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Select item 94706751.

Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation

Ting Gao, Lin Zhu, Hainan Liu, Xiaopeng Zhang, Tingting Wang, Yangbo Fu, Hongzhen Li, Qincai Dong, Yong Hu, Zhang Zhang, Jing Jin, Zijing Liu, Weihong Yang, Yaoning Liu, Yanwen Jin, Kaitong Li, Yongjiu Xiao, Junli Liu, Huailong Zhao, Yue Liu, Ping Li, Jibo Song, Lu Zhang, Yuwei Gao, Sisi Kang, Shoudeng Chen, Qingjun Ma, Xiuwu Bian, Wei Chen, Xuan Liu, Qing Mao, Cheng Cao

Signal Transduct Target Ther. 2022; 7: 318. Published online 2022 Sep 14. doi: 10.1038/s41392-022-01133-5

PMCID:: PMC9470675

Abstract Article PDF–6.1M

Select item 69443892.

Herpes simplex encephalitis in adult patients with MASP-2 deficiency

Stéphanie Bibert, Jocelyne Piret, Mathieu Quinodoz, Emilie Collinet, Vincent Zoete, Olivier Michielin, Rafik Menasria, Pascal Meylan, Titus Bihl, Véronique Erard, Florence Fellmann, Carlo Rivolta, Guy Boivin, Pierre-Yves Bochud

PLoS Pathog. 2019 Dec; 15(12): e1008168. Published online 2019 Dec 23. doi: 10.1371/journal.ppat.1008168

PMCID:: PMC6944389

Abstract Article PDF–2.4M

Select item 67681263.

Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury

Samy Alghadban, Hany I. Kenawy, Thomas Dudler, Wilhelm J. Schwaeble, Nigel J. Brunskill

Front Immunol. 2019; 10: 2238. Published online 2019 Sep 23. doi: 10.3389/fimmu.2019.02238

PMCID:: PMC6768126

Abstract Article PDF–1.6M

Select item 55684864.

Deconstructing the lectin pathway in the pathogenesis of experimental inflammatory arthritis: essential role of the lectin ficolin B and mannose-binding protein-associated serine protease 2

Nirmal K. Banda, Sumitra Acharya, Robert I. Scheinman, Gaurav Mehta, Minoru Takahashi, Yuichi Endo, Wuding Zhou, Conrad A. Farrar, Steven H. Sacks, Teijo Fujita, Hideharu Sekine, V. Michael Holers

J Immunol. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: J Immunol. 2017 Sep 1; 199(5): 1835–1845. Published online 2017 Jul 24. doi: 10.4049/jimmunol.1700119

PMCID:: PMC5568486

Abstract Article PDF–1.2M

Select item 54185805.

Developmental activities of the complement pathway in migrating neurons

Anna Gorelik, Tamar Sapir, Rebecca Haffner-Krausz, Tsviya Olender, Trent M. Woodruff, Orly Reiner

Nat Commun. 2017; 8: 15096. Published online 2017 May 2. doi: 10.1038/ncomms15096

PMCID:: PMC5418580

Abstract Article PDF–4.5M

Select item 51848426.

Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4

Elham Asgari, Conrad A. Farrar, Nicholas Lynch, Youssif M. Ali, Silke Roscher, Cordula Stover, Wuding Zhou, Wilhelm J. Schwaeble, Steven H. Sacks

FASEB J. 2014 Sep; 28(9): 3996–4003. doi: 10.1096/fj.13-246306

PMCID:: PMC5184842

Abstract Article

Select item 50066107.

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1

Franca Orsini, Elvina Chrysanthou, Thomas Dudler, W. Jason Cummings, Minoru Takahashi, Teizo Fujita, Gregory Demopulos, Maria-Grazia De Simoni, Wilhelm Schwaeble

J Neuroinflammation. 2016; 13(1): 213. Published online 2016 Aug 30. doi: 10.1186/s12974-016-0684-6

PMCID:: PMC5006610

Abstract Article PDF–1.7M

Select item 49963388.

