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    Items: 1 to 20 of 287

    1.
    Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure
    Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer
    Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y
    PMCID:
    PMC11447256
    ArticlePDF–2.8M
    2.
    A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex
    Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll
    EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9
    PMCID:
    PMC11315929
    ArticlePDF–3.4M
    3.
    Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions
    Rose Wellens, Victor S. Tapia, Paula I. Seoane, Hayley Bennett, Antony Adamson, Graham Coutts, Jack Rivers-Auty, Martin Lowe, Jack P. Green, Gloria Lopez-Castejon, David Brough, Christopher Hoyle
    Nat Commun. 2024; 15: 6750. Published online 2024 Aug 8. doi: 10.1038/s41467-024-50901-0
    PMCID:
    PMC11310415
    ArticlePDF–4.3M
    4.
    ARID1A restrains EMT and stemness of ovarian cancer cells through the Hippo pathway
    Shouying Xu, Chongying Zhu, Qiang Xu, Zihao An, Shu Xu, Ge Xuan, Chao Lin, Chao Tang
    Int J Oncol. 2024 Aug; 65(2): 76. Published online 2024 Jun 14. doi: 10.3892/ijo.2024.5664
    PMCID:
    PMC11251745
    ArticlePDF–7.7M
    5.
    Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
    Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
    Cell. Author manuscript; available in PMC 2024 Oct 26.
    Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
    PMCID:
    PMC11209935
    ArticlePDF–3.0M
    6.
    Genome-wide DNA methylation in relation to ARID1A deficiency in ovarian clear cell carcinoma
    Shang Li, Gert Jan Meersma, Jolanta Kupryjanczyk, Steven de Jong, G. Bea A. Wisman
    J Transl Med. 2024; 22: 556. Published online 2024 Jun 10. doi: 10.1186/s12967-024-05311-7
    PMCID:
    PMC11163774
    ArticlePDF–4.6M
    7.
    ARID1A regulates DNA repair through chromatin organization and its deficiency triggers DNA damage-mediated anti-tumor immune response
    Ali Bakr, Giuditta Della Corte, Olivera Veselinov, Simge Kelekçi, Mei-Ju May Chen, Yu-Yu Lin, Gianluca Sigismondo, Marika Iacovone, Alice Cross, Rabail Syed, Yunhee Jeong, Etienne Sollier, Chun- Shan Liu, Pavlo Lutsik, Jeroen Krijgsveld, Dieter Weichenhan, Christoph Plass, Odilia Popanda, Peter Schmezer
    Nucleic Acids Res. 2024 Jun 10; 52(10): 5698–5719. Published online 2024 Apr 8. doi: 10.1093/nar/gkae233
    PMCID:
    PMC11162808
    ArticlePDF–7.7M
    8.
    Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
    YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
    Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
    PMCID:
    PMC11148184
    ArticlePDF–8.1M
    9.
    Deep‐targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma
    Menglin Xiao, Xiaoteng Cui, Can Xu, Lei Xin, Jixing Zhao, Shixue Yang, Biao Hong, Yanli Tan, Jie Zhang, Xiang Li, Jie Li, Chunsheng Kang, Chuan Fang
    CNS Neurosci Ther. 2024 Apr; 30(4): e14698. Published online 2024 Apr 11. doi: 10.1111/cns.14698
    PMCID:
    PMC11007544
    ArticlePDF–13M
    10.
    Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations
    Alessandro D’Ambrosio, Davide Bressan, Elisa Ferracci, Francesco Carbone, Patrizia Mulè, Federico Rossi, Caterina Barbieri, Elisa Sorrenti, Gaia Fiaccadori, Thomas Detone, Elena Vezzoli, Salvatore Bianchi, Chiara Sartori, Simona Corso, Akihisa Fukuda, Giovanni Bertalot, Andrea Falqui, Mattia Barbareschi, Alessandro Romanel, Diego Pasini, Fulvio Chiacchiera
    Sci Adv. 2024 Mar 15; 10(11): eadh4435. Published online 2024 Mar 15. doi: 10.1126/sciadv.adh4435
    PMCID:
    PMC10942108
    ArticlePDF–9.8M
    11.
    Interaction network of human early embryonic transcription factors
    Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
    EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0
    PMCID:
    PMC10933267
    ArticlePDF–2.9M
    12.
