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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108667032.

Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture

Clémentine Villeneuve, Ali Hashmi, Irene Ylivinkka, Elizabeth Lawson-Keister, Yekaterina A. Miroshnikova, Carlos Pérez-González, Satu-Marja Myllymäki, Fabien Bertillot, Bhagwan Yadav, Tao Zhang, Danijela Matic Vignjevic, Marja L. Mikkola, M. Lisa Manning, Sara A. Wickström

Nat Cell Biol. 2024; 26(2): 207–218. Published online 2024 Feb 1. doi: 10.1038/s41556-023-01332-4

PMCID:: PMC10866703

Abstract Article PDF–10M

Select item 105171713.

Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte

Zhiqin Fang, Yutong Wang, Bo Huang, Xiang Chen, Rundong Jiang, Mingzhu Yin

Cell Death Dis. 2023 Sep; 14(9): 627. Published online 2023 Sep 22. doi: 10.1038/s41419-023-06134-y

PMCID:: PMC10517171

Abstract Article PDF–9.7M

Select item 103632394.

Ectodysplasin signaling via Xedar is required for mammary gland morphogenesis

Abigail R. Wark, Daniel Aldea, Reiko R. Tomizawa, Blerina Kokalari, Bailey Warder, Yana G. Kamberov

J Invest Dermatol. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: J Invest Dermatol. 2023 Aug; 143(8): 1529–1537.e2. Published online 2023 Feb 18. doi: 10.1016/j.jid.2023.02.007

PMCID:: PMC10363239

Abstract Article PDF–1.0M

Select item 90106275.

A Foxo1-Klf2-S1pr1-Gnai1-Rac1 signaling axis is a critical mediator of Ostm1 regulatory network in T lymphopoiesis

Marie S. Mutabaruka, Monica Pata, Jean Vacher

iScience. 2022 Apr 15; 25(4): 104160. Published online 2022 Mar 25. doi: 10.1016/j.isci.2022.104160

PMCID:: PMC9010627

Abstract Article PDF–5.7M

Select item 89909266.

The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa

Jorge del-Pozo, Denis J. Headon, James D. Glover, Ali Azar, Sonia Schuepbach-Mallepell, Mahmood F. Bhutta, Jon Riddell, Scott Maxwell, Elspeth Milne, Pascal Schneider, Michael Cheeseman

Dis Model Mech. 2022 Mar 1; 15(3): dmm049034. Published online 2022 Mar 30. doi: 10.1242/dmm.049034

PMCID:: PMC8990926

Abstract Article

Select item 87409357.

Limb development genes underlie variation in human fingerprint patterns

Jinxi Li, James D. Glover, Haiguo Zhang, Meifang Peng, Jingze Tan, Chandana Basu Mallick, Dan Hou, Yajun Yang, Sijie Wu, Yu Liu, Qianqian Peng, Shijie C. Zheng, Edie I. Crosse, Alexander Medvinsky, Richard A. Anderson, Helen Brown, Ziyu Yuan, Shen Zhou, Yanqing Xu, John P. Kemp, Yvonne Y.W. Ho, Danuta Z. Loesch, Lizhong Wang, Yingxiang Li, Senwei Tang, Xiaoli Wu, Robin G. Walters, Kuang Lin, Ruogu Meng, Jun Lv, Jonathan M. Chernus, Katherine Neiswanger, Eleanor Feingold, David M. Evans, Sarah E. Medland, Nicholas G. Martin, Seth M. Weinberg, Mary L. Marazita, Gang Chen, Zhengming Chen, Yong Zhou, Michael Cheeseman, Lan Wang, Li Jin, Denis J. Headon, Sijia Wang

Cell. 2022 Jan 6; 185(1): 95–112.e18. doi: 10.1016/j.cell.2021.12.008

PMCID:: PMC8740935

Abstract Article

Select item 65144108.

Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth

Philip Tomann, Ralf Paus, Sarah E. Millar, Claus Scheidereit, Ruth Schmidt-Ullrich

Development. 2016 May 1; 143(9): 1512–1522. Published online 2016 May 3. doi: 10.1242/dev.130898

PMCID:: PMC6514410

Abstract Article

Select item 65143029.

Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling

Youngwook Ahn, Carrie Sims, Jennifer M. Logue, Scott D. Weatherbee, Robb Krumlauf

Development. 2013 Feb 1; 140(3): 583–593. Published online 2013 Jan 4. doi: 10.1242/dev.085118

PMCID:: PMC6514302

Abstract Article

Select item 645135410.

Edar is a downstream target of beta-catenin and drives collagen accumulation in the mouse prostate

Kyle A. Wegner, Vatsal Mehta, Jeanette A. Johansson, Brett R. Mueller, Kimberly P. Keil, Lisa L. Abler, Paul C. Marker, M. Mark Taketo, Denis J. Headon, Chad M. Vezina

Biol Open. 2019 Mar 15; 8(3): bio037945. Published online 2019 Feb 11. doi: 10.1242/bio.037945

PMCID:: PMC6451354

Abstract Article PDF–1.4M

Select item 638217511.

