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Items: 1 to 20 of 46

1.
Ubiquitin ligases Siah1a/2 control alveolar macrophage functions to limit carcinogen-induced lung adenocarcinoma
Marzia Scortegagna, Yuanning Du, Linda M. Bradley, Kun Wang, Alfredo Molinolo, Eytan Ruppin, Rabi Murad, Ze’ev A. Ronai
Cancer Res. Author manuscript; available in PMC 2023 Dec 15.
Published in final edited form as: Cancer Res. 2023 Jun 15; 83(12): 2016–2033. doi: 10.1158/0008-5472.CAN-23-0258
PMCID:
PMC10330299
AbstractArticlePDF–2.6M
2.
“The ubiquitin ligase SIAH2 is a female-specific regulator of circadian rhythms and metabolism”
Tsedey Mekbib, Ting-Chung Suen, Aisha Rollins-Hairston, Kiandra Smith, Ariel Armstrong, Cloe Gray, Sharon Owino, Kenkichi Baba, Julie E. Baggs, J. Christopher Ehlen, Gianluca Tosini, Jason P. DeBruyne
PLoS Genet. 2022 Jul; 18(7): e1010305. Published online 2022 Jul 5. doi: 10.1371/journal.pgen.1010305
PMCID:
PMC9286287
AbstractArticlePDF–3.2M
3.
Siah2 is expressed in adipocyte precursor cells and interacts with EBF1 and ZFP521 to promote adipogenesis
Thanh N. Dang, Jessica L. Taylor, Gail Kilroy, Yongmei Yu, David H. Burk, Z. Elizabeth Floyd
Obesity (Silver Spring) Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: Obesity (Silver Spring). 2021 Jan; 29(1): 98–107. Published online 2020 Nov 6. doi: 10.1002/oby.23013
PMCID:
PMC7902405
AbstractArticlePDF–1.7M
4.
Siah2 integrates mitogenic and extracellular matrix signals linking neuronal progenitor ciliogenesis with germinal zone occupancy
Taren Ong, Niraj Trivedi, Randall Wakefield, Sharon Frase, David J. Solecki
Nat Commun. 2020; 11: 5312. Published online 2020 Oct 20. doi: 10.1038/s41467-020-19063-7
PMCID:
PMC7576183
AbstractArticlePDF–5.6M
5.
SIAH2-mediated and organ-specific restriction of HO-1 expression by a dual mechanism
Shashipavan Chillappagari, Ratnal Belapurkar, Andreas Möller, Nicole Molenda, Michael Kracht, Susanne Rohrbach, M. Lienhard Schmitz
Sci Rep. 2020; 10: 2268. Published online 2020 Feb 10. doi: 10.1038/s41598-020-59005-3
PMCID:
PMC7010731
AbstractArticlePDF–3.7M
6.
Siah2 control of T-regulatory cells limits anti-tumor immunity
Marzia Scortegagna, Kathryn Hockemeyer, Igor Dolgalev, Joanna Poźniak, Florian Rambow, Yan Li, Yongmei Feng, Roberto Tinoco, Dennis C. Otero, Tongwu Zhang, Kevin Brown, Marcus Bosenberg, Linda M. Bradley, Jean-Christophe Marine, Ioannis Aifantis, Ze’ev A. Ronai
Nat Commun. 2020; 11: 99. Published online 2020 Jan 7. doi: 10.1038/s41467-019-13826-7
PMCID:
PMC6946684
AbstractArticlePDF–3.8M
7.
Siah2 modulates sex-dependent metabolic and inflammatory responses in adipose tissue to a high-fat diet challenge
Sujoy Ghosh, Jessica L. Taylor, Tamra M. Mendoza, Thanh Dang, David H. Burk, Yongmei Yu, Gail Kilroy, Z. Elizabeth Floyd
Biol Sex Differ. 2019; 10: 19. Published online 2019 Apr 15. doi: 10.1186/s13293-019-0233-y
Correction in:
Biol Sex Differ. 2019; 10: 38.
PMCID:
PMC6466809
AbstractArticlePDF–5.6M
8.
Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure
Gabriele G. Schiattarella, Nicola Boccella, Roberta Paolillo, Fabio Cattaneo, Valentina Trimarco, Anna Franzone, Stefania D’Apice, Giuseppe Giugliano, Laura Rinaldi, Domenica Borzacchiello, Alessandra Gentile, Assunta Lombardi, Antonio Feliciello, Giovanni Esposito, Cinzia Perrino
Front Physiol. 2018; 9: 558. Published online 2018 May 28. doi: 10.3389/fphys.2018.00558
PMCID:
PMC5985454
AbstractArticlePDF–4.5M
9.
Siah2 Protein Mediates Early Events in Commitment to an Adipogenic Pathway
Gail Kilroy, David H. Burk, Z. Elizabeth Floyd
J Biol Chem. 2016 Dec 30; 291(53): 27289–27297. Published online 2016 Nov 18. doi: 10.1074/jbc.M116.744672
PMCID:
PMC5207155
AbstractArticlePDF–2.6M
10.
Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition
Shalini Singh, Danielle Howell, Niraj Trivedi, Ketty Kessler, Taren Ong, Pedro Rosmaninho, Alexandre ASF Raposo, Giles Robinson, Martine F Roussel, Diogo S Castro, David J Solecki
eLife. 2016; 5: e12717. Published online 2016 May 14. doi: 10.7554/eLife.12717
PMCID:
PMC4891180
AbstractArticlePDF–11M
11.
Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis
Gabriele Giacomo Schiattarella, Fabio Cattaneo, Gianluigi Pironti, Fabio Magliulo, Giuseppe Carotenuto, Marinella Pirozzi, Roman Polishchuk, Domenica Borzacchiello, Roberta Paolillo, Marco Oliveti, Nicola Boccella, Marisa Avvedimento, Maria Sepe, Assunta Lombardi, Rosa Anna Busiello, Bruno Trimarco, Giovanni Esposito, Antonio Feliciello, Cinzia Perrino
PLoS One. 2016; 11(5): e0154076. Published online 2016 May 2. doi: 10.1371/journal.pone.0154076
Correction in:
PLoS One. 2016; 11(7): e0158934.
PMCID:
PMC4852950
AbstractArticlePDF–5.4M
12.
The Ubiquitin Ligase Siah2 Regulates Obesity-induced Adipose Tissue Inflammation
Gail Kilroy, Lauren E. Carter, Susan Newman, David H. Burk, Justin Manuel, Andreas Möller, David D. Bowtell, Randall L. Mynatt, Sujoy Ghosh, Z. Elizabeth Floyd
Obesity (Silver Spring) Author manuscript; available in PMC 2016 May 18.
Published in final edited form as: Obesity (Silver Spring). 2015 Nov; 23(11): 2223–2232. Published online 2015 Sep 18. doi: 10.1002/oby.21220
PMCID:
PMC4633373
AbstractArticlePDF–2.2M
13.
Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock
Jason P. DeBruyne, Julie E. Baggs, Trey K. Sato, John B. Hogenesch
Proc Natl Acad Sci U S A. 2015 Oct 6; 112(40): 12420–12425. Published online 2015 Sep 21. doi: 10.1073/pnas.1501204112
PMCID:
PMC4603519
AbstractArticlePDF–936K
14.
The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells
Lingling Fan, Guihong Peng, Arif Hussain, Ladan Fazli, Emma Guns, Martin Gleave, Jianfei Qi
J Biol Chem. 2015 Aug 21; 290(34): 20865–20879. Published online 2015 Jul 9. doi: 10.1074/jbc.M115.662155
PMCID:
PMC4543648
AbstractArticlePDF–2.9M
15.
Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation
Jiawen Huang, M. Dafne Cardamone, Holly E. Johnson, Mathieu Neault, Michelle Chan, Z. Elizabeth Floyd, Frédérick A. Mallette, Valentina Perissi
J Biol Chem. 2015 Jul 31; 290(31): 19044–19054. Published online 2015 Jun 12. doi: 10.1074/jbc.M115.637660
PMCID:
PMC4521029
AbstractArticlePDF–928K
16.
Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO
Qiang Li, Ping Wang, Keqiang Ye, Hua Cai
Proc Natl Acad Sci U S A. 2015 Jan 20; 112(3): 899–904. Published online 2015 Jan 5. doi: 10.1073/pnas.1420695112
PMCID:
PMC4311801
AbstractArticlePDF–1.5M
17.
Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2
Marzia Scortegagna, Hyungsoo Kim, Jian-Liang Li, Hang Yao, Laurence M. Brill, Jaeseok Han, Eric Lau, David Bowtell, Gabriel Haddad, Randal J. Kaufman, Ze'ev A. Ronai
PLoS Genet. 2014 May; 10(5): e1004348. Published online 2014 May 8. doi: 10.1371/journal.pgen.1004348
PMCID:
PMC4014425
AbstractArticlePDF–8.6M
18.
Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability
Hyungsoo Kim, Guisepinna Claps, Andreas Möller, David Bowtell, Xin Lu, Ze'ev A. Ronai
Oncogene. Author manuscript; available in PMC 2014 Oct 10.
Published in final edited form as: Oncogene. 2014 Apr 10; 33(15): 2004–2010. Published online 2013 May 6. doi: 10.1038/onc.2013.149
PMCID:
PMC3917971
AbstractArticlePDF–452K
19.
A C-Terminal Acidic Domain Regulates Degradation of the Transcriptional Coactivator Bob1
John M. Lindner, Christina S. F. Wong, Andreas Möller, Peter J. Nielsen
Mol Cell Biol. 2013 Dec; 33(23): 4628–4640. doi: 10.1128/MCB.01590-12
PMCID:
PMC3838006
AbstractArticlePDF–3.2M
20.
The E3 Ubiquitin Ligase Siah2 Contributes to Castration-Resistant Prostate Cancer by Regulation of Androgen Receptor Transcriptional Activity
Jianfei Qi, Manisha Tripathi, Rajeev Mishra, Natasha Sahgal, Ladan Fazil, Susan Ettinger, William J. Placzek, Giuseppina Claps, Leland W.K. Chung, David Bowtell, Martin Gleave, Neil Bhowmick, Ze'ev A. Ronai
Cancer Cell. Author manuscript; available in PMC 2014 Mar 18.
Published in final edited form as: Cancer Cell. 2013 Mar 18; 23(3): 332–346. doi: 10.1016/j.ccr.2013.02.016
Correction in:
volume 23 on page 853
PMCID:
PMC3750989
AbstractArticlePDF–5.3M

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