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Select item 96789971.

The role of tyrosine hydroxylase–dopamine pathway in Parkinson’s disease pathogenesis

Zhi Dong Zhou, Wuan Ting Saw, Patrick Ghim Hoe Ho, Zhi Wei Zhang, Li Zeng, Ya Yin Chang, Alfred Xu Yang Sun, Dong Rui Ma, Hong Yan Wang, Lei Zhou, Kah Leong Lim, Eng-King Tan

Cell Mol Life Sci. 2022; 79(12): 599. Published online 2022 Nov 21. doi: 10.1007/s00018-022-04574-x

PMCID:: PMC9678997

Abstract Article PDF–6.5M

Select item 96326582.

Exploring therapeutic potential of mitophagy modulators using Drosophila models of Parkinson’s disease

Jyotsna Asthana, Bhupendra V. Shravage

Front Aging Neurosci. 2022; 14: 986849. Published online 2022 Oct 19. doi: 10.3389/fnagi.2022.986849

PMCID:: PMC9632658

Abstract Article PDF–1.2M

Select item 84962773.

A cross-species approach for the identification of Drosophila male sterility genes

Kimihide Ibaraki, Mihoko Nakatsuka, Takashi Ohsako, Masahide Watanabe, Yu Miyazaki, Machi Shirakami, Timothy L Karr, Rikako Sanuki, Masatoshi Tomaru, Toshiyuki Takano-Shimizu-Kouno

G3 (Bethesda) 2021 Aug; 11(8): jkab183. Published online 2021 May 29. doi: 10.1093/g3journal/jkab183

PMCID:: PMC8496277

Abstract Article PDF–421K

Select item 82704844.

Loss of UCHL1 rescues the defects related to Parkinson’s disease by suppressing glycolysis

Su Jin Ham, Daewon Lee, Wen Jun Xu, Eunjoo Cho, Sekyu Choi, Soohong Min, Sunghyouk Park, Jongkyeong Chung

Sci Adv. 2021 Jul; 7(28): eabg4574. Published online 2021 Jul 9. doi: 10.1126/sciadv.abg4574

PMCID:: PMC8270484

Abstract Article PDF–7.4M

Select item 79983165.

The Importance of Drosophila melanogaster Research to UnCover Cellular Pathways Underlying Parkinson’s Disease

Melissa Vos, Christine Klein

Cells. 2021 Mar; 10(3): 579. Published online 2021 Mar 6. doi: 10.3390/cells10030579

PMCID:: PMC7998316

Abstract Article PDF–1.7M

Select item 70232336.

Antioxidant Therapy in Parkinson’s Disease: Insights from Drosophila melanogaster

Federica De Lazzari, Federica Sandrelli, Alexander J. Whitworth, Marco Bisaglia

Antioxidants (Basel) 2020 Jan; 9(1): 52. Published online 2020 Jan 7. doi: 10.3390/antiox9010052

PMCID:: PMC7023233

Abstract Article PDF–1.2M

Select item 65148877.

Dietary Macronutrient Management to Treat Mitochondrial Dysfunction in Parkinson’s Disease

Rijan Bajracharya, Neil A. Youngson, J. William O. Ballard

Int J Mol Sci. 2019 Apr; 20(8): 1850. Published online 2019 Apr 15. doi: 10.3390/ijms20081850

PMCID:: PMC6514887

Abstract Article PDF–1.0M

Select item 65078448.

Disease model organism for Parkinson disease: Drosophila melanogaster

Binod Aryal, Youngseok Lee

BMB Rep. 2019 Apr; 52(4): 250–258. Published online 2019 Apr 30. doi: 10.5483/BMBRep.2019.52.4.204

PMCID:: PMC6507844

Abstract Article PDF–838K

Select item 64986199.

Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the Drosophila approach

Zoi Evangelakou, Maria Manola, Sentiljana Gumeni, Ioannis P. Trougakos

Genes Nutr. 2019; 14: 12. Published online 2019 May 2. doi: 10.1186/s12263-019-0638-6

PMCID:: PMC6498619

Abstract Article PDF–2.3M

Select item 590001510.

Modeling Parkinson’s Disease in Drosophila: What Have We Learned for Dominant Traits?

