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Items: 1 to 20 of 36

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Vesicular nucleotide transporter is a molecular target of eicosapentaenoic acid for neuropathic and inflammatory pain treatment
Yuri Kato, Kengo Ohsugi, Yuto Fukuno, Ken Iwatsuki, Yuika Harada, Takaaki Miyaji
Proc Natl Acad Sci U S A. 2022 Jul 26; 119(30): e2122158119. Published online 2022 Jul 18. doi: 10.1073/pnas.2122158119
PMCID:
PMC9335333
AbstractArticlePDF–1.1M
3.
Clodronate, an inhibitor of the vesicular nucleotide transporter, ameliorates steatohepatitis and acute liver injury
Nao Hasuzawa, Keita Tatsushima, Lixiang Wang, Masaharu Kabashima, Rie Tokubuchi, Ayako Nagayama, Kenji Ashida, Yoshihiro Ogawa, Yoshinori Moriyama, Masatoshi Nomura
Sci Rep. 2021; 11: 5192. Published online 2021 Mar 4. doi: 10.1038/s41598-021-83144-w
PMCID:
PMC7933178
AbstractArticlePDF–1.5M
4.
Live Imaging Reveals Cerebellar Neural Stem Cell Dynamics and the Role of VNUT in Lineage Progression
Lucía Paniagua-Herranz, Aida Menéndez-Méndez, Rosa Gómez-Villafuertes, Luis A. Olivos-Oré, Miguel Biscaia, Javier Gualix, Raquel Pérez-Sen, Esmerilda G. Delicado, Antonio R. Artalejo, María Teresa Miras-Portugal, Felipe Ortega
Stem Cell Reports. 2020 Nov 10; 15(5): 1080–1094. Published online 2020 Oct 15. doi: 10.1016/j.stemcr.2020.09.007
PMCID:
PMC7663791
AbstractArticlePDF–7.1M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
VNUT/SLC17A9, a vesicular nucleotide transporter, regulates osteoblast differentiation
Asako Inoue, Kayoko Nakao‐Kuroishi, Kaori Kometani‐Gunjigake, Masahiro Mizuhara, Tomohiko Shirakawa, Misa Ito‐Sago, Kazuma Yasuda, Mitsushiro Nakatomi, Takuma Matsubara, Yukiyo Tada‐Shigeyama, Kazumasa Morikawa, Shoichiro Kokabu, Tatsuo Kawamoto
FEBS Open Bio. 2020 Aug; 10(8): 1612–1623. Published online 2020 Jul 12. doi: 10.1002/2211-5463.12918
PMCID:
PMC7396442
AbstractArticlePDF–1.7M
7.
Transient Receptor Potential Vanilloid 4 Regulation of Adenosine Triphosphate Release by the Adenosine Triphosphate Transporter Vesicular Nucleotide Transporter, a Novel Therapeutic Target for Gastrointestinal Baroreception and Chronic Inflammation
Hiroshi Mihara, Ammar Boudaka, Makoto Tominaga, Toshiro Sugiyama
Digestion. 2020 Jan; 101(1): 6–11. Published online 2019 Nov 26. doi: 10.1159/000504021
PMCID:
PMC6979422
AbstractArticle
8.
Involvement of VNUT-exocytosis in transient receptor potential vanilloid 4-dependent ATP release from gastrointestinal epithelium
Hiroshi Mihara, Kunitoshi Uchida, Schuichi Koizumi, Yoshinori Moriyama
PLoS One. 2018; 13(10): e0206276. Published online 2018 Oct 26. doi: 10.1371/journal.pone.0206276
PMCID:
PMC6203352
AbstractArticlePDF–1.8M
9.
The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception
Kenta Maruyama, Yasunori Takayama, Erika Sugisawa, Yu Yamanoi, Takashi Yokawa, Takeshi Kondo, Ken-ichi Ishibashi, Bikash Ranjan Sahoo, Naoki Takemura, Yuki Mori, Hisashi Kanemaru, Yutaro Kumagai, Mikaël M. Martino, Yoshichika Yoshioka, Hisao Nishijo, Hiroki Tanaka, Atsushi Sasaki, Naohito Ohno, Yoichiro Iwakura, Yoshinori Moriyama, Masatoshi Nomura, Shizuo Akira, Makoto Tominaga
iScience. 2018 Aug 31; 6: 306–318. Published online 2018 Aug 15. doi: 10.1016/j.isci.2018.08.007
PMCID:
PMC6137711
AbstractArticlePDF–3.6M
10.
Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes
Manao Kinoshita, Yuri Hirayama, Kayoko Fujishita, Keisuke Shibata, Youichi Shinozaki, Eiji Shigetomi, Akiko Takeda, Ha Pham Ngoc Le, Hideaki Hayashi, Miki Hiasa, Yoshinori Moriyama, Kazuhiro Ikenaka, Kenji F. Tanaka, Schuichi Koizumi
EBioMedicine. 2018 Jun; 32: 72–83. Published online 2018 Jun 8. doi: 10.1016/j.ebiom.2018.05.036
PMCID:
PMC6020856
AbstractArticlePDF–2.6M
11.
