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Select item 107845241.

Diabetic sensory neuropathy and insulin resistance are induced by loss of UCHL1 in Drosophila

Daewon Lee, Eunju Yoon, Su Jin Ham, Kunwoo Lee, Hansaem Jang, Daihn Woo, Da Hyun Lee, Sehyeon Kim, Sekyu Choi, Jongkyeong Chung

Nat Commun. 2024; 15: 468. Published online 2024 Jan 11. doi: 10.1038/s41467-024-44747-9

PMCID:: PMC10784524

Abstract Article PDF–4.8M

Select item 104448902.

The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy

Yueh-Ling Pai, Yuchieh Jay Lin, Wen-Hsin Peng, Li-Ting Huang, He-Yen Chou, Chien-Hsiang Wang, Cheng-Ting Chien, Guang-Chao Chen

Cell Death Dis. 2023 Aug; 14(8): 540. Published online 2023 Aug 22. doi: 10.1038/s41419-023-06062-x

PMCID:: PMC10444890

Abstract Article PDF–4.9M

Select item 91355333.

Therapeutic Potential of Polyscias fruticosa (L.) Harms Leaf Extract for Parkinson's Disease Treatment by Drosophila melanogaster Model

Hai Trieu Ly, Thi Thu Huong Nguyen, Van Minh Le, Bich Thao Lam, Thi Thu Trinh Mai, Thi Phuong Thao Dang

Oxid Med Cell Longev. 2022; 2022: 5262677. Published online 2022 May 19. doi: 10.1155/2022/5262677

PMCID:: PMC9135533

Abstract Article PDF–2.2M

Select item 89900004.

Usp5, Usp34, and Otu1 deubiquitylases mediate DNA repair in Drosophila melanogaster

Zoltán G. Páhi, Levente Kovács, Diána Szűcs, Barbara N. Borsos, Péter Deák, Tibor Pankotai

Sci Rep. 2022; 12: 5870. Published online 2022 Apr 7. doi: 10.1038/s41598-022-09703-x

PMCID:: PMC8990000

Abstract Article PDF–1.5M

Select item 84688275.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 82704846.

Loss of UCHL1 rescues the defects related to Parkinson’s disease by suppressing glycolysis

Su Jin Ham, Daewon Lee, Wen Jun Xu, Eunjoo Cho, Sekyu Choi, Soohong Min, Sunghyouk Park, Jongkyeong Chung

Sci Adv. 2021 Jul; 7(28): eabg4574. Published online 2021 Jul 9. doi: 10.1126/sciadv.abg4574

PMCID:: PMC8270484

Abstract Article PDF–7.4M

Select item 81297937.

Drosophila USP22/nonstop polarizes the actin cytoskeleton during collective border cell migration

Hammed Badmos, Neville Cobbe, Amy Campbell, Richard Jackson, Daimark Bennett

J Cell Biol. 2021 Jul 5; 220(7): e202007005. Published online 2021 May 14. doi: 10.1083/jcb.202007005

PMCID:: PMC8129793

Abstract Article PDF–6.5M

Select item 81049468.

Highly effective proximate labeling in Drosophila

Bo Zhang, Yuanbing Zhang, Ji-Long Liu

G3 (Bethesda) 2021 May; 11(5): jkab077. Published online 2021 Mar 16. doi: 10.1093/g3journal/jkab077

Correction in:: G3 (Bethesda). 2022 Mar; 12(3): jkac005.

PMCID:: PMC8104946

Abstract Article PDF–1.1M

Select item 76835409.

Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes

Haithem Barbour, Salima Daou, Michael Hendzel, El Bachir Affar

Nat Commun. 2020; 11: 5947. Published online 2020 Nov 23. doi: 10.1038/s41467-020-19722-9

PMCID:: PMC7683540

Abstract Article PDF–1.9M

Select item 750923510.

