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Select item 114662821.

Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo

Juan Manuel Gomez, Hendrik Nolte, Elisabeth Vogelsang, Bipasha Dey, Michiko Takeda, Girolamo Giudice, Miriam Faxel, Theresa Haunold, Alina Cepraga, Robert P Zinzen, Marcus Krüger, Evangelia Petsalaki, Yu-Chiun Wang, Maria Leptin

eLife. 2024; 13: e99263. Published online 2024 Sep 2. doi: 10.7554/eLife.99263

PMCID:: PMC11466282

Abstract Article PDF–11M

Select item 112264912.

Highly conserved and extremely evolvable: BMP signalling in secondary axis patterning of Cnidaria and Bilateria

David Mörsdorf, Paul Knabl, Grigory Genikhovich

Dev Genes Evol. 2024; 234(1): 1–19. Published online 2024 Mar 13. doi: 10.1007/s00427-024-00714-4

PMCID:: PMC11226491

Abstract Article PDF–4.1M

Select item 111670003.

Molecular mechanism of BMP signal control by Twisted gastrulation

Tomas Malinauskas, Gareth Moore, Amalie F. Rudolf, Holly Eggington, Hayley L. Belnoue-Davis, Kamel El Omari, Samuel C. Griffiths, Rachel E. Woolley, Ramona Duman, Armin Wagner, Simon J. Leedham, Clair Baldock, Hilary L. Ashe, Christian Siebold

Nat Commun. 2024; 15: 4976. Published online 2024 Jun 11. doi: 10.1038/s41467-024-49065-8

PMCID:: PMC11167000

Abstract Article PDF–3.7M

Select item 111469684.

Regulation of BMP/Dpp signaling during embryonic development

T. Nakayama*, Y. Cui*, J. L. Christian**

Cell Mol Life Sci. 2000 Jun; 57(6): 943–956. doi: 10.1007/PL00000736

PMCID:: PMC11146968

Abstract Article PDF–541K

Select item 108477255.

Bone morphogenetic protein signaling: the pathway and its regulation

Takuya Akiyama, Laurel A Raftery, Kristi A Wharton

Genetics. 2024 Feb; 226(2): iyad200. Published online 2023 Dec 20. doi: 10.1093/genetics/iyad200

PMCID:: PMC10847725

Abstract Article PDF–6.8M

Select item 108423166.

Regulation of the dynamic RNA Pol II elongation rate in Drosophila embryos

Samuel H. Keller, Hao Deng, Bomyi Lim

Cell Rep. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113225. Published online 2023 Oct 12. doi: 10.1016/j.celrep.2023.113225

PMCID:: PMC10842316

Abstract Article PDF–1.6M

Select item 107633637.

Tissue-specific RNA Polymerase II promoter-proximal pause release and burst kinetics in a Drosophila embryonic patterning network

George Hunt, Roshan Vaid, Sergei Pirogov, Alexander Pfab, Christoph Ziegenhain, Rickard Sandberg, Johan Reimegård, Mattias Mannervik

Genome Biol. 2024; 25: 2. Published online 2024 Jan 2. doi: 10.1186/s13059-023-03135-0

PMCID:: PMC10763363

Abstract Article PDF–9.8M

Select item 107044878.

Single-cell transcriptomics illuminates regulatory steps driving anterior-posterior patterning of Drosophila embryonic mesoderm

Jingjing Sun, Chen Zhang, Fan Gao, Angelike Stathopoulos

Cell Rep. Author manuscript; available in PMC 2023 Dec 8.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113289. Published online 2023 Oct 19. doi: 10.1016/j.celrep.2023.113289

PMCID:: PMC10704487

Abstract Article PDF–2.8M

Select item 107027979.

Convergent insulin and TGF‐β signalling drives cancer cachexia by promoting aberrant fat body ECM accumulation in a Drosophila tumour model

Daniel Bakopoulos, Sofya Golenkina, Callum Dark, Elizabeth L Christie, Besaiz J Sánchez‐Sánchez, Brian M Stramer, Louise Y Cheng

EMBO Rep. 2023 Dec; 24(12): e57695. Published online 2023 Nov 28. doi: 10.15252/embr.202357695

PMCID:: PMC10702797

Abstract Article PDF–14M

Select item 1060910710.

The Sterol Transporter Npc2c Controls Intestinal Stem Cell Mitosis and Host–Microbiome Interactions in Drosophila

Constantina Neophytou, Euripides Soteriou, Chrysoula Pitsouli

Metabolites. 2023 Oct; 13(10): 1084. Published online 2023 Oct 16. doi: 10.3390/metabo13101084

PMCID:: PMC10609107

Abstract Article PDF–8.3M

Select item 1059220311.

Chromatin accessibility in the Drosophila embryo is determined by transcription factor pioneering and enhancer activation

Kaelan J. Brennan, Melanie Weilert, Sabrina Krueger, Anusri Pampari, Hsiao-yun Liu, Ally W.H. Yang, Jason A. Morrison, Timothy R. Hughes, Christine A. Rushlow, Anshul Kundaje, Julia Zeitlinger

Dev Cell. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Dev Cell. 2023 Oct 9; 58(19): 1898–1916.e9. Published online 2023 Aug 8. doi: 10.1016/j.devcel.2023.07.007

PMCID:: PMC10592203

Abstract Article PDF–3.4M

Select item 1044573012.

Separation of transcriptional repressor and activator functions in Drosophila HDAC3

Min Tang, Isabel Regadas, Sergey Belikov, Olga Shilkova, Lei Xu, Erik Wernersson, Xuewen Liu, Hongmei Wu, Magda Bienko, Mattias Mannervik

Development. 2023 Aug 1; 150(15): dev201548. Published online 2023 Aug 2. doi: 10.1242/dev.201548

PMCID:: PMC10445730

Abstract Article

Select item 1033794813.

Reconstitution of morphogen shuttling circuits

Ronghui Zhu, Leah A. Santat, Joseph S. Markson, Nagarajan Nandagopal, Jan Gregrowicz, Michael B. Elowitz

Sci Adv. 2023 Jul; 9(28): eadf9336. Published online 2023 Jul 12. doi: 10.1126/sciadv.adf9336

PMCID:: PMC10337948

Abstract Article PDF–2.5M

Select item 1028315914.

Modulation of transcription burst amplitude underpins dosage compensation in the Drosophila embryo

Lauren Forbes Beadle, Hongpeng Zhou, Magnus Rattray, Hilary L. Ashe

Cell Rep. 2023 Apr 25; 42(4): 112382. Published online 2023 Apr 14. doi: 10.1016/j.celrep.2023.112382

PMCID:: PMC10283159

Abstract Article

Select item 968706315.

Shadow enhancers modulate distinct transcriptional parameters that differentially effect downstream patterning events

Peter H. Whitney, Bikhyat Shrestha, Jiahan Xiong, Tom Zhang, Christine A. Rushlow

Development. 2022 Nov 1; 149(21): dev200940. Published online 2022 Nov 1. doi: 10.1242/dev.200940

PMCID:: PMC9687063

Abstract Article

Select item 966833416.

Genetic architecture of natural variation of cardiac performance from flies to humans

Saswati Saha, Lionel Spinelli, Jaime A Castro Mondragon, Anaïs Kervadec, Michaela Lynott, Laurent Kremmer, Laurence Roder, Sallouha Krifa, Magali Torres, Christine Brun, Georg Vogler, Rolf Bodmer, Alexandre R Colas, Karen Ocorr, Laurent Perrin

eLife. 2022; 11: e82459. Published online 2022 Nov 16. doi: 10.7554/eLife.82459