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Select item 113798821.

Two novel DnaJ chaperone proteins CG5001 and P58IPK regulate the pathogenicity of Huntington’s disease related aggregates

Ankita Deo, Rishita Ghosh, Snehal Ahire, Sayali Marathe, Amitabha Majumdar, Tania Bose

Sci Rep. 2024; 14: 20867. Published online 2024 Sep 6. doi: 10.1038/s41598-024-71065-3

PMCID:: PMC11379882

Abstract Article PDF–7.3M

Select item 111139822.

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10

So Young Lee, Juanma Ramirez, Maribel Franco, Benoît Lectez, Monika Gonzalez, Rosa Barrio, Ugo Mayor

Cell Mol Life Sci. 2014 Jul; 71(14): 2747–2758. Published online 2013 Dec 1. doi: 10.1007/s00018-013-1526-7

PMCID:: PMC11113982

Abstract Article PDF–1.7M

Select item 110349813.

Mrj is a chaperone of the Hsp40 family that regulates Orb2 oligomerization and long-term memory in Drosophila

Meghal Desai, Hemant, Ankita Deo, Jagyanseni Naik, Prathamesh Dhamale, Avinash Kshirsagar, Tania Bose, Amitabha Majumdar

PLoS Biol. 2024 Apr; 22(4): e3002585. Published online 2024 Apr 22. doi: 10.1371/journal.pbio.3002585

PMCID:: PMC11034981

Abstract Article PDF–4.0M

Select item 106985084.

A multi‐layered network model identifies Akt1 as a common modulator of neurodegeneration

Dokyun Na, Do‐Hwan Lim, Jae‐Sang Hong, Hyang‐Mi Lee, Daeahn Cho, Myeong‐Sang Yu, Bilal Shaker, Jun Ren, Bomi Lee, Jae Gwang Song, Yuna Oh, Kyungeun Lee, Kwang‐Seok Oh, Mi Young Lee, Min‐Seok Choi, Han Saem Choi, Yang‐Hee Kim, Jennifer M Bui, Kangseok Lee, Hyung Wook Kim, Young Sik Lee, Jörg Gsponer

Mol Syst Biol. 2023 Dec; 19(12): e11801. Published online 2023 Nov 20. doi: 10.15252/msb.202311801

PMCID:: PMC10698508

Abstract Article PDF–7.0M

Select item 102064075.

A global genetic interaction network by single-cell imaging and machine learning

Florian Heigwer, Christian Scheeder, Josephine Bageritz, Schayan Yousefian, Benedikt Rauscher, Christina Laufer, Sergi Beneyto-Calabuig, Maja Christina Funk, Vera Peters, Maria Boulougouri, Jana Bilanovic, Thilo Miersch, Barbara Schmitt, Claudia Blass, Fillip Port, Michael Boutros

Cell Syst. 2023 May 17; 14(5): 346–362.e6. doi: 10.1016/j.cels.2023.03.003

PMCID:: PMC10206407

Abstract Article

Select item 101655416.

Systematic analysis of YFP traps reveals common mRNA/protein discordance in neural tissues

Joshua S. Titlow, Maria Kiourlappou, Ana Palanca, Jeffrey Y. Lee, Dalia S. Gala, Darragh Ennis, Joyce J.S. Yu, Florence L. Young, David Miguel Susano Pinto, Sam Garforth, Helena S. Francis, Finn Strivens, Hugh Mulvey, Alex Dallman-Porter, Staci Thornton, Diana Arman, Marissa J. Millard, Aino I. Järvelin, Mary Kay Thompson, Martin Sargent, Ilias Kounatidis, Richard M. Parton, Stephen Taylor, Ilan Davis

J Cell Biol. 2023 Jun 5; 222(6): e202205129. Published online 2023 May 5. doi: 10.1083/jcb.202205129

PMCID:: PMC10165541

Abstract Article PDF–8.4M

Select item 95239977.

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang

Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x

PMCID:: PMC9523997

Abstract Article PDF–6.9M

Select item 94745458.

Mettl3-dependent m⁶A modification attenuates the brain stress response in Drosophila

Alexandra E. Perlegos, Emily J. Shields, Hui Shen, Kathy Fange Liu, Nancy M. Bonini

Nat Commun. 2022; 13: 5387. Published online 2022 Sep 14. doi: 10.1038/s41467-022-33085-3

PMCID:: PMC9474545

Abstract Article PDF–2.7M

Select item 94733589.

