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Items: 1 to 20 of 204

1.
The aged microenvironment impairs BCL6 and CD40L induction in CD4+ T follicular helper cell differentiation
Jacob S. Fisher, Irene Adán‐Barrientos, Naveen R. Kumar, Jessica N. Lancaster
Aging Cell. 2024 Jun; 23(6): e14140. Published online 2024 Mar 13. doi: 10.1111/acel.14140
PMCID:
PMC11296098
AbstractArticlePDF–10M
2.
B cells in the pneumococcus-infected lung are heterogeneous and require CD4+ T cell help including CD40L to become resident memory B cells
Neelou S. Etesami, Kimberly A. Barker, Anukul T. Shenoy, Carolina Lyon De Ana, Emad I. Arafa, Gabrielle N. Grifno, Adeline M. Matschulat, Michael E. Vannini, Riley M. F. Pihl, Michael P. Breen, Alicia M. Soucy, Wesley N. Goltry, Catherine T. Ha, Hanae Betsuyaku, Jeffrey L. Browning, Xaralabos Varelas, Katrina E. Traber, Matthew R. Jones, Lee J. Quinton, Paul J. Maglione, Hadi T. Nia, Anna C. Belkina, Joseph P. Mizgerd
Front Immunol. 2024; 15: 1382638. Published online 2024 Apr 23. doi: 10.3389/fimmu.2024.1382638
PMCID:
PMC11074383
AbstractArticlePDF–4.3M
3.
Linkage of CD40L to a self-tumor antigen enhances the antitumor immune responses of dendritic cell-based treatment
Hsin-Wei Chen, Hsing-I Huang, Yi-Ping Lee, Li-Li Chen, Hsiung-Kun Liu, Mei-Lien Cheng, Jy-Ping Tsai, Mi-Hua Tao, Chou-Chik Ting
Cancer Immunol Immunother. 2002 Aug; 51(6): 341–348. Published online 2002 Jun 14. doi: 10.1007/s00262-002-0283-5
PMCID:
PMC11032834
AbstractArticlePDF–198K
4.
Immune synapse formation promotes lipid peroxidation and MHC-I upregulation in licensed dendritic cells for efficient priming of CD8+ T cells
Diego Calzada-Fraile, Salvador Iborra, Marta Ramírez-Huesca, Inmaculada Jorge, Enrico Dotta, Elena Hernández-García, Noa Martín-Cófreces, Estanislao Nistal-Villán, Esteban Veiga, Jesús Vázquez, Giulia Pasqual, Francisco Sánchez-Madrid
Nat Commun. 2023; 14: 6772. Published online 2023 Oct 25. doi: 10.1038/s41467-023-42480-3
PMCID:
PMC10600134
AbstractArticlePDF–2.0M
5.
Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help
Terry R. Medler, Gwen Kramer, Shelly Bambina, Andrew J. Gunderson, Alejandro Alice, Tiffany Blair, Lauren Zebertavage, Thomas Duhen, Rebekka Duhen, Kristina Young, Marka R. Crittenden, Michael J. Gough
Sci Rep. 2023; 13: 6277. Published online 2023 Apr 18. doi: 10.1038/s41598-023-33508-1
PMCID:
PMC10113239
AbstractArticlePDF–2.3M
6.
BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen
Yu Xia, Katalin Sandor, Joy A. Pai, Bence Daniel, Saravanan Raju, Renee Wu, Sunnie Hsiung, Yanyan Qi, Tenzin Yangdon, Mariko Okamoto, Chun Chou, Kamir J. Hiam-Galvez, Robert D. Schreiber, Kenneth M. Murphy, Ansuman T. Satpathy, Takeshi Egawa
Immunity. Author manuscript; available in PMC 2023 Jul 12.
Published in final edited form as: Immunity. 2022 Jul 12; 55(7): 1200–1215.e6. Published online 2022 May 27. doi: 10.1016/j.immuni.2022.05.003
PMCID:
PMC10034764
AbstractArticlePDF–3.3M
7.
Chronic CD40L blockade is required for long-term cardiac allograft survival with a clinically relevant CTLA4-Ig dosing regimen
Lukas W. Unger, Moritz Muckenhuber, Benedikt Mahr, Christoph Schwarz, Nina Pilat, Nicolas Granofszky, Heinz Regele, Thomas Wekerle
Front Immunol. 2022; 13: 1060576. Published online 2022 Dec 8. doi: 10.3389/fimmu.2022.1060576
PMCID:
PMC9773869
AbstractArticlePDF–2.6M
8.
Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD
Chi Ma, Qiong Fu, Laurence P. Diggs, John C. McVey, Justin McCallen, Simon Wabitsch, Benjamin Ruf, Zachary Brown, Bernd Heinrich, Qianfei Zhang, Umberto Rosato, Sophie Wang, Linda Cui, Jay A. Berzofsky, David E. Kleiner, Dale B. Bosco, Long-Jun Wu, Chunwei Walter Lai, Yaron Rotman, Changqing Xie, Firouzeh Korangy, Tim F. Greten
Cancer Cell. Author manuscript; available in PMC 2023 Sep 12.
Published in final edited form as: Cancer Cell. 2022 Sep 12; 40(9): 986–998.e5. Published online 2022 Sep 1. doi: 10.1016/j.ccell.2022.08.004
PMCID:
PMC9474605
AbstractArticlePDF–2.3M
9.
Synergistic antitumor response with recombinant modified virus Ankara armed with CD40L and CD137L against peritoneal carcinomatosis
Ángela Bella, Leire Arrizabalaga, Claudia Augusta Di Trani, Assunta Cirella, Myriam Fernandez-Sendin, Celia Gomar, Joan Salvador Russo-Cabrera, Inmaculada Rodríguez, José González-Gomariz, Maite Alvarez, Álvaro Teijeira, José Medina-Echeverz, Maria Hinterberger, Hubertus Hochrein, Ignacio Melero, Pedro Berraondo, Fernando Aranda
Oncoimmunology. 2022; 11(1): 2098657. Published online 2022 Jul 13. doi: 10.1080/2162402X.2022.2098657
PMCID:
PMC9291657
AbstractArticlePDF–5.3M
10.
Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells
Attya Omer-Javed, Gabriele Pedrazzani, Luisa Albano, Sherash Ghaus, Claire Latroche, Maura Manzi, Samuele Ferrari, Martina Fiumara, Aurelien Jacob, Valentina Vavassori, Alessandro Nonis, Daniele Canarutto, Luigi Naldini
Cell. 2022 Jun 23; 185(13): 2248–2264.e21. doi: 10.1016/j.cell.2022.04.039
PMCID:
PMC9240327
AbstractArticle
11.
3-hydroxy butyrate dehydrogenase 2 deficiency aggravates systemic lupus erythematosus progression in a mouse model by promoting CD40 ligand demethylation
Bo Yang, Shihao Hou, Jingjing Zhao, Yepeng Li
Bioengineered. 2022; 13(2): 2685–2695. Published online 2022 Jan 9. doi: 10.1080/21655979.2022.2025694
PMCID:
PMC8973909
AbstractArticlePDF–1.6M
12.
Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression
Colin Valet, Mélia Magnen, Longhui Qiu, Simon J. Cleary, Kristin M. Wang, Serena Ranucci, Elodie Grockowiak, Rafik Boudra, Catharina Conrad, Yurim Seo, Daniel R. Calabrese, John R. Greenland, Andrew D. Leavitt, Emmanuelle Passegué, Simón Méndez-Ferrer, Filip K. Swirski, Mark R. Looney
J Clin Invest. 2022 Apr 1; 132(7): e153920. Published online 2022 Apr 1. doi: 10.1172/JCI153920
PMCID:
PMC8970674
AbstractArticlePDF–11M
13.
Neoantigen driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses
Can Cui, Jiawei Wang, Eric Fagerberg, Ping-Min Chen, Kelli A. Connolly, Martina Damo, Julie F. Cheung, Tianyang Mao, Adnan S. Askari, Shuting Chen, Brittany Fitzgerald, Gena G. Foster, Stephanie C. Eisenbarth, Hongyu Zhao, Joseph Craft, Nikhil S. Joshi
Cell. Author manuscript; available in PMC 2022 Dec 9.
Published in final edited form as: Cell. 2021 Dec 9; 184(25): 6101–6118.e13. Published online 2021 Nov 30. doi: 10.1016/j.cell.2021.11.007
PMCID:
PMC8671355
AbstractArticlePDF–1.5M
14.
