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Select item 105771081.

Fatty Acid-Binding Protein 4 is Essential for the Inflammatory and Metabolic Response of Microglia to Lipopolysaccharide

Yoshiteru Kagawa, Yi Ling Low, Jae Pyun, Umberto Doglione, Jennifer L. Short, Yijun Pan, Joseph A. Nicolazzo

J Neuroimmune Pharmacol. 2023; 18(3): 448–461. Published online 2023 Aug 9. doi: 10.1007/s11481-023-10079-6

PMCID:: PMC10577108

Abstract Article PDF–1.6M

Select item 105241272.

Desmoglein 2 Functions As A Receptor for Fatty Acid Binding Protein 4 in Breast Cancer Epithelial Cells

Dongmei Chen, Keith M. Wirth, Scott Kizy, Joseph M. Muretta, Todd W Markowski, Peter Yong, Adam Sheka, Hisham Abdelwahab, Ann V. Hertzel, Sayeed Ikramuddin, Masato Yamamoto, David A Bernlohr

Mol Cancer Res. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Mol Cancer Res. 2023 Aug 1; 21(8): 836–848. doi: 10.1158/1541-7786.MCR-22-0763

PMCID:: PMC10524127

Abstract Article PDF–2.1M

Select item 104438033.

Endothelial-derived FABP4 constitutes the majority of basal circulating hormone and regulates lipolysis-driven insulin secretion

Karen E. Inouye, Kacey J. Prentice, Alexandra Lee, Zeqiu B. Wang, Carla Dominguez-Gonzalez, Mu Xian Chen, Jillian K. Riveros, M. Furkan Burak, Grace Y. Lee, Gökhan S. Hotamışlıgil

JCI Insight. 2023 Jul 24; 8(14): e164642. Published online 2023 Jul 24. doi: 10.1172/jci.insight.164642

PMCID:: PMC10443803

Abstract Article PDF–7.3M

Select item 102488694.

Sympathetic tone dictates the impact of lipolysis on FABP4 secretion

Kacey J. Prentice, Alexandra Lee, Paulina Cedillo, Karen E. Inouye, Meric Erikci Ertunc, Jillian K. Riveros, Grace Yankun Lee, Gökhan S. Hotamisligil

J Lipid Res. 2023 Jun; 64(6): 100386. Published online 2023 May 10. doi: 10.1016/j.jlr.2023.100386

PMCID:: PMC10248869

Abstract Article PDF–1.2M

Select item 99682975.

Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation

Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim, Joon-Sup Yoon, Ji-Min Lee, Se Jin Im, Ho Lee, Min-Woo Lee, Chang-Woo Lee

Nat Commun. 2023; 14: 1097. Published online 2023 Feb 25. doi: 10.1038/s41467-023-36836-y

PMCID:: PMC9968297

Abstract Article PDF–4.4M

Select item 99619236.

RNAseq Analysis of FABP4 Knockout Mouse Hippocampal Transcriptome Suggests a Role for WNT/β-Catenin in Preventing Obesity-Induced Cognitive Impairment

Simon W. So, Joshua P. Nixon, David A. Bernlohr, Tammy A. Butterick

Int J Mol Sci. 2023 Feb; 24(4): 3381. Published online 2023 Feb 8. doi: 10.3390/ijms24043381

PMCID:: PMC9961923

Abstract Article PDF–1.0M

Select item 97948247.

Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages

Wei Feng, Abha Bais, Haoting He, Cassandra Rios, Shan Jiang, Juan Xu, Cindy Chang, Dennis Kostka, Guang Li

Nat Commun. 2022; 13: 7960. Published online 2022 Dec 27. doi: 10.1038/s41467-022-35691-7

PMCID:: PMC9794824

Abstract Article PDF–17M

Select item 96354628.

FABP4 in Paneth cells regulates antimicrobial protein expression to reprogram gut microbiota

Xiaomin Su, Mengli Jin, Chen Xu, Yunhuan Gao, Yazheng Yang, Houbao Qi, Qianjing Zhang, Xiaorong Yang, Wang Ya, Yuan Zhang, Rongcun Yang

Gut Microbes. 2022; 14(1): 2139978. Published online 2022 Oct 31. doi: 10.1080/19490976.2022.2139978

PMCID:: PMC9635462

Abstract Article PDF–17M

Select item 93864649.

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang

Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548

PMCID:: PMC9386464

Abstract Article PDF–6.6M

Select item 932773710.

Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice

Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri

Biol Reprod. 2022 Jun; 106(6): 1292–1311. Published online 2022 Mar 16. doi: 10.1093/biolre/ioac056

PMCID:: PMC9327737

Abstract Article PDF–3.0M

Select item 920741311.

