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Select item 113691741.

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations

Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak, Hanna Kuss, Marcel Diallo, Emma Rask, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2024 Sep; 20(9): 1025–1048. Published online 2024 Jul 15. doi: 10.1038/s44320-024-00055-4

PMCID:: PMC11369174

Abstract Article PDF–2.7M

Select item 112969142.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 112312653.

Validation of a novel NGS based BCR::ABL1 kinase domain mutation detection assay in Indian cohort

Pooja Chaudhary, Spandan Chaudhary, Falguni Patel, Shiv Patel, Toral Vaishnani, Nikha Trivedi, Dhiren Patel, Tushar Sonagara, Ashish Hirapara, Kavisha Vyas, Lokesh Patel, Raja Kumar, Nikkan Chakraborty, Divya Sharma, Jigar Suthar, Payal Kamdar, Ekta Jajodia, Firoz Ahmad, Neeraj Arora

Sci Rep. 2024; 14: 15745. Published online 2024 Jul 8. doi: 10.1038/s41598-024-66310-8

PMCID:: PMC11231265

Abstract Article PDF–1.6M

Select item 111594124.

Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer

Yuria Mano, Koji Takahashi, Nobuhisa Ishikawa, Atsushi Takano, Wataru Yasui, Kouki Inai, Hitoshi Nishimura, Eiju Tsuchiya, Yusuke Nakamura, Yataro Daigo

Cancer Sci. 2007 Dec; 98(12): 1902–1913. Published online 2007 Sep 20. doi: 10.1111/j.1349-7006.2007.00610.x

PMCID:: PMC11159412

Abstract Article PDF–688K

Select item 111290375.

Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway

Eman Hefni, Deepak Menon, Tao Ma, Emmanuel B. Asiedu, Ahmed Sultan, Timothy Meiller, Abraham Schneider, Akrit Sodhi, Silvia Montaner

Cell Signal. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Cell Signal. 2023 Aug; 108: 110697. Published online 2023 May 9. doi: 10.1016/j.cellsig.2023.110697

PMCID:: PMC11129037

Abstract Article PDF–1.6M

Select item 110335856.

Developmental trajectories and cooperating genomic events define molecular subtypes of BCR::ABL1-positive ALL

Lorenz Bastian, Thomas Beder, Malwine J. Barz, Sonja Bendig, Lorenz Bartsch, Wencke Walter, Nadine Wolgast, Björn Brändl, Christian Rohrandt, Björn-Thore Hansen, Alina M. Hartmann, Katharina Iben, Dennis Das Gupta, Miriam Denker, Johannes Zimmermann, Michael Wittig, Guranda Chitadze, Martin Neumann, Folker Schneller, Walter Fiedler, Björn Steffen, Matthias Stelljes, Christoph Faul, Stefan Schwartz, Franz-Josef Müller, Gunnar Cario, Lana Harder, Claudia Haferlach, Heike Pfeifer, Nicola Gökbuget, Monika Brüggemann, Claudia D. Baldus

Blood. 2024 Apr 4; 143(14): 1391–1398. Published online 2023 Dec 30. doi: 10.1182/blood.2023021752

PMCID:: PMC11033585

Abstract Article

Select item 107668367.

Spectrum of BCR-ABL mutations in Azerbaijanian imatinib-resistant patients with chronic myeloid leukemia

Aypara Hasanova, Chingiz Asadov, Nigar Karimova, Aytan Shirinova, Gunay Aliyeva, Zohra Alimirzoyeva

Pathol Oncol Res. 2023; 29: 1611518. Published online 2023 Dec 22. doi: 10.3389/pore.2023.1611518

PMCID:: PMC10766836

Abstract Article PDF–1.1M

Select item 106120368.

The Transmembrane Protease Serine 2 (TMPRSS2) Non-Protease Domains Regulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike-Mediated Virus Entry

Romano Strobelt, Julia Adler, Yosef Shaul

Viruses. 2023 Oct; 15(10): 2124. Published online 2023 Oct 19. doi: 10.3390/v15102124

PMCID:: PMC10612036

Abstract Article PDF–6.3M

Select item 105455329.

Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS

Helena Motaln, Urša Čerček, Alfred Yamoah, Priyanka Tripathi, Eleonora Aronica, Anand Goswami, Boris Rogelj

Brain. 2023 Oct; 146(10): 4088–4104. Published online 2023 Apr 18. doi: 10.1093/brain/awad130

PMCID:: PMC10545532

Abstract Article PDF–2.0M

Select item 1046073210.

