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Items: 1 to 20 of 65

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Presenilin and APP Regulate Synaptic Kainate Receptors
Gaël Barthet, Ana Moreira-de-Sá, Pei Zhang, Séverine Deforges, Jorge Castanheira, Adam Gorlewicz, Christophe Mulle
J Neurosci. 2022 Dec 7; 42(49): 9253–9262. doi: 10.1523/JNEUROSCI.0297-22.2022
PMCID:
PMC9761675
AbstractArticlePDF–2.0M
3.
Regulation of gene expression by the APP family in the adult cerebral cortex
Hye Ji Cha, Jie Shen, Jongkyun Kang
Sci Rep. 2022; 12: 66. Published online 2022 Jan 7. doi: 10.1038/s41598-021-04027-8
PMCID:
PMC8741778
AbstractArticlePDF–2.8M
4.
Sex-dependent effects of amyloid precursor-like protein 2 in the SOD1-G37R transgenic mouse model of MND
Phan H. Truong, Peter J. Crouch, James B. W. Hilton, Catriona A. McLean, Roberto Cappai, Giuseppe D. Ciccotosto
Cell Mol Life Sci. 2021 Oct; 78(19-20): 6605–6630. Published online 2021 Sep 2. doi: 10.1007/s00018-021-03924-5
PMCID:
PMC8558206
AbstractArticlePDF–10M
5.
APPsα rescues impaired Ca2+ homeostasis in APP- and APLP2-deficient hippocampal neurons
Susann Ludewig, Ulrike Herrmann, Kristin Michaelsen-Preusse, Kristin Metzdorf, Jennifer Just, Charlotte Bold, Ulrike C. Müller, Martin Korte
Proc Natl Acad Sci U S A. 2021 Jun 29; 118(26): e2011506118. Published online 2021 Jun 25. doi: 10.1073/pnas.2011506118
PMCID:
PMC8256088
AbstractArticlePDF–2.0M
6.
Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism‐like phenotype
Vicky Steubler, Susanne Erdinger, Michaela K Back, Susann Ludewig, Dominique Fässler, Max Richter, Kang Han, Lutz Slomianka, Irmgard Amrein, Jakob von Engelhardt, David P Wolfer, Martin Korte, Ulrike C Müller
EMBO J. 2021 Jun 15; 40(12): e107471. Published online 2021 May 19. doi: 10.15252/embj.2020107471
PMCID:
PMC8204861
AbstractArticlePDF–3.7M
7.
Amyloid Precursor-like Protein 2 Expression Increases during Pancreatic Cancer Development and Shortens the Survival of a Spontaneous Mouse Model of Pancreatic Cancer
Brittany J. Poelaert, Shelby M. Knoche, Alaina C. Larson, Poomy Pandey, Parthasarathy Seshacharyulu, Nuzhat Khan, H. Carlo Maurer, Kenneth P. Olive, Yuri Sheinin, Rizwan Ahmad, Amar B. Singh, Surinder K. Batra, Satyanarayana Rachagani, Joyce C. Solheim
Cancers (Basel) 2021 Apr; 13(7): 1535. Published online 2021 Mar 26. doi: 10.3390/cancers13071535
PMCID:
PMC8036577
AbstractArticlePDF–3.1M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival
Sang Hun Lee, Jongkyun Kang, Angela Ho, Hirotaka Watanabe, Vadim Y. Bolshakov, Jie Shen
Neuron. Author manuscript; available in PMC 2021 Nov 25.
Published in final edited form as: Neuron. 2020 Nov 25; 108(4): 676–690.e8. Published online 2020 Sep 4. doi: 10.1016/j.neuron.2020.08.011
PMCID:
PMC7704911
AbstractArticlePDF–2.9M
10.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
11.
Disabled-1 Binds to the Cytoplasmic Domain of Amyloid Precursor-Like Protein 1
Ramin Homayouni, Dennis S. Rice, Michael Sheldon, Tom Curran
J Neurosci. 1999 Sep 1; 19(17): 7507–7515. doi: 10.1523/JNEUROSCI.19-17-07507.1999
PMCID:
PMC6782519
AbstractArticlePDF–633K
12.
Mice with Combined Gene Knock-Outs Reveal Essential and Partially Redundant Functions of Amyloid Precursor Protein Family Members
Sabine Heber, Jochen Herms, Vladan Gajic, Johannes Hainfellner, Adriano Aguzzi, Thomas Rülicke, Hans Kretzschmar, Cornelia von Koch, Sangram Sisodia, Phillippe Tremml, Hans-Peter Lipp, David P. Wolfer, Ulrike Müller
J Neurosci. 2000 Nov 1; 20(21): 7951–7963. doi: 10.1523/JNEUROSCI.20-21-07951.2000
Correction in:
J Neurosci. 2020 Sep 16; 40(38): 7375.
