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Select item 104880761.

A Comparison of PKD2L1-Expressing Cerebrospinal Fluid Contacting Neurons in Spinal Cords of Rodents, Carnivores, and Primates

Xiaohe Liu, Karen Rich, Sohail M. Nasseri, Guifa Li, Simone Hjæresen, Bente Finsen, Hansjörg Scherberger, Åsa Svenningsen, Mengliang Zhang

Int J Mol Sci. 2023 Sep; 24(17): 13582. Published online 2023 Sep 1. doi: 10.3390/ijms241713582

PMCID:: PMC10488076

Abstract Article PDF–12M

Select item 102359932.

Primary cilia TRP channel regulates hippocampal excitability

Thuy N. Vien, My C. Ta, Louise F. Kimura, Tuncer Onay, Paul G. DeCaen

Proc Natl Acad Sci U S A. 2023 May 30; 120(22): e2219686120. Published online 2023 May 22. doi: 10.1073/pnas.2219686120

PMCID:: PMC10235993

Abstract Article PDF–7.0M

Select item 101914413.

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji

Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888

PMCID:: PMC10191441

Abstract Article PDF–2.4M

Select item 101315604.

A Transcription Factor Etv1/Er81 Is Involved in the Differentiation of Sweet, Umami, and Sodium Taste Cells

Makoto Ohmoto, Masafumi Jyotaki, Karen K. Yee, Ichiro Matsumoto

eNeuro. 2023 Apr; 10(4): ENEURO.0236-22.2023. Prepublished online 2023 Apr 12. Published online 2023 Apr 21. doi: 10.1523/ENEURO.0236-22.2023

PMCID:: PMC10131560

Abstract Article PDF–6.9M

Select item 100178215.

Polycystic kidney disease 2-like 1 channel contributes to the bitter aftertaste perception of quinine

Takahiro Shimizu, Takuto Fujii, Keisuke Hanita, Ryo Shinozaki, Yusaku Takamura, Yoshiro Suzuki, Teppei Kageyama, Mizuki Kato, Hisao Nishijo, Makoto Tominaga, Hideki Sakai

Sci Rep. 2023; 13: 4271. Published online 2023 Mar 15. doi: 10.1038/s41598-023-31322-3

PMCID:: PMC10017821

Abstract Article PDF–4.1M

Select item 96168006.

DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential

Bruno Frederico, Isaura Martins, Diana Chapela, Francesca Gasparrini, Probir Chakravarty, Tobias Ackels, Cécile Piot, Bruna Almeida, Joana Carvalho, Alessandro Ciccarelli, Christopher J. Peddie, Neil Rogers, James Briscoe, François Guillemot, Andreas T. Schaefer, Leonor Saúde, Caetano Reis e Sousa

Dev Cell. 2022 Aug 22; 57(16): 1957–1975.e9. doi: 10.1016/j.devcel.2022.07.012

PMCID:: PMC9616800

Abstract Article

Select item 87752497.

Enhanced β-adrenergic response in mice with dominant-negative expression of the PKD2L1 channel

Manabu Murakami, Agnieszka M. Murakami, Takayuki Nemoto, Takayoshi Ohba, Manabu Yonekura, Yuichi Toyama, Hirofumi Tomita, Yasushi Matsuzaki, Daisuke Sawamura, Kazuyoshi Hirota, Shirou Itagaki, Yujiro Asada, Ichiro Miyoshi

PLoS One. 2022; 17(1): e0261668. Published online 2022 Jan 20. doi: 10.1371/journal.pone.0261668

PMCID:: PMC8775249

Abstract Article PDF–1.4M

Select item 67852678.

Taste bud formation depends on taste nerves

Di Fan, Zoubida Chettouh, G Giacomo Consalez, Jean-François Brunet

eLife. 2019; 8: e49226. Published online 2019 Oct 1. doi: 10.7554/eLife.49226

PMCID:: PMC6785267

Abstract Article PDF–4.8M

Select item 65206439.

Physiological and Behavioral Responses to Optogenetic Stimulation of PKD2L1⁺ Type III Taste Cells

Courtney E. Wilson, Aurelie Vandenbeuch, Sue C. Kinnamon

eNeuro. 2019 Mar-Apr; 6(2): ENEURO.0107-19.2019. Prepublished online 2019 Apr 25. Published online 2019 May 9. doi: 10.1523/ENEURO.0107-19.2019

PMCID:: PMC6520643

Abstract Article PDF–2.1M

Select item 586475410.