Experimentally‐induced anti‐myeloperoxidase vasculitis does not require properdin, MASP‐2 or bone marrow‐derived C5

Simon J Freeley, Reena J Popat, Kiran Parmar, Martin Kolev, Beverley J Hunt, Cordula M Stover, Willhelm Schwaeble, Claudia Kemper, Michael G Robson

J Pathol. 2016 Sep; 240(1): 61–71. Published online 2016 Aug 22. doi: 10.1002/path.4754

Correction in:: J Pathol. 2021 May; 254(1): 103.

PMCID:: PMC4996338

Abstract Article PDF–5.3M

Select item 48559249.

Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury

Conrad A. Farrar, David Tran, Ke Li, Weiju Wu, Qi Peng, Wilhelm Schwaeble, Wuding Zhou, Steven H. Sacks

J Clin Invest. 2016 May 2; 126(5): 1911–1925. Published online 2016 Apr 18. doi: 10.1172/JCI83000

PMCID:: PMC4855924

Abstract Article PDF–7.2M

Select item 398929910.

Gene Targeting of Mouse Tardbp Negatively Affects Masp2 Expression

Samar Dib, Shangxi Xiao, Denise Miletic, Janice Robertson

PLoS One. 2014; 9(4): e95373. Published online 2014 Apr 16. doi: 10.1371/journal.pone.0095373

PMCID:: PMC3989299

Abstract Article PDF–410K

Select item 386144011.

Human L-ficolin, a Recognition Molecule of the Lectin Activation Pathway of Complement, Activates Complement by Binding to Pneumolysin, the Major Toxin of Streptococcus pneumoniae

Youssif M. Ali, Hany I. Kenawy, Adnan Muhammad, Robert B. Sim, Peter W. Andrew, Wilhelm J. Schwaeble

PLoS One. 2013; 8(12): e82583. Published online 2013 Dec 12. doi: 10.1371/journal.pone.0082583

PMCID:: PMC3861440

Abstract Article PDF–495K

Select item 339040512.

The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

Youssif M. Ali, Nicholas J. Lynch, Kashif S. Haleem, Teizo Fujita, Yuichi Endo, Soren Hansen, Uffe Holmskov, Kazue Takahashi, Gregory L. Stahl, Thomas Dudler, Umakhanth V. Girija, Russell Wallis, Aras Kadioglu, Cordula M. Stover, Peter W. Andrew, Wilhelm J. Schwaeble

PLoS Pathog. 2012 Jul; 8(7): e1002793. Published online 2012 Jul 5. doi: 10.1371/journal.ppat.1002793

PMCID:: PMC3390405

Abstract Article PDF–1006K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 308859914.

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

Wilhelm J. Schwaeble, Nicholas J. Lynch, James E. Clark, Michael Marber, Nilesh J. Samani, Youssif Mohammed Ali, Thomas Dudler, Brian Parent, Karl Lhotta, Russell Wallis, Conrad A. Farrar, Steven Sacks, Haekyung Lee, Ming Zhang, Daisuke Iwaki, Minoru Takahashi, Teizo Fujita, Clark E. Tedford, Cordula M. Stover

Proc Natl Acad Sci U S A. 2011 May 3; 108(18): 7523–7528. Published online 2011 Apr 18. doi: 10.1073/pnas.1101748108

PMCID:: PMC3088599

Abstract Article PDF–472K

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 281254116.

Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D

Minoru Takahashi, Yumi Ishida, Daisuke Iwaki, Kazuko Kanno, Toshiyuki Suzuki, Yuichi Endo, Yoshimi Homma, Teizo Fujita

J Exp Med. 2010 Jan 18; 207(1): 29–37. doi: 10.1084/jem.20090633

PMCID:: PMC2812541

Abstract Article PDF–2.3M

Select item 255627017.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 141356818.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 52892819.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 31099220.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

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