Modeling Edar expression reveals the hidden dynamics of tooth signaling center patterning

Alexa Sadier, Monika Twarogowska, Klara Steklikova, Luke Hayden, Anne Lambert, Pascal Schneider, Vincent Laudet, Maria Hovorakova, Vincent Calvez, Sophie Pantalacci

PLoS Biol. 2019 Feb; 17(2): e3000064. Published online 2019 Feb 7. doi: 10.1371/journal.pbio.3000064

PMCID:: PMC6382175

Abstract Article PDF–3.4M

Select item 637084312.

The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death

Jonathan Vial, Amélie Royet, Philippe Cassier, Antonin Tortereau, Sarah Dinvaut, Denis Maillet, Lise Gratadou-Hupon, Marion Creveaux, Alexa Sadier, Garance Tondeur, Sophie Léon, Lauriane Depaepe, Sophie Pantalacci, Arnaud de la Fouchardière, Olivier Micheau, Stéphane Dalle, Vincent Laudet, Patrick Mehlen, Marie Castets

Cell Death Differ. 2019 Mar; 26(3): 443–454. Published online 2018 May 31. doi: 10.1038/s41418-018-0128-1

PMCID:: PMC6370843

Abstract Article PDF–2.0M

Select item 637031213.

Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent

Ka-Wai Mok, Nivedita Saxena, Nicholas Heitman, Laura Grisanti, Devika Srivastava, Mauro Muraro, Tina Jacob, Rachel Sennett, Zichen Wang, Yutao Su, Lu M. Yang, Avi Ma’ayan, David M. Ornitz, Maria Kasper, Michael Rendl

Dev Cell. Author manuscript; available in PMC 2020 Jan 7.

Published in final edited form as: Dev Cell. 2019 Jan 7; 48(1): 32–48.e5. Published online 2018 Dec 27. doi: 10.1016/j.devcel.2018.11.034

PMCID:: PMC6370312

Abstract Article PDF–4.9M

Select item 636153014.

Single-cell analysis reveals a hair follicle dermal niche molecular differentiation trajectory that begins prior to morphogenesis

Khusali Gupta, Jonathan Levinsohn, George Linderman, Demeng Chen, Thomas Yang Sun, Danni Dong, M. Mark Taketo, Marcus Bosenberg, Yuval Kluger, Keith Choate, Peggy Myung

Dev Cell. Author manuscript; available in PMC 2020 Jan 7.

Published in final edited form as: Dev Cell. 2019 Jan 7; 48(1): 17–31.e6. Published online 2018 Dec 27. doi: 10.1016/j.devcel.2018.11.032

PMCID:: PMC6361530

Abstract Article PDF–2.8M

Select item 617729215.

Single cell and open chromatin analysis reveals molecular origin of epidermal cells of the skin

Xiying Fan, Dongmei Wang, Jeremy Evan Burgmaier, Yudong Teng, Rose-Anne Romano, Satrajit Sinha, Rui Yi

Dev Cell. Author manuscript; available in PMC 2019 Oct 8.

Published in final edited form as: Dev Cell. 2018 Oct 8; 47(1): 21–37.e5. Published online 2018 Sep 13. doi: 10.1016/j.devcel.2018.08.010

Correction in:: Dev Cell. 2018 Oct 8; 47(1): 133.

PMCID:: PMC6177292

Abstract Article PDF–4.4M

Select item 610733416.

Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation

Leah C Biggs, Otto JM Mäkelä, Satu-Marja Myllymäki, Rishi Das Roy, Katja Närhi, Johanna Pispa, Tuija Mustonen, Marja L Mikkola

eLife. 2018; 7: e36468. Published online 2018 Jul 31. doi: 10.7554/eLife.36468

PMCID:: PMC6107334

Abstract Article PDF–8.7M

Select item 561388317.

The Impact of the Eda Pathway on Tooth Root Development

J.M. Fons Romero, H. Star, R. Lav, S. Watkins, M. Harrison, M. Hovorakova, D. Headon, A.S. Tucker

J Dent Res. 2017 Oct; 96(11): 1290–1297. Published online 2017 Aug 16. doi: 10.1177/0022034517725692

PMCID:: PMC5613883

Abstract Article PDF–1.0M

Select item 550595218.

Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty

Teresa Elo, Päivi H. Lindfors, Qiang Lan, Maria Voutilainen, Ewelina Trela, Claes Ohlsson, Sung-Ho Huh, David M. Ornitz, Matti Poutanen, Beatrice A. Howard, Marja L. Mikkola

Sci Rep. 2017; 7: 5049. Published online 2017 Jul 11. doi: 10.1038/s41598-017-04637-1

PMCID:: PMC5505952

Abstract Article PDF–6.1M

Select item 529582119.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 517995020.

Ectodysplasin signalling deficiency in mouse models of hypohidrotic ectodermal dysplasia leads to middle ear and nasal pathology

Ali Azar, Chiara Piccinelli, Helen Brown, Denis Headon, Michael Cheeseman

Hum Mol Genet. 2016 Aug 15; 25(16): 3564–3577. Published online 2016 Jul 4. doi: 10.1093/hmg/ddw202

PMCID:: PMC5179950

Abstract Article PDF–2.1M

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