PMCID:
PMC6772747
AbstractArticlePDF–814K
13.
Caspases 3 and 9 Send a Pro-Apoptotic Signal from Synapse to Cell Body in Olfactory Receptor Neurons
Catherine M. Cowan, Jimmy Thai, Stanislaw Krajewski, John C. Reed, Donald W. Nicholson, Scott H. Kaufmann, A. Jane Roskams
J Neurosci. 2001 Sep 15; 21(18): 7099–7109. doi: 10.1523/JNEUROSCI.21-18-07099.2001
PMCID:
PMC6763014
AbstractArticlePDF–1.5M
14.
Nuclear Translocation of the p75 Neurotrophin Receptor Cytoplasmic Domain in Response to Neurotrophin Binding
José M. Frade
J Neurosci. 2005 Feb 9; 25(6): 1407–1411. doi: 10.1523/JNEUROSCI.3798-04.2005
PMCID:
PMC6726010
AbstractArticlePDF–232K
15.
Defective Neuromuscular Synapses in Mice Lacking Amyloid Precursor Protein (APP) and APP-Like Protein 2
Pei Wang, Guang Yang, Dennis R. Mosier, Paul Chang, Tahire Zaidi, Yan-Dao Gong, Nan-Ming Zhao, Bertha Dominguez, Kuo-Fen Lee, Wen-Biao Gan, Hui Zheng
J Neurosci. 2005 Feb 2; 25(5): 1219–1225. doi: 10.1523/JNEUROSCI.4660-04.2005
PMCID:
PMC6725967
AbstractArticlePDF–509K
16.
Loss of γ-Secretase Function Impairs Endocytosis of Lipoprotein Particles and Membrane Cholesterol Homeostasis
Irfan Y. Tamboli, Kai Prager, Dietmar R. Thal, Karin M. Thelen, Ilse Dewachter, Claus U. Pietrzik, Peter St. George-Hyslop, Sangram S. Sisodia, Bart De Strooper, Michael T. Heneka, Mikhail A. Filippov, Ulrike Müller, Fred van Leuven, Dieter Lütjohann, Jochen Walter
J Neurosci. 2008 Nov 12; 28(46): 12097–12106. doi: 10.1523/JNEUROSCI.2635-08.2008
PMCID:
PMC6671640
AbstractArticlePDF–591K
17.
The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior
Maja Klevanski, Ulrike Herrmann, Sascha W. Weyer, Romain Fol, Nathalie Cartier, David P. Wolfer, John H. Caldwell, Martin Korte, Ulrike C. Müller
J Neurosci. 2015 Dec 9; 35(49): 16018–16033. doi: 10.1523/JNEUROSCI.2009-15.2015
PMCID:
PMC6605503
AbstractArticlePDF–3.7M
18.
APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission
Sandra Schilling, Annika Mehr, Susann Ludewig, Jonathan Stephan, Marius Zimmermann, Alexander August, Paul Strecker, Martin Korte, Edward H. Koo, Ulrike C. Müller, Stefan Kins, Simone Eggert
J Neurosci. 2017 May 24; 37(21): 5345–5365. doi: 10.1523/JNEUROSCI.1875-16.2017
PMCID:
PMC6596463
AbstractArticlePDF–5.9M
19.
Distribution of an APP homolog, APLP2, in the mouse olfactory system: a potential role for APLP2 in axogenesis
G Thinakaran, CA Kitt, AJ Roskams, HH Slunt, E Masliah, C von Koch, SD Ginsberg, GV Ronnett, RR Reed, DL Price
J Neurosci. 1995 Oct 1; 15(10): 6314–6326. doi: 10.1523/JNEUROSCI.15-10-06314.1995
PMCID:
PMC6577992
AbstractPDF–7.5M
20.
Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition
Max C Richter, Susann Ludewig, Alex Winschel, Tobias Abel, Charlotte Bold, Leonie R Salzburger, Susanne Klein, Kang Han, Sascha W Weyer, Ann‐Kristina Fritz, Bodo Laube, David P Wolfer, Christian J Buchholz, Martin Korte, Ulrike C Müller
EMBO J. 2018 Jun 1; 37(11): e98335. Published online 2018 Apr 16. doi: 10.15252/embj.201798335
PMCID:
PMC5983155
AbstractArticlePDF–1.4M

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