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Select item 109427711.

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

Chloé Mayère, Violaine Regard, Aitana Perea-Gomez, Corey Bunce, Yasmine Neirijnck, Cyril Djari, Natividad Bellido-Carreras, Pauline Sararols, Richard Reeves, Simon Greenaway, Michelle Simon, Pam Siggers, Diana Condrea, Françoise Kühne, Ivana Gantar, Furong Tang, Isabelle Stévant, Laura Batti, Norbert B. Ghyselinck, Dagmar Wilhelm, Andy Greenfield, Blanche Capel, Marie-Christine Chaboissier, Serge Nef

Sci Adv. 2022 May; 8(21): eabm0972. Published online 2022 May 25. doi: 10.1126/sciadv.abm0972

PMCID:: PMC10942771

Abstract Article PDF–6.7M

Select item 105454372.

DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons

Arquimedes Cheffer, Marta Garcia-Miralles, Esther Maier, Ipek Akol, Henriette Franz, Vandana Shree Vedartham Srinivasan, Tanja Vogel

Cereb Cortex. 2023 Oct 1; 33(19): 10272–10285. Published online 2023 Aug 11. doi: 10.1093/cercor/bhad281

PMCID:: PMC10545437

Abstract Article PDF–2.8M

Select item 104824293.

Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation

Wilma Tixi, Maricela Maldonado, Ya-Ting Chang, Amy Chiu, Wilson Yeung, Nazia Parveen, Michael S Nelson, Ryan Hart, Shihao Wang, Wu Jih Hsu, Patrick Fueger, Janel L Kopp, Mark O Huising, Sangeeta Dhawan, Hung Ping Shih

eLife. 2023; 12: e90006. Published online 2023 Aug 23. doi: 10.7554/eLife.90006

PMCID:: PMC10482429

Abstract Article PDF–26M

Select item 103931934.

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain

Vladimir Abarinov, Joshua A. Levine, Angela J. Churchill, Bryce Hopwood, Cailin S. Deiter, Michelle A. Guney, Kristen L. Wells, Jessica M. Schrunk, Yuchun Guo, Jennifer Hammelman, David K. Gifford, Mark A. Magnuson, Hynek Wichterle, Lori Sussel

Genes Dev. 2023 Jun 1; 37(11-12): 490–504. doi: 10.1101/gad.350569.123

PMCID:: PMC10393193

Abstract Article PDF–22M

Select item 103904925.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 102815496.

Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs

Sara J. Knowles, April M. Stafford, Tariq Zaman, Kartik Angara, Michael R. Williams, Jason M. Newbern, Daniel Vogt

Development. 2023 May 15; 150(10): dev201371. Published online 2023 May 31. doi: 10.1242/dev.201371

PMCID:: PMC10281549

Abstract Article

Select item 100177037.

Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions

Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco

Nat Commun. 2023; 14: 1439. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37199-0

PMCID:: PMC10017703

Abstract Article PDF–16M

Select item 99995288.

ISL1 controls pancreatic alpha cell fate and beta cell maturation

Romana Bohuslavova, Valeria Fabriciova, Laura Lebrón-Mora, Jessica Malfatti, Ondrej Smolik, Lukas Valihrach, Sarka Benesova, Daniel Zucha, Zuzana Berkova, Frantisek Saudek, Sylvia M Evans, Gabriela Pavlinkova

Cell Biosci. 2023; 13: 53. Published online 2023 Mar 10. doi: 10.1186/s13578-023-01003-9

PMCID:: PMC9999528

Abstract Article PDF–7.7M

Select item 97754899.

Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models

Hamid Meziane, Marie-Christine Birling, Olivia Wendling, Sophie Leblanc, Aline Dubos, Mohammed Selloum, Guillaume Pavlovic, Tania Sorg, Vera M. Kalscheuer, Pierre Billuart, Frédéric Laumonnier, Jamel Chelly, Hans van Bokhoven, Yann Herault

Biomedicines. 2022 Dec; 10(12): 3148. Published online 2022 Dec 6. doi: 10.3390/biomedicines10123148

PMCID:: PMC9775489

Abstract Article PDF–2.8M

Select item 957569610.

Bmi1 suppresses protein synthesis and promotes proteostasis in hematopoietic stem cells

Rebecca J. Burgess, Zhiyu Zhao, Daisuke Nakada, Sean J. Morrison

Genes Dev. 2022 Aug 1; 36(15-16): 887–900. doi: 10.1101/gad.349917.122

PMCID:: PMC9575696

Abstract Article PDF–2.7M

Select item 933333611.

