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Select item 110993821.

Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2

Sheridan H. Littleton, Khanh B. Trang, Christina M. Volpe, Kieona Cook, Nicole DeBruyne, Jean Ann Maguire, Mary Ann Weidekamp, Kenyaita M. Hodge, Keith Boehm, Sumei Lu, Alessandra Chesi, Jonathan P. Bradfield, James A. Pippin, Stewart A. Anderson, Andrew D. Wells, Matthew C. Pahl, Struan F.A. Grant

Cell Genom. 2024 May 8; 4(5): 100556. Published online 2024 May 1. doi: 10.1016/j.xgen.2024.100556

PMCID:: PMC11099382

Abstract Article PDF–6.6M

Select item 101183302.

Xiaojun Zhou, Hao Zhao

Medicine (Baltimore) 2023 Apr 21; 102(16): e33591. Published online 2023 Apr 21. doi: 10.1097/MD.0000000000033591

PMCID:: PMC10118330

Abstract Article PDF–1.8M

Select item 90387303.

Antiapoptotic Protein FAIM2 is targeted by miR-3202, and DUX4 via TRIM21, leading to cell death and defective myogenesis

Hossam A. N. Soliman, Erik A. Toso, Inas E. Darwish, Samia M. Ali, Michael Kyba

Cell Death Dis. 2022 Apr; 13(4): 405. Published online 2022 Apr 25. doi: 10.1038/s41419-022-04804-x

PMCID:: PMC9038730

Abstract Article PDF–5.2M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76450325.

Analysis of Polymorphisms rs7093069-IL-2RA, rs7138803-FAIM2, and rs1748033-PADI4 in the Group of Adolescents With Autoimmune Thyroid Diseases

Beata Sawicka, Hanna Borysewicz-Sańczyk, Natalia Wawrusiewicz-Kurylonek, Tommaso Aversa, Domenico Corica, Joanna Gościk, Adam Krętowski, Małgorzata Waśniewska, Artur Bossowski

Front Endocrinol (Lausanne) 2020; 11: 544658. Published online 2020 Oct 23. doi: 10.3389/fendo.2020.544658

PMCID:: PMC7645032

Abstract Article PDF–296K

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 71065787.

Jing Kang, Ren-Chu Guan, Ying Zhao, Yan Chen

BMC Med Genet. 2020; 21: 65. Published online 2020 Mar 30. doi: 10.1186/s12881-020-00999-y

PMCID:: PMC7106578

Abstract Article PDF–520K

Select item 65289318.

miR‐193b availability is antagonized by LncRNA‐SNHG7 for FAIM2‐induced tumour progression in non‐small cell lung cancer

Kelin She, Hui Yan, Jun Huang, Huaping Zhou, Jianxing He

Cell Prolif. 2018 Feb; 51(1): e12406. Published online 2017 Nov 12. doi: 10.1111/cpr.12406

PMCID:: PMC6528931

Abstract Article PDF–1.1M

Select item 62759209.

The anti-apoptotic protein lifeguard is expressed in breast cancer cells and tissues

Vesna Bucan, Kerstin Reimers, Claudia Yu Choi, Mau-Thek Eddy, Peter M. Vogt

Cell Mol Biol Lett. 2010 Jun; 15(2): 296–310. Published online 2010 Mar 19. doi: 10.2478/s11658-010-0009-1

PMCID:: PMC6275920

Summary PDF–20M

Select item 471421010.

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells

Jorge Urresti, Marisol Ruiz-Meana, Elena Coccia, Juan Carlos Arévalo, José Castellano, Celia Fernández-Sanz, Koen M. O. Galenkamp, Laura Planells-Ferrer, Rana S. Moubarak, Núria Llecha-Cano, Stéphanie Reix, David García-Dorado, Bruna Barneda-Zahonero, Joan X. Comella

J Biol Chem. 2016 Jan 15; 291(3): 1221–1234. Published online 2015 Nov 18. doi: 10.1074/jbc.M115.677682

PMCID:: PMC4714210

Abstract Article PDF–2.9M

Select item 464794111.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 459918312.

TRIM21, a negative modulator of LFG in breast carcinoma MDA-MB-231 cells in vitro

JUDITH MÜLLER, VIKTOR MAURER, KERSTIN REIMERS, PETER M. VOGT, VESNA BUCAN

Int J Oncol. 2015 Nov; 47(5): 1634–1646. Published online 2015 Sep 16. doi: 10.3892/ijo.2015.3169

PMCID:: PMC4599183

Abstract Article PDF–845K

Select item 442096113.

Influence of lifestyle on the FAIM2 promoter methylation between obese and lean children: a cohort study

Lijun Wu, Xiaoyuan Zhao, Yue Shen, Guimin Huang, Meixian Zhang, Yinkun Yan, Dongqing Hou, Linghui Meng, Junting Liu, Hong Cheng, Jie Mi

BMJ Open. 2015; 5(4): e007670. Published online 2015 Apr 28. doi: 10.1136/bmjopen-2015-007670

PMCID:: PMC4420961

Abstract Article PDF–624K

Select item 421875114.

