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Select item 112138711.

A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain

Sofia Madsen, Ana C. Delgado, Christelle Cadilhac, Vanille Maillard, Fabrice Battiston, Carla Marie Igelbüscher, Simon De Neck, Elia Magrinelli, Denis Jabaudon, Ludovic Telley, Fiona Doetsch, Marlen Knobloch

Nat Commun. 2024; 15: 5489. Published online 2024 Jun 28. doi: 10.1038/s41467-024-49449-w

PMCID:: PMC11213871

Abstract Article PDF–7.1M

Select item 107114822.

Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms

Yifei Li, Dongchang Xiao, Haiqiao Chen, X.F. Steven Zheng, Mengqing Xiang

iScience. 2023 Dec 15; 26(12): 108544. Published online 2023 Nov 23. doi: 10.1016/j.isci.2023.108544

PMCID:: PMC10711482

Abstract Article PDF–9.9M

Select item 105896733.

Impairment of serine transport across the blood–brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction

Inna Radzishevsky, Maali Odeh, Oded Bodner, Salman Zubedat, Lihi Shaulov, Maxim Litvak, Kayoko Esaki, Takeo Yoshikawa, Bella Agranovich, Wen-Hong Li, Alex Radzishevsky, Eyal Gottlieb, Avi Avital, Herman Wolosker

Proc Natl Acad Sci U S A. 2023 Oct 17; 120(42): e2302780120. Published online 2023 Oct 9. doi: 10.1073/pnas.2302780120

PMCID:: PMC10589673

Abstract Article PDF–6.8M

Select item 103659854.

Image-based quantification of histological features as a function of spatial location using the Tissue Positioning System

Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang, Hao Zhu, Guanghua Xiao, Yunguan Wang

eBioMedicine. 2023 Aug; 94: 104698. Published online 2023 Jul 13. doi: 10.1016/j.ebiom.2023.104698

PMCID:: PMC10365985

Abstract Article PDF–5.4M

Select item 102127165.

Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain

Yuanyuan Wang, Libo Su, Wenwen Wang, Jinyue Zhao, Yanyan Wang, Sihan Li, Yan Liu, Renjie Chai, Xin Li, Zhaoqian Teng, Changmei Liu, Baoyang Hu, Fen Ji, Jianwei Jiao

Cell Prolif. 2023 May; 56(5): e13447. Published online 2023 Mar 13. doi: 10.1111/cpr.13447

PMCID:: PMC10212716

Abstract Article PDF–4.7M

Select item 98887256.

Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent

Sarah A. Comerford, Elizabeth A. Hinnant, Yidong Chen, Robert E. Hammer

PLoS Genet. 2023 Jan; 19(1): e1010595. Published online 2023 Jan 19. doi: 10.1371/journal.pgen.1010595

PMCID:: PMC9888725

Abstract Article PDF–6.9M

Select item 97540027.

Glutamine synthetase limits β-catenin–mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1

Weiwei Dai, Jianliang Shen, Junrong Yan, Alex J. Bott, Sara Maimouni, Heineken Q. Daguplo, Yujue Wang, Khoosheh Khayati, Jessie Yanxiang Guo, Lanjing Zhang, Yongbo Wang, Alexander Valvezan, Wen-Xing Ding, Xin Chen, Xiaoyang Su, Shenglan Gao, Wei-Xing Zong

J Clin Invest. 2022 Dec 15; 132(24): e161408. Published online 2022 Dec 15. doi: 10.1172/JCI161408

PMCID:: PMC9754002

Abstract Article PDF–34M

Select item 96038608.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 94244899.

Volumetric imaging reveals VEGF-C-dependent formation of hepatic lymph vessels in mice

Stefanie Bobe, Daniel Beckmann, Dorothee Maria Klump, Cathrin Dierkes, Nils Kirschnick, Esther Redder, Nadine Bauer, Michael Schäfers, Raghu Erapaneedi, Benjamin Risse, Serge A. van de Pavert, Friedemann Kiefer

Front Cell Dev Biol. 2022; 10: 949896. Published online 2022 Aug 16. doi: 10.3389/fcell.2022.949896

PMCID:: PMC9424489

Abstract Article PDF–6.0M

Select item 937601410.

Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex

Xiaoping Wu, Alexander A. Sosunov, Wudu Lado, Jia Jie Teoh, Ahrom Ham, Hongyu Li, Osama Al-Dalahmah, Brian J.A. Gill, Ottavio Arancio, Catherine A. Schevon, Wayne N. Frankel, Guy M. McKhann, II, David Sulzer, James E. Goldman, Guomei Tang

Cell Rep. Author manuscript; available in PMC 2022 Aug 14.

