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Items: 1 to 20 of 133

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
VEO-IBD NOX1 variant highlights a structural region essential for NOX/DUOX catalytic activity
Josie Ward, Suisheng Zhang, Adam Sikora, Radoslaw Michalski, Yuting Yin, Aurora D'Alessio, Rachel M. McLoughlin, Vincent Jaquet, Franck Fieschi, Ulla G. Knaus
Redox Biol. 2023 Nov; 67: 102905. Published online 2023 Sep 27. doi: 10.1016/j.redox.2023.102905
PMCID:
PMC10571032
AbstractArticlePDF–8.7M
3.
The role of NADPH oxidase 1 in alcohol-induced oxidative stress injury of intestinal epithelial cells
Liuying Chen, Huikuan Chu, Lilin Hu, Zhonglin Li, Ling Yang, Xiaohua Hou
Cell Biol Toxicol. 2023; 39(5): 2345–2364. Published online 2022 May 31. doi: 10.1007/s10565-022-09725-1
PMCID:
PMC10547661
AbstractArticlePDF–18M
4.
Nox1-based NADPH oxidase regulates the Par protein complex activity to control cell polarization
Alejandra Valdivia, Charity Duran, Mingyoung Lee, Holly C. Williams, Moo-Yeol Lee, Alejandra San Martin
Front Cell Dev Biol. 2023; 11: 1231489. Published online 2023 Aug 11. doi: 10.3389/fcell.2023.1231489
PMCID:
PMC10457011
AbstractArticlePDF–4.8M
5.
NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation
Sjoerd van der Post, George M.H. Birchenough, Jason M. Held
Cell Rep. Author manuscript; available in PMC 2023 Jul 7.
Published in final edited form as: Cell Rep. 2021 Apr 6; 35(1): 108949. doi: 10.1016/j.celrep.2021.108949
PMCID:
PMC10327654
AbstractArticlePDF–2.1M
6.
Reactivity of renal and mesenteric resistance vessels to angiotensin II is mediated by NOXA1/NOX1 and superoxide signaling
Mark D. Stevenson, Aleksandr E. Vendrov, Xi Yang, Yuenmu Chen, Hernán A. Navarro, Nicholas Moss, Marschall S. Runge, William J. Arendshorst, Nageswara R. Madamanchi
Am J Physiol Renal Physiol. 2023 Apr 1; 324(4): F335–F352. Published online 2023 Feb 10. doi: 10.1152/ajprenal.00236.2022
PMCID:
PMC10026993
AbstractArticle
7.
NOX1 is essential for TNFα-induced intestinal epithelial ROS secretion and inhibits M cell signatures
Nai-Yun Hsu, Shikha Nayar, Kyle Gettler, Sayali Talware, Mamta Giri, Isaac Alter, Carmen Argmann, Ksenija Sabic, Tin Htwe Thin, Huai-Bin Mabel Ko, Robert Werner, Christopher Tastad, Thaddeus Stappenbeck, Aline Azabdaftari, Holm H. Uhlig, Ling-shiang Chuang, Judy H. Cho
Gut. Author manuscript; available in PMC 2024 Apr 1.
Published in final edited form as: Gut. 2023 Apr; 72(4): 654–662. Published online 2022 Oct 3. doi: 10.1136/gutjnl-2021-326305
PMCID:
PMC9998338
AbstractArticlePDF–2.3M
8.
Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury
Hannah Mason, Ganesha Rai, Arina Kozyr, Nathaniel De Jonge, Emily Gliniewicz, Lars J. Berg, Gal Wald, Cayce Dorrier, Mark J. Henderson, Alexey Zakharov, Tristan Dyson, John Audley, Anthony M. Pettinato, Elias Carvalho Padilha, Pranav Shah, Xin Xu, Thomas L. Leto, Anton Simeonov, Kol A. Zarember, Dorian B. McGavern, John I. Gallin
Redox Biol. 2023 Apr; 60: 102611. Published online 2023 Jan 18. doi: 10.1016/j.redox.2023.102611
PMCID:
PMC9894920
AbstractArticlePDF–2.4M
9.
