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Items: 1 to 20 of 1408

1.
Interleukin-17 directly stimulates tumor infiltrating Tregs to prevent cancer development
William C. Theune, Ju Chen, Eileen Victoria Theune, Xiaoyang Ye, Antoine Ménoret, Anthony T. Vella, Kepeng Wang
Front Immunol. 2024; 15: 1408710. Published online 2024 Jun 14. doi: 10.3389/fimmu.2024.1408710
PMCID:
PMC11211274
AbstractArticlePDF–4.8M
2.
Loss of T follicular regulatory cell–derived IL-1R2 augments germinal center reactions via increased IL-1
Katerina Pyrillou, Melanie Humphry, Lauren A. Kitt, Amanda Rodgers, Meritxell Nus, Martin R. Bennett, Kenneth G.C. Smith, Paul A. Lyons, Ziad Mallat, Murray C.H. Clarke
JCI Insight. 2024 Mar 8; 9(5): e174005. Published online 2024 Feb 8. doi: 10.1172/jci.insight.174005
PMCID:
PMC11143922
AbstractArticlePDF–2.4M
3.
The role of microRNA-142a in Toxoplasma gondii infection-induced downregulation of Foxp3: implications for adverse pregnancy outcomes
Yue Zhong, Yining Cao, Xiaoyu Geng, Shujin Yang, Tianmei Qian, Chun Liu, Jinling Chen
BMC Infect Dis. 2024; 24: 490. Published online 2024 May 13. doi: 10.1186/s12879-024-09375-0
PMCID:
PMC11089769
AbstractArticlePDF–4.6M
4.
Selective deletion of Eos (Ikzf4) in T-regulatory cells leads to loss of suppressive function and development of systemic autoimmunity
Ameya S. Gokhale, Arunakumar Gangaplara, Maria Lopez-Occasio, Angela M. Thornton, Ethan M. Shevach
J Autoimmun. Author manuscript; available in PMC 2024 Apr 26.
Published in final edited form as: J Autoimmun. 2019 Dec; 105: 102300. Published online 2019 Jul 8. doi: 10.1016/j.jaut.2019.06.011
Correction in:
J Autoimmun. 2020 Sep 24 : 102544.
PMCID:
PMC11046398
AbstractArticlePDF–2.2M
5.
Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
Rajan M Thomas, Matthew C Pahl, Liqing Wang, Struan FA Grant, Wayne W Hancock, Andrew D Wells
eLife. 2024; 12: RP91392. Published online 2024 Apr 24. doi: 10.7554/eLife.91392
PMCID:
PMC11042806
AbstractArticlePDF–18M
6.
Prophylactic DNA vaccine targeting Foxp3+ regulatory T cells depletes myeloid-derived suppressor cells and improves anti-melanoma immune responses in a murine model
Afshin Namdar, Reza Mirzaei, Arash Memarnejadian, Roobina Boghosian, Morteza Samadi, Hamid Reza Mirzaei, Hamid Farajifard, Mehdi Zavar, Kayhan Azadmanesh, Shokrollah Elahi, Farshid Noorbakhsh, Abbas Rezaei, Jamshid Hadjati
Cancer Immunol Immunother. 2018 Mar; 67(3): 367–379. Published online 2017 Nov 9. doi: 10.1007/s00262-017-2088-6
PMCID:
PMC11028379
AbstractArticlePDF–2.9M
7.
Inhibition of Foxp3 expression in the placenta of mice infected intraperitoneally by toxoplasma gondii tachyzoites: insights into the PPARγ/miR-7b-5p/Sp1 signaling pathway
Yue Zhong, Cheng Qin, Qing Wang, Maoyuan Ding, Chong Qiu, Yunzhao Xu, Jinling Chen
Parasit Vectors. 2024; 17: 189. Published online 2024 Apr 17. doi: 10.1186/s13071-024-06262-0
PMCID:
PMC11025192
AbstractArticlePDF–5.4M
8.
