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Select item 111831181.

Mime-seq 2.0: a method to sequence microRNAs from specific mouse cell types

Ariane Mandlbauer, Qiong Sun, Niko Popitsch, Tanja Schwickert, Miroslava Spanova, Jingkui Wang, Stefan L Ameres, Meinrad Busslinger, Luisa Cochella

EMBO J. 2024 Jun; 43(12): 2506–2525. Published online 2024 Apr 30. doi: 10.1038/s44318-024-00102-8

PMCID:: PMC11183118

Abstract Article PDF–7.2M

Select item 110812242.

ΔNp63 regulates Sfrp1 expression to direct salivary gland branching morphogenesis

Theresa Wrynn, Sangwon Min, Erich Horeth, Jason Osinski, Satrajit Sinha, Rose-Anne Romano

PLoS One. 2024; 19(5): e0301082. Published online 2024 May 9. doi: 10.1371/journal.pone.0301082

PMCID:: PMC11081224

Abstract Article PDF–7.0M

Select item 107434763.

Loss of Cdc42 in Exocrine Acini Decreases Saliva Secretion but Increases Tear Secretion—A Potential Model of Exocrine Gland Senescence

Haruna Nagase, Akiko Shitara, Yuta Ohno, Keitaro Satoh, Masanori Kashimata

Int J Mol Sci. 2023 Dec; 24(24): 17220. Published online 2023 Dec 7. doi: 10.3390/ijms242417220

PMCID:: PMC10743476

Abstract Article PDF–12M

Select item 105768114.

FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation

Marit H. Aure, Jennifer M. Symonds, Carlos U. Villapudua, Joshua T. Dodge, Sabine Werner, Wendy M. Knosp, Matthew P. Hoffman

Nat Commun. 2023; 14: 6485. Published online 2023 Oct 14. doi: 10.1038/s41467-023-42243-0

PMCID:: PMC10576811

Abstract Article PDF–17M

Select item 104147545.

Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis

Zhengyu Jiang, Feijing Wu, Pasquale Laise, Tanaka Takayuki, Fu Na, Woosook Kim, Hiroki Kobayashi, Wenju Chang, Ryota Takahashi, Giovanni Valenti, Masaki Sunagawa, Ruth A. White, Marina Macchini, Bernhard W. Renz, Moritz Middelhoff, Yoku Hayakawa, Zinaida Dubeykovskaya, Xiangtian Tan, Timothy Chu, Karan Nagar, Yagnesh Tailor, Bryana R Belin, Akanksha Anand, Samuel Asfaha, Michael O Finlayson, Alina C Iuga, Andrea Califano, Timothy C Wang

Cell Stem Cell. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: Cell Stem Cell. 2023 Aug 3; 30(8): 1091–1109.e7. doi: 10.1016/j.stem.2023.07.002

PMCID:: PMC10414754

Abstract Article PDF–5.0M

Select item 102567246.

Inflationary theory of branching morphogenesis in the mouse salivary gland

Ignacio Bordeu, Lemonia Chatzeli, Benjamin D. Simons

Nat Commun. 2023; 14: 3422. Published online 2023 Jun 9. doi: 10.1038/s41467-023-39124-x

PMCID:: PMC10256724

Abstract Article PDF–4.2M

Select item 98113527.

The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells

Miriam Wöhner, Theresa Pinter, Peter Bönelt, Astrid Hagelkruys, Daniela Kostanova-Poliakova, Johannes Stadlmann, Stephen F. Konieczny, Maria Fischer, Markus Jaritz, Meinrad Busslinger

Front Immunol. 2022; 13: 859598. Published online 2022 Dec 21. doi: 10.3389/fimmu.2022.859598

PMCID:: PMC9811352

Abstract Article PDF–14M

Select item 97088208.

FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells

Matthew R. Jones, Arun Lingampally, Negah Ahmadvand, Lei Chong, Jin Wu, Jochen Wilhem, Ana Ivonne Vazquez-Armendariz, Meshal Ansari, Susanne Herold, David M. Ornitz, Herbert B. Schiller, Cho-Ming Chao, Jin-San Zhang, Gianni Carraro, Saverio Bellusci

Cell Mol Life Sci. 2022; 79(12): 609. Published online 2022 Nov 29. doi: 10.1007/s00018-022-04626-2

PMCID:: PMC9708820

Abstract Article PDF–3.1M

Select item 83525889.

Highly localized intracellular Ca²⁺ signals promote optimal salivary gland fluid secretion

Takahiro Takano, Amanda M Wahl, Kai-Ting Huang, Takanori Narita, John Rugis, James Sneyd, David I Yule

eLife. 2021; 10: e66170. Published online 2021 Jul 9. doi: 10.7554/eLife.66170

PMCID:: PMC8352588

Abstract Article PDF–15M

Select item 825156210.

Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease

Evans Quilichini, Mélanie Fabre, Christoffer Nord, Thassadite Dirami, Axelle Le Marec, Silvia Cereghini, Raymond C Pasek, Maureen Gannon, Ulf Ahlgren, Cécile Haumaitre

J Pathol. 2021 May; 254(1): 31–45. Published online 2021 Mar 18. doi: 10.1002/path.5629

PMCID:: PMC8251562

Abstract Article PDF–46M

Select item 803438311.

Uncovering the dosage-dependent roles of Arid1a in gastric tumorigenesis for combinatorial drug therapy

Adrian Kwan Ho Loe, Roshane Francis, Jieun Seo, Lutao Du, Yunshan Wang, Ji-Eun Kim, Shaheed W. Hakim, Jung-Eun Kim, Housheng Hansen He, Haiyang Guo, Tae-Hee Kim

J Exp Med. 2021 Jun 7; 218(6): e20200219. Published online 2021 Apr 5. doi: 10.1084/jem.20200219

PMCID:: PMC8034383

Abstract Article PDF–10M

Select item 801063612.

Trop2 is Upregulated in the Transition to Dysplasia in the Metaplastic Gastric Mucosa

Katherine M. Riera, Bogun Jang, Jimin Min, Joseph T. Roland, Qing Yang, William T. Fesmire, Sophie Camilleri-Broet, Lorenzo Ferri, Woo Ho Kim, Eunyoung Choi, James R. Goldenring

J Pathol. Author manuscript; available in PMC 2021 Mar 31.

Published in final edited form as: J Pathol. 2020 Jul; 251(3): 336–347. Published online 2020 Jun 15. doi: 10.1002/path.5469

PMCID:: PMC8010636

Abstract Article PDF–2.4M

Select item 776819713.

Sustained Helicobacter pylori infection accelerates gastric dysplasia in a mouse model

Valerie P O’Brien, Amanda L Koehne, Julien Dubrulle, Armando E Rodriguez, Christina K Leverich, V Paul Kong, Jean S Campbell, Robert H Pierce, James R Goldenring, Eunyoung Choi, Nina R Salama

Life Sci Alliance. 2021 Feb; 4(2): e202000967. Published online 2020 Dec 11. doi: 10.26508/lsa.202000967

PMCID:: PMC7768197

Abstract Article PDF–5.5M

Select item 771848814.

Generation of a Single-Cell RNAseq Atlas of Murine Salivary Gland Development

Belinda R. Hauser, Marit H. Aure, Michael C. Kelly, Genomics and Computational Biology Core, Matthew P. Hoffman, Alejandro M. Chibly

iScience. 2020 Dec 18; 23(12): 101838. Published online 2020 Nov 20. doi: 10.1016/j.isci.2020.101838

PMCID:: PMC7718488

Abstract Article PDF–37M

Select item 761488415.

A cellular hierarchy of Notch and Kras signaling controls cell fate specification in the developing mouse salivary gland

Lemonia Chatzeli, Ignacio Bordeu, Seungmin Han, Sara Bisetto, Zahra Waheed, Maria P. Alcolea, Benjamin D. Simons

Dev Cell. Author manuscript; available in PMC 2023 Aug 4.

