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Items: 1 to 20 of 30

1.
CRAT links cholesterol metabolism to innate immune responses in the heart
Hua Mao, Aude Angelini, Shengyu Li, Guangyu Wang, Luge Li, Cam Patterson, Xinchun Pi, Liang Xie
Nat Metab. Author manuscript; available in PMC 2023 Nov 29.
Published in final edited form as: Nat Metab. 2023 Aug; 5(8): 1382–1394. Published online 2023 Jul 13. doi: 10.1038/s42255-023-00844-5
PMCID:
PMC10685850
AbstractArticlePDF–4.4M
2.
Carnitine acetyltransferase deficiency mediates mitochondrial dysfunction‐induced cellular senescence in dermal fibroblasts
Min Ji Song, Chi‐Hyun Park, Haesoo Kim, Sangbum Han, Si Hyung Lee, Dong Hun Lee, Jin Ho Chung
Aging Cell. 2023 Nov; 22(11): e14000. Published online 2023 Oct 13. doi: 10.1111/acel.14000
PMCID:
PMC10652321
AbstractArticlePDF–24M
3.
Pyruvate-supported flux through medium chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles
Timothy R. Koves, Guo-Fang Fang Zhang, Michael T. Davidson, Alec B. Chaves, Scott B. Crown, Jordan M. Johnson, Dorothy H. Slentz, Paul A. Grimsrud, Deborah M. Muoio
Cell Metab. Author manuscript; available in PMC 2024 Jun 6.
Published in final edited form as: Cell Metab. 2023 Jun 6; 35(6): 1038–1056.e8. Published online 2023 Apr 14. doi: 10.1016/j.cmet.2023.03.016
PMCID:
PMC10330230
AbstractArticlePDF–2.9M
4.
Nicotinamide riboside supplementation confers marginal metabolic benefits in obese mice without remodeling the muscle acetyl-proteome
Ashley S. Williams, Timothy R. Koves, Yasminye D. Pettway, James A. Draper, Dorothy H. Slentz, Paul A. Grimsrud, Olga R. Ilkayeva, Deborah M. Muoio
iScience. 2022 Jan 21; 25(1): 103635. Published online 2021 Dec 16. doi: 10.1016/j.isci.2021.103635
PMCID:
PMC8741497
AbstractArticlePDF–4.4M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion
Dassine Berdous, Xavier Berney, Ana Rodriguez Sanchez-Archidona, Maxime Jan, Clara Roujeau, Isabel C. Lopez-Mejia, Randall Mynatt, Bernard Thorens
Mol Metab. 2020 Jul; 37: 100993. Published online 2020 Apr 13. doi: 10.1016/j.molmet.2020.100993
PMCID:
PMC7225740
AbstractArticlePDF–2.0M
7.
Disruption of acetyl-lysine turnover in muscle mitochondria promotes insulin resistance and redox stress without overt respiratory dysfunction
Ashley S. Williams, Timothy R. Koves, Michael T. Davidson, Scott B. Crown, Kelsey H. Fisher-Wellman, Maria J. Torres, James A. Draper, Tara M. Narowski, Dorothy H. Slentz, Louise Lantier, David H. Wasserman, Paul A. Grimsrud, Deborah M. Muoio
Cell Metab. Author manuscript; available in PMC 2021 Jan 7.
Published in final edited form as: Cell Metab. 2020 Jan 7; 31(1): 131–147.e11. Published online 2019 Dec 5. doi: 10.1016/j.cmet.2019.11.003
PMCID:
PMC6952241
AbstractArticlePDF–2.1M
8.
Carnitine Acetyltransferase in AgRP Neurons Is Required for the Homeostatic Adaptation to Restricted Feeding in Male Mice
Alex Reichenbach, Mathieu Mequinion, Jacqueline A Bayliss, Sarah H Lockie, Moyra B Lemus, Randall L Mynatt, Romana Stark, Zane B Andrews
Endocrinology. 2018 Jun; 159(6): 2473–2483. Published online 2018 Apr 24. doi: 10.1210/en.2018-00131
PMCID:
PMC6692886
AbstractArticle
9.
Proximal Tubular Cell–Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis
Claudia Kruger, Trang-Tiffany Nguyen, Chelsea Breaux, Alana Guillory, Margaret Mangelli, Kevin T. Fridianto, Jean-Paul Kovalik, David H. Burk, Robert C. Noland, Randall Mynatt, Krisztian Stadler
Diabetes. 2019 Apr; 68(4): 819–831. Published online 2019 Feb 6. doi: 10.2337/db18-0090
PMCID:
PMC6425873
AbstractArticlePDF–2.3M
10.
