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Select item 110309281.

Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients

Yuriy V. Shebzukhov, Inna N. Lavrik, Julia Karbach, Svetlana V. Khlgatian, Ekaterina P. Koroleva, Pavel V. Belousov, Kirill N. Kashkin, Alexander Knuth, Elke Jager, Nai-Wen Chi, Dmitry V. Kuprash, Sergei A. Nedospasov

Cancer Immunol Immunother. 2008 Jun; 57(6): 871–881. Published online 2007 Nov 20. doi: 10.1007/s00262-007-0423-z

PMCID:: PMC11030928

Abstract Article PDF–587K

Select item 101516152.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 93485763.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92456484.

Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation

Yan-Ran Xu, Meng-Ling Shi, Yu Zhang, Na Kong, Cong Wang, Yi-Feng Xiao, Shi-Shen Du, Qi-Yun Zhu, Cao-Qi Lei

Proc Natl Acad Sci U S A. 2022 Jun 28; 119(26): e2122805119. Published online 2022 Jun 21. doi: 10.1073/pnas.2122805119

PMCID:: PMC9245648

Abstract Article PDF–2.6M

Select item 88416335.

Down-regulation of hsa_circ_0045474 induces macrophage autophagy in tuberculosis via miR-582-5p/TNKS2 axis

Min Wu, Zhibin Liu, Shaojun Zhang

Innate Immun. 2022 Jan; 28(1): 11–18. Published online 2021 Dec 3. doi: 10.1177/17534259211064285

PMCID:: PMC8841633

Abstract Article PDF–1.9M

Select item 82792556.

MicroRNA-206 inhibits influenza A virus replication by targeting tankyrase 2

Gayan Bamunuarachchi, Xiaoyun Yang, Chaoqun Huang, Yurong Liang, Yujie Guo, Lin Liu

Cell Microbiol. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Cell Microbiol. 2021 Feb; 23(2): e13281. Published online 2020 Nov 4. doi: 10.1111/cmi.13281

PMCID:: PMC8279255

Abstract Article PDF–989K

Select item 82217367.

Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs

Arun A. Chandrakumar, Étienne Coyaud, Christopher B. Marshall, Mitsuhiko Ikura, Brian Raught, Robert Rottapel

J Cell Biol. 2021 Jul 5; 220(7): e202008037. Published online 2021 Jun 15. doi: 10.1083/jcb.202008037

PMCID:: PMC8221736

Abstract Article PDF–4.4M

Select item 81941708.

Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease

Ming Li, Chen Lyu, Manyan Huang, Catherine Do, Benjamin Tycko, Philip J. Lupo, Stewart L. MacLeod, Christopher E. Randolph, Nianjun Liu, John S. Witte, Charlotte A. Hobbs

BMC Genom Data. 2021; 22: 20. Published online 2021 Jun 10. doi: 10.1186/s12863-021-00975-2

PMCID:: PMC8194170

Abstract Article PDF–960K

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807305610.

Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex

Gleb Simanov, Irene Dang, Artem I. Fokin, Ksenia Oguievetskaia, Valérie Campanacci, Jacqueline Cherfils, Alexis M. Gautreau

Int J Mol Sci. 2021 Apr; 22(8): 4115. Published online 2021 Apr 16. doi: 10.3390/ijms22084115

PMCID:: PMC8073056

Abstract Article PDF–4.6M

Select item 804528311.

MicroRNA-490-3p inhibits migration and chemoresistance of colorectal cancer cells via targeting TNKS2

Jing Li, Rubing Mo, Linmei Zheng

World J Surg Oncol. 2021; 19: 117. Published online 2021 Apr 13. doi: 10.1186/s12957-021-02226-1

Correction in:: World J Surg Oncol. 2023; 21: 346.

PMCID:: PMC8045283

Abstract Article PDF–2.2M

Select item 794864812.

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1

Kevin Ryan, Ben Bolaňos, Marissa Smith, Prakash B. Palde, Paulina Delgado Cuenca, Todd L. VanArsdale, Sherry Niessen, Lianglin Zhang, Douglas Behenna, Martha A. Ornelas, Khanh T. Tran, Stephen Kaiser, Lawrence Lum, Al Stewart, Ketan S. Gajiwala

J Biol Chem. 2021 Jan-Jun; 296: 100251. Published online 2021 Jan 9. doi: 10.1074/jbc.RA120.016573

PMCID:: PMC7948648

Abstract Article PDF–2.3M

Select item 737807913.

