-Kureha, Kyra A. Y. Defourny, Arie Geerlof, Josef Mautner, Stefanie M. Hauck, Dirk Baumjohann, Regina Feederle, Matthias Mann, Michael Wierer, Elke Glasmacher, Vigo Heissmeyer

Nat Commun. 2021; 12: 5208. Published online 2021 Sep 1. doi: 10.1038/s41467-021-25345-5

PMCID:: PMC8410761

Abstract Article PDF–16M

Select item 83132398.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82974449.

Global miRNA dosage control of embryonic germ layer specification

Yingzi Cui, Xuehui Lv, Li Ding, Lan Ke, Dechang Yang, Mehdi Pirouz, Ye Qi, Jennie Ong, Ge Gao, Peng Du, Richard I. Gregory

Nature. Author manuscript; available in PMC 2021 Nov 5.

Published in final edited form as: Nature. 2021 May; 593(7860): 602–606. Published online 2021 May 5. doi: 10.1038/s41586-021-03524-0

PMCID:: PMC8297444

Abstract Article PDF–5.2M

Select item 800894910.

DGCR8 deficiency impairs macrophage growth and unleashes the interferon response to mycobacteria

Barbara Killy, Barbara Bodendorfer, Jörg Mages, Kristina Ritter, Jonathan Schreiber, Christoph Hölscher, Katharina Pracht, Arif Ekici, Hans-Martin Jäck, Roland Lang

Life Sci Alliance. 2021 Jun; 4(6): e202000810. Published online 2021 Mar 26. doi: 10.26508/lsa.202000810

PMCID:: PMC8008949

Abstract Article PDF–2.9M

Select item 794122511.

Different Cre systems induce differential microRNA landscapes and abnormalities in the female reproductive tracts of Dgcr8 conditional knockout mice

Yeon Sun Kim, Seung Chel Yang, Mira Park, Youngsok Choi, Francesco J. DeMayo, John P. Lydon, Hye‐Ryun Kim, Hyunjung Jade Lim, Haengseok Song

Cell Prolif. 2021 Mar; 54(3): e12996. Published online 2021 Jan 26. doi: 10.1111/cpr.12996

PMCID:: PMC7941225

Abstract Article PDF–2.9M

Select item 793877012.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 722702813.

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931

PMCID:: PMC7227028

Abstract Article PDF–5.4M

Select item 713912014.

Genetic deletion of microRNA biogenesis in muscle cells reveals a hierarchical non-clustered network that controls focal adhesion signaling during muscle regeneration

Edlira Luca, Katarina Turcekova, Angelika Hartung, Sebastian Mathes, Hubert Rehrauer, Jan Krützfeldt

Mol Metab. 2020 Jun; 36: 100967. Published online 2020 Mar 5. doi: 10.1016/j.molmet.2020.02.010

PMCID:: PMC7139120

Abstract Article PDF–3.9M

Select item 702172715.

Schizophrenia-related microdeletion causes defective ciliary motility and brain ventricle enlargement via microRNA-dependent mechanisms in mice

Tae-Yeon Eom, Seung Baek Han, Jieun Kim, Jay A. Blundon, Yong-Dong Wang, Jing Yu, Kara Anderson, Damian B. Kaminski, Sadie Miki Sakurada, Shondra M. Pruett-Miller, Linda Horner, Ben Wagner, Camenzind G. Robinson, Matthew Eicholtz, Derek C. Rose, Stanislav S. Zakharenko

Nat Commun. 2020; 11: 912. Published online 2020 Feb 14. doi: 10.1038/s41467-020-14628-y

PMCID:: PMC7021727

Abstract Article PDF–7.4M

Select item 665967316.

Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis

Liping Deng, Ruotong Ren, Zunpeng Liu, Moshi Song, Jingyi Li, Zeming Wu, Xiaoqing Ren, Lina Fu, Wei Li, Weiqi Zhang, Pedro Guillen, Juan Carlos Izpisua Belmonte, Piu Chan, Jing Qu, Guang-Hui Liu

Nat Commun. 2019; 10: 3329. Published online 2019 Jul 26. doi: 10.1038/s41467-019-10831-8