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Select item 108218741.

Single-cell multiomics decodes regulatory programs for mouse secondary palate development

Fangfang Yan, Akiko Suzuki, Chihiro Iwaya, Guangsheng Pei, Xian Chen, Hiroki Yoshioka, Meifang Yu, Lukas M. Simon, Junichi Iwata, Zhongming Zhao

Nat Commun. 2024; 15: 821. Published online 2024 Jan 27. doi: 10.1038/s41467-024-45199-x

PMCID:: PMC10821874

Abstract Article PDF–6.4M

Select item 107882692.

Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development

Huahua Liu, Rui Zhou, Shanshan Li, Jinling Dong, Yuan Fang, Yuru Luo, Hongyu Su, Baochang Lai, Lingli Liang, Donghong Zhang, Yanmin Zhang, John Y-J. Shyy, Bin Zhou, Zuyi Yuan, Yidong Wang

iScience. 2024 Jan 19; 27(1): 108722. Published online 2023 Dec 13. doi: 10.1016/j.isci.2023.108722

PMCID:: PMC10788269

Abstract Article PDF–11M

Select item 107838723.

Activin A marks a novel progenitor cell population during fracture healing and reveals a therapeutic strategy

Lutian Yao, Jiawei Lu, Leilei Zhong, Yulong Wei, Tao Gui, Luqiang Wang, Jaimo Ahn, Joel D Boerckel, Danielle Rux, Christina Mundy, Ling Qin, Maurizio Pacifici

eLife. 2023; 12: e89822. Published online 2023 Dec 11. doi: 10.7554/eLife.89822

PMCID:: PMC10783872

Abstract Article PDF–19M

Select item 106541014.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 105057325.

Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure

Penny A. F. Whiley, Michael C. M. Luu, Liza O’Donnell, David J. Handelsman, Kate L. Loveland

Front Endocrinol (Lausanne) 2023; 14: 1234712. Published online 2023 Sep 1. doi: 10.3389/fendo.2023.1234712

PMCID:: PMC10505732

Abstract Article PDF–9.9M

Select item 104107176.

Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve

Camilla H. K. Hughes, Olivia E. Smith, Marie-Charlotte Meinsohn, Mylène Brunelle, Nicolas Gévry, Bruce D. Murphy

Proc Natl Acad Sci U S A. 2023 Aug 8; 120(32): e2220849120. Published online 2023 Jul 26. doi: 10.1073/pnas.2220849120

PMCID:: PMC10410717

Abstract Article PDF–3.9M

Select item 103226857.

Impaired angiogenesis in diabetic critical limb ischemia is mediated by a miR-130b/INHBA signaling axis

Henry S. Cheng, Daniel Pérez-Cremades, Rulin Zhuang, Anurag Jamaiyar, Winona Wu, Jingshu Chen, Aspasia Tzani, Lauren Stone, Jorge Plutzky, Terence E. Ryan, Philip P. Goodney, Mark A. Creager, Marc S. Sabatine, Marc P. Bonaca, Mark W. Feinberg

JCI Insight. 2023 May 22; 8(10): e163041. Published online 2023 May 22. doi: 10.1172/jci.insight.163041

PMCID:: PMC10322685

Abstract Article PDF–9.1M

Select item 99104588.

Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals

Hei Yeun Koo, Min-A Kim, Hyehyun Min, Jae Yeon Hwang, Meenakshi Prajapati-DiNubila, Kwan Soo Kim, Martin M. Matzuk, Juw Won Park, Angelika Doetzlhofer, Un-Kyung Kim, Jinwoong Bok

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2213099120. Published online 2022 Dec 28. doi: 10.1073/pnas.2213099120

PMCID:: PMC9910458

Abstract Article PDF–11M

Select item 98528799.

Transcriptomic analysis of the upper lip and primary palate development in mice

Sini Cai, Nuo Si, Yanyang Wang, Ningbei Yin

Front Genet. 2022; 13: 1039850. Published online 2023 Jan 6. doi: 10.3389/fgene.2022.1039850

PMCID:: PMC9852879

Abstract Article PDF–7.2M

Select item 984524210.

In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma

Seiji Taniguchi, Takahiro Matsui, Kenji Kimura, Soichiro Funaki, Yu Miyamoto, Yutaka Uchida, Takao Sudo, Junichi Kikuta, Tetsuya Hara, Daisuke Motooka, Yu-Chen Liu, Daisuke Okuzaki, Eiichi Morii, Noriaki Emoto, Yasushi Shintani, Masaru Ishii

Nat Commun. 2023; 14: 143. Published online 2023 Jan 17. doi: 10.1038/s41467-022-35701-8

PMCID:: PMC9845242

Abstract Article PDF–4.1M

Select item 920540211.