A FRET-based high-throughput screening platform for the discovery of chemical probes targeting the scaffolding functions of human tankyrases

Sven T. Sowa, Carlos Vela-Rodríguez, Albert Galera-Prat, Mariana Cázares-Olivera, Renata Prunskaite-Hyyryläinen, Alexander Ignatev, Lari Lehtiö

Sci Rep. 2020; 10: 12357. Published online 2020 Jul 23. doi: 10.1038/s41598-020-69229-y

PMCID:: PMC7378079

Abstract Article PDF–1.6M

Select item 736760014.

Association of Relative Leucocyte Telomere Length and Gene Single Nucleotide Polymorphisms (TERT, TRF1, TNKS2) in Laryngeal Squamous Cell Carcinoma

PAULIUS VAICIULIS, RASA LIUTKEVICIENE, VYKINTAS LIUTKEVICIUS, ALVITA VILKEVICIUTE, GRETA GEDVILAITE, VIRGILIJUS ULOZA

Cancer Genomics Proteomics. 2020 Jul-Aug; 17(4): 431–439. Published online 2020 Jul 3. doi: 10.21873/cgp.20202

PMCID:: PMC7367600

Abstract Article PDF–193K

Select item 676120515.

Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling

Nan Li, Yifan Wang, Shinya Neri, Yuanli Zhen, Lon Wolf R. Fong, Yawei Qiao, Xu Li, Zhen Chen, Clifford Stephan, Weiye Deng, Rui Ye, Wen Jiang, Shuxing Zhang, Yonghao Yu, Mien-Chie Hung, Junjie Chen, Steven H. Lin

Nat Commun. 2019; 10: 4363. Published online 2019 Sep 25. doi: 10.1038/s41467-019-12377-1

PMCID:: PMC6761205

Abstract Article PDF–2.2M

Select item 669413216.

HENA, heterogeneous network-based data set for Alzheimer’s disease

Elena Sügis, Jerome Dauvillier, Anna Leontjeva, Priit Adler, Valerie Hindie, Thomas Moncion, Vincent Collura, Rachel Daudin, Yann Loe-Mie, Yann Herault, Jean-Charles Lambert, Henning Hermjakob, Tal Pupko, Jean-Christophe Rain, Ioannis Xenarios, Jaak Vilo, Michel Simonneau, Hedi Peterson

Sci Data. 2019; 6: 151. Published online 2019 Aug 14. doi: 10.1038/s41597-019-0152-0

PMCID:: PMC6694132

Abstract Article PDF–2.8M

Select item 625137017.

The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer

Fabian Christoph Franke, Johannes Müller, Miguel Abal, Eduardo Domínguez Medina, Ulrich Nitsche, Henri Weidmann, Solenne Chardonnet, Ewa Ninio, Klaus-Peter Janssen

Cell Mol Gastroenterol Hepatol. 2019; 7(1): 33–53. Published online 2018 Sep 11. doi: 10.1016/j.jcmgh.2018.08.007

PMCID:: PMC6251370

Abstract Article PDF–5.6M

Select item 616668218.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 613206919.

Regulation of Tankyrase activity by a catalytic domain dimer interface

Chen Fan, Nageswari Yarravarapu, Hua Chen, Ozlem Kulak, Pranathi Dasari, Jeremiah Herbert, Kiyoshi Yamaguchi, Lawrence Lum, Xuewu Zhang

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Sep 10.

Published in final edited form as: Biochem Biophys Res Commun. 2018 Sep 10; 503(3): 1780–1785. Published online 2018 Jul 26. doi: 10.1016/j.bbrc.2018.07.113

PMCID:: PMC6132069

Abstract Article PDF–1.0M

Select item 607001120.

Crosstalk between lysine methylation and phosphorylation of ATG16L1 dictates the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes

Huiwen Song, Xing Feng, Min Zhang, Xian Jin, Xiangdong Xu, Lin Wang, Xue Ding, Yunmei Luo, Fengqin Lin, Qin Wu, Guiyou Liang, Tian Yu, Qigong Liu, Zhiyong Zhang

Autophagy. 2018; 14(5): 825–844. Published online 2018 Apr 10. doi: 10.1080/15548627.2017.1389357

PMCID:: PMC6070011

Abstract Article PDF–3.1M

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