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4

Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang

Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5

PMCID:: PMC10460732

Abstract Article PDF–5.6M

Select item 1039774111.

Emergence of BCR-ABL Kinase Domain Mutations Associated with Newly Diagnosed Chronic Myeloid Leukemia: A Meta-Analysis of Clinical Trials of Tyrosine Kinase Inhibitors

Iulia D. Ursan, Ruixuan Jiang, Evan M. Pickard, Todd A. Lee, Daniel Ng, A. Simon Pickard

J Manag Care Spec Pharm. 2015 Feb; 21(2): 10.18553/jmcp.2015.21.2.114. Published online 2015 Oct 16. doi: 10.18553/jmcp.2015.21.2.114

PMCID:: PMC10397741

Abstract Article PDF–284K

Select item 1037472212.

The interplay between telomeric complex members and BCR::ABL1 oncogenic tyrosine kinase in the maintenance of telomere length in chronic myeloid leukemia

Anna Deręgowska, Monika Pępek, Iwona Solarska, Marcin M. Machnicki, Katarzyna Pruszczyk, Marek Dudziński, Joanna Niesiobędzka-Krężel, Ilona Seferyńska, Waldemar Sawicki, Maciej Wnuk, Tomasz Stokłosa

J Cancer Res Clin Oncol. 2023; 149(10): 7103–7112. Published online 2023 Mar 5. doi: 10.1007/s00432-023-04662-w

PMCID:: PMC10374722

Abstract Article PDF–3.1M

Select item 1033388413.

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164

PMCID:: PMC10333884

Abstract Article PDF–5.0M

Select item 1012008314.

ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1

Benjamin Mayro, Jacob P. Hoj, Christian G. Cerda-Smith, Haley M. Hutchinson, Michael W. Caminear, Hannah L. Thrash, Peter S. Winter, Suzanne E. Wardell, Donald P. McDonnell, Colleen Wu, Kris C. Wood, Ann Marie Pendergast

Proc Natl Acad Sci U S A. 2023 Apr 18; 120(16): e2210418120. Published online 2023 Apr 11. doi: 10.1073/pnas.2210418120

PMCID:: PMC10120083

Abstract Article PDF–4.2M

Select item 1007290615.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 980750816.

Targeting the PTP1B‐Bcr‐Abl1 interaction for the degradation of T315I mutant Bcr‐Abl1 in chronic myeloid leukemia

Ahmed Elgehama, Yixuan Wang, Ying Yu, Lin Zhou, Zhixiu Chen, Liwei Wang, Lijun Sun, Jian Gao, Biao Yu, Yan Shen, Qiang Xu

Cancer Sci. 2023 Jan; 114(1): 247–258. Published online 2022 Sep 26. doi: 10.1111/cas.15580

PMCID:: PMC9807508

Abstract Article PDF–4.3M

Select item 977672117.

c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation

Saebom Lee, Hye Guk Ryu, Sin Ho Kweon, Hyerynn Kim, Hyeonwoo Park, Kyung-Ha Lee, Sang-Min Jang, Chan Hyun Na, Sangjune Kim, Han Seok Ko

Cells. 2022 Dec; 11(24): 3972. Published online 2022 Dec 8. doi: 10.3390/cells11243972

PMCID:: PMC9776721

Abstract Article PDF–2.9M

Select item 960803918.

Roles for c-Abl in postoperative neurodegeneration

Long Feng, Shihui Fu, Yao Yao, Yulong Li, Longhe Xu, Yali Zhao, Leiming Luo

Int J Med Sci. 2022; 19(12): 1753–1761. Published online 2022 Sep 28. doi: 10.7150/ijms.73740

PMCID:: PMC9608039

Abstract Article PDF–440K

Select item 936747819.

Molecular profile reveals immune-associated markers of medulloblastoma for different subtypes

Jinyi Chen, Zhuang Kang, Shenglan Li, Can Wang, Xiaohong Zheng, Zehao Cai, Lexin Pan, Feng Chen, Wenbin Li

Front Immunol. 2022; 13: 911260. Published online 2022 Jul 28. doi: 10.3389/fimmu.2022.911260

PMCID:: PMC9367478

Abstract Article PDF–20M

Select item 927928520.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

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