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Select item 108343121.

DBC1 maintains skeletal muscle integrity by enhancing myogenesis and preventing myofibre wasting

Na Liang, Jia He, Jiaqi Yan, Xueying Han, Xiaoqian Zhang, Yamei Niu, Wuga Sha, Jun Li

J Cachexia Sarcopenia Muscle. 2024 Feb; 15(1): 255–269. Published online 2023 Dec 7. doi: 10.1002/jcsm.13398

PMCID:: PMC10834312

Abstract Article PDF–2.9M

Select item 105223652.

SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells

Yan Wang, Jing-Miao Wang, Yuan Xiao, Xue-Bin Hu, Shu-Yu Zheng, Jia-Ling Fu, Lan Zhang, Yu-Wen Gan, Xing-Miao Liang, David Wan-Cheng Li

Aging (Albany NY) 2023 Sep 15; 15(17): 8812–8832. Published online 2023 Sep 7. doi: 10.18632/aging.205001

PMCID:: PMC10522365

Abstract Article PDF–1.8M

Select item 86323083.

Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy

Iram Khan Iqbal, Sapna Bajeli, Shivani Sahu, Shabir Ahmad Bhat, Ashwani Kumar

Autophagy. 2021; 17(11): 3511–3529. Published online 2021 Jan 30. doi: 10.1080/15548627.2021.1876342

PMCID:: PMC8632308

Abstract Article PDF–4.7M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 71743385.

The protein Deleted in Breast Cancer-1 (DBC1) regulates vascular response and formation of aortic dissection during Angiotensin II infusion

Laura Colman, Maria Caggiani, Alejandro Leyva, Mariana Bresque, Sally Liechocki, Clarissa M. Maya-Monteiro, Daniel Mazal, Carlos Batthyany, Aldo Calliari, Paola Contreras, Carlos Escande

Sci Rep. 2020; 10: 6772. Published online 2020 Apr 21. doi: 10.1038/s41598-020-63841-8

PMCID:: PMC7174338

Abstract Article PDF–7.2M

Select item 69025976.

TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination

Wei Li, Fen Li, Weiwei Lei, Zezhang Tao

Cell Commun Signal. 2019; 17: 162. Published online 2019 Dec 10. doi: 10.1186/s12964-019-0484-6

PMCID:: PMC6902597

Abstract Article PDF–2.4M

Select item 67797537.

A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo

Leonardo Santos, Laura Colman, Paola Contreras, Claudia C. Chini, Adriana Carlomagno, Alejandro Leyva, Mariana Bresque, Inés Marmisolle, Celia Quijano, Rosario Durán, Florencia Irigoín, Victoria Prieto-Echagüe, Mikkel H. Vendelbo, José R. Sotelo-Silveira, Eduardo N. Chini, Jose L. Badano, Aldo J. Calliari, Carlos Escande

Sci Rep. 2019; 9: 14381. Published online 2019 Oct 7. doi: 10.1038/s41598-019-50789-7

PMCID:: PMC6779753

Abstract Article PDF–6.0M

Select item 66827338.

LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function

Alexa K. Wade, Yanping Liu, Maigen M. Bethea, Eliana Toren, Hubert M. Tse, Chad S. Hunter

J Biol Chem. 2019 Aug 2; 294(31): 11728–11740. Published online 2019 Jun 11. doi: 10.1074/jbc.RA118.006985

PMCID:: PMC6682733

Abstract Article PDF–3.1M

Select item 66023009.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 630950010.

An insulin responsive sensor in the SIRT1 disordered region binds DBC1 and PACS-2 to control enzyme activity

Troy C. Krzysiak, Laurel Thomas, You-Jin Choi, Sylvain Auclair, Yiqi Qian, Shan Luan, Stephanie M. Krasnow, Laura L. Thomas, Leonardus M.I. Koharudin, Panayiotis V. Benos, Daniel L. Marks, Angela M. Gronenborn, Gary Thomas

Mol Cell. Author manuscript; available in PMC 2019 Dec 20.

Published in final edited form as: Mol Cell. 2018 Dec 20; 72(6): 985–998.e7. Published online 2018 Nov 8. doi: 10.1016/j.molcel.2018.10.007

PMCID:: PMC6309500

Abstract Article PDF–1.1M

Select item 624418311.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 564508212.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 464244013.

