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Items: 1 to 20 of 52

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Muscarinic receptor agonist-induced βPix binding to β-catenin promotes colon neoplasia
Kunrong Cheng, Ahmed Chahdi, Shannon M. Larabee, Mazen Tolaymat, Margaret H. Sundel, Cinthia B. Drachenberg, Min Zhan, Shien Hu, Anan H. Said, Aaron C. Shang, Guofeng Xie, Madeline Alizadeh, Natalia Sampaio Moura, Andrea C. Bafford, Richelle T. Williams, Nader N. Hanna, Jean-Pierre Raufman
Sci Rep. 2023; 13: 16920. Published online 2023 Oct 7. doi: 10.1038/s41598-023-44158-8
PMCID:
PMC10560271
AbstractArticlePDF–2.3M
3.
Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control
Sabrina Schlienger, Patricia T. Yam, Nursen Balekoglu, Hugo Ducuing, Jean-Francois Michaud, Shirin Makihara, Daniel K. Kramer, Baoyu Chen, Alfonso Fasano, Alfredo Berardelli, Fadi F. Hamdan, Guy A. Rouleau, Myriam Srour, Frederic Charron
Sci Adv. 2023 May; 9(19): eadd5501. Published online 2023 May 12. doi: 10.1126/sciadv.add5501
PMCID:
PMC10181192
AbstractArticlePDF–3.1M
4.
Myosin 18Aα targets the guanine nucleotide exchange factor β-Pix to the dendritic spines of cerebellar Purkinje neurons and promotes spine maturation
Christopher J. Alexander, Melanie Barzik, Ikuko Fujiwara, Kirsten Remmert, Ya-Xian Wang, Ronald S. Petralia, Thomas B. Friedman, John A. Hammer
FASEB J. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: FASEB J. 2021 Jan; 35(1): e21092. doi: 10.1096/fj.202001449R
PMCID:
PMC8357457
AbstractArticlePDF–1.6M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
Targeted intestinal deletion of Rho guanine nucleotide exchange factor 7, βPIX, impairs enterocyte proliferation, villus maturation, and mucosal defenses in mice
Kunrong Cheng, Shannon M. Larabee, Mazen Tolaymat, Marie Hanscom, Aaron C. Shang, Alyssa Schledwitz, Shien Hu, Cinthia B. Drachenberg, Min Zhan, Ahmed Chahdi, Jean-Pierre Raufman
Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1; 320(4): G627–G643. Published online 2021 Feb 10. doi: 10.1152/ajpgi.00415.2020
PMCID:
PMC8238171
AbstractArticle
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
β-Pix-dependent cellular protrusions propel collective mesoderm migration in the mouse embryo
Tatiana Omelchenko, Alan Hall, Kathryn V. Anderson
Nat Commun. 2020; 11: 6066. Published online 2020 Nov 27. doi: 10.1038/s41467-020-19889-1
PMCID:
PMC7695707
AbstractArticlePDF–5.1M
9.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
10.
ARHGEF7 (β-PIX) Is Required for the Maintenance of Podocyte Architecture and Glomerular Function
Jun Matsuda, Mirela Maier, Lamine Aoudjit, Cindy Baldwin, Tomoko Takano
J Am Soc Nephrol. 2020 May; 31(5): 996–1008. Published online 2020 Mar 18. doi: 10.1681/ASN.2019090982
PMCID:
PMC7217415
AbstractArticle
11.
βPix-d promotes tubulin acetylation and neurite outgrowth through a PAK/Stathmin1 signaling pathway
Younghee Kwon, Ye Won Jeon, Minjae Kwon, Yongcheol Cho, Dongeun Park, Jung Eun Shin
PLoS One. 2020; 15(4): e0230814. Published online 2020 Apr 6. doi: 10.1371/journal.pone.0230814
Correction in:
PLoS One. 2020; 15(5): e0233327.
PMCID:
PMC7135283
AbstractArticlePDF–3.4M
12.
USP1 deubiquitinates Akt to inhibit PI3K‐Akt‐FoxO signaling in muscle during prolonged starvation
Dana Goldbraikh, Danielle Neufeld, Yara Eid‐Mutlak, Inbal Lasry, Jennifer E Gilda, Anna Parnis, Shenhav Cohen
EMBO Rep. 2020 Apr 3; 21(4): e48791. Published online 2020 Mar 5. doi: 10.15252/embr.201948791
PMCID:
PMC7132338
AbstractArticlePDF–1.6M
13.
A GIT1/PIX/Rac/PAK Signaling Module Regulates Spine Morphogenesis and Synapse Formation through MLC
Huaye Zhang, Donna J. Webb, Hannelore Asmussen, Shuang Niu, Alan F. Horwitz
J Neurosci. 2005 Mar 30; 25(13): 3379–3388. doi: 10.1523/JNEUROSCI.3553-04.2005
PMCID:
PMC6724907
AbstractArticlePDF–1.0M
14.
Loss of βPix Causes Defects in Early Embryonic Development, and Cell Spreading and Platelet-Derived Growth Factor-Induced Chemotaxis in Mouse Embryonic Fibroblasts
TaeIn Kang, Seung Joon Lee, Younghee Kwon, Dongeun Park
Mol Cells. 2019 Aug; 42(8): 589–596. Published online 2019 Aug 9. doi: 10.14348/molcells.2019.0140
PMCID:
PMC6715337
AbstractArticlePDF–3.1M
15.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
16.
Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX
Abira Rajah, Colton G. Boudreau, Alina Ilie, Tse-Luen Wee, Kaixi Tang, Aleksandar Z. Borisov, John Orlowski, Claire M. Brown
Sci Rep. 2019; 9: 11430. Published online 2019 Aug 7. doi: 10.1038/s41598-019-47722-3
PMCID:
PMC6686007
AbstractArticlePDF–11M
17.
The Role of Pak-Interacting Exchange Factor-β Phosphorylation at Serines 340 and 583 by PKCγ in Dopamine Release
Toshihiko Shirafuji, Takehiko Ueyama, Ken-ichi Yoshino, Hideyuki Takahashi, Naoko Adachi, Yukio Ago, Ken Koda, Tetsuaki Nashida, Naoki Hiramatsu, Toshio Matsuda, Tatsushi Toda, Norio Sakai, Naoaki Saito
J Neurosci. 2014 Jul 9; 34(28): 9268–9280. doi: 10.1523/JNEUROSCI.4278-13.2014
PMCID:
PMC6608353
AbstractArticlePDF–2.2M
18.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
19.
β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells
Pei-Yin Ho, Hui Li, Tengis S. Pavlov, Roland D. Tuerk, Diego Tabares, René Brunisholz, Dietbert Neumann, Alexander Staruschenko, Kenneth R. Hallows
J Biol Chem. 2018 Jul 20; 293(29): 11612–11624. Published online 2018 Jun 1. doi: 10.1074/jbc.RA118.003082
PMCID:
PMC6065188
AbstractArticlePDF–1.8M
20.
The guanine nucleotide exchange factor Arhgef7/βPix promotes axon formation upstream of TC10
Alejandro López Tobón, Megalakshmi Suresh, Jing Jin, Alessandro Vitriolo, Thorben Pietralla, Kerry Tedford, Michael Bossenz, Kristina Mahnken, Friedemann Kiefer, Giuseppe Testa, Klaus-Dieter Fischer, Andreas W. Püschel
Sci Rep. 2018; 8: 8811. Published online 2018 Jun 11. doi: 10.1038/s41598-018-27081-1
PMCID:
PMC5995858
AbstractArticlePDF–4.8M

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