Published in final edited form as: Cell Rep. 2022 Jul 19; 40(3): 111085. doi: 10.1016/j.celrep.2022.111085

PMCID:: PMC9376014

Abstract Article PDF–4.2M

Select item 909083211.

Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression

Norihisa Bizen, Asim K. Bepari, Li Zhou, Manabu Abe, Kenji Sakimura, Katsuhiko Ono, Hirohide Takebayashi

Cell Death Differ. 2022 May; 29(5): 1028–1041. Published online 2022 Jan 1. doi: 10.1038/s41418-021-00915-8

PMCID:: PMC9090832

Abstract Article PDF–8.5M

Select item 857784912.

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

Soyeon Lim, You-Joung Kim, Sooyeon Park, Ji-heon Choi, Young Hoon Sung, Katsuhiko Nishimori, Zbynek Kozmik, Han-Woong Lee, Jin Woo Kim

eLife. 2021; 10: e70079. Published online 2021 Oct 22. doi: 10.7554/eLife.70079

PMCID:: PMC8577849

Abstract Article PDF–10M

Select item 850220513.

Evidence for glutamine synthetase function in mouse spinal cord oligodendrocytes

Lucile Ben Haim, Lucas Schirmer, Amel Zulji, Khalida Sabeur, Brice Tiret, Matthieu Ribon, Sandra Chang, Wouter H. Lamers, Séverine BoillEée, Myriam M. Chaumeil, David H. Rowitch

Glia. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Glia. 2021 Dec; 69(12): 2812–2827. Published online 2021 Aug 15. doi: 10.1002/glia.24071

PMCID:: PMC8502205

Abstract Article PDF–3.5M

Select item 849642014.

Liver homeostasis is maintained by midlobular zone 2 hepatocytes

Yonglong Wei, Yunguan G. Wang, Yuemeng Jia, Lin Li, Jung Yoon, Shuyuan Zhang, Zixi Wang, Yu Zhang, Min Zhu, Tripti Sharma, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Jeffrey H. Albrecht, Phuong T. Le, Clifford J. Rosen, Tao Wang, Hao Zhu

Science. Author manuscript; available in PMC 2021 Oct 7.

Published in final edited form as: Science. 2021 Feb 26; 371(6532): eabb1625. doi: 10.1126/science.abb1625

PMCID:: PMC8496420

Abstract Article PDF–6.4M

Select item 849608415.

S100B is selectively expressed by gray matter protoplasmic astrocytes and myelinating oligodendrocytes in the developing CNS

Junqing Du, Min Yi, Fang Zhou, Wanjun He, Aifen Yang, Mengsheng Qiu, Hao Huang

Mol Brain. 2021; 14: 154. Published online 2021 Oct 6. doi: 10.1186/s13041-021-00865-9

PMCID:: PMC8496084

Abstract Article PDF–9.0M

Select item 826190416.

Selective deletion of glutamine synthetase in the mouse cerebral cortex induces glial dysfunction and vascular impairment that precede epilepsy and neurodegeneration

Yun Zhou, Roni Dhaher, Maxime Parent, Qiu-Xiang Hu, Bjørnar Hassel, Yee Siu-Pok, Fahmeed Hyder, Shaun E Gruenbaum, Tore Eid, Niels Christian Danbolt

Neurochem Int. Author manuscript; available in PMC 2021 Jul 7.

Published in final edited form as: Neurochem Int. 2019 Feb; 123: 22–33. Published online 2018 Jul 24. doi: 10.1016/j.neuint.2018.07.009

PMCID:: PMC8261904

Abstract Article PDF–1.3M

Select item 818539517.

Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype

Mengjuan Wu, Qinqin Deng, Xinlan Lei, Yuxin Du, Yin Shen

Invest Ophthalmol Vis Sci. 2021 Jun; 62(7): 1. Published online 2021 Jun 1. doi: 10.1167/iovs.62.7.1

PMCID:: PMC8185395

Abstract Article PDF–15M

Select item 783841818.

Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract

Rupalatha Maddala, Junyuan Gao, Richard T. Mathias, Tylor R. Lewis, Vadim Y. Arshavsky, Adriana Levine, Jonathan M. Backer, Anne R. Bresnick, Ponugoti V. Rao

Sci Rep. 2021; 11: 2203. Published online 2021 Jan 26. doi: 10.1038/s41598-021-81611-y