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Select item 102541181.

Increased Ca²⁺ signaling through Ca_V1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties

Haiyin Li, Antonion Korcari, David Ciufo, Christopher L. Mendias, Scott A. Rodeo, Mark R. Buckley, Alayna E. Loiselle, Geoffrey S. Pitt, Chike Cao

FASEB J. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: FASEB J. 2023 Jul; 37(7): e23007. doi: 10.1096/fj.202300607R

PMCID:: PMC10254118

Abstract Article PDF–3.3M

Select item 100407682.

Digits in a dish: An in vitro system to assess the molecular genetics of hand/foot development at single-cell resolution

Allison M. Fuiten, Yuki Yoshimoto, Chisa Shukunami, H. Scott Stadler

Front Cell Dev Biol. 2023; 11: 1135025. Published online 2023 Mar 13. doi: 10.3389/fcell.2023.1135025

PMCID:: PMC10040768

Abstract Article PDF–5.3M

Select item 98528793.

Transcriptomic analysis of the upper lip and primary palate development in mice

Sini Cai, Nuo Si, Yanyang Wang, Ningbei Yin

Front Genet. 2022; 13: 1039850. Published online 2023 Jan 6. doi: 10.3389/fgene.2022.1039850

PMCID:: PMC9852879

Abstract Article PDF–7.2M

Select item 95952114.

Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors

Marco Angelozzi, Renata Pellegrino da Silva, Michael V. Gonzalez, Véronique Lefebvre

Cell Rep. Author manuscript; available in PMC 2022 Oct 25.

Published in final edited form as: Cell Rep. 2022 Jul 12; 40(2): 111045. doi: 10.1016/j.celrep.2022.111045

PMCID:: PMC9595211

Abstract Article PDF–4.7M

Select item 93815045.

Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis

Junjun Jing, Jifan Feng, Yuan Yuan, Tingwei Guo, Jie Lei, Fei Pei, Thach-Vu Ho, Yang Chai

Nat Commun. 2022; 13: 4803. Published online 2022 Aug 16. doi: 10.1038/s41467-022-32490-y

PMCID:: PMC9381504

Abstract Article PDF–6.6M

Select item 88047436.

Tenomodulin and Chondromodulin-1 Are Both Required to Maintain Biomechanical Function and Prevent Intervertebral Disc Degeneration

Theodor Di Pauli von Treuheim, Olivia M. Torre, Emily D. Ferreri, Philip Nasser, Angelica Abbondandolo, Manuel Delgado Caceres, Dasheng Lin, Denitsa Docheva, James C. Iatridis

Cartilage. 2021 Dec; 13(2 Suppl): 604S–614S. Published online 2021 Sep 4. doi: 10.1177/19476035211029696

PMCID:: PMC8804743

Abstract Article PDF–1.4M

Select item 85714177.

Tenomodulin knockout mice exhibit worse late healing outcomes with augmented trauma-induced heterotopic ossification of Achilles tendon

Manuel Delgado Caceres, Katharina Angerpointner, Michael Galler, Dasheng Lin, Philipp A. Michel, Christoph Brochhausen, Xin Lu, Adithi R. Varadarajan, Jens Warfsmann, Richard Stange, Volker Alt, Christian G. Pfeifer, Denitsa Docheva

Cell Death Dis. 2021 Nov; 12(11): 1049. Published online 2021 Nov 5. doi: 10.1038/s41419-021-04298-z

PMCID:: PMC8571417

Abstract Article PDF–11M

Select item 83553378.

The developing mouse coronal suture at single-cell resolution

D’Juan T. Farmer, Hana Mlcochova, Yan Zhou, Nils Koelling, Guanlin Wang, Neil Ashley, Helena Bugacov, Hung-Jhen Chen, Riana Parvez, Kuo-Chang Tseng, Amy E. Merrill, Robert E. Maxson, Jr., Andrew O. M. Wilkie, J. Gage Crump, Stephen R. F. Twigg

Nat Commun. 2021; 12: 4797. Published online 2021 Aug 10. doi: 10.1038/s41467-021-24917-9

PMCID:: PMC8355337

Abstract Article PDF–9.6M

Select item 82111069.

The Scleraxis Transcription Factor Directly Regulates Multiple Distinct Molecular and Cellular Processes During Early Tendon Cell Differentiation

Han Liu, Jingyue Xu, Yu Lan, Hee-Woong Lim, Rulang Jiang

Front Cell Dev Biol. 2021; 9: 654397. Published online 2021 Jun 3. doi: 10.3389/fcell.2021.654397

PMCID:: PMC8211106

Abstract Article PDF–2.0M

Select item 739063910.