Modulation of Treg cells/T effector function by GITR signaling is context–dependent
Amal Ephrem, Alan L. Epstein, Geoffrey L. Stephens, Angela M. Thornton, Deborah Glass, Ethan M. Shevach
Eur J Immunol. Author manuscript; available in PMC 2024 Apr 17.
Published in final edited form as: Eur J Immunol. 2013 Sep; 43(9): 2421–2429. Published online 2013 Jul 3. doi: 10.1002/eji.201343451
PMCID:
PMC11022273
AbstractArticlePDF–1010K
9.
Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice
Claire Soudais, Romane Schaus, Camille Bachelet, Norbert Minet, Sara Mouasni, Cécile Garcin, Caique Lopes Souza, Pierre David, Clara Cousu, Hélène Asnagli, Andrew Parker, Paul Palmquist-Gomes, Fernando E. Sepulveda, Sébastien Storck, Sigolène M. Meilhac, Alain Fischer, Emmanuel Martin, Sylvain Latour
Nat Commun. 2024; 15: 1982. Published online 2024 Mar 4. doi: 10.1038/s41467-024-45805-y
PMCID:
PMC10912214
AbstractArticlePDF–6.2M
10.
CD8+ T cell priming that is required for curative intratumorally anchored anti-4-1BB immunotherapy is constrained by Tregs
Joseph R. Palmeri, Brianna M. Lax, Joshua M. Peters, Lauren Duhamel, Jordan A. Stinson, Luciano Santollani, Emi A. Lutz, William Pinney, III, Bryan D. Bryson, K. Dane Wittrup
Nat Commun. 2024; 15: 1900. Published online 2024 Mar 1. doi: 10.1038/s41467-024-45625-0
PMCID:
PMC10907589
AbstractArticlePDF–3.3M
11.
Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity
Domnica Luca, Sumin Lee, Keiji Hirota, Yasutaka Okabe, Junji Uehori, Kazushi Izawa, Anna-Lisa Lanz, Verena Schütte, Burcu Sivri, Yuta Tsukamoto, Fabian Hauck, Rayk Behrendt, Axel Roers, Takashi Fujita, Ryuta Nishikomori, Min Ae Lee-Kirsch, Hiroki Kato
Sci Adv. 2024 Mar 1; 10(9): eadk0820. Published online 2024 Mar 1. doi: 10.1126/sciadv.adk0820
PMCID:
PMC10906915
AbstractArticlePDF–4.5M
12.
Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling
Joel Eggert, Wendy M. Zinzow-Kramer, Yuesong Hu, Elizabeth M. Kolawole, Yuan-Li Tsai, Arthur Weiss, Brian D. Evavold, Khalid Salaita, Christopher D. Scharer, Byron B. Au-Yeung
Sci Signal. Author manuscript; available in PMC 2024 Mar 6.
Published in final edited form as: Sci Signal. 2024 Feb 6; 17(822): eadh0439. Published online 2024 Feb 6. doi: 10.1126/scisignal.adh0439
PMCID:
PMC10897907
AbstractArticlePDF–2.0M
13.
Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
Hunter A. Martinez, Ievgen Koliesnik, Gernot Kaber, Jacqueline K. Reid, Nadine Nagy, Graham Barlow, Ben A. Falk, Carlos O. Medina, Aviv Hargil, Svenja Zihsler, Israel Vlodavsky, Jin-Ping Li, Magdiel Pérez-Cruz, Sai-Wen Tang, Everett H. Meyer, Lucile E. Wrenshall, James D. Lord, K. Christopher Garcia, Theo D. Palmer, Lawrence Steinman, Gerald T. Nepom, Thomas N. Wight, Paul L. Bollyky, Hedwich F. Kuipers
Nat Commun. 2024; 15: 1564. Published online 2024 Feb 20. doi: 10.1038/s41467-024-45012-9
PMCID:
PMC10879116
AbstractArticlePDF–3.7M
14.
