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Select item 108448621.

mtDNA extramitochondrial replication mediates mitochondrial defect effects

Zhaoliang Shan, Shengnan Li, Yuxue Gao, Chunhua Jian, Xiuxiu Ti, Hui Zuo, Ying Wang, Guochun Zhao, Yan Wang, Qing Zhang

iScience. 2024 Feb 16; 27(2): 108970. Published online 2024 Jan 19. doi: 10.1016/j.isci.2024.108970

PMCID:: PMC10844862

Abstract Article PDF–8.0M

Select item 96530942.

Mitochondrial DNA maintenance in Drosophila melanogaster

Ana P.C. Rodrigues, Audrey C. Novaes, Grzegorz L. Ciesielski, Marcos T. Oliveira

Biosci Rep. 2022 Nov 30; 42(11): BSR20211693. Published online 2022 Nov 10. doi: 10.1042/BSR20211693

PMCID:: PMC9653094

Abstract Article PDF–1.3M

Select item 94057053.

Downregulating Mitochondrial DNA Polymerase γ in the Muscle Stimulated Autophagy, Apoptosis, and Muscle Aging-Related Phenotypes in Drosophila Adults

Mika Ozaki, Tuan Dat Le, Yoshihiro H. Inoue

Biomolecules. 2022 Aug; 12(8): 1105. Published online 2022 Aug 11. doi: 10.3390/biom12081105

PMCID:: PMC9405705

Abstract Article PDF–23M

Select item 86649164.

Exploiting a Y chromosome-linked Cas9 for sex selection and gene drive

Stephanie Gamez, Duverney Chaverra-Rodriguez, Anna Buchman, Nikolay P. Kandul, Stelia C. Mendez-Sanchez, Jared B. Bennett, Héctor M. Sánchez C., Ting Yang, Igor Antoshechkin, Jonny E. Duque, Philippos A. Papathanos, John M. Marshall, Omar S. Akbari

Nat Commun. 2021; 12: 7202. Published online 2021 Dec 10. doi: 10.1038/s41467-021-27333-1

PMCID:: PMC8664916

Abstract Article PDF–2.8M

Select item 86644865.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 79689246.

A confinable home-and-rescue gene drive for population modification

Nikolay P Kandul, Junru Liu, Jared B Bennett, John M Marshall, Omar S Akbari

eLife. 2021; 10: e65939. Published online 2021 Mar 5. doi: 10.7554/eLife.65939

PMCID:: PMC7968924

Abstract Article PDF–1.4M

Select item 77145297.

The DNA polymerases of Drosophila melanogaster

Steven J. Marygold, Helen Attrill, Elena Speretta, Kate Warner, Michele Magrane, Maria Berloco, Sue Cotterill, Mitch McVey, Yikang Rong, Masamitsu Yamaguchi

Fly (Austin) 2020; 14(1-4): 49–61. Published online 2020 Jan 14. doi: 10.1080/19336934.2019.1710076

PMCID:: PMC7714529

Abstract Article PDF–1.9M

Select item 71092638.

Drosophila as a Model System to Investigate the Effects of Mitochondrial Variation on Innate Immunity

Tiina S. Salminen, Pedro F. Vale

Front Immunol. 2020; 11: 521. Published online 2020 Mar 25. doi: 10.3389/fimmu.2020.00521

PMCID:: PMC7109263

Abstract Article PDF–1.0M

Select item 69615789.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 692647610.

A Genome-wide Screen Reveals that Reducing Mitochondrial DNA Polymerase Can Promote Elimination of Deleterious Mitochondrial Mutations

Ason C.-Y. Chiang, Eleanor McCartney, Patrick H. O'Farrell, Hansong Ma

Curr Biol. 2019 Dec 16; 29(24): 4330–4336.e3. doi: 10.1016/j.cub.2019.10.060

PMCID:: PMC6926476

Abstract Article

Select item 675092611.

Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis

Jia Zhou, Lingna Xu, Xiuying Duan, Wei Liu, Xiaocui Zhao, Xi Wang, Weina Shang, Xuefei Fang, Huan Yang, Lijun Jia, Jian Bai, Jiayao Zhao, Liquan Wang, Chao Tong

Sci Adv. 2019 Sep; 5(9): eaax0365. Published online 2019 Sep 18. doi: 10.1126/sciadv.aax0365

PMCID:: PMC6750926

Abstract Article PDF–14M

Select item 664387212.

A Genetic Screen Using the Drosophila melanogaster TRiP RNAi Collection To Identify Metabolic Enzymes Required for Eye Development

Rose C. Pletcher, Sara L. Hardman, Sydney F. Intagliata, Rachael L. Lawson, Aumunique Page, Jason M. Tennessen

G3 (Bethesda) 2019 Jul; 9(7): 2061–2070. Published online 2019 Apr 29. doi: 10.1534/g3.119.400193

PMCID:: PMC6643872

Abstract Article PDF–1.7M

Select item 634304413.

Towards comprehensive annotation of Drosophila melanogaster enzymes in FlyBase

Phani V Garapati, Jingyao Zhang, Alix J Rey, Steven J Marygold

Database (Oxford) 2019; 2019: bay144. Published online 2019 Jan 23. doi: 10.1093/database/bay144

PMCID:: PMC6343044

Abstract Article PDF–13M

Select item 628944914.

Deleterious mitochondrial DNA point mutations are overrepresented in Drosophila expressing a proofreading-defective DNA polymerase γ

Colby L. Samstag, Jake G. Hoekstra, Chiu-Hui Huang, Mark J. Chaisson, Richard J. Youle, Scott R. Kennedy, Leo J. Pallanck

PLoS Genet. 2018 Nov; 14(11): e1007805. Published online 2018 Nov 19. doi: 10.1371/journal.pgen.1007805

PMCID:: PMC6289449

Abstract Article PDF–2.4M

Select item 570780515.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900216.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 546723717.

Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c

Hongrui Meng, Chikara Yamashita, Kahori Shiba-Fukushima, Tsuyoshi Inoshita, Manabu Funayama, Shigeto Sato, Tomohisa Hatta, Tohru Natsume, Masataka Umitsu, Junichi Takagi, Yuzuru Imai, Nobutaka Hattori

Nat Commun. 2017; 8: 15500. Published online 2017 Jun 7. doi: 10.1038/ncomms15500