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Select item 115390451.

Intestinal ILC3s Migrate to the Kidney and Promote Renal Fibrosis via PD-1-mediated Activation

Zhou Liang, Ziwen Tang, Changjian Zhu, Feng Li, Shuaijiabin Chen, Xu Han, Ruilin Zheng, Xinrong Hu, Ruoni Lin, Qiaoqiao Pei, Changjun Yin, Ji Wang, Ce Tang, Nan Cao, Jincun Zhao, Rong Wang, Xiaoyan Li, Ning Luo, Qiong Wen, Jianwen Yu, Jianbo Li, Xi Xia, Xunhua Zheng, Xin Wang, Naya Huang, Zhong Zhong, Chengqiang Mo, Peisong Chen, Yating Wang, Jinjin Fan, Yun Guo, Haojie Zhong, Jiaqi Liu, Zhenwei Peng, Haiping Mao, Guo-Ping Shi, Joseph V. Bonventre, Wei Chen, Yi Zhou

Immunity. Author manuscript; available in PMC 2024 Nov 6.

Published in final edited form as: Immunity. 2024 Jun 11; 57(6): 1306–1323.e8. Published online 2024 May 29. doi: 10.1016/j.immuni.2024.05.004

PMCID:: PMC11539045

Abstract Article PDF–4.5M

Select item 115152682.

High PD-1 and CTLA-4 expression correlates with host immune suppression in patients and a mouse model infected with Echinococcus multilocularis

Ting Sun, Yi Yang, Yiwen Qiu, Tao Wang, Ming Yang, Shu Shen, Wentao Wang

Parasit Vectors. 2024; 17: 437. Published online 2024 Oct 25. doi: 10.1186/s13071-024-06511-2

PMCID:: PMC11515268

Abstract Article PDF–3.6M

Select item 114674123.

FBXO38 is dispensable for PD-1 regulation

Nikol Dibus, Eva Salyova, Karolina Kolarova, Alikhan Abdirov, Michele Pagano, Ondrej Stepanek, Lukas Cermak

EMBO Rep. 2024 Oct; 25(10): 4206–4225. Published online 2024 Sep 12. doi: 10.1038/s44319-024-00220-8

PMCID:: PMC11467412

Abstract Article PDF–3.1M

Select item 114467094.

Roles of programmed death‐1 and muscle innate lymphoid cell‐derived interleukin 13 in sepsis‐induced intensive care unit‐acquired weakness

Yuichi Akama, Eun Jeong Park, Naoko Satoh‐Takayama, Atsushi Ito, Eiji Kawamoto, Arong Gaowa, Eri Matsuo, Satoshi Oikawa, Masafumi Saito, Shigeaki Inoue, Takayuki Akimoto, Kei Suzuki, Motomu Shimaoka

J Cachexia Sarcopenia Muscle. 2024 Oct; 15(5): 1999–2012. Published online 2024 Jul 17. doi: 10.1002/jcsm.13548

PMCID:: PMC11446709

Abstract Article PDF–1.7M

Select item 113555685.

Determinants of pegivirus persistence, cross-species infection, and adaptation in the laboratory mouse

Kylie Nennig, Satyapramod Murthy, Sara Maloney, Teressa M. Shaw, Mark Sharobim, Eduard Matkovic, Simi Fadiran, Malorie Larsen, Mitchell D. Ramuta, Arthur S. Kim, John R. Teijaro, Joe Grove, Matthew Stremlau, Himanshu Sharma, Sheetal Trivedi, Michael J. Blum, David H. O’Connor, Jennifer L. Hyde, Jack T. Stapleton, Amit Kapoor, Adam L. Bailey

PLoS Pathog. 2024 Aug; 20(8): e1012436. Published online 2024 Aug 28. doi: 10.1371/journal.ppat.1012436

PMCID:: PMC11355568

Abstract Article PDF–4.3M

Select item 113238306.

Expansion of Pathogenic Cardiac Macrophages in Immune Checkpoint Inhibitor Myocarditis

Pan Ma, Jing Liu, Juan Qin, Lulu Lai, Gyu Seong Heo, Hannah Luehmann, Deborah Sultan, Andrea Bredemeyer, Geetika Bajapa, Guoshuai Feng, Jesus Jimenez, Ruijun He, Antanisha Parks, Junedh Amrute, Ana Villanueva, Yongjian Liu, Chieh-Yu Lin, Matthias Mack, Kaushik Amancherla, Javid Moslehi, Kory J. Lavine

Circulation. Author manuscript; available in PMC 2024 Aug 14.

Published in final edited form as: Circulation. 2024 Jan 2; 149(1): 48–66. Published online 2023 Sep 25. doi: 10.1161/CIRCULATIONAHA.122.062551

PMCID:: PMC11323830

Abstract Article PDF–4.7M

Select item 112909777.

