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Select item 114641271.

Age‐dependent heat shock hormesis to HSF‐1 deficiency suggests a compensatory mechanism mediated by the unfolded protein response and innate immunity in young Caenorhabditis elegans

Dániel Kovács, János Barnabás Biró, Saqib Ahmed, Márton Kovács, Tímea Sigmond, Bernadette Hotzi, Máté Varga, Viktor Vázsony Vincze, Umar Mohammad, Tibor Vellai, János Barna

Aging Cell. 2024 Oct; 23(10): e14246. Published online 2024 Jun 19. doi: 10.1111/acel.14246

PMCID:: PMC11464127

Abstract Article PDF–1.9M

Select item 112584802.

Combinatorial transcriptomic and genetic dissection of insulin/IGF‐1 signaling‐regulated longevity in Caenorhabditis elegans

Seokjin Ham, Sieun S. Kim, Sangsoon Park, Hyunwoo C. Kwon, Seokjun G. Ha, Yunkyu Bae, Gee‐Yoon Lee, Seung‐Jae V. Lee

Aging Cell. 2024 Jul; 23(7): e14151. Published online 2024 Mar 26. doi: 10.1111/acel.14151

PMCID:: PMC11258480

Abstract Article PDF–1.4M

Select item 112161683.

Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues

Ambre J. Sala, Rogan A. Grant, Ghania Imran, Claire Morton, Renee M. Brielmann, Szymon Gorgoń, Jennifer Watts, Laura C. Bott, Richard I. Morimoto

Genes Dev. 2024 May 1; 38(9-10): 380–392. doi: 10.1101/gad.351829.124

PMCID:: PMC11216168

Abstract Article PDF–4.5M

Select item 111574844.

2-Butoxytetrahydrofuran, Isolated from Holothuria scabra, Attenuates Aggregative and Oxidative Properties of α-Synuclein and Alleviates Its Toxicity in a Transgenic Caenorhabditis elegans Model of Parkinson’s Disease

Sukrit Promtang, Tanatcha Sanguanphun, Pawanrat Chalorak, Laurence S. Pe, Nakorn Niamnont, Prasert Sobhon, Krai Meemon

ACS Chem Neurosci. 2024 Jun 5; 15(11): 2182–2197. Published online 2024 May 10. doi: 10.1021/acschemneuro.4c00008

PMCID:: PMC11157484

Abstract Article PDF–8.0M

Select item 111124835.

Mitochondrial clearance and increased HSF-1 activity are coupled to promote longevity in fasted Caenorhabditis elegans

Nikolaos Tataridas-Pallas, Yahyah Aman, Rhianna Williams, Hannah Chapman, Kevin J.H. Cheng, Casandra Gomez-Paredes, Gillian P. Bates, John Labbadia

iScience. 2024 Jun 21; 27(6): 109834. Published online 2024 Apr 27. doi: 10.1016/j.isci.2024.109834

PMCID:: PMC11112483

Abstract Article PDF–5.1M

Select item 110043426.

Phloretic acid requires the insulin/IGF-1 pathway and autophagy to enhance stress resistance and extend the lifespan of Caenorhabditis elegans

Bo Li, Li Dong, Wei Meng, Shi-Ying Xiong, Gui-Sheng Wu, Wen-Zhe Ma, Huai-Rong Luo

Front Pharmacol. 2024; 15: 1384227. Published online 2024 Mar 27. doi: 10.3389/fphar.2024.1384227

PMCID:: PMC11004342

Abstract Article PDF–3.0M

Select item 108692777.

SKN-1 is indispensable for protection against Aβ-induced proteotoxicity by a selenopeptide derived from Cordyceps militaris

Mengfei Chen, Zhenjun Zhu, Shujian Wu, Aohuan Huang, Zhiqing Xie, Jie Cai, Rong Huang, Shubo Yu, Ming Liu, Jumei Zhang, Yuchung Tse, Qingping Wu, Juan Wang, Yu Ding

Redox Biol. 2024 Apr; 70: 103065. Published online 2024 Feb 5. doi: 10.1016/j.redox.2024.103065

PMCID:: PMC10869277

Abstract Article PDF–4.2M

Select item 108504888.

Magnolol extends lifespan and improves age-related neurodegeneration in Caenorhabditis elegans via increase of stress resistance

Jing Yu, Xiaoyan Gao, Lijun Zhang, Hang Shi, Yingxuan Yan, Yongli Han, Chengyuan Wu, Ying Liu, Minglv Fang, Cheng Huang, Shengjie Fan

Sci Rep. 2024; 14: 3158. Published online 2024 Feb 7. doi: 10.1038/s41598-024-53374-9

PMCID:: PMC10850488

Abstract Article PDF–6.3M

Select item 108078099.

Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin

Wei I. Jiang, Henry De Belly, Bingying Wang, Andrew Wong, Minseo Kim, Fiona Oh, Jason DeGeorge, Xinya Huang, Shouhong Guang, Orion D. Weiner, Dengke K. Ma

Sci Adv. 2024 Jan 26; 10(4): eadj3880. Published online 2024 Jan 24. doi: 10.1126/sciadv.adj3880

PMCID:: PMC10807809

Abstract Article PDF–6.7M

Select item 1076353810.

Diversification of small RNA pathways underlies germline RNA interference incompetence in wild Caenorhabditis elegans strains

Han Ting Chou, Francisco Valencia, Jacqueline C Alexander, Avery Davis Bell, Diptodip Deb, Daniel A Pollard, Annalise B Paaby

Genetics. 2024 Jan; 226(1): iyad191. Published online 2023 Oct 22. doi: 10.1093/genetics/iyad191

PMCID:: PMC10763538

Abstract Article PDF–1.9M

Select item 1058168711.

Proteostasis is differentially modulated by inhibition of translation initiation or elongation

Khalyd J Clay, Yongzhi Yang, Christina Clark, Michael Petrascheck

eLife. 2023; 12: e76465. Published online 2023 Oct 5. doi: 10.7554/eLife.76465

PMCID:: PMC10581687

Abstract Article PDF–3.7M

Select item 1055091712.

Lactobacillus paracasei HII01 enhances lifespan and promotes neuroprotection in Caenorhabditis elegans

Kishoree K. Kumaree, Mani Iyer Prasanth, Bhagavathi Sundaram Sivamaruthi, Periyanaina Kesika, Tewin Tencomnao, Chaiyavat Chaiyasut, Anchalee Prasansuklab

Sci Rep. 2023; 13: 16707. Published online 2023 Oct 4. doi: 10.1038/s41598-023-43846-9

PMCID:: PMC10550917

Abstract Article PDF–1.6M

Select item 1052810513.

A novel endoplasmic reticulum adaptation is critical for the longlived Caenorhabditis elegans rpn-10 proteasomal mutant

Meghna N. Chinchankar, William B. Taylor, Su-Hyuk Ko, Ellen C. Apple, Karl A. Rodriguez, Lizhen Chen, Alfred L. Fisher

Biochim Biophys Acta Gene Regul Mech. Author manuscript; available in PMC 2024 Sep 1.

Published in final edited form as: Biochim Biophys Acta Gene Regul Mech. 2023 Sep; 1866(3): 194957. Published online 2023 Jun 22. doi: 10.1016/j.bbagrm.2023.194957

PMCID:: PMC10528105

Abstract Article PDF–2.4M

Select item 1044821214.

Preparation of low molecular weight polysaccharides from Tremella fuciformis by ultrasonic-assisted H₂O₂-Vc method: Structural characteristics, in vivo antioxidant activity and stress resistance

Quancen Lee, Xianjing Han, Mingfeng Zheng, Feng Lv, Bin Liu, Feng Zeng

Ultrason Sonochem. 2023 Oct; 99: 106555. Published online 2023 Aug 9. doi: 10.1016/j.ultsonch.2023.106555

PMCID:: PMC10448212

Abstract Article PDF–3.2M

Select item 1035360715.

Lycium barbarum glycopetide prolong lifespan and alleviate Parkinson’s disease in Caenorhabditis elegans

Jingming Zheng, Zhenhuan Luo, Kin Chiu, Yimin Li, Jing Yang, Qinghua Zhou, Kwok-Fai So, Qin-Li Wan

Front Aging Neurosci. 2023; 15: 1156265. Published online 2023 Jul 4. doi: 10.3389/fnagi.2023.1156265

PMCID:: PMC10353607

Abstract Article PDF–3.2M

Select item 1034509016.

Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans

Fan Xu, Ruoyao Li, Erika D. von Gromoff, Friedel Drepper, Bettina Knapp, Bettina Warscheid, Ralf Baumeister, Wenjing Qi

Nat Commun. 2023; 14: 4176. Published online 2023 Jul 13. doi: 10.1038/s41467-023-39882-8

PMCID:: PMC10345090

Abstract Article PDF–8.1M

Select item 1032052417.

A proton-inhibited DEG/ENaC ion channel maintains neuronal ionstasis and promotes neuronal survival under stress

Dionysia Petratou, Martha Gjikolaj, Eva Kaulich, William Schafer, Nektarios Tavernarakis

iScience. 2023 Jul 21; 26(7): 107117. Published online 2023 Jun 14. doi: 10.1016/j.isci.2023.107117

PMCID:: PMC10320524

Abstract Article PDF–8.3M

Select item 1028773818.

Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response

Eunah Kim, Andrea Annibal, Yujin Lee, Hae-Eun H. Park, Seokjin Ham, Dae-Eun Jeong, Younghun Kim, Sangsoon Park, Sujeong Kwon, Yoonji Jung, JiSoo Park, Sieun S. Kim, Adam Antebi, Seung-Jae V. Lee

Nat Commun. 2023; 14: 3716. Published online 2023 Jun 22. doi: 10.1038/s41467-023-39393-6