    Treatments, prognostic factors, and genetic heterogeneity in advanced cholangiocarcinoma: A multicenter real‐world study
    Alessandro Ottaiano, Mariachiara Santorsola, Anna Diana, Andrea Belli, Maria Luisa Lentini Graziano, Jessica Orefice, Renato Patrone, Annabella Di Mauro, Giosuè Scognamiglio, Fabiana Tatangelo, Mario De Bellis, Mauro Piccirillo, Francesco Fiore, Salvatore Stilo, Luca Tarotto, Marco Correra, Sara Di Lorenzo, Maurizio Capuozzo, Antonio Avallone, Lucrezia Silvestro, Antonella Bianco, Vincenza Granata, Piera Federico, Vincenzo Montesarchio, Bruno Daniele, Francesco Izzo, Guglielmo Nasti
    Cancer Med. 2024 Feb; 13(4): e6892. Published online 2024 Mar 8. doi: 10.1002/cam4.6892
    PMCID:
    PMC10923031
    ArticlePDF–904K
    13.
    ARID1A loss is associated with increased NRF2 signaling in human head and neck squamous cell carcinomas
    Vinh Nguyen, Travis P. Schrank, Michael B. Major, Bernard E. Weissman
    PLoS One. 2024; 19(2): e0297741. Published online 2024 Feb 15. doi: 10.1371/journal.pone.0297741
    PMCID:
    PMC10868765
    ArticlePDF–2.3M
    14.
    ARID1A loss induces P4HB to activate fibroblasts to support lung cancer cell growth, invasion, and chemoresistance
    Risheng Huang, Danni Wu, Kangliang Zhang, Guanqiong Hu, Yu Liu, Yi Jiang, Chichao Wang, Yuanliang Zheng
    Cancer Sci. 2024 Feb; 115(2): 439–451. Published online 2023 Dec 15. doi: 10.1111/cas.16052
    PMCID:
    PMC10859615
    ArticlePDF–4.5M
    15.
    The Role of the AT-Rich Interaction Domain 1A Gene (ARID1A) in Human Carcinogenesis
    Jing Jing Li, Cheok Soon Lee
    Genes (Basel) 2024 Jan; 15(1): 5. Published online 2023 Dec 19. doi: 10.3390/genes15010005
    PMCID:
    PMC10815128
    ArticlePDF–2.8M
    16.
    Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer
    Shasha Li, Lulu Wang, Jing Shi, Yi Chen, Ang Xiao, Bingyue Huo, Wenjing Tian, Shilu Zhang, Gang Yang, Wensheng Gong, Huixia Zhang
    PeerJ. 2024; 12: e16752. Published online 2024 Jan 10. doi: 10.7717/peerj.16752
    PMCID:
    PMC10787542
    ArticlePDF–13M
    17.
    ARID1A deficiency promotes progression and potentiates therapeutic antitumour immunity in hepatitis B virus-related hepatocellular carcinoma
    Tao Xing, Li Li, Xiaosong Rao, Jing Zhao, Yiran Chen, Gaoda Ju, Yaping Xu, Xuan Gao, Guilan Dong, Xuefeng Xia, Yanfang Guan, Lingling Zhang, Zhenping Wen, Jun Liang
    BMC Gastroenterol. 2024; 24: 11. Published online 2024 Jan 2. doi: 10.1186/s12876-023-03059-w
    PMCID:
    PMC10759659
    ArticlePDF–7.4M
    18.
    ARID1A loss activates MAPK signaling via DUSP4 downregulation
    Jayaprakash Mandal, Zheng-Cheng Yu, Ie-Ming Shih, Tian-Li Wang
    J Biomed Sci. 2023; 30: 94. Published online 2023 Dec 9. doi: 10.1186/s12929-023-00985-5
    PMCID:
    PMC10709884
    ArticlePDF–5.3M
    19.
    Targeting the TCA cycle through cuproptosis confers synthetic lethality on ARID1A-deficient hepatocellular carcinoma
    Tao Xing, Li Li, Yiran Chen, Gaoda Ju, Guilan Li, Xiaoyun Zhu, Yubo Ren, Jing Zhao, Zhilei Cheng, Yan Li, Da Xu, Jun Liang
    Cell Rep Med. 2023 Nov 21; 4(11): 101264. Published online 2023 Nov 7. doi: 10.1016/j.xcrm.2023.101264
    PMCID:
    PMC10694624
    ArticlePDF–6.5M
    20.
    Coexistent ARID1A-PIK3CA mutations are associated with immune-related pathways in luminal breast cancer
    Liat Anabel Sinberger, Tamar Zahavi, Amir Sonnenblick, Mali Salmon‐Divon
    Sci Rep. 2023; 13: 20911. Published online 2023 Nov 27. doi: 10.1038/s41598-023-48002-x
    PMCID:
    PMC10684499
    ArticlePDF–4.2M

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