A Posttranscriptional pathway of CD40L mRNA Stability is Required for the Development of an Optimal Humoral Immune Response
Bitha Narayanan, Diego Prado de Maio, James La Porta, Yekaterina Voskoboynik, Usha Ganapathi, Ping Xie, Lori R. Covey
J Immunol. Author manuscript; available in PMC 2022 Jun 1.
Published in final edited form as: J Immunol. 2021 Jun 1; 206(11): 2552–2565. Published online 2021 May 24. doi: 10.4049/jimmunol.2001074
PMCID:
PMC8543757
AbstractArticlePDF–3.3M
15.
CD40L modulates transcriptional signatures of neutrophils in the bone marrow associated with development and trafficking
Tábata Takahashi França, Ashraf Al-Sbiei, Ghada Bashir, Yassir Awad Mohamed, Ranieri Coelho Salgado, Lucila Akune Barreiros, Sarah Maria da Silva Napoleão, Cristina Worm Weber, Janaíra Fernandes Severo Ferreira, Carolina Sanchez Aranda, Carolina Prando, Mayra B. de Barros Dorna, Igor Jurisica, Maria J. Fernandez-Cabezudo, Hans D. Ochs, Antonio Condino-Neto, Basel K. Al-Ramadi, Otavio Cabral-Marques
JCI Insight. 2021 Aug 23; 6(16): e148652. Published online 2021 Aug 23. doi: 10.1172/jci.insight.148652
PMCID:
PMC8410015
AbstractArticlePDF–15M
16.
Downregulation of CD40L–CD40 attenuates seizure susceptibility and severity of seizures
Esther Pototskiy, Katherine Vinokuroff, Andrew Ojeda, C. Kendall Major, Deepak Sharma, Taylor Anderson, Kendall Howard, Ronen Borenstein, Alberto E. Musto
Sci Rep. 2021; 11: 17262. Published online 2021 Aug 26. doi: 10.1038/s41598-021-96760-3
Correction in:
Sci Rep. 2021; 11: 23252.
PMCID:
PMC8390750
AbstractArticlePDF–2.9M
17.
Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
Michael Lacy, Christina Bürger, Annelie Shami, Maiwand Ahmadsei, Holger Winkels, Katrin Nitz, Claudia M. van Tiel, Tom T. P. Seijkens, Pascal J. H. Kusters, Ela Karshovka, Koen H. M. Prange, Yuting Wu, Sanne L. N. Brouns, Sigrid Unterlugauer, Marijke J. E. Kuijpers, Myrthe E. Reiche, Sabine Steffens, Andreas Edsfeldt, Remco T. A. Megens, Johan W. M. Heemskerk, Isabel Goncalves, Christian Weber, Norbert Gerdes, Dorothee Atzler, Esther Lutgens
Nat Commun. 2021; 12: 3754. Published online 2021 Jun 18. doi: 10.1038/s41467-021-23909-z
PMCID:
PMC8213756
AbstractArticlePDF–3.6M
18.
NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting
Corey Tan, Ryosuke Hiwa, James L. Mueller, Vivasvan Vykunta, Kenta Hibiya, Mark Noviski, John Huizar, Jeremy F. Brooks, Jose Garcia, Cheryl Heyn, Zhongmei Li, Alexander Marson, Julie Zikherman
Nat Immunol. Author manuscript; available in PMC 2021 Apr 28.
Published in final edited form as: Nat Immunol. 2020 Oct; 21(10): 1267–1279. Published online 2020 Aug 31. doi: 10.1038/s41590-020-0765-7
PMCID:
PMC8081071
AbstractArticlePDF–5.3M
19.
Signalling Pathways Mediating the Effects of CD40-Activated CD40L Reverse Signalling on Inhibitory Medium Spiny Neuron Neurite Growth
Paulina Carriba, Alun M. Davies
Cells. 2021 Apr; 10(4): 829. Published online 2021 Apr 7. doi: 10.3390/cells10040829
PMCID:
PMC8067729
AbstractArticlePDF–6.3M
20.
CD40 signaling augments IL-10 expression and the tolerogenicity of IL-10-induced regulatory dendritic cells
Wojciech Dawicki, Hui Huang, Yanna Ma, Jennifer Town, Xiaobei Zhang, Chris D. Rudulier, John R. Gordon
PLoS One. 2021; 16(4): e0248290. Published online 2021 Apr 1. doi: 10.1371/journal.pone.0248290
PMCID:
PMC8016274
AbstractArticlePDF–1.9M

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