Deleted in Breast Cancer 1 (DBC1) suppresses B cell activation through RelB and is regulated by IKKα phosphorylation

Sinyi Kong, Hongxin Dong, Jianxun Song, Muthusamy Thiruppathi, Bellur S. Prabhakar, Quan Qiu, Zhenghong Lin, Eduardo Chini, Bin Zhang, Deyu Fang

J Immunol. Author manuscript; available in PMC 2016 Oct 15.

Published in final edited form as: J Immunol. 2015 Oct 15; 195(8): 3685–3693. Published online 2015 Sep 16. doi: 10.4049/jimmunol.1500713

PMCID:: PMC4642440

Abstract Article PDF–1.5M

Select item 448512714.

Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1

Yayi Gao, Jiayou Tang, Weiqian Chen, Qiang Li, Jia Nie, Fang Lin, Qingsi Wu, Zuojia Chen, Zhimei Gao, Huimin Fan, Andy Tsun, Jijia Shen, Guihua Chen, Zhongmin Liu, Zhenkun Lou, Nancy J. Olsen, Song Guo Zheng, Bin Li

Proc Natl Acad Sci U S A. 2015 Jun 23; 112(25): E3246–E3254. Published online 2015 Jun 9. doi: 10.1073/pnas.1421463112

PMCID:: PMC4485127

Abstract Article PDF–1.6M

Select item 448118815.

Hepatic SirT1-Dependent Gain-of-Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions

Li Qiang, Ning Kon, Wenhui Zhao, Le Jiang, Colette M. Knight, Carrie Welch, Utpal Pajvani, Wei Gu, Domenico Accili

Cell Rep. Author manuscript; available in PMC 2016 Jun 23.

Published in final edited form as: Cell Rep. 2015 Jun 23; 11(11): 1797–1808. Published online 2015 Jun 11. doi: 10.1016/j.celrep.2015.05.025

PMCID:: PMC4481188

Abstract Article PDF–2.1M

Select item 435118716.

DBC1 Functions as a Tumor Suppressor by Regulating p53 Stability

Bo Qin, Katherine Minter-Dykhouse, Jia Yu, Jun Zhang, Tongzheng Liu, Haoxing Zhang, Seung Baek Lee, Jung Jin Kim, Liewei Wang, Zhenkun Lou

Cell Rep. Author manuscript; available in PMC 2016 Mar 3.

Published in final edited form as: Cell Rep. 2015 Mar 3; 10(8): 1324–1334. Published online 2015 Feb 26. doi: 10.1016/j.celrep.2015.01.066

PMCID:: PMC4351187

Abstract Article PDF–2.3M

Select item 427480617.

Deleted in Breast Cancer 1 Limits Adipose Tissue Fat Accumulation and Plays a Key Role in the Development of Metabolic Syndrome Phenotype

Carlos Escande, Veronica Nin, Tamar Pirtskhalava, Claudia C.S. Chini, Tamar Tchkonia, James L. Kirkland, Eduardo N. Chini

Diabetes. 2015 Jan; 64(1): 12–22. Published online 2014 Jul 22. doi: 10.2337/db14-0192

PMCID:: PMC4274806

Abstract Article PDF–1.6M

Select item 417253218.

Deleted in Breast Cancer 1 regulates cellular senescence during obesity

Carlos Escande, Veronica Nin, Tamar Pirtskhalava, Claudia C Chini, Maria Thereza Barbosa, Angela Mathison, Raul Urrutia, Tamar Tchkonia, James L Kirkland, Eduardo N Chini

Aging Cell. 2014 Oct; 13(5): 951–953. Published online 2014 Jul 3. doi: 10.1111/acel.12235

PMCID:: PMC4172532

Abstract Article PDF–575K

Select item 407349419.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 393762820.

Deleted in Breast Cancer 1 (DBC1) Protein Regulates Hepatic Gluconeogenesis

Veronica Nin, Claudia C. S. Chini, Carlos Escande, Verena Capellini, Eduardo N. Chini

J Biol Chem. 2014 Feb 28; 289(9): 5518–5527. Published online 2014 Jan 10. doi: 10.1074/jbc.M113.512913

PMCID:: PMC3937628

Abstract Article PDF–1.6M

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