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Select item 111999551.

Modeling neurodegenerative and neurodevelopmental disorders in the Drosophila mushroom body

Aaron Stahl, Seth M. Tomchik

Learn Mem. 2024 May; 31(5): a053816. Published online 2024 May. doi: 10.1101/lm.053816.123

PMCID:: PMC11199955

Abstract Article PDF–937K

Select item 111961112.

The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila central nervous system

Sanjay Kumar Sukumar, Vimala Antonydhason, Linnea Molander, Jawdat Sandakly, Malak Kleit, Ganesh Umapathy, Patricia Mendoza-Garcia, Tafheem Masudi, Andreas Schlosser, Dick R Nässel, Christian Wegener, Margret Shirinian, Ruth H Palmer

eLife. 2024; 12: RP88985. Published online 2024 Jun 21. doi: 10.7554/eLife.88985

PMCID:: PMC11196111

Abstract Article PDF–22M

Select item 110984943.

Hypoxia delays steroid-induced developmental maturation in Drosophila by suppressing EGF signaling

Michael J. Turingan, Tan Li, Jenna Wright, Abhishek Sharma, Kate Ding, Shahoon Khan, Byoungchun Lee, Savraj S. Grewal

PLoS Genet. 2024 Apr; 20(4): e1011232. Published online 2024 Apr 26. doi: 10.1371/journal.pgen.1011232

PMCID:: PMC11098494

Abstract Article PDF–2.6M

Select item 109457564.

Timed receptor tyrosine kinase signaling couples the central and a peripheral circadian clock in Drosophila

Javier Cavieres-Lepe, Emad Amini, Maia Zabel, Dick R. Nässel, Ralf Stanewsky, Christian Wegener, John Ewer

Proc Natl Acad Sci U S A. 2024 Mar 12; 121(11): e2308067121. Published online 2024 Mar 5. doi: 10.1073/pnas.2308067121

PMCID:: PMC10945756

Abstract Article PDF–5.4M

Select item 106511105.

KDM5-mediated activation of genes required for mitochondrial biology is necessary for viability in Drosophila

Michael F. Rogers, Owen J. Marshall, Julie Secombe

Development. 2023 Nov 1; 150(21): dev202024. Published online 2023 Nov 6. doi: 10.1242/dev.202024

PMCID:: PMC10651110

Abstract Article

Select item 104820086.

Single-cell profiling of the developing embryonic heart in Drosophila

Xiaohu Huang, Yulong Fu, Hangnoh Lee, Yunpo Zhao, Wendy Yang, Joyce van de Leemput, Zhe Han

Development. 2023 Aug 15; 150(16): dev201936. Published online 2023 Aug 24. doi: 10.1242/dev.201936

PMCID:: PMC10482008

Abstract Article

Select item 104280717.

Neurofibromin 1 regulates early developmental sleep in Drosophila

Jaclyn Durkin, Amy R. Poe, Samuel J. Belfer, Anyara Rodriguez, Si Hao Tang, James A. Walker, Matthew S. Kayser

Neurobiol Sleep Circadian Rhythms. 2023 Nov; 15: 100101. Published online 2023 Aug 9. doi: 10.1016/j.nbscr.2023.100101

PMCID:: PMC10428071

Abstract Article PDF–8.8M

Select item 102809288.

Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS

Wenkai Yue, Xue Deng, Zhao Wang, Mingsheng Jiang, Rirong Hu, Yongjia Duan, Qiangqiang Wang, Jihong Cui, Yanshan Fang

Immun Ageing. 2023; 20: 27. Published online 2023 Jun 20. doi: 10.1186/s12979-023-00354-8

PMCID:: PMC10280928

Abstract Article PDF–9.0M

Select item 101102369.

Longitudinal fundus imaging and its genome-wide association analysis provide evidence for a human retinal aging clock

Sara Ahadi, Kenneth A Wilson, Boris Babenko, Cory Y McLean, Drew Bryant, Orion Pritchard, Ajay Kumar, Enrique M Carrera, Ricardo Lamy, Jay M Stewart, Avinash Varadarajan, Marc Berndl, Pankaj Kapahi, Ali Bashir

eLife. 2023; 12: e82364. Published online 2023 Apr 17. doi: 10.7554/eLife.82364

PMCID:: PMC10110236

Abstract Article PDF–4.0M

Select item 984498910.