Clearance of variant Creutzfeldt–Jakob disease prions in vivo by the Hsp70 disaggregase system

Alana M Thackray, Brian Lam, Erin E McNulty, Amy V Nalls, Candace K Mathiason, Srivathsa Subramanya Magadi, Walker S Jackson, Olivier Andréoletti, Cristóbal Marrero-Winkens, Hermann Schätzl, Raymond Bujdoso

Brain. 2022 Sep; 145(9): 3236–3249. Published online 2022 Apr 21. doi: 10.1093/brain/awac144

PMCID:: PMC9473358

Abstract Article PDF–1.3M

Select item 929573410.

Identification of PSMB5 as a genetic modifier of fragile X–associated tremor/ataxia syndrome

Ha Eun Kong, Junghwa Lim, Alexander Linsalata, Yunhee Kang, Indranil Malik, Emily G. Allen, Yiqu Cao, Lisa Shubeck, Rich Johnston, Yanting Huang, Yanghong Gu, Xiangxue Guo, Michael E. Zwick, Zhaohui Qin, Thomas S. Wingo, Jorge Juncos, David L. Nelson, Michael P. Epstein, David J. Cutler, Peter K. Todd, Stephanie L. Sherman, Stephen T. Warren, Peng Jin

Proc Natl Acad Sci U S A. 2022 May 31; 119(22): e2118124119. Published online 2022 May 26. doi: 10.1073/pnas.2118124119

PMCID:: PMC9295734

Abstract Article PDF–2.3M

Select item 901959511.

Phylogenetic annotation of Drosophila melanogaster heat shock protein 70 genes

Gen Kaneko

MicroPubl Biol. 2022; 2022: 10.17912/micropub.biology.000558. Published online 2022 Apr 20. doi: 10.17912/micropub.biology.000558

PMCID:: PMC9019595

Abstract Article PDF–517K

Select item 866448612.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 862352513.

Heterogeneity in the Response of Different Subtypes of Drosophila melanogaster Midgut Cells to Viral Infections

João M. F. Silva, Tatsuya Nagata, Fernando L. Melo, Santiago F. Elena

Viruses. 2021 Nov; 13(11): 2284. Published online 2021 Nov 15. doi: 10.3390/v13112284

PMCID:: PMC8623525

Abstract Article PDF–7.7M

Select item 856531514.

ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD

Jumin Park, Jongbo Lee, Ji-hyung Kim, Jongbin Lee, Heeju Park, Chunghun Lim

Nucleic Acids Res. 2021 Nov 8; 49(19): 11294–11311. Published online 2021 Sep 22. doi: 10.1093/nar/gkab834

PMCID:: PMC8565315

Abstract Article PDF–8.3M

Select item 810494615.

Highly effective proximate labeling in Drosophila

Bo Zhang, Yuanbing Zhang, Ji-Long Liu

G3 (Bethesda) 2021 May; 11(5): jkab077. Published online 2021 Mar 16. doi: 10.1093/g3journal/jkab077

Correction in:: G3 (Bethesda). 2022 Mar; 12(3): jkac005.

PMCID:: PMC8104946

Abstract Article PDF–1.1M

Select item 806964816.

Genetic Screen in Adult Drosophila Reveals That dCBP Depletion in Glial Cells Mitigates Huntington Disease Pathology through a Foxo-Dependent Pathway

Elodie Martin, Raheleh Heidari, Véronique Monnier, Hervé Tricoire

Int J Mol Sci. 2021 Apr; 22(8): 3884. Published online 2021 Apr 9. doi: 10.3390/ijms22083884

PMCID:: PMC8069648

Abstract Article PDF–2.8M

Select item 806373517.

Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones

Unekwu M. Yakubu, Kevin A. Morano

J Biol Chem. 2021 Jan-Jun; 296: 100567. Published online 2021 Mar 19. doi: 10.1016/j.jbc.2021.100567

PMCID:: PMC8063735

Abstract Article PDF–2.4M

Select item 789631818.

The Krüppel-like factor Cabut has cell cycle regulatory properties similar to E2F1

Peng Zhang, Alexia J. Katzaroff, Laura A. Buttitta, Yiqin Ma, Huaqi Jiang, Derek W. Nickerson, Jan Inge Øvrebø, Bruce A. Edgar

Proc Natl Acad Sci U S A. 2021 Feb 16; 118(7): e2015675118. Published online 2021 Feb 8. doi: 10.1073/pnas.2015675118

PMCID:: PMC7896318

Abstract Article PDF–2.9M

Select item 733707119.

Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target

Mark W. Kankel, Anindya Sen, Lei Lu, Marina Theodorou, Douglas N. Dimlich, Alexander McCampbell, Christopher E. Henderson, Neil A. Shneider, Spyros Artavanis-Tsakonas

Genetics. 2020 Jul; 215(3): 747–766. Published online 2020 Apr 28. doi: 10.1534/genetics.119.302985

PMCID:: PMC7337071

Abstract Article PDF–2.6M

Select item 696157820.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

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