Yulan Xiong, Jianzhong Yu

Front Neurol. 2018; 9: 228. Published online 2018 Apr 9. doi: 10.3389/fneur.2018.00228

PMCID:: PMC5900015

Abstract Article PDF–347K

Select item 589931611.

Abnormal visual gain control and excitotoxicity in early-onset Parkinson’s disease Drosophila models

Marc M. Himmelberg, Ryan J. H. West, Christopher J. H. Elliott, Alex R. Wade

J Neurophysiol. 2018 Mar 1; 119(3): 957–970. Published online 2017 Nov 15. doi: 10.1152/jn.00681.2017

PMCID:: PMC5899316

Abstract Article

Select item 570780512.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900213.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 557869914.

Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP⁺-dependent isocitrate dehydrogenase (IDH)

Jinsung Yang, Min Ju Kim, Woongchang Yoon, Eun Young Kim, Hyunjin Kim, Yoonjeong Lee, Boram Min, Kyung Shin Kang, Jin H. Son, Hwan Tae Park, Jongkyeong Chung, Hyongjong Koh

PLoS Genet. 2017 Aug; 13(8): e1006975. Published online 2017 Aug 21. doi: 10.1371/journal.pgen.1006975

PMCID:: PMC5578699

Abstract Article PDF–9.7M

Select item 541947215.

A Search for Genes Mediating the Growth-Promoting Function of TGFβ in the Drosophila melanogaster Wing Disc

Covadonga F. Hevia, Ana López-Varea, Nuria Esteban, Jose F. de Celis

Genetics. 2017 May; 206(1): 231–249. Published online 2017 Mar 16. doi: 10.1534/genetics.116.197228

PMCID:: PMC5419472

Abstract Article PDF–3.2M

Select item 524174216.

Evidence Against a Role for the Parkinsonism-associated Protein DJ-1 in Methylglyoxal Detoxification

Daniel H. Pfaff, Thomas Fleming, Peter Nawroth, Aurelio A. Teleman

J Biol Chem. 2017 Jan 13; 292(2): 685–690. Published online 2016 Nov 30. doi: 10.1074/jbc.M116.743823

PMCID:: PMC5241742

Abstract Article PDF–1.9M

Select item 488965817.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 485609318.

Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster

Janani Iyer, Qingyu Wang, Thanh Le, Lucilla Pizzo, Sebastian Grönke, Surendra S. Ambegaokar, Yuzuru Imai, Ashutosh Srivastava, Beatriz Llamusí Troisí, Graeme Mardon, Ruben Artero, George R. Jackson, Adrian M. Isaacs, Linda Partridge, Bingwei Lu, Justin P. Kumar, Santhosh Girirajan

G3 (Bethesda) 2016 May; 6(5): 1427–1437. Published online 2016 Mar 18. doi: 10.1534/g3.116.027060

PMCID:: PMC4856093

Abstract Article PDF–2.1M

Select item 469615219.

siRNA screen identifies QPCT as a druggable target for Huntington’s disease

Maria Jimenez-Sanchez, Wun Lam, Michael Hannus, Birte Sönnichsen, Sara Imarisio, Angeleen Fleming, Alessia Tarditi, Fiona Menzies, Teresa Ed Dami, Catherine Xu, Eduardo Gonzalez-Couto, Giulia Lazzeroni, Freddy Heitz, Daniela Diamanti, Luisa Massai, Venkata P. Satagopam, Guido Marconi, Chiara Caramelli, Arianna Nencini, Matteo Andreini, Gian Luca Sardone, Nicola P. Caradonna, Valentina Porcari, Carla Scali, Reinhard Schneider, Giuseppe Pollio, Cahir J. O’Kane, Andrea Caricasole, David C. Rubinsztein

Nat Chem Biol. Author manuscript; available in PMC 2015 Dec 30.

Published in final edited form as: Nat Chem Biol. 2015 May; 11(5): 347–354. Published online 2015 Apr 6. doi: 10.1038/nchembio.1790

PMCID:: PMC4696152

Abstract Article PDF–2.4M

Select item 465703420.

Classification of Parkinson’s Disease Genotypes in Drosophila Using Spatiotemporal Profiling of Vision

Ryan J.H. West, Christopher J.H. Elliott, Alex R. Wade

Sci Rep. 2015; 5: 16933. Published online 2015 Nov 24. doi: 10.1038/srep16933

PMCID:: PMC4657034

Abstract Article PDF–1.4M

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