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Select item 105317031.

Human γS-Crystallin Mutation F10_Y11delinsLN in the First Greek Key Pair Destabilizes and Impairs Tight Packing Causing Cortical Lamellar Cataract

Venkata Pulla Rao Vendra, Christian Ostrowski, Marzena A. Dyba, Sergey G. Tarasov, J. Fielding Hejtmancik

Int J Mol Sci. 2023 Sep; 24(18): 14332. Published online 2023 Sep 20. doi: 10.3390/ijms241814332

PMCID:: PMC10531703

Abstract Article PDF–12M

Select item 99776912.

Human γS-Crystallin Resists Unfolding Despite Extensive Chemical Modification From Exposure To Ionizing Radiation

Brenna Norton-Baker, Megan A. Rocha, Jessica Granger-Jones, Dmitry A. Fishman, Rachel W. Martin

J Phys Chem B. Author manuscript; available in PMC 2023 Mar 2.

Published in final edited form as: J Phys Chem B. 2022 Jan 27; 126(3): 679–690. Published online 2022 Jan 13. doi: 10.1021/acs.jpcb.1c08157

PMCID:: PMC9977691

Abstract Article PDF–1.2M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78497224.

Stability of protein-specific hydration shell on crowding

Kuo-Ying Huang, Carolyn N. Kingsley, Ryan Sheil, Chi-Yuan Cheng, Jan C. Bierma, Kyle W. Roskamp, Domarin Khago, Rachel W. Martin, Songi Han

J Am Chem Soc. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: J Am Chem Soc. 2016 Apr 27; 138(16): 5392–5402. Published online 2016 Apr 19. doi: 10.1021/jacs.6b01989

PMCID:: PMC7849722

Abstract Article PDF–1.3M

Select item 74545585.

Cumulative deamidations of the major lens protein γS‐crystallin increase its aggregation during unfolding and oxidation

Calvin J. Vetter, David C. Thorn, Samuel G. Wheeler, Charlie C. Mundorff, Kate A. Halverson, Thomas E. Wales, Ujwal P. Shinde, John R. Engen, Larry L. David, John A. Carver, Kirsten J. Lampi

Protein Sci. 2020 Sep; 29(9): 1945–1963. Published online 2020 Aug 28. doi: 10.1002/pro.3915

PMCID:: PMC7454558

Abstract Article PDF–4.2M

Select item 74349826.

Human αB-crystallin discriminates between aggregation-prone and function-preserving variants of a client protein

Marc Sprague-Piercy, Eric Wong, Kyle W. Roskamp, Joseph Fakhoury, J. Alfredo Freites, Douglas J. Tobias, Rachel W. Martin

Biochim Biophys Acta Gen Subj. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Biochim Biophys Acta Gen Subj. 2020 Mar; 1864(3): 129502. Published online 2019 Dec 5. doi: 10.1016/j.bbagen.2019.129502

PMCID:: PMC7434982

Abstract Article PDF–3.0M

Select item 69367287.

Divalent cations and the divergence of βγ-crystallin function.

Kyle Roskamp, Natalia Kozlyuk, Suvrajit Sengupta, Jan C. Bierma, Rachel W. Martin

Biochemistry. Author manuscript; available in PMC 2020 Nov 12.

Published in final edited form as: Biochemistry. 2019 Nov 12; 58(45): 4505–4518. Published online 2019 Nov 1. doi: 10.1021/acs.biochem.9b00507

PMCID:: PMC6936728

Abstract Article PDF–2.1M

Select item 67006728.

Kinetic Stability of Long-Lived Human Lens γ-Crystallins and Their Isolated Double Greek Key Domains

Ishara A. Mills-Henry, Shannon L. Thol, Melissa S. Kosinski-Collins, Eugene Serebryany, Jonathan A. King

Biophys J. 2019 Jul 23; 117(2): 269–280. Published online 2019 Jun 14. doi: 10.1016/j.bpj.2019.06.006

PMCID:: PMC6700672

Abstract Article PDF–1.3M

Select item 60777229.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 576027010.

Deamidation of Human γS-Crystallin Increases Attractive Protein Interactions: Implications for Cataract

Ajay Pande, Natalya Mokhor, Jayanti Pande

Biochemistry. Author manuscript; available in PMC 2018 Jan 9.

Published in final edited form as: Biochemistry. 2015 Aug 11; 54(31): 4890–4899. Published online 2015 Jul 29. doi: 10.1021/acs.biochem.5b00185

PMCID:: PMC5760270

Abstract Article PDF–681K

Select item 464794111.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 395629612.

IN VITRO EVOLUTION OF AN HIV INTEGRASE BINDING PROTEIN FROM A LIBRARY OF C-TERMINAL DOMAIN γS-CRYSTALLIN VARIANTS

Issa S. Moody, Shawn C. Verde, Cathie M. Overstreet, W. Edward Robinson, Jr., Gregory A. Weiss

Bioorg Med Chem Lett. Author manuscript; available in PMC 2014 Mar 17.

Published in final edited form as: Bioorg Med Chem Lett. 2012 Sep 1; 22(17): 5584–5589. Published online 2012 Jul 10. doi: 10.1016/j.bmcl.2012.07.008

PMCID:: PMC3956296

Abstract Article PDF–1.3M

Select item 394033413.

Preferential and specific binding of human αB-crystallin to cataract-related variant of γS-crystallin

Carolyn N. Kingsley, William D. Brubaker, Stefan Markovic, Anne Diehl, Amanda J. Brindley, Hartmut Oschkinat, Rachel W. Martin

Structure. Author manuscript; available in PMC 2014 Dec 3.

Published in final edited form as: Structure. 2013 Dec 3; 21(12): 2221–2227. Published online 2013 Oct 31. doi: 10.1016/j.str.2013.09.017

PMCID:: PMC3940334

Abstract Article PDF–1.9M

Select item 392798914.

The Cataract-associated V41M mutant of human γS-crystallin shows specific structural changes that directly enhance local surface hydrophobicity

Somireddy Venkata Bharat, Alexander Shekhtman, Jayanti Pande

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Jan 3.

Published in final edited form as: Biochem Biophys Res Commun. 2014 Jan 3; 443(1): 110–114. Published online 2013 Nov 25. doi: 10.1016/j.bbrc.2013.11.073

PMCID:: PMC3927989

Abstract Article PDF–1.0M

Select item 388634115.

A Genome-Wide Association Study of Behavioral Disinhibition

Matt McGue, Yiwei Zhang, Michael B. Miller, Saonli Basu, Scott Vrieze, Brian Hicks, Steve Malone, William S. Oetting, William G. Iacono

Behav Genet. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Behav Genet. 2013 Sep; 43(5): 10.1007/s10519-013-9606-x. Published online 2013 Aug 14. doi: 10.1007/s10519-013-9606-x