The carnitine acetyltransferase gene (CRAT): A characterization of porcine transcripts with insights into the 5’-end variants of mammalian transcripts and their possible sub-cellular localization
Annie Robic, Thomas Faraut, Laurence Liaubet, Denis Milan
Cell Mol Biol Lett. 2009 Mar; 14(1): 90–99. Published online 2008 Oct 6. doi: 10.2478/s11658-008-0036-3
PMCID:
PMC6275765
SummaryPDF–571K
11.
Chemical cross-linking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue
Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Andrew Keller, Rong Tian, James E. Bruce
Cell Syst. Author manuscript; available in PMC 2019 Jan 24.
Published in final edited form as: Cell Syst. 2018 Jan 24; 6(1): 136–141.e5. Published online 2017 Nov 29. doi: 10.1016/j.cels.2017.10.017
PMCID:
PMC5799023
AbstractArticlePDF–730K
12.
The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes
Fan Liu, Philip Lössl, Beverley M. Rabbitts, Robert S. Balaban, Albert J. R. Heck
Mol Cell Proteomics. 2018 Feb; 17(2): 216–232. Published online 2017 Dec 8. doi: 10.1074/mcp.RA117.000470
PMCID:
PMC5795388
AbstractArticlePDF–4.4M
13.
Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry
Devin K. Schweppe, Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Shane E. Kruse, Rudy Stuppard, David J. Marcinek, Gerald S. Shadel, Rong Tian, James E. Bruce
Proc Natl Acad Sci U S A. 2017 Feb 14; 114(7): 1732–1737. Published online 2017 Jan 27. doi: 10.1073/pnas.1617220114
PMCID:
PMC5321032
AbstractArticlePDF–1.1M
14.
Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation
Emily L. Goldberg, Vishwa Deep Dixit
Mol Metab. 2017 Feb; 6(2): 219–225. Published online 2017 Jan 3. doi: 10.1016/j.molmet.2016.12.008
PMCID:
PMC5279934
AbstractArticlePDF–1.5M
15.
The Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-induced Lysine Acetylation of Mitochondrial Proteins
Michael N. Davies, Lilja Kjalarsdottir, J. Will Thompson, Laura G. Dubois, Robert D. Stevens, Olga R. Ilkayeva, M. Julia Brosnan, Timothy P. Rolph, Paul A. Grimsrud, Deborah M. Muoio
Cell Rep. Author manuscript; available in PMC 2016 Feb 15.
Published in final edited form as: Cell Rep. 2016 Jan 12; 14(2): 243–254. Published online 2015 Dec 31. doi: 10.1016/j.celrep.2015.12.030
PMCID:
PMC4754083
AbstractArticlePDF–2.1M
16.
Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue During Exercise
Sarah E. Seiler, Timothy R. Koves, Jessica R. Gooding, Kari E. Wong, Robert S. Stevens, Olga R. Ilkayeva, April H. Wittmann, Karen L. DeBalsi, Michael N. Davies, Lucas Lindeboom, Patrick Schrauwen, Vera B. Schrauwen-Hinderling, Deborah M. Muoio
Cell Metab. Author manuscript; available in PMC 2016 Jul 7.
Published in final edited form as: Cell Metab. 2015 Jul 7; 22(1): 65–76. doi: 10.1016/j.cmet.2015.06.003
PMCID:
PMC4754082
AbstractArticlePDF–1.3M
17.
Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome
Julianne H. Grose, Kelsey Langston, Xiaohui Wang, Shayne Squires, Soumyajit Banerjee Mustafi, Whitney Hayes, Jonathan Neubert, Susan K. Fischer, Matthew Fasano, Gina Moore Saunders, Qiang Dai, Elisabeth Christians, E. Douglas Lewandowski, Peipei Ping, Ivor J. Benjamin
PLoS One. 2015; 10(10): e0133994. Published online 2015 Oct 14. doi: 10.1371/journal.pone.0133994
PMCID:
PMC4605610
AbstractArticlePDF–6.8M
18.
Muscle-specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility
Deborah M. Muoio, Robert C. Noland, Jean-Paul Kovalik, Sarah E. Seiler, Michael N. Davies, Karen L. DeBalsi, Olga R. Ilkayeva, Robert D. Stevens, Indu Kheterpal, Jingying Zhang, Jeffrey D. Covington, Sudip Bajpeyi, Eric Ravussin, William Kraus, Timothy R. Koves, Randall L. Mynatt
Cell Metab. Author manuscript; available in PMC 2013 May 2.
Published in final edited form as: Cell Metab. 2012 May 2; 15(5): 764–777. doi: 10.1016/j.cmet.2012.04.005
PMCID:
PMC3348515
AbstractArticlePDF–5.9M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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