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Items: 1 to 20 of 162

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
IP3R-1 aggravates endotoxin-induced acute lung injury in mice by regulating MAM formation and mitochondrial function
Shuan Dong, Ya Wu, Yuan Zhang, Shaona Li, Qin Zhao, Shasha Liu, Yan Guo, Xiangyun Li, Kai Song, Lili Wu, Lina Wu, Jia Shi, Lirong Gong, Jianbo Yu
Exp Biol Med (Maywood) 2023 Dec; 248(23): 2262–2272. Published online 2023 Dec 30. doi: 10.1177/15353702231220667
PMCID:
PMC10903239
AbstractArticlePDF–4.5M
3.
Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B
Sayaka Tanaka, Hiroyuki Kabayama, Masahiro Enomoto, Nobuhito Saito, Katsuhiko Mikoshiba
J Physiol Sci. 2011 May; 61(3): 221–229. Published online 2011 Mar 20. doi: 10.1007/s12576-011-0140-4
PMCID:
PMC10717003
AbstractArticlePDF–642K
4.
IP3R1 underlies diastolic ANO1 activation and pressure-dependent chronotropy in lymphatic collecting vessels
Scott D. Zawieja, Grace A. Pea, Sarah E. Broyhill, Advaya Patro, Karen H. Bromert, Min Li, Charles E. Norton, Jorge A. Castorena-Gonzalez, Edward J. Hancock, Christopher D. Bertram, Michael J. Davis
J Gen Physiol. 2023 Dec 4; 155(12): e202313358. Published online 2023 Oct 18. doi: 10.1085/jgp.202313358
PMCID:
PMC10585095
AbstractArticlePDF–6.3M
5.
Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures
Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang
Neuron. Author manuscript; available in PMC 2023 Oct 19.
Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028
PMCID:
PMC9665885
AbstractArticlePDF–4.5M
6.
Binding of the erlin1/2 complex to the third intralumenal loop of IP3R1 triggers its ubiquitin-proteasomal degradation
Xiaokong Gao, Caden G. Bonzerato, Richard J.H. Wojcikiewicz
J Biol Chem. 2022 Jun; 298(6): 102026. Published online 2022 May 11. doi: 10.1016/j.jbc.2022.102026
PMCID:
PMC9168715
AbstractArticlePDF–4.4M
7.
IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming
Huayuan Tang, Yali Li, Shijia Wang, Jing Ji, Xiangbin Zhu, Yutong Bao, Can Huang, Ye Luo, Lei Huang, Yan Gao, Chaoliang Wei, Jie Liu, Xi Fang, Lu Sun, Kunfu Ouyang
iScience. 2022 May 20; 25(5): 104209. Published online 2022 Apr 6. doi: 10.1016/j.isci.2022.104209
PMCID:
PMC9046235
AbstractArticlePDF–3.2M
8.
DNA methylation in the pathophysiology of hyperphenylalaninemia in the PAHenu2 mouse model of phenylketonuria
S.F. Dobrowolski, J. Lyons-Weiler, K. Spridik, J. Vockley, K. Skvorak, A. Biery
Mol Genet Metab. Author manuscript; available in PMC 2022 Mar 28.
Published in final edited form as: Mol Genet Metab. 2016 Sep; 119(1-2): 1–7. Published online 2016 Jan 14. doi: 10.1016/j.ymgme.2016.01.001
PMCID:
PMC8958364
AbstractArticlePDF–346K
9.
IP3 receptor orchestrates maladaptive vascular responses in heart failure
Haikel Dridi, Gaetano Santulli, Jessica Gambardella, Stanislovas S. Jankauskas, Qi Yuan, Jingyi Yang, Steven Reiken, Xujun Wang, Anetta Wronska, Xiaoping Liu, Alain Lacampagne, Andrew R. Marks
J Clin Invest. 2022 Feb 15; 132(4): e152859. Published online 2022 Feb 15. doi: 10.1172/JCI152859
PMCID:
PMC8843748
AbstractArticlePDF–1.6M
10.
Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation
Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin
Sci Rep. 2021; 11: 22745. Published online 2021 Nov 23. doi: 10.1038/s41598-021-02218-x
PMCID:
PMC8610974
AbstractArticlePDF–2.5M
11.
Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle
Qian Wang, Wendy Wing Sze Yue, Zheng Jiang, Tian Xue, Shin H. Kang, Dwight E. Bergles, Katsuhiko Mikoshiba, Stefan Offermanns, King-Wai Yau
Curr Biol. Author manuscript; available in PMC 2021 Nov 9.