A single cell transcriptional atlas of early synovial joint development

Qin Bian, Yu-Hao Cheng, Jordan P. Wilson, Emily Y. Su, Dong Won Kim, Hong Wang, Sooyeon Yoo, Seth Blackshaw, Patrick Cahan

Development. 2020 Jul 15; 147(14): dev185777. Published online 2020 Jul 20. doi: 10.1242/dev.185777

PMCID:: PMC7390639

Abstract Article

Select item 737917611.

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis

Greg Holmes, Ana S. Gonzalez-Reiche, Na Lu, Xianxiao Zhou, Joshua Rivera, Divya Kriti, Robert Sebra, Anthony A. Williams, Michael J. Donovan, S. Steven Potter, Dalila Pinto, Bin Zhang, Harm van Bakel, Ethylin Wang Jabs

Cell Rep. Author manuscript; available in PMC 2020 Jul 24.

Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107871. doi: 10.1016/j.celrep.2020.107871

PMCID:: PMC7379176

Abstract Article PDF–3.0M

Select item 705913712.

Loss of tenomodulin expression is a risk factor for age‐related intervertebral disc degeneration

Dasheng Lin, Paolo Alberton, Manuel Delgado Caceres, Carina Prein, Hauke Clausen‐Schaumann, Jian Dong, Attila Aszodi, Chisa Shukunami, James C Iatridis, Denitsa Docheva

Aging Cell. 2020 Mar; 19(3): e13091. Published online 2020 Feb 21. doi: 10.1111/acel.13091

PMCID:: PMC7059137

Abstract Article PDF–2.6M

Select item 702586113.

Tgfβ signaling is critical for maintenance of the tendon cell fate

Guak-Kim Tan, Brian A Pryce, Anna Stabio, John V Brigande, ChaoJie Wang, Zheng Xia, Sara F Tufa, Douglas R Keene, Ronen Schweitzer

eLife. 2020; 9: e52695. Published online 2020 Jan 21. doi: 10.7554/eLife.52695

PMCID:: PMC7025861

Abstract Article PDF–4.0M

Select item 691953214.

Common cellular origin and diverging developmental programs for different sesamoid bones

Shai Eyal, Sarah Rubin, Sharon Krief, Lihi Levin, Elazar Zelzer

Development. 2019 Feb 15; 146(4): dev167452. Published online 2019 Feb 28. doi: 10.1242/dev.167452

PMCID:: PMC6919532

Abstract Article

Select item 668576215.

Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia

Dirk Hubmacher, Nandaraj Taye, Zerina Balic, Stetson Thacker, Sheila M. Adams, David E. Birk, Ronen Schweitzer, Suneel S. Apte

Matrix Biol. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Matrix Biol. 2019 Sep; 82: 38–53. Published online 2019 Feb 7. doi: 10.1016/j.matbio.2019.02.001

PMCID:: PMC6685762

Abstract Article PDF–1.3M

Select item 592886816.

The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification

Timothy J. Mead, Daniel R. McCulloch, Jason C. Ho, Yaoyao Du, Sheila M. Adams, David E. Birk, Suneel S. Apte

JCI Insight. 2018 Apr 5; 3(7): e92941. Published online 2018 Apr 5. doi: 10.1172/jci.insight.92941

PMCID:: PMC5928868

Abstract Article PDF–3.2M

Select item 581664117.

Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes

Chisa Shukunami, Aki Takimoto, Yuriko Nishizaki, Yuki Yoshimoto, Seima Tanaka, Shigenori Miura, Hitomi Watanabe, Tetsushi Sakuma, Takashi Yamamoto, Gen Kondoh, Yuji Hiraki

Sci Rep. 2018; 8: 3155. Published online 2018 Feb 16. doi: 10.1038/s41598-018-21194-3

PMCID:: PMC5816641

Abstract Article PDF–2.8M

Select item 568267518.

Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing

Dasheng Lin, Paolo Alberton, Manuel Delgado Caceres, Elias Volkmer, Matthias Schieker, Denitsa Docheva

Cell Death Dis. 2017 Oct; 8(10): e3116. Published online 2017 Oct 12. doi: 10.1038/cddis.2017.510

PMCID:: PMC5682675

Abstract Article PDF–7.8M

Select item 547820719.

Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load

Sarah Dex, Paolo Alberton, Lena Willkomm, Thomas Söllradl, Sandra Bago, Stefan Milz, Mehdi Shakibaei, Anita Ignatius, Wilhelm Bloch, Hauke Clausen-Schaumann, Chisa Shukunami, Matthias Schieker, Denitsa Docheva

EBioMedicine. 2017 Jun; 20: 240–254. Published online 2017 May 5. doi: 10.1016/j.ebiom.2017.05.003