Vesicular nucleotide transporter mediates ATP release and migration in neutrophils
Yuika Harada, Yuri Kato, Takaaki Miyaji, Hiroshi Omote, Yoshinori Moriyama, Miki Hiasa
J Biol Chem. 2018 Mar 9; 293(10): 3770–3779. Published online 2018 Jan 23. doi: 10.1074/jbc.M117.810168
PMCID:
PMC5846168
AbstractArticlePDF–2.0M
12.
Identification of a vesicular ATP release inhibitor for the treatment of neuropathic and inflammatory pain
Yuri Kato, Miki Hiasa, Reiko Ichikawa, Nao Hasuzawa, Atsushi Kadowaki, Ken Iwatsuki, Kazuhiro Shima, Yasuo Endo, Yoshiro Kitahara, Tsuyoshi Inoue, Masatoshi Nomura, Hiroshi Omote, Yoshinori Moriyama, Takaaki Miyaji
Proc Natl Acad Sci U S A. 2017 Aug 1; 114(31): E6297–E6305. Published online 2017 Jul 18. doi: 10.1073/pnas.1704847114
PMCID:
PMC5547629
AbstractArticlePDF–953K
13.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
14.
Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa
Tatsuya Ihara, Takahiko Mitsui, Yuki Nakamura, Satoru Kira, Hiroshi Nakagomi, Norifumi Sawada, Yuri Hirayama, Keisuke Shibata, Eiji Shigetomi, Yoichi Shinozaki, Mitsuharu Yoshiyama, Karl-Erik Andersson, Atsuhito Nakao, Masayuki Takeda, Schuichi Koizumi
PLoS One. 2017; 12(1): e0168234. Published online 2017 Jan 6. doi: 10.1371/journal.pone.0168234
PMCID:
PMC5218463
AbstractArticlePDF–2.6M
15.
Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain
Takahiro Masuda, Yui Ozono, Satsuki Mikuriya, Yuta Kohro, Hidetoshi Tozaki-Saitoh, Ken Iwatsuki, Hisayuki Uneyama, Reiko Ichikawa, Michael W. Salter, Makoto Tsuda, Kazuhide Inoue
Nat Commun. 2016; 7: 12529. Published online 2016 Aug 12. doi: 10.1038/ncomms12529
PMCID:
PMC4990655
AbstractArticlePDF–1.0M
16.
Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V‐ATPase generated voltage gradient as the driving force
Xi Zoë Zhong, Qi Cao, Xue Sun, Xian‐Ping Dong
J Physiol. 2016 Aug 1; 594(15): 4253–4266. Published online 2016 May 29. doi: 10.1113/JP271893
PMCID:
PMC4967729
AbstractArticlePDF–796K
17.
Increased levels of extracellular ATP in glaucomatous retinas: Possible role of the vesicular nucleotide transporter during the development of the pathology
María J. Pérez de Lara, Ana Guzmán-Aránguez, Pedro de la Villa, Juan Ignacio Díaz-Hernández, María Teresa Miras-Portugal, Jesús Pintor
Mol Vis. 2015; 21: 1060–1070. Published online 2015 Sep 2.
PMCID:
PMC4558477
AbstractArticlePDF–1.7M
18.
The vesicular nucleotide transporter (VNUT) is involved in the extracellular ATP effect on neuronal differentiation
Aida Menéndez-Méndez, Juan Ignacio Díaz-Hernández, M. Teresa Miras-Portugal
Purinergic Signal. 2015 Jun; 11(2): 239–249. Published online 2015 Apr 7. doi: 10.1007/s11302-015-9449-4
PMCID:
PMC4425722
AbstractArticlePDF–2.4M
19.
Impairment of vesicular ATP release affects glucose metabolism and increases insulin sensitivity
Shohei Sakamoto, Takaaki Miyaji, Miki Hiasa, Reiko Ichikawa, Akira Uematsu, Ken Iwatsuki, Atsushi Shibata, Hisayuki Uneyama, Ryoichi Takayanagi, Akitsugu Yamamoto, Hiroshi Omote, Masatoshi Nomura, Yoshinori Moriyama
Sci Rep. 2014; 4: 6689. Published online 2014 Oct 21. doi: 10.1038/srep06689
PMCID:
PMC4204045
AbstractArticlePDF–1.7M
20.
Role of vesicular nucleotide transporter VNUT (SLC17A9) in release of ATP from AR42J cells and mouse pancreatic acinar cells
K. A. Haanes, J. M. Kowal, G. Arpino, S. C. Lange, Y. Moriyama, P. A. Pedersen, I. Novak
Purinergic Signal. 2014 Sep; 10(3): 431–440. Published online 2014 Feb 2. doi: 10.1007/s11302-014-9406-7
PMCID:
PMC4152456
AbstractArticlePDF–5.6M

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