The Impact of Activin A on Fetal Gonocytes: Chronic Versus Acute Exposure Outcomes

Sarah C. Moody, Penny A. F. Whiley, Patrick S. Western, Kate L. Loveland

Front Endocrinol (Lausanne) 2022; 13: 896747. Published online 2022 May 31. doi: 10.3389/fendo.2022.896747

PMCID:: PMC9205402

Abstract Article PDF–19M

Select item 880384812.

Visceral adipose tissue remodeling in pancreatic ductal adenocarcinoma cachexia: the role of activin A signaling

Pauline C. Xu, Mikyoung You, Seok-Yeong Yu, Yi Luan, Maya Eldani, Thomas C. Caffrey, Paul M. Grandgenett, Kelly A. O’Connell, Surendra K. Shukla, Chandramohan Kattamuri, Michael A. Hollingsworth, Pankaj K. Singh, Thomas B. Thompson, Soonkyu Chung, So-Youn Kim

Sci Rep. 2022; 12: 1659. Published online 2022 Jan 31. doi: 10.1038/s41598-022-05660-7

PMCID:: PMC8803848

Abstract Article PDF–3.2M

Select item 877419513.

Dysregulation of Npas4 and Inhba expression and an altered excitation–inhibition balance are associated with cognitive deficits in DBA/2 mice

Kristin Oberländer, Victoria Witte, Anne Stephanie Mallien, Peter Gass, C. Peter Bengtson, Hilmar Bading

Learn Mem. 2022 Feb; 29(2): 55–70. Published online 2022 Feb. doi: 10.1101/lm.053527.121

PMCID:: PMC8774195

Abstract Article PDF–2.4M

Select item 837994614.

Local versus systemic control of bone and skeletal muscle mass by components of the transforming growth factor-β signaling pathway

Yewei Liu, Adam Lehar, Renata Rydzik, Harshpreet Chandok, Yun-Sil Lee, Daniel W. Youngstrom, Joshy George, Martin M. Matzuk, Emily L. Germain-Lee, Se-Jin Lee

Proc Natl Acad Sci U S A. 2021 Aug 17; 118(33): e2111401118. Published online 2021 Aug 12. doi: 10.1073/pnas.2111401118

PMCID:: PMC8379946

Abstract Article PDF–1.8M

Select item 835533715.

The developing mouse coronal suture at single-cell resolution

D’Juan T. Farmer, Hana Mlcochova, Yan Zhou, Nils Koelling, Guanlin Wang, Neil Ashley, Helena Bugacov, Hung-Jhen Chen, Riana Parvez, Kuo-Chang Tseng, Amy E. Merrill, Robert E. Maxson, Jr., Andrew O. M. Wilkie, J. Gage Crump, Stephen R. F. Twigg

Nat Commun. 2021; 12: 4797. Published online 2021 Aug 10. doi: 10.1038/s41467-021-24917-9

PMCID:: PMC8355337

Abstract Article PDF–9.6M

Select item 831323916.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 829986617.

Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility and metabolic homeostasis in female mice

Emmi Rotgers, Barbara Nicol, Karina Rodriguez, Saniya Rattan, Jodi A. Flaws, Humphrey Hung-Chang Yao

FASEB J. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: FASEB J. 2021 Aug; 35(8): e21770. doi: 10.1096/fj.202100304R

PMCID:: PMC8299866

Abstract Article PDF–2.6M

Select item 823766618.

Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level

Ciro Maurizio Amato, Humphrey Hung-Chang Yao

Proc Natl Acad Sci U S A. 2021 Jun 22; 118(25): e2103856118. Published online 2021 Jun 21. doi: 10.1073/pnas.2103856118

PMCID:: PMC8237666

Abstract Article PDF–3.3M

Select item 797987319.

An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension

Gusty R. T. Ryanto, Koji Ikeda, Kazuya Miyagawa, Ly Tu, Christophe Guignabert, Marc Humbert, Tomoyuki Fujiyama, Masashi Yanagisawa, Ken-ichi Hirata, Noriaki Emoto

Nat Commun. 2021; 12: 1720. Published online 2021 Mar 19. doi: 10.1038/s41467-021-21961-3

PMCID:: PMC7979873

Abstract Article PDF–6.3M

Select item 787843820.

The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation

Bing Wu, Song Zhang, Zengli Guo, Yanmin Bi, Mingxia Zhou, Ping Li, Maryamsadat Seyedsadr, Xiaojiang Xu, Jian-liang Li, Silva Markovic-Plese, Yisong Y Wan

Immunity. Author manuscript; available in PMC 2022 Feb 9.

Published in final edited form as: Immunity. 2021 Feb 9; 54(2): 308–323.e6. Published online 2021 Jan 8. doi: 10.1016/j.immuni.2020.12.010