Published in final edited form as: Dev Cell. 2023 Jan 23; 58(2): 94–109.e6. doi: 10.1016/j.devcel.2022.12.009

PMCID:: PMC7614884

Abstract Article PDF–3.4M

Select item 748317016.

Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis

Dakota N Jackson, Marina Panopoulos, William L Neumann, Kevin Turner, Brandi L Cantarel, LuAnn Thompson-Snipes, Themistocles Dassopoulos, Linda A Feagins, Rhonda F Souza, Jason C Mills, Richard S Blumberg, K Venuprasad, Winston E Thompson, Arianne L Theiss

Gut. 2020 Nov; 69(11): 1928–1938. Published online 2020 Feb 28. doi: 10.1136/gutjnl-2019-319523

PMCID:: PMC7483170

Abstract Article PDF–6.7M

Select item 703102817.

Early TP53 Alterations Engage Environmental Exposures to Promote Gastric Premalignancy in an Integrative Mouse Model

Nilay S. Sethi, Osamu Kikuchi, Gina Duronio, Matthew D. Stachler, James M. McFarland, Ruben Ferrer-Luna, Yanxi Zhang, Chunyang Bao, Roderick Bronson, Deepa Patil, Francisco Sanchez-Vega, Jie-Bin Liu, Ewa Sicinska, Jean-Bernard Lazaro, Keith L. Ligon, Rameen Beroukhim, Adam J. Bass

Nat Genet. Author manuscript; available in PMC 2020 Aug 5.

Published in final edited form as: Nat Genet. 2020 Feb; 52(2): 219–230. Published online 2020 Feb 5. doi: 10.1038/s41588-019-0574-9

PMCID:: PMC7031028

Abstract Article PDF–4.8M

Select item 700738318.

Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer

Haisheng Zhang, Antje Schaefer, Yichen Wang, Richard G. Hodge, Devon R. Blake, J. Nathaniel Diehl, Alex G. Papageorge, Matthew Stachler, Jennifer Liao, Jin Zhou, Zhong Wu, Fahire Akarca, Leonie K. de Klerk, Sarah Derks, Mariaelena Pierobon, Katherine A. Hoadley, Timothy C. Wang, George Church, Kwok-Kin Wong, Emanuel F. Petricoin, Adrienne D. Cox, Douglas R. Lowy, Channing J. Der, Adam J. Bass

Cancer Discov. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Cancer Discov. 2020 Feb; 10(2): 288–305. Published online 2019 Nov 26. doi: 10.1158/2159-8290.CD-19-0811

PMCID:: PMC7007383

Abstract Article PDF–3.8M

Select item 694882819.

YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma

Bo Tu, Jun Yao, Sammy Ferri-Borgogno, Jun Zhao, Shujuan Chen, Qiuyun Wang, Liang Yan, Xin Zhou, Cihui Zhu, Seungmin Bang, Qing Chang, Christopher A. Bristow, Ya’an Kang, Hongwu Zheng, Huamin Wang, Jason B. Fleming, Michael Kim, Timothy P. Heffernan, Giulio F. Draetta, Duojia Pan, Anirban Maitra, Wantong Yao, Sonal Gupta, Haoqiang Ying

JCI Insight. 2019 Nov 1; 4(21): e130811. Published online 2019 Nov 1. doi: 10.1172/jci.insight.130811

PMCID:: PMC6948828

Abstract Article PDF–12M

Select item 688978920.

Mist1 Expression Is Required for Paneth Cell Maturation

Christopher M. Dekaney, Stephanie King, Breanna Sheahan, Jocsa E. Cortes

Cell Mol Gastroenterol Hepatol. 2019; 8(4): 549–560. Published online 2019 Jul 19. doi: 10.1016/j.jcmgh.2019.07.003

PMCID:: PMC6889789

Abstract Article PDF–3.7M

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