Androgen aggravates aortic aneurysms via suppression of PD-1 in mice

Xufang Mu, Shu Liu, Zhuoran Wang, Kai Jiang, Tim McClintock, Arnold J. Stromberg, Alejandro V. Tezanos, Eugene S. Lee, John A. Curci, Ming C. Gong, Zhenheng Guo

J Clin Invest. 2024 Aug 1; 134(15): e169085. Published online 2024 Jun 20. doi: 10.1172/JCI169085

PMCID:: PMC11290977

Abstract Article PDF–4.4M

Select item 112208288.

Soluble PD-L1 reprograms blood monocytes to prevent cerebral edema and facilitate recovery after ischemic stroke

Jennifer E. Kim, Ryan P. Lee, Eli Yazigi, Lyla Atta, James Feghali, Ayush Pant, Aanchal Jain, Idan Levitan, Eileen Kim, Kisha Patel, Nivedha Kannapadi, Pavan Shah, Adnan Bibic, Zhipeng Hou, Justin M. Caplan, L. Fernando Gonzalez, Judy Huang, Risheng Xu, Jean Fan, Betty Tyler, Henry Brem, Vassiliki A. Boussiotis, Lauren Jantzie, Shenandoah Robinson, Raymond C. Koehler, Michael Lim, Rafael J. Tamargo, Christopher M. Jackson

Brain Behav Immun. Author manuscript; available in PMC 2024 Jul 3.

Published in final edited form as: Brain Behav Immun. 2024 Feb; 116: 160–174. Published online 2023 Dec 7. doi: 10.1016/j.bbi.2023.12.007

PMCID:: PMC11220828

Abstract Article PDF–2.1M

Select item 111805979.

PD-1 signaling in neonates restrains CD8⁺ T cell function and protects against respiratory viral immunopathology

Taylor Eddens, Olivia B. Parks, Yu Zhang, Michelle L. Manni, Jean-Laurent Casanova, Masato Ogishi, John V. Williams

Mucosal Immunol. Author manuscript; available in PMC 2024 Jun 17.

Published in final edited form as: Mucosal Immunol. 2024 Jun; 17(3): 476–490. Published online 2024 Jan 3. doi: 10.1016/j.mucimm.2023.12.004

PMCID:: PMC11180597

Abstract Article PDF–2.1M

Select item 1108911310.

PD-1 knockout on cytotoxic primary murine CD8⁺ T cells improves their motility in retrovirus infected mice

Daniela Mittermüller, Lucas Otto, Annika Loredana Kilian, Ann-Kathrin Schnormeier, Elisabeth Littwitz-Salomon, Anja Hasenberg, Ulf Dittmer, Matthias Gunzer

Front Immunol. 2024; 15: 1338218. Published online 2024 Apr 29. doi: 10.3389/fimmu.2024.1338218

PMCID:: PMC11089113

Abstract Article PDF–1.2M

Select item 1103093911.

Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells

Yu Liu, Yinyan Yu, Suguang Yang, Bin Zeng, Zhuohan Zhang, Guohui Jiao, Yuan Zhang, Limin Cai, Rongcun Yang

Cancer Immunol Immunother. 2009 May; 58(5): 687–697. Published online 2008 Oct 1. doi: 10.1007/s00262-008-0591-5

PMCID:: PMC11030939

Abstract Article PDF–581K

Select item 1102772212.

Anti-angiogenesis therapy overcomes the innate resistance to PD-1/PD-L1 blockade in VEGFA-overexpressed mouse tumor models

Qiaohong Wang, Jingze Gao, Wen Di, Xia Wu

Cancer Immunol Immunother. 2020 Sep; 69(9): 1781–1799. Published online 2020 Apr 28. doi: 10.1007/s00262-020-02576-x

PMCID:: PMC11027722

Abstract Article PDF–17M

Select item 1102761913.

Peri-tumor administration of controlled release anti-CTLA-4 synergizes with systemic anti-PD-1 to induce systemic antitumor immunity while sparing autoimmune toxicity

Airi Harui, Sandra M. McLachlan, Basil Rapoport, Thomas I. Zarembinski, Michael D. Roth

Cancer Immunol Immunother. 2020 Sep; 69(9): 1737–1749. Published online 2020 Apr 24. doi: 10.1007/s00262-020-02579-8

PMCID:: PMC11027619

Abstract Article PDF–878K

Select item 1098918914.

PD-1 maintains CD8 T cell tolerance towards cutaneous neoantigens

Martina Damo, Noah I. Hornick, Aarthi Venkat, Ivana William, Kathryn Clulo, Srividhya Venkatesan, Jiaming He, Eric Fagerberg, Jennifer L. Loza, Darwin Kwok, Aya Tal, Jessica Buck, Can Cui, Jaiveer Singh, William E. Damsky, Jonathan S. Leventhal, Smita Krishnaswamy, Nikhil S. Joshi

Nature. Author manuscript; available in PMC 2024 Apr 3.

Published in final edited form as: Nature. 2023 Jul; 619(7968): 151–159. Published online 2023 Jun 21. doi: 10.1038/s41586-023-06217-y