Cryo-EM structure of the polycystic kidney disease-like channel PKD2L1

Qiang Su, Feizhuo Hu, Yuxia Liu, Xiaofei Ge, Changlin Mei, Shengqiang Yu, Aiwen Shen, Qiang Zhou, Chuangye Yan, Jianlin Lei, Yanqing Zhang, Xiaodong Liu, Tingliang Wang

Nat Commun. 2018; 9: 1192. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03606-0

PMCID:: PMC5864754

Abstract Article PDF–2.5M

Select item 558639711.

The asparagine 533 residue in the outer pore loop region of the mouse PKD2L1 channel is essential for its voltage‐dependent inactivation

Takahiro Shimizu, Taiga Higuchi, Toshihiro Toba, Chie Ohno, Takuto Fujii, Bernd Nilius, Hideki Sakai

FEBS Open Bio. 2017 Sep; 7(9): 1392–1401. Published online 2017 Aug 14. doi: 10.1002/2211-5463.12273

PMCID:: PMC5586397

Abstract Article PDF–1.0M

Select item 545117112.

The familial dysautonomia disease gene IKBKAP is required in the developing and adult mouse central nervous system

Marta Chaverra, Lynn George, Marc Mergy, Hannah Waller, Katharine Kujawa, Connor Murnion, Ezekiel Sharples, Julian Thorne, Nathaniel Podgajny, Andrea Grindeland, Yumi Ueki, Steven Eiger, Cassie Cusick, A. Michael Babcock, George A. Carlson, Frances Lefcort

Dis Model Mech. 2017 May 1; 10(5): 605–618. doi: 10.1242/dmm.028258

PMCID:: PMC5451171

Abstract Article

Select item 481333713.

The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord

Yanina L. Petracca, Maria Micaela Sartoretti, Daniela J. Di Bella, Antonia Marin-Burgin, Abel L. Carcagno, Alejandro F. Schinder, Guillermo M. Lanuza

Development. 2016 Mar 1; 143(5): 880–891. doi: 10.1242/dev.129254

PMCID:: PMC4813337

Abstract Article

Select item 476392014.

A proton current associated with sour taste: distribution and functional properties

Jeremy D. Bushman, Wenlei Ye, Emily R. Liman

FASEB J. 2015 Jul; 29(7): 3014–3026. Published online 2015 Apr 9. doi: 10.1096/fj.14-265694

PMCID:: PMC4763920

Abstract Article

Select item 473101915.

Disruption of polycystin-L causes hippocampal and thalamocortical hyperexcitability

Gang Yao, Chong Luo, Michael Harvey, Maoqing Wu, Taylor H. Schreiber, Yanjun Du, Nuria Basora, Xuefeng Su, Diego Contreras, Jing Zhou

Hum Mol Genet. 2016 Feb 1; 25(3): 448–458. Published online 2015 Nov 26. doi: 10.1093/hmg/ddv484

PMCID:: PMC4731019

Abstract Article PDF–1.0M

Select item 472031916.

The K⁺ channel K_IR2.1 functions in tandem with proton influx to mediate sour taste transduction

Wenlei Ye, Rui B. Chang, Jeremy D. Bushman, Yu-Hsiang Tu, Eric M. Mulhall, Courtney E. Wilson, Alexander J. Cooper, Wallace S. Chick, David C. Hill-Eubanks, Mark T. Nelson, Sue C. Kinnamon, Emily R. Liman

Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2): E229–E238. Published online 2015 Dec 1. doi: 10.1073/pnas.1514282112

PMCID:: PMC4720319

Abstract Article PDF–3.8M

Select item 417816217.

Genetic dissection of TrkB activated signalling pathways required for specific aspects of the taste system

Juraj Koudelka, Jacqueline M Horn, Chinnavuth Vatanashevanopakorn, Liliana Minichiello

Neural Dev. 2014; 9: 21. Published online 2014 Sep 26. doi: 10.1186/1749-8104-9-21

PMCID:: PMC4178162

Abstract Article PDF–3.0M

Select item 411273718.

Primary cilia are specialized calcium signaling organelles

Markus Delling, Paul G. DeCaen, Julia F. Doerner, Sebastien Febvay, David E. Clapham

Nature. Author manuscript; available in PMC 2014 Jul 28.

Published in final edited form as: Nature. 2013 Dec 12; 504(7479): 311–314. doi: 10.1038/nature12833

PMCID:: PMC4112737

Abstract Article PDF–4.3M

Select item 407364619.

Direct recording and molecular identification of the calcium channel of primary cilia

Paul G. DeCaen, Markus Delling, Thuy N. Vien, David E. Clapham

Nature. Author manuscript; available in PMC 2014 Jun 27.

Published in final edited form as: Nature. 2013 Dec 12; 504(7479): 315–318. doi: 10.1038/nature12832

Correction in:: volume 513 on page 266

PMCID:: PMC4073646

Abstract Article PDF–2.2M

Select item 357241020.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163