Generation of FLAG-tagged Arx knock-in mouse model

Youngshin Lim, Il-Taeg Cho, Jeffrey A. Golden, Ginam Cho

Genesis. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Genesis. 2022 Jul; 60(6-7): e23479. Published online 2022 Jun 3. doi: 10.1002/dvg.23479

PMCID:: PMC9333336

Abstract Article PDF–1.9M

Select item 916945912.

Deregulation of microtubule organization and RNA metabolism in Arx models for lissencephaly and developmental epileptic encephalopathy

Denise Drongitis, Marianna Caterino, Lucia Verrillo, Pamela Santonicola, Michele Costanzo, Loredana Poeta, Benedetta Attianese, Adriano Barra, Gaetano Terrone, Maria Brigida Lioi, Simona Paladino, Elia Di Schiavi, Valerio Costa, Margherita Ruoppolo, Maria Giuseppina Miano

Hum Mol Genet. 2022 Jun 1; 31(11): 1884–1908. Published online 2022 Jan 31. doi: 10.1093/hmg/ddac028

PMCID:: PMC9169459

Abstract Article PDF–3.6M

Select item 835316213.

Single-cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human-specific features

Teresa Rayon, Rory J. Maizels, Christopher Barrington, James Briscoe

Development. 2021 Aug 1; 148(15): dev199711. Published online 2021 Aug 5. doi: 10.1242/dev.199711

PMCID:: PMC8353162

Abstract Article

Select item 831323914.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 826883715.

NEUROD1 Is Required for the Early α and β Endocrine Differentiation in the Pancreas

Romana Bohuslavova, Ondrej Smolik, Jessica Malfatti, Zuzana Berkova, Zaneta Novakova, Frantisek Saudek, Gabriela Pavlinkova

Int J Mol Sci. 2021 Jul; 22(13): 6713. Published online 2021 Jun 23. doi: 10.3390/ijms22136713

PMCID:: PMC8268837

Abstract Article PDF–4.9M

Select item 826556616.

The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain

Maria Elena Martinez, Arturo Hernandez

Front Neurosci. 2021; 15: 703730. Published online 2021 Jun 29. doi: 10.3389/fnins.2021.703730

PMCID:: PMC8265566

Abstract Article PDF–8.3M

Select item 825156217.

Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease

Evans Quilichini, Mélanie Fabre, Christoffer Nord, Thassadite Dirami, Axelle Le Marec, Silvia Cereghini, Raymond C Pasek, Maureen Gannon, Ulf Ahlgren, Cécile Haumaitre

J Pathol. 2021 May; 254(1): 31–45. Published online 2021 Mar 18. doi: 10.1002/path.5629

PMCID:: PMC8251562

Abstract Article PDF–46M

Select item 803897218.

Ultraconserved Enhancer Function Does Not Require Perfect Sequence Conservation

Valentina Snetkova, Athena R. Ypsilanti, Jennifer A. Akiyama, Brandon J. Mannion, Ingrid Plajzer-Frick, Catherine S. Novak, Anne N. Harrington, Quan T. Pham, Momoe Kato, Yiwen Zhu, Janeth Godoy, Eman Meky, Riana D. Hunter, Marie Shi, Evgeny Z. Kvon, Veena Afzal, Stella Tran, John L.R. Rubenstein, Axel Visel, Len A. Pennacchio, Diane E. Dickel

Nat Genet. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Nat Genet. 2021 Apr; 53(4): 521–528. Published online 2021 Mar 29. doi: 10.1038/s41588-021-00812-3

PMCID:: PMC8038972

Abstract Article PDF–6.1M

Select item 801525319.

A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development

Anna B. Osipovich, Karrie D. Dudek, Emily Greenfest-Allen, Jean-Philippe Cartailler, Elisabetta Manduchi, Leah Potter Case, Eunyoung Choi, Austin G. Chapman, Hannah W. Clayton, Guoqiang Gu, Christian J. Stoeckert, Jr, Mark A. Magnuson

Development. 2021 Mar 15; 148(6): dev196964. Published online 2021 Mar 22. doi: 10.1242/dev.196964

PMCID:: PMC8015253

Abstract Article

Select item 780716320.

Postnatal Arx transcriptional activity regulates functional properties of PV interneurons

Donald J. Joseph, Markus Von Deimling, Yuiko Hasegawa, Ana G. Cristancho, Rebecca C. Ahrens-Nicklas, Stephanie L. Rogers, Rashmi Risbud, Almedia J. McCoy, Eric D. Marsh

iScience. 2021 Jan 22; 24(1): 101999. Published online 2020 Dec 28. doi: 10.1016/j.isci.2020.101999

PMCID:: PMC7807163

Abstract Article PDF–5.8M

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