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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104322742.

Immune sensing of food allergens promotes avoidance behaviour

Esther B. Florsheim, Nathaniel D. Bachtel, Jaime L. Cullen, Bruna G. C. Lima, Mahdieh Godazgar, Fernando Carvalho, Carolina P. Chatain, Marcelo R. Zimmer, Cuiling Zhang, Gregory Gautier, Pierre Launay, Andrew Wang, Marcelo O. Dietrich, Ruslan Medzhitov

Nature. 2023; 620(7974): 643–650. Published online 2023 Jul 12. doi: 10.1038/s41586-023-06362-4

PMCID:: PMC10432274

Abstract Article PDF–7.0M

Select item 93014873.

Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli

Zheng Cao, Chengcheng Huang, Fumin Lu, Xuequan Jiang, Yong Hu, Cheng Cao, Zijing Liu

Front Mol Neurosci. 2022; 15: 901466. Published online 2022 Jul 6. doi: 10.3389/fnmol.2022.901466

PMCID:: PMC9301487

Abstract Article PDF–5.7M

Select item 87509194.

Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation

Saltanat Ualiyeva, Evan Lemire, Evelyn C. Aviles, Caitlin Wong, Amelia A. Boyd, Juying Lai, Tao Liu, Ichiro Matsumoto, Nora A. Barrett, Joshua A. Boyce, Adam L. Haber, Lora G. Bankova

Sci Immunol. Author manuscript; available in PMC 2022 Jun 24.

Published in final edited form as: Sci Immunol. 2021 Dec 24; 6(66): eabj0474. Published online 2021 Dec 24. doi: 10.1126/sciimmunol.abj0474

PMCID:: PMC8750919

Abstract Article PDF–2.7M

Select item 80207535.

The CysLT₂R receptor mediates leukotriene C₄-driven acute and chronic itch

Tiphaine Voisin, Caroline Perner, Marie-Angele Messou, Stephanie Shiers, Saltanat Ualiyeva, Yoshihide Kanaoka, Theodore J. Price, Caroline L. Sokol, Lora G. Bankova, K. Frank Austen, Isaac M. Chiu

Proc Natl Acad Sci U S A. 2021 Mar 30; 118(13): e2022087118. Published online 2021 Mar 22. doi: 10.1073/pnas.2022087118

PMCID:: PMC8020753

Abstract Article PDF–1.6M

Select item 74694746.

Tuft cell-derived leukotrienes drive rapid anti-helminth immunity in the small intestine but are dispensable for anti-protist immunity

John W. McGinty, Hung-An Ting, Tyler E. Billipp, Marija S. Nadjsombati, Danish M. Khan, Nora A. Barrett, Hong-Erh Liang, Ichiro Matsumoto, Jakob von Moltke

Immunity. Author manuscript; available in PMC 2020 Sep 17.

Published in final edited form as: Immunity. 2020 Mar 17; 52(3): 528–541.e7. Published online 2020 Mar 10. doi: 10.1016/j.immuni.2020.02.005

PMCID:: PMC7469474

Abstract Article PDF–1.1M

Select item 65965297.

Hierarchical Specification of Pruriceptors by Runt-Domain Transcription Factor Runx1

Lu Qi, Chengcheng Huang, Xiaohua Wu, Yeqi Tao, Jingjing Yan, Tianyong Shi, Cheng Cao, Lu Han, Mengsheng Qiu, Qiufu Ma, Zijing Liu, Yang Liu

J Neurosci. 2017 May 31; 37(22): 5549–5561. doi: 10.1523/JNEUROSCI.0094-17.2017

PMCID:: PMC6596529

Abstract Article PDF–5.5M

Select item 64622438.

Cysteinyl Leukotriene Receptor 2 Drives Lung Immunopathology Through a Platelet and High Mobility Box 1-Dependent Mechanism

Tao Liu, Nora A. Barrett, Yoshihide Kanaoka, Kathleen Buchheit, Tanya M. Laidlaw, Denise Garofalo, Juying Lai, Howard R. Katz, Chunli Feng, Joshua A. Boyce

Mucosal Immunol. Author manuscript; available in PMC 2019 Jul 21.

