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Select item 110887581.

Integrin-linked kinase mRNA expression in circulating mononuclear cells as a biomarker of kidney and vascular damage in experimental chronic kidney disease

Sofía Campillo, Elena Gutiérrez-Calabrés, Susana García-Miranda, Mercedes Griera, Loreto Fernández Rodríguez, Sergio de Frutos, Diego Rodríguez-Puyol, Laura Calleros

Cell Commun Signal. 2024; 22: 264. Published online 2024 May 11. doi: 10.1186/s12964-024-01646-2

PMCID:: PMC11088758

Abstract Article PDF–2.3M

Select item 110721452.

Mechanosensors control skeletal muscle mass, molecular clocks, and metabolism

Mathias Vanmunster, Ana Victoria Rojo Garcia, Alexander Pacolet, Sebastiaan Dalle, Katrien Koppo, Ilse Jonkers, Rik Lories, Frank Suhr

Cell Mol Life Sci. 2022 Jun; 79(6): 321. Published online 2022 May 27. doi: 10.1007/s00018-022-04346-7

PMCID:: PMC11072145

Abstract Article PDF–1.6M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107101624.

Integrin-linked kinase expression in myeloid cells promotes colon tumorigenesis

Afsar U. Ahmed, Saleh Almasabi, Ron Firestein, Bryan R.G. Williams

Front Immunol. 2023; 14: 1270194. Published online 2023 Nov 21. doi: 10.3389/fimmu.2023.1270194

PMCID:: PMC10710162

Abstract Article PDF–6.2M

Select item 94819335.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 89800396.

Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation

Sofía Campillo, Lourdes Bohorquez, Elena Gutiérrez-Calabrés, Diego García-Ayuso, Verónica Miguel, Mercedes Griera, Yolanda Calle, Sergio de Frutos, Manuel Rodríguez-Puyol, Diego Rodríguez-Puyol, Laura Calleros

Exp Mol Med. 2022 Mar; 54(3): 226–238. Published online 2022 Mar 4. doi: 10.1038/s12276-022-00738-8

PMCID:: PMC8980039

Abstract Article PDF–4.0M

Select item 86847267.

Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT

Emann M. Rabie, Sherry X. Zhang, Connor E. Dunn, Celeste M. Nelson

Mol Biol Cell. 2021 Aug 19; 32(18): 1664–1676. doi: 10.1091/mbc.E21-02-0072

PMCID:: PMC8684726

Abstract Article PDF–6.5M

Select item 80988498.

Integrin-linked kinase tunes cell–cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1

Ayse Nihan Kilinc, Siyang Han, Lena A. Barrett, Niroshan Anandasivam, Celeste M. Nelson

Mol Biol Cell. 2021 Mar 1; 32(5): 402–412. doi: 10.1091/mbc.E20-02-0092

PMCID:: PMC8098849

Abstract Article PDF–2.8M

Select item 79491479.

Disruption of the integrin-linked kinase (ILK) pseudokinase domain affects kidney development in mice

Nada Bulus, Kyle L. Brown, Glenda Mernaugh, Anika Böttcher, Xinyu Dong, Charles R. Sanders, Ambra Pozzi, Reinhard Fässler, Roy Zent

J Biol Chem. 2021 Jan-Jun; 296: 100361. Published online 2021 Feb 2. doi: 10.1016/j.jbc.2021.100361

PMCID:: PMC7949147

Article PDF–4.8M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 718595711.

Integrin-linked kinase regulates melanosome trafficking and melanin transfer in melanocytes

Melissa Crawford, Nancy Liu, Elahe Mahdipour, Kevin Barr, Bryan Heit, Lina Dagnino

Mol Biol Cell. 2020 Apr 1; 31(8): 768–781. doi: 10.1091/mbc.E19-09-0510

PMCID:: PMC7185957

Abstract Article PDF–3.7M

Select item 686814012.

Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy

Hongryeol Park, Hiroyuki Yamamoto, Lucas Mohn, Lea Ambühl, Kenichi Kanai, Inga Schmidt, Kee-Pyo Kim, Alessia Fraccaroli, Silke Feil, Harald J. Junge, Eloi Montanez, Wolfgang Berger, Ralf H. Adams

Nat Commun. 2019; 10: 5243. Published online 2019 Nov 20. doi: 10.1038/s41467-019-13220-3

PMCID:: PMC6868140

Abstract Article PDF–10M

Select item 683078513.

Integrin-Linked Kinase Deficiency in Collecting Duct Principal Cell Promotes Necroptosis of Principal Cell and Contributes to Kidney Inflammation and Fibrosis

Ming Huang, Shuai Zhu, Huihui Huang, Jinzhao He, Kenji Tsuji, William W. Jin, Dongping Xie, Onju Ham, Diane E. Capen, Weining Lu, Teodor G. Păunescu, Baoxue Yang, Hua A. Jenny Lu

J Am Soc Nephrol. 2019 Nov; 30(11): 2073–2090. Published online 2019 Oct 25. doi: 10.1681/ASN.2018111162

PMCID:: PMC6830785

Abstract Article

Select item 679784814.

A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice

Chaehyun Yook, Kyungdeok Kim, Doyoun Kim, Hyojin Kang, Sun-Gyun Kim, Eunjoon Kim, Soo Young Kim

Front Mol Neurosci. 2019; 12: 241. Published online 2019 Oct 9. doi: 10.3389/fnmol.2019.00241

PMCID:: PMC6797848

Abstract Article PDF–6.4M

Select item 673265315.

Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner

Elijah Trefts, Curtis C. Hughey, Louise Lantier, Dan S. Lark, Kelli L. Boyd, Ambra Pozzi, Roy Zent, David H. Wasserman

Am J Physiol Endocrinol Metab. 2019 Jun 1; 316(6): E1118–E1135. Published online 2019 Mar 5. doi: 10.1152/ajpendo.00496.2018

PMCID:: PMC6732653

Abstract Article

Select item 661971016.

Integrin-Linked Kinase Regulates Process Extension in Oligodendrocytes via Control of Actin Cytoskeletal Dynamics

Ryan W. O'Meara, John-Paul Michalski, Carrie Anderson, Kunal Bhanot, Peter Rippstein, Rashmi Kothary

J Neurosci. 2013 Jun 5; 33(23): 9781–9793. doi: 10.1523/JNEUROSCI.5582-12.2013

PMCID:: PMC6619710

Abstract Article PDF–2.7M

Select item 660899817.

Dissecting Integrin-Dependent Regulation of Neural Stem Cell Proliferation in the Adult Brain

Cristina Porcheri, Ueli Suter, Sebastian Jessberger

J Neurosci. 2014 Apr 9; 34(15): 5222–5232. doi: 10.1523/JNEUROSCI.4928-13.2014

PMCID:: PMC6608998

Abstract Article PDF–3.5M

Select item 650301918.

Foxc2 is essential for podocyte function

Daniel Nilsson, Mikael Heglind, Zahra Arani, Sven Enerbäck

Physiol Rep. 2019 May; 7(9): e14083. Published online 2019 May 6. doi: 10.14814/phy2.14083

PMCID:: PMC6503019

Abstract Article PDF–15M

Select item 636113619.

Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and β-catenin signaling

Thomas Volckaert, Tingting Yuan, Jie Yuan, Eistine Boateng, Seantel Hopkins, Jin-San Zhang, Victor J. Thannickal, Reinhard Fässler, Stijn P. De Langhe

Development. 2019 Jan 15; 146(2): dev166454. Published online 2019 Jan 16. doi: 10.1242/dev.166454

PMCID:: PMC6361136

Abstract Article

Select item 624418320.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

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