Inter-organ Wingless/Ror/Akt signaling regulates nutrient-dependent hyperarborization of somatosensory neurons

Yasutetsu Kanaoka, Koun Onodera, Kaori Watanabe, Yusaku Hayashi, Tadao Usui, Tadashi Uemura, Yukako Hattori

eLife. 2023; 12: e79461. Published online 2023 Jan 17. doi: 10.7554/eLife.79461

PMCID:: PMC9844989

Abstract Article PDF–11M

Select item 958687911.

Updates on ion and water transport by the Malpighian tubule

Julian A T Dow, Sue Ann Krause, Pawel Herzyk

Curr Opin Insect Sci. 2021 Oct; 47: 31–37. doi: 10.1016/j.cois.2021.02.018

PMCID:: PMC9586879

Abstract Article

Select item 945831812.

Drosophila as a toolkit to tackle cancer and its metabolism

Hui Jiang, Taku Kimura, Han Hai, Ryodai Yamamura, Masahiro Sonoshita

Front Oncol. 2022; 12: 982751. Published online 2022 Aug 25. doi: 10.3389/fonc.2022.982751

PMCID:: PMC9458318

Abstract Article PDF–1.2M

Select item 940375113.

Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival

Kathrin Pfeifer, Georg Wolfstetter, Vimala Anthonydhason, Tafheem Masudi, Badrul Arefin, Mats Bemark, Patricia Mendoza-Garcia, Ruth H. Palmer

Dis Model Mech. 2022 Aug 1; 15(8): dmm049591. Published online 2022 Aug 16. doi: 10.1242/dmm.049591

PMCID:: PMC9403751

Abstract Article

Select item 932628814.

Endocrine cybernetics: neuropeptides as molecular switches in behavioural decisions

Dick R. Nässel, Meet Zandawala

Open Biol. 2022 Jul; 12(7): 220174. Published online July 27, 2022. doi: 10.1098/rsob.220174

PMCID:: PMC9326288

Abstract Article PDF–3.5M

Select item 924913215.

Alcohol-induced Aggression in Drosophila

Annie Park, Tracy Tran, Linda Gutierrez, Christopher J. Stojanik, Julian D. Y. Plyler, Grace A. Thompson, Rudolf A. Bohm, Elizabeth A. Scheuermann, Dean P. Smith, Nigel S. Atkinson

Addict Biol. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Addict Biol. 2021 Sep; 26(5): e13045. Published online 2021 May 27. doi: 10.1111/adb.13045

PMCID:: PMC9249132

Abstract Article PDF–1.0M

Select item 875849016.

Aberrant role of ALK in tau proteinopathy through autophagosomal dysregulation

Jisu Park, Hyunwoo Choi, Young Doo Kim, Seo-Hyun Kim, Youbin Kim, Youngdae Gwon, Dong Young Lee, Sung-Hye Park, Won Do Heo, Yong-Keun Jung

Mol Psychiatry. 2021; 26(10): 5542–5556. Published online 2021 Jan 15. doi: 10.1038/s41380-020-01003-y

PMCID:: PMC8758490

Abstract Article PDF–3.9M

Select item 872222417.

DamID transcriptional profiling identifies the Snail/Scratch transcription factor Kahuli as an Alk target in the Drosophila visceral mesoderm

Patricia Mendoza-Garcia, Swaraj Basu, Sanjay Kumar Sukumar, Badrul Arefin, Georg Wolfstetter, Vimala Anthonydhason, Linnea Molander, Ezgi Uçkun, Henrik Lindehell, Cristina Lebrero-Fernandez, Jan Larsson, Erik Larsson, Mats Bemark, Ruth H. Palmer

Development. 2021 Dec 1; 148(23): dev199465. Published online 2021 Dec 14. doi: 10.1242/dev.199465