Published in final edited form as: Mucosal Immunol. 2019 May; 12(3): 679–690. Published online 2019 Jan 21. doi: 10.1038/s41385-019-0134-8

PMCID:: PMC6462243

Abstract Article PDF–1.5M

Select item 63205079.

Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis

Ernest Duah, Lakshminarayan Reddy Teegala, Vinay Kondeti, Ravi K. Adapala, Venkateshwar G. Keshamouni, Yoshihide Kanaoka, K. Frank Austen, Charles K. Thodeti, Sailaja Paruchuri

Proc Natl Acad Sci U S A. 2019 Jan 2; 116(1): 199–204. Published online 2018 Dec 17. doi: 10.1073/pnas.1817325115

PMCID:: PMC6320507

Abstract Article PDF–1.5M

Select item 578024610.

Type 2 cysteinyl leukotriene receptors drive IL-33-dependent type 2 immunopathology and aspirin sensitivity

Tao Liu, Nora A. Barrett, Yoshihide Kanaoka, Eri Yoshimoto, Denise Garofalo, Haley Cirka, Chunli Feng, Joshua A. Boyce

J Immunol. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: J Immunol. 2018 Feb 1; 200(3): 915–927. Published online 2017 Dec 27. doi: 10.4049/jimmunol.1700603

PMCID:: PMC5780246

Abstract Article PDF–1.2M

Select item 556181811.

Aggravated inflammation and increased expression of cysteinyl leukotriene receptors in the brain after focal cerebral ischemia in AQP4-deficient mice

Wen-Zhen Shi, Chun-Zhen Zhao, Bing Zhao, Qiao-Juan Shi, Li-Hui Zhang, Yan-Fang Wang, San-Hua Fang, Yun-Bi Lu, Wei-Ping Zhang, Er-Qing Wei

Neurosci Bull. 2012 Dec; 28(6): 680–692. Published online 2012 Nov 6. doi: 10.1007/s12264-012-1281-z

PMCID:: PMC5561818

Abstract Article PDF–956K

Select item 553160112.

Leukotriene C4 potentiates IL-33 induced ILC2 activation and lung inflammation

Sean J. Lund, Alex Portillo, Kellen Cavagnero, Rachel E. Baum, Luay H. Naji, Jana H. Badrani, Amit Mehta, Michael Croft, David H. Broide, Taylor A. Doherty

J Immunol. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: J Immunol. 2017 Aug 1; 199(3): 1096–1104. Published online 2017 Jun 30. doi: 10.4049/jimmunol.1601569

PMCID:: PMC5531601

Abstract Article PDF–1.1M

Select item 520650413.

Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s

Jakob von Moltke, Claire E. O’Leary, Nora A. Barrett, Yoshihide Kanaoka, K. Frank Austen, Richard M. Locksley

J Exp Med. 2017 Jan; 214(1): 27–37. doi: 10.1084/jem.20161274

PMCID:: PMC5206504

Abstract Article PDF–1.7M

Select item 489667314.

Leukotriene E₄ elicits respiratory epithelial cell mucin release through the G-protein–coupled receptor, GPR99

Lora G. Bankova, Juying Lai, Eri Yoshimoto, Joshua A. Boyce, K. Frank Austen, Yoshihide Kanaoka, Nora A. Barrett

Proc Natl Acad Sci U S A. 2016 May 31; 113(22): 6242–6247. Published online 2016 May 16. doi: 10.1073/pnas.1605957113

PMCID:: PMC4896673

Abstract Article PDF–1.0M

Select item 386998715.

Leukotriene C₄ Activates Mouse Platelets in Plasma Exclusively Through the Type 2 Cysteinyl Leukotriene Receptor

Hannah E. Cummings, Tao Liu, Chunli Feng, Tanya M. Laidlaw, Pamela B. Conley, Yoshihide Kanaoka, Joshua A. Boyce

J Immunol. Author manuscript; available in PMC 2014 Dec 15.

Published in final edited form as: J Immunol. 2013 Dec 15; 191(12): 10.4049/jimmunol.1302187. Published online 2013 Nov 15. doi: 10.4049/jimmunol.1302187