Renal NOXA1/NOX1 Signaling Regulates Epithelial Sodium Channel and Sodium Retention in Angiotensin II-induced Hypertension
Aleksandr E. Vendrov, Mark D. Stevenson, Andrey Lozhkin, Takayuki Hayami, Nathan A. Holland, Xi Yang, Nicholas Moss, Hua Pan, Samuel A. Wickline, James D. Stockand, Marschall S. Runge, Nageswara R. Madamanchi, William J. Arendshorst
Antioxid Redox Signal. March 2022; 36(7-9): 550–566. Published online 2022 Mar 17. doi: 10.1089/ars.2021.0047
PMCID:
PMC8978567
AbstractArticlePDF–2.8M
10.
Inhibition of NOX1 Mitigates Blood Pressure Increases in Elastin Insufficiency
Angela Troia, Russell H Knutsen, Carmen M Halabi, Daniela Malide, Zu Xi Yu, Amanda Wardlaw-Pickett, Elise K Kronquist, Kit Man Tsang, Attila Kovacs, Robert P Mecham, Beth A Kozel
Function (Oxf) 2021; 2(3): zqab015. Published online 2021 Mar 15. doi: 10.1093/function/zqab015
PMCID:
PMC8248879
AbstractArticlePDF–1.2M
11.
NOX1/NADPH Oxidase Promotes Synaptic Facilitation Induced by Repeated D2 Receptor Stimulation: Involvement in Behavioral Repetition
Nozomi Asaoka, Masakazu Ibi, Hikari Hatakama, Koki Nagaoka, Kazumi Iwata, Misaki Matsumoto, Masato Katsuyama, Shuji Kaneko, Chihiro Yabe-Nishimura
J Neurosci. 2021 Mar 24; 41(12): 2780–2794. doi: 10.1523/JNEUROSCI.2121-20.2021
PMCID:
PMC8018731
AbstractArticlePDF–4.3M
12.
Quiescin/sulfhydryl oxidase 1b (QSOX1b) induces migration and proliferation of vascular smooth muscle cells by distinct redox pathways
Karime C. França, Pierina A. Martinez, Maiara L. Prado, Sze M. Lo, Beatriz E. Borges, Silvio M. Zanata, Alejandra San Martin, Lia S. Nakao
Arch Biochem Biophys. Author manuscript; available in PMC 2021 Mar 31.
Published in final edited form as: Arch Biochem Biophys. 2020 Jan 15; 679: 108220. Published online 2019 Dec 5. doi: 10.1016/j.abb.2019.108220
PMCID:
PMC8011465
AbstractArticlePDF–507K
13.
NOX1 Promotes Mesothelial–Mesenchymal Transition through Modulation of Reactive Oxygen Species–mediated Signaling
Wenyi Qin, Ann Jeffers, Shuzi Owens, Prashant Chauhan, Satoshi Komatsu, Guoqing Qian, Xia Guo, Mitsuo Ikebe, Steven Idell, Torry A. Tucker
Am J Respir Cell Mol Biol. 2021 Apr; 64(4): 492–503. doi: 10.1165/rcmb.2020-0077OC
PMCID:
PMC8008807
AbstractArticlePDF–2.0M
14.
Endothelium-restricted endothelin-1 overexpression in type 1 diabetes worsens atherosclerosis and immune cell infiltration via NOX1
Sofiane Ouerd, Noureddine Idris-Khodja, Michelle Trindade, Nathanne S Ferreira, Olga Berillo, Suellen C Coelho, Mario F Neves, Karin A Jandeleit-Dahm, Pierre Paradis, Ernesto L Schiffrin
Cardiovasc Res. 2021 Apr 1; 117(4): 1144–1153. Published online 2020 Jun 13. doi: 10.1093/cvr/cvaa168
PMCID:
PMC7983005
AbstractArticlePDF–1.2M
15.
Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors
Valeska Helfinger, Florian Freiherr von Gall, Nina Henke, Michael M. Kunze, Tobias Schmid, Flavia Rezende, Juliana Heidler, Ilka Wittig, Heinfried H. Radeke, Viola Marschall, Karen Anderson, Ajay M. Shah, Simone Fulda, Bernhard Brüne, Ralf P. Brandes, Katrin Schröder
Proc Natl Acad Sci U S A. 2021 Mar 16; 118(11): e2020152118. Published online 2021 Mar 8. doi: 10.1073/pnas.2020152118
PMCID:
PMC7980388
AbstractArticlePDF–1.5M
16.
Epithelial TLR4 signaling activates DUOX2 to induce microbiota-driven tumorigenesis
Juan F Burgueño, Julia Fritsch, Eddy E Gonzalez, Kevin S Landau, Ana M Santander, Irina Fernández, Hajar Hazime, Julie M Davies, Rebeca Santaolalla, Matthew C Phillips, Sophia Diaz, Rishu Dheer, Nivis Brito, Judith Pignac-Kobinger, Ester Fernández, Gregory E Conner, Maria T Abreu
Gastroenterology. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: Gastroenterology. 2021 Feb; 160(3): 797–808.e6. Published online 2020 Oct 24. doi: 10.1053/j.gastro.2020.10.031
PMCID:
PMC7879481
AbstractArticlePDF–1.3M
17.
NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis
Dina Vara, Reiner K. Mailer, Anuradha Tarafdar, Nina Wolska, Marco Heestermans, Sandra Konrath, Manuela Spaeth, Thomas Renné, Katrin Schröder, Giordano Pula
Arterioscler Thromb Vasc Biol. 2021 Feb; 41(2): 683–697. Published online 2020 Dec 3. doi: 10.1161/ATVBAHA.120.315565
PMCID:
PMC7837688
AbstractArticlePDF–7.7M
18.
Cyba-deficient mice display an increase in hematopoietic stem cells and an overproduction of immunoglobulins
Rodrigo Prieto-Bermejo, Marta Romo-González, Alejandro Pérez-Fernández, Ignacio García-Tuñón, Manuel Sánchez-Martín, Ángel Hernández-Hernández
Haematologica. 2021 Jan 1; 106(1): 142–153. Published online 2020 Jan 9. doi: 10.3324/haematol.2019.233064
PMCID:
PMC7776239
AbstractArticlePDF–2.3M
19.
Anaerobic respiration of NOX1-derived hydrogen peroxide licenses bacterial growth at the colonic surface
Brittany M. Miller, Megan J. Liou, Lillian F. Zhang, Henry Nguyen, Yael Litvak, Eva-Magdalena Schorr, Kyung Ku Jang, Connor R. Tiffany, Brian P. Butler, Andreas J. Bäumler
Cell Host Microbe. Author manuscript; available in PMC 2021 Dec 9.
Published in final edited form as: Cell Host Microbe. 2020 Dec 9; 28(6): 789–797.e5. doi: 10.1016/j.chom.2020.10.009
PMCID:
PMC7758056
AbstractArticlePDF–814K
20.
Epithelial-derived reactive oxygen species enable AppBCX-mediated aerobic respiration of Escherichia coli during intestinal inflammation
Rachael B. Chanin, Maria G. Winter, Luisella Spiga, Elizabeth R. Hughes, Wenhan Zhu, Savannah J. Taylor, Alexandre Arenales, Caroline C. Gillis, Lisa Büttner, Angel G. Jimenez, Madeline P. Smoot, Renato L. Santos, Sebastian E. Winter
Cell Host Microbe. Author manuscript; available in PMC 2021 Dec 9.
Published in final edited form as: Cell Host Microbe. 2020 Dec 9; 28(6): 780–788.e5. Published online 2020 Oct 13. doi: 10.1016/j.chom.2020.09.005
PMCID:
PMC7736183
AbstractArticlePDF–1.5M

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