Bob1 maintains T follicular helper cells for long-term humoral immunity
Masahiro Yanagi, Ippei Ikegami, Ryuta Kamekura, Tatsuya Sato, Taiki Sato, Shiori Kamiya, Kosuke Murayama, Sumito Jitsukawa, Fumie Ito, Akira Yorozu, Miho Kihara, Takaya Abe, Hiromi Takaki, Koji Kawata, Katsunori Shigehara, Satsuki Miyajima, Hirotaka Nishikiori, Akinori Sato, Noritsugu Tohse, Ken-ichi Takano, Hirofumi Chiba, Shingo Ichimiya
Commun Biol. 2024; 7: 185. Published online 2024 Feb 15. doi: 10.1038/s42003-024-05827-0
PMCID:
PMC10869348
AbstractArticlePDF–3.8M
15.
Chronic hypoxia disrupts T regulatory cell phenotype contributing to the emergence of exTreg-TH17 cells
Benjamin J. Lantz, Mika Moriwaki, Olufunmilola M. Oyebamiji, Yan Guo, Laura Gonzalez Bosc
Front Physiol. 2023; 14: 1304732. Published online 2024 Jan 29. doi: 10.3389/fphys.2023.1304732
PMCID:
PMC10859758
AbstractArticlePDF–2.5M
16.
Characterizing Foxp3+ and Foxp3- T cells in the homeostatic state and after allo-activation: resting CD4+Foxp3+ Tregs have molecular characteristics of activated T cells
Zilei Liu, Katherine J. Baines, Natalie M. Niessen, Munish K. Heer, David Clark, G. Alexander Bishop, Paul R. Trevillian
Front Immunol. 2024; 15: 1292158. Published online 2024 Jan 25. doi: 10.3389/fimmu.2024.1292158
PMCID:
PMC10850883
AbstractArticlePDF–7.6M
17.
Adipose-tissue regulatory T cells are a consortium of subtypes that evolves with age and diet
Andrés R. Muñoz-Rojas, Gang Wang, Christophe Benoist, Diane Mathis
Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4): e2320602121. Published online 2024 Jan 16. doi: 10.1073/pnas.2320602121
PMCID:
PMC10823167
AbstractArticlePDF–3.3M
18.
Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation
Tzu-Yu Shao, Tony T. Jiang, Joseph Stevens, Abigail E. Russi, Ty D. Troutman, Anas Bernieh, Giang Pham, John J. Erickson, Emily M. Eshleman, Theresa Alenghat, Stephen C. Jameson, Kristin A. Hogquist, Casey T. Weaver, David B. Haslam, Hitesh Deshmukh, Sing Sing Way
Cell Rep. Author manuscript; available in PMC 2024 Jan 28.
Published in final edited form as: Cell Rep. 2023 Nov 28; 42(11): 113323. Published online 2023 Oct 26. doi: 10.1016/j.celrep.2023.113323
PMCID:
PMC10822050
AbstractArticlePDF–2.5M
19.
A molecular signature for IL-10–producing Th1 cells in protozoan parasitic diseases
Chelsea L. Edwards, Jessica A. Engel, Fabian de Labastida Rivera, Susanna S. Ng, Dillon Corvino, Marcela Montes de Oca, Teija C.M. Frame, Shashi Bhushan Chauhan, Siddharth Sankar Singh, Awnish Kumar, Yulin Wang, Jinrui Na, Pam Mukhopadhyay, Jason S. Lee, Susanne Nylen, Shyam Sundar, Rajiv Kumar, Christian R. Engwerda
JCI Insight. 2023 Dec 22; 8(24): e169362. Published online 2023 Dec 22. doi: 10.1172/jci.insight.169362
PMCID:
PMC10807716
AbstractArticlePDF–1.3M
20.
IRF4 affects the protective effect of regulatory T cells on the pulmonary vasculature of a bronchopulmonary dysplasia mouse model by regulating FOXP3
Ying Zhu, Langyue He, Yue Zhu, Huici Yao, Jianfeng Jiang, Hongyan Lu
Mol Med. 2024; 30: 6. Published online 2024 Jan 9. doi: 10.1186/s10020-023-00770-y
PMCID:
PMC10777489
AbstractArticlePDF–3.2M

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