A new target for an old DUB: UCH-L1 regulates mitofusin-2 levels, altering mitochondrial morphology, function and calcium uptake

Fernanda M. Cerqueira, Sophia von Stockum, Marta Giacomello, Inna Goliand, Pamela Kakimoto, Elena Marchesan, Diego De Stefani, Alicia J. Kowaltowski, Elena Ziviani, Orian S. Shirihai

Redox Biol. 2020 Oct; 37: 101676. Published online 2020 Aug 7. doi: 10.1016/j.redox.2020.101676

PMCID:: PMC7509235

Abstract Article PDF–3.4M

Select item 724646711.

Modeling Neurodegenerative Disorders in Drosophila melanogaster

Harris Bolus, Kassi Crocker, Grace Boekhoff-Falk, Stanislava Chtarbanova

Int J Mol Sci. 2020 May; 21(9): 3055. Published online 2020 Apr 26. doi: 10.3390/ijms21093055

PMCID:: PMC7246467

Abstract Article PDF–2.5M

Select item 712874912.

High-level expression of active recombinant ubiquitin carboxyl-terminal hydrolase of Drosophila melanogaster in Pichia pastoris

Feng-liang Jin, Xiao-xia Xu, Xiao-qiang Yu, Shun-xiang Ren

Protein Expr Purif. 2009 Jun; 65(2): 115–121. Published online 2008 Sep 12. doi: 10.1016/j.pep.2008.08.010

PMCID:: PMC7128749

Abstract Article PDF–751K

Select item 696157813.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 650784414.

Disease model organism for Parkinson disease: Drosophila melanogaster

Binod Aryal, Youngseok Lee

BMB Rep. 2019 Apr; 52(4): 250–258. Published online 2019 Apr 30. doi: 10.5483/BMBRep.2019.52.4.204

PMCID:: PMC6507844

Abstract Article PDF–838K

Select item 650117515.

Evaluating the Potential of Portulaca oleracea L. for Parkinson's Disease Treatment Using a Drosophila Model with dUCH-Knockdown

Huynh Kim Thoa Truong, Man Anh Huynh, My Dung Vuu, Thi Phuong Thao Dang

Parkinsons Dis. 2019; 2019: 1818259. Published online 2019 Apr 18. doi: 10.1155/2019/1818259

PMCID:: PMC6501175

Abstract Article PDF–2.9M

Select item 633432816.

Evaluating Dose- and Time-Dependent Effects of Vitamin C Treatment on a Parkinson's Disease Fly Model

Huynh Man Anh, Dao My Linh, Vuu My Dung, Dang Thi Phuong Thao

Parkinsons Dis. 2019; 2019: 9720546. Published online 2019 Jan 2. doi: 10.1155/2019/9720546

PMCID:: PMC6334328

Abstract Article PDF–6.6M

Select item 607860417.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 605102718.

Curcumin Effectively Rescued Parkinson's Disease-Like Phenotypes in a Novel Drosophila melanogaster Model with dUCH Knockdown

Thi Thanh Nguyen, My Dung Vuu, Man Anh Huynh, Masamitsu Yamaguchi, Linh Thuoc Tran, Thi Phuong Thao Dang

Oxid Med Cell Longev. 2018; 2018: 2038267. Published online 2018 Jul 3. doi: 10.1155/2018/2038267

PMCID:: PMC6051027

Abstract Article PDF–4.7M

Select item 602636619.

A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng)

Qing-Xiu Liu, Wei Zhang, Jia Wang, Wei Hou, Ying-Ping Wang

J Ginseng Res. 2018 Jul; 42(3): 343–351. Published online 2017 Apr 22. doi: 10.1016/j.jgr.2017.04.006

PMCID:: PMC6026366

Abstract Article PDF–1.4M

Select item 587613620.

Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees

Stephanie A. Zlatic, Alysia Vrailas-Mortimer, Avanti Gokhale, Lucas J. Carey, Elizabeth Scott, Reid Burch, Morgan M. McCall, Samantha Rudin-Rush, John Bowen Davis, Cortnie Hartwig, Erica Werner, Lian Li, Michael Petris, Victor Faundez

Cell Syst. Author manuscript; available in PMC 2019 Mar 28.

Published in final edited form as: Cell Syst. 2018 Mar 28; 6(3): 368–380.e6. Published online 2018 Jan 31. doi: 10.1016/j.cels.2018.01.008