Published in final edited form as: Curr Biol. 2017 Jun 19; 27(12): 1791–1800.e5. Published online 2017 Jun 1. doi: 10.1016/j.cub.2017.05.022
PMCID:
PMC8577559
AbstractArticlePDF–1.7M
12.
IP3R-driven increases in mitochondrial Ca2+ promote neuronal death in NPC disease
Scott A. Tiscione, Maria Casas, Jonathan D. Horvath, Vincent Lam, Keiko Hino, Daniel S. Ory, L. Fernando Santana, Sergi Simó, Rose E. Dixon, Eamonn J. Dickson
Proc Natl Acad Sci U S A. 2021 Oct 5; 118(40): e2110629118. Published online 2021 Sep 27. doi: 10.1073/pnas.2110629118
PMCID:
PMC8501836
AbstractArticlePDF–6.3M
13.
Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers
Ruyi Mei, Linyu Huang, Mengyuan Wu, Chunxia Jiang, Aifen Yang, Huaping Tao, Kang Zheng, Junlin Yang, Wanhua Shen, Xianjun Chen, Xiaofeng Zhao, Mengsheng Qiu
Front Cell Neurosci. 2021; 15: 751439. Published online 2021 Sep 22. doi: 10.3389/fncel.2021.751439
PMCID:
PMC8492996
AbstractArticlePDF–3.0M
14.
Endophilin A2-mediated alleviation of endoplasmic reticulum stress-induced cardiac injury involves the suppression of ERO1α/IP3R signaling pathway
Yun Liu, Ruixiang Hu, Huanjia Shen, Qinxin Mo, Xinqiuyue Wang, Guiping Zhang, Sujuan Li, Guanfeng Liang, Ning Hou, Jiandong Luo
Int J Biol Sci. 2021; 17(13): 3672–3688. Published online 2021 Aug 26. doi: 10.7150/ijbs.60110
PMCID:
PMC8416715
AbstractArticlePDF–3.0M
15.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
16.
Deletion of IP3R1 by Pdgfrb-Cre in mice results in intestinal pseudo-obstruction and lethality
Hong Wang, Ran Jing, Christa Trexler, Yali Li, Huayuan Tang, Zhixiang Pan, Siting Zhu, Beili Zhao, Xi Fang, Jie Liu, Ju Chen, Kunfu Ouyang
J Gastroenterol. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: J Gastroenterol. 2019 May; 54(5): 407–418. Published online 2018 Oct 31. doi: 10.1007/s00535-018-1522-7
PMCID:
PMC8109192
AbstractArticlePDF–1.7M
17.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
18.
Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis
Cristine R. Casingal, Takako Kikkawa, Hitoshi Inada, Yukio Sasaki, Noriko Osumi
Mol Brain. 2020; 13: 167. Published online 2020 Dec 16. doi: 10.1186/s13041-020-00706-1
PMCID:
PMC7739466
AbstractArticlePDF–1.5M
19.
Inositol 1,4,5-Trisphosphate Receptor type 3 plays a protective role in hepatocytes during hepatic ischemia-reperfusion injury
Antônio Carlos Melo Lima Filho, Andressa França, Rodrigo M. Florentino, Marcone Loiola dos Santos, Fernanda de Oliveira Lemos, Dabny Goulart Missiaggia, Roberta Cristelli Fonseca, André Gustavo Oliveira, Meenakshisundaram Ananthanarayanam, Mateus T. Guerra, Matheus de Castro Fonseca, Paula Vieira Teixeira Vidigal, Cristiano Xavier Lima, Michael H. Nathanson, M. Fatima Leite
Cell Calcium. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: Cell Calcium. 2020 Nov; 91: 102264. Published online 2020 Aug 11. doi: 10.1016/j.ceca.2020.102264
PMCID:
PMC7530136
AbstractArticlePDF–3.0M
20.
Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology
Liam Argent, Friederike Winter, Imogen Prickett, Maria Carrasquero-Ordaz, Abby L. Olsen, Holger Kramer, Eric Lancaster, Esther B. E. Becker
J Biol Chem. 2020 Sep 4; 295(36): 12716–12726. Published online 2020 Jul 16. doi: 10.1074/jbc.RA120.012655
PMCID:
PMC7476715
AbstractArticlePDF–3.0M

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