The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis

Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang

Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624

PMCID:: PMC9207413

Abstract Article PDF–6.0M

Select item 916196612.

Downregulation of fatty acid binding protein 4 alleviates lipid peroxidation and oxidative stress in diabetic retinopathy by regulating peroxisome proliferator-activated receptor γ-mediated ferroptosis

Xiao’e Fan, Manhong Xu, Qianfeng Ren, Yan Fan, Boshi Liu, Jiaqi Chen, Zhengmin Wang, Xiaoyan Sun

Bioengineered. 2022; 13(4): 10540–10551. Published online 2022 Apr 20. doi: 10.1080/21655979.2022.2062533

PMCID:: PMC9161966

Abstract Article PDF–3.8M

Select item 903218113.

Microglial FABP4-UCP2 Axis Modulates Neuroinflammation and Cognitive Decline in Obese Mice

Simon W. So, Kendra M. Fleming, Cayla M. Duffy, Joshua P. Nixon, David A. Bernlohr, Tammy A. Butterick

Int J Mol Sci. 2022 Apr; 23(8): 4354. Published online 2022 Apr 14. doi: 10.3390/ijms23084354

PMCID:: PMC9032181

Abstract Article PDF–3.3M

Select item 900174614.

Fatty acid-binding protein 4 is a therapeutic target for septic acute kidney injury by regulating inflammatory response and cell apoptosis

Bo Wang, Jun Xu, Qian Ren, Lu Cheng, Fan Guo, Yan Liang, Letian Yang, Zhouke Tan, Ping Fu, Liang Ma

Cell Death Dis. 2022 Apr; 13(4): 333. Published online 2022 Apr 11. doi: 10.1038/s41419-022-04794-w

PMCID:: PMC9001746

Abstract Article PDF–13M

Select item 895615415.

Mice with Fabp4-Cre Ablation of Arid5b are Resistant to Diet-Induced Obesity and Hepatic Steatosis

Robert H. Whitson, Jr., Shu-Lian Li, Guoxiang Zhang, Garrett P. Larson, Keiichi Itakura

Mol Cell Endocrinol. Author manuscript; available in PMC 2022 May 15.

Published in final edited form as: Mol Cell Endocrinol. 2021 May 15; 528: 111246. Published online 2021 Mar 20. doi: 10.1016/j.mce.2021.111246

PMCID:: PMC8956154

Abstract Article PDF–4.3M

Select item 869537916.

FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE^−/− mice atherosclerosis

Lingbo Xu, Huiping Zhang, Yanhua Wang, Anning Yang, Xiaoyan Dong, Lingyu Gu, Dayue Liu, Ning Ding, Yideng Jiang

Lab Invest. 2022; 102(1): 25–37. Published online 2021 Nov 1. doi: 10.1038/s41374-021-00679-2

PMCID:: PMC8695379

Abstract Article PDF–8.6M

Select item 853211517.

FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1β-induced chondrocytes by activating PPARγ to regulate the NF-κB signaling pathway

Huajie Mao, Bin Han, Hao Li, Yiqing Tao, Weigang Wu

Mol Med Rep. 2021 Dec; 24(6): 855. Published online 2021 Oct 14. doi: 10.3892/mmr.2021.12495

PMCID:: PMC8532115

Abstract Article PDF–5.7M

Select item 825972318.

Staufen1 unwinds the secondary structure and facilitates the translation of fatty acid binding protein 4 mRNA during adipogenesis

Xiaodi Liang, Yi Jiao, Xueli Gong, Hao Gu, Nuerbiye Nuermaimaiti, Xuanyu Meng, Dihui Liu, Yaqun Guan

Adipocyte. 2021; 10(1): 350–360. Published online 2021 Jul 5. doi: 10.1080/21623945.2021.1948165

PMCID:: PMC8259723

Abstract Article PDF–2.8M

Select item 825156219.

Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease

Evans Quilichini, Mélanie Fabre, Christoffer Nord, Thassadite Dirami, Axelle Le Marec, Silvia Cereghini, Raymond C Pasek, Maureen Gannon, Ulf Ahlgren, Cécile Haumaitre

J Pathol. 2021 May; 254(1): 31–45. Published online 2021 Mar 18. doi: 10.1002/path.5629

PMCID:: PMC8251562

Abstract Article PDF–46M

Select item 818819720.

Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells

Xiaoping Wu, Lingling Shu, Zixuan Zhang, Jingjing Li, Jiuyu Zong, Lai Yee Cheong, Dewei Ye, Karen S. L. Lam, Erfei Song, Cunchuan Wang, Aimin Xu, Ruby L. C. Hoo

Adv Sci (Weinh) 2021 Jun; 8(11): 2003721. Published online 2021 Mar 27. doi: 10.1002/advs.202003721