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Select item 108282691.

In-vivo screening implicates endoribonuclease Regnase-1 in modulating senescence-associated lysosomal changes

Richard Venz, Anita Goyala, Abel Soto-Gamez, Tugce Yenice, Marco Demaria, Collin Y. Ewald

GeroScience. 2024 Apr; 46(2): 1499–1514. Published online 2023 Aug 29. doi: 10.1007/s11357-023-00909-z

PMCID:: PMC10828269

Abstract Article PDF–3.0M

Select item 95636352.

Mutant C. elegans p53 Together with Gain-of-Function GLP-1/Notch Decreases UVC-Damage-Induced Germline Cell Death but Increases PARP Inhibitor-Induced Germline Cell Death

Jorge Canar, Prima Manandhar-Sasaki, Jill Bargonetti

Cancers (Basel) 2022 Oct; 14(19): 4929. Published online 2022 Oct 8. doi: 10.3390/cancers14194929

PMCID:: PMC9563635

Abstract Article PDF–2.4M

Select item 93719013.

R-loop-induced irreparable DNA damage evades checkpoint detection in the C. elegans germline

Tara Hicks, Emily Koury, Caleb McCabe, Cameron Williams, Caroline Crahan, Sarit Smolikove

Nucleic Acids Res. 2022 Aug 12; 50(14): 8041–8059. Published online 2022 Jul 25. doi: 10.1093/nar/gkac621

PMCID:: PMC9371901

Abstract Article PDF–8.9M

Select item 92806954.

Histone Demethylase AMX-1 Regulates Fertility in a p53/CEP-1 Dependent Manner

Xiaojing Ren, Sisi Tian, Qinghao Meng, Hyun-Min Kim

Front Genet. 2022; 13: 929716. Published online 2022 Jun 30. doi: 10.3389/fgene.2022.929716

PMCID:: PMC9280695

Abstract Article PDF–2.3M

Select item 92179325.

SIN-3 functions through multi-protein interaction to regulate apoptosis, autophagy, and longevity in Caenorhabditis elegans

Chandrika Konwar, Jayant Maini, Surbhi Kohli, Vani Brahmachari, Daman Saluja

Sci Rep. 2022; 12: 10560. Published online 2022 Jun 22. doi: 10.1038/s41598-022-13864-0

PMCID:: PMC9217932

Abstract Article PDF–2.6M

Select item 91377216.

3,3′-Diindolylmethane Supplementation Maintains Oocyte Quality by Reducing Oxidative Stress and CEP-1/p53-Mediated Regulation of Germ Cells in a Reproductively Aged Caenorhabditis elegans Model

Mijin Lee, Esther Youn, Kyungsu Kang, Yhong-Hee Shim

Antioxidants (Basel) 2022 May; 11(5): 950. Published online 2022 May 11. doi: 10.3390/antiox11050950

PMCID:: PMC9137721

Abstract Article PDF–2.5M

Select item 90985007.

Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans

Silvia Maglioni, Alfonso Schiavi, Marlen Melcher, Vanessa Brinkmann, Zhongrui Luo, Anna Laromaine, Nuno Raimundo, Joel N. Meyer, Felix Distelmaier, Natascia Ventura

Nat Commun. 2022; 13: 2620. Published online 2022 May 12. doi: 10.1038/s41467-022-29972-4

PMCID:: PMC9098500

Abstract Article PDF–2.2M

Select item 90715298.

The zinc-finger transcription factor LSL-1 is a major regulator of the germline transcriptional program in Caenorhabditis elegans

David Rodriguez-Crespo, Magali Nanchen, Shweta Rajopadhye, Chantal Wicky

Genetics. 2022 May; 221(1): iyac039. Published online 2022 Mar 9. doi: 10.1093/genetics/iyac039

PMCID:: PMC9071529

Abstract Article PDF–2.5M

Select item 89912079.

Functional recovery of the germ line following splicing collapse

Wei Cao, Christopher Tran, Stuart K. Archer, Sandeep Gopal, Roger Pocock

Cell Death Differ. 2022 Apr; 29(4): 772–787. Published online 2021 Oct 18. doi: 10.1038/s41418-021-00891-z

PMCID:: PMC8991207

Abstract Article PDF–4.6M

Select item 886957410.

Self-DNA Exposure Induces Developmental Defects and Germline DNA Damage Response in Caenorhabditis elegans

Marcello Germoglio, Adele Adamo, Guido Incerti, Fabrizio Cartenì, Silvia Gigliotti, Aurora Storlazzi, Stefano Mazzoleni

Biology (Basel) 2022 Feb; 11(2): 262. Published online 2022 Feb 8. doi: 10.3390/biology11020262

PMCID:: PMC8869574

Abstract Article PDF–3.3M

Select item 884933711.

Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry

Antoine Baudrimont, Dimitra Paouneskou, Ariz Mohammad, Raffael Lichtenberger, Joshua Blundon, Yumi Kim, Markus Hartl, Sebastian Falk, Tim Schedl, Verena Jantsch

Sci Adv. 2022 Feb; 8(7): eabl8861. Published online 2022 Feb 16. doi: 10.1126/sciadv.abl8861

PMCID:: PMC8849337

Abstract Article PDF–7.2M

Select item 883441512.

Reproductive Toxicity of Furfural Acetone in Meloidogyne incognita and Caenorhabditis elegans

Wanli Cheng, Xue Yang, Hua Xue, Dian Huang, Minmin Cai, Feng Huang, Longyu Zheng, Ziniu Yu, Jibin Zhang

Cells. 2022 Feb; 11(3): 401. Published online 2022 Jan 25. doi: 10.3390/cells11030401

PMCID:: PMC8834415

Abstract Article PDF–1.8M

Select item 881696013.

Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy

Najmeh Soltanmohammadi, Siyao Wang, Björn Schumacher

Nat Commun. 2022; 13: 701. Published online 2022 Feb 4. doi: 10.1038/s41467-022-28225-8

Correction in:: Nat Commun. 2023; 14: 270.

PMCID:: PMC8816960

Abstract Article PDF–2.8M

Select item 881402614.

Mitochondrial protein import determines lifespan through metabolic reprogramming and de novo serine biosynthesis

Eirini Lionaki, Ilias Gkikas, Ioanna Daskalaki, Maria-Konstantina Ioannidi, Maria I. Klapa, Nektarios Tavernarakis

Nat Commun. 2022; 13: 651. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28272-1

PMCID:: PMC8814026

Abstract Article PDF–2.3M

Select item 828012415.

Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans

Tao Zhang, Cheng Ni, Cheng Li, Pan Lu, Dan Chen, Yuanlin Dong, Johnathan R. Whetstine, Yiying Zhang, Zhongcong Xie

Sci Rep. 2021; 11: 14481. Published online 2021 Jul 14. doi: 10.1038/s41598-021-93737-0

PMCID:: PMC8280124

Abstract Article PDF–2.4M

Select item 802521516.

DNA topoisomerase 3 is required for efficient germ cell quality control

Maria Rosaria Dello Stritto, Bernd Bauer, Pierre Barraud, Verena Jantsch

J Cell Biol. 2021 Jun 7; 220(6): e202012057. Published online 2021 Apr 2. doi: 10.1083/jcb.202012057

PMCID:: PMC8025215

Abstract Article PDF–6.3M

Select item 770862017.

Functional characterization of Caenorhabditis elegans cbs-2 gene during meiosis

Pamela Santonicola, Marcello Germoglio, Domenico Scotto d’Abbusco, Adele Adamo

Sci Rep. 2020; 10: 20913. Published online 2020 Dec 1. doi: 10.1038/s41598-020-78006-w

PMCID:: PMC7708620

Abstract Article PDF–5.0M

Select item 766049018.

The genetic paradigms of dietary restriction fail to extend life span in cep-1(gk138) mutant of C. elegans p53 due to possible background mutations

Anita Goyala, Aiswarya Baruah, Arnab Mukhopadhyay

PLoS One. 2020; 15(11): e0241478. Published online 2020 Nov 12. doi: 10.1371/journal.pone.0241478

PMCID:: PMC7660490

Abstract Article PDF–2.2M

Select item 726531119.

Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30

Yasmine J. Liu, Rebecca L. McIntyre, Georges E. Janssens, Evan G. Williams, Jiayi Lan, Michel van Weeghel, Bauke Schomakers, Henk van der Veen, Nicole N. van der Wel, Pallas Yao, William B. Mair, Ruedi Aebersold, Alyson W. MacInnes, Riekelt H. Houtkooper

J Cell Biol. 2020 Jun 1; 219(6): e201907067. Published online 2020 Apr 7. doi: 10.1083/jcb.201907067

PMCID:: PMC7265311

Abstract Article PDF–7.5M

Select item 689952420.

The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity

Aymeric P. Bailly, Aurelien Perrin, Marina Serrano-Macia, Chantal Maghames, Orsolya Leidecker, Helene Trauchessec, M.L. Martinez-Chantar, Anton Gartner, Dimitris P. Xirodimas

Cell Rep. 2019 Oct 1; 29(1): 212–224.e8. Published online 2019 Oct 1. doi: 10.1016/j.celrep.2019.08.070