Genome-wide Association Study of Obsessive-Compulsive Disorder

S Evelyn Stewart, Dongmei Yu, Jeremiah M Scharf, Benjamin M Neale, Jesen A Fagerness, Carol A Mathews, Paul D Arnold, Patrick D Evans, Eric R Gamazon, Lisa Osiecki, Lauren McGrath, Stephen Haddad, Jacquelyn Crane, Dianne Hezel, Cornelia Illman, Catherine Mayerfeld, Anuar Konkashbaev, Chunyu Liu, Anna Pluzhnikov, Anna Tikhomirov, Christopher K Edlund, Scott L Rauch, Rainald Moessner, Peter Falkai, Wolfgang Maier, Stephan Ruhrmann, Hans-Jörgen Grabe, Leonard Lennertz, Michael Wagner, Laura Bellodi, Maria Cristina Cavallini, Margaret A Richter, Edwin H Cook, Jr, James L Kennedy, David Rosenberg, Dan J Stein, Sian MJ Hemmings, Christine Lochner, Amin Azzam, Denise A Chavira, Eduardo Fournier, Helena Garrido, Brooke Sheppard, Paul Umaña, Dennis L Murphy, Jens R Wendland, Jeremy Veenstra-VanderWeele, Damiaan Denys, Rianne Blom, Dieter Deforce, Filip Van Nieuwerburgh, Herman GM Westenberg, Susanne Walitza, Karin Egberts, Tobias Renner, Euripedes Constantino Miguel, Carolina Cappi, Ana G Hounie, Maria Conceição do Rosário, Aline S Sampaio, Homero Vallada, Humberto Nicolini, Nuria Lanzagorta, Beatriz Camarena, Richard Delorme, Marion Leboyer, Carlos N Pato, Michele T Pato, Emanuel Voyiaziakis, Peter Heutink, Danielle C Cath, Danielle Posthuma, Jan H Smit, Jack Samuels, O Joseph Bienvenu, Bernadette Cullen, Abby J Fyer, Marco A Grados, Benjamin D Greenberg, James T McCracken, Mark A Riddle, Ying Wang, Vladimir Coric, James F Leckman, Michael Bloch, Christopher Pittenger, Valsamma Eapen, Donald W Black, Roel A Ophoff, Eric Strengman, Daniele Cusi, Maurizio Turiel, Francesca Frau, Fabio Macciardi, J Raphael Gibbs, Mark R Cookson, Andrew Singleton, for North American Brain Expression Consortium, John Hardy, for the UK Brain Expression Database, Andrew T Crenshaw, Melissa A Parkin, Daniel B Mirel, David V Conti, Shaun Purcell, Gerald Nestadt, Gregory L Hanna, Michael A Jenike, James A Knowles, Nancy Cox, David L Pauls

Mol Psychiatry. Author manuscript; available in PMC 2014 Nov 3.

Published in final edited form as: Mol Psychiatry. 2013 Jul; 18(7): 788–798. Published online 2012 Aug 14. doi: 10.1038/mp.2012.85

Correction in:: volume 18 on page 843

PMCID:: PMC4218751

Abstract Article PDF–1.8M

Select item 414836515.

Role of Lifeguard β-isoform in the development of breast cancer

NADJIB DASTAGIR, ANDREA LAZARIDIS, KHALED DASTAGIR, KERSTIN REIMERS, PETER M. VOGT, VESNA BUCAN

Oncol Rep. 2014 Oct; 32(4): 1335–1340. Published online 2014 Jul 25. doi: 10.3892/or.2014.3363

PMCID:: PMC4148365

Abstract Article PDF–706K

Select item 400825516.

Meta-analyses between 18 candidate genetic markers and overweight/obesity

Linlin Tang, Huadan Ye, Qingxiao Hong, Fei Chen, Qinwen Wang, Leiting Xu, Shizhong Bu, Qiong Liu, Meng Ye, Dao Wen Wang, Yifeng Mai, Shiwei Duan

Diagn Pathol. 2014; 9: 56. Published online 2014 Mar 12. doi: 10.1186/1746-1596-9-56

PMCID:: PMC4008255

Abstract Article PDF–1.6M

Select item 397883017.

Modulation of Hippocampal Neuroplasticity by Fas/CD95 Regulatory Protein 2 (Faim2) in the Course of Bacterial Meningitis

Simone C. Tauber, Kristian Harms, Björn Falkenburger, Joachim Weis, Bernd Sellhaus, Roland Nau, Jörg B. Schulz, Arno Reich

J Neuropathol Exp Neurol. 2014 Jan; 73(1): 2–13. Published online 2013 Dec 19. doi: 10.1097/NEN.0000000000000020

PMCID:: PMC3978830

Abstract Article PDF–43M

Select item 392296618.

Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial

Dolores Corella, Jose V Sorlí, José I González, Carolina Ortega, Montserrat Fitó, Monica Bulló, Miguel Angel Martínez-González, Emilio Ros, Fernando Arós, José Lapetra, Enrique Gómez-Gracia, Lluís Serra-Majem, Valentina Ruiz-Gutierrez, Miquel Fiol, Oscar Coltell, Ernest Vinyoles, Xavier Pintó, Amelia Martí, Carmen Saiz, José M Ordovás, Ramón Estruch

Cardiovasc Diabetol. 2014; 13: 5. Published online 2014 Jan 6. doi: 10.1186/1475-2840-13-5

PMCID:: PMC3922966

Abstract Article PDF–448K

Select item 376513419.

Common rs7138803 variant of FAIM2 and obesity in Han Chinese

Cong Li, Xueping Qiu, Na Yang, Jiajia Gao, Yuan Rong, Chenling Xiong, Fang Zheng

BMC Cardiovasc Disord. 2013; 13: 56. Published online 2013 Aug 8. doi: 10.1186/1471-2261-13-56

PMCID:: PMC3765134

Abstract Article PDF–304K

Select item 319320920.

Antiapoptotic protein Lifeguard is required for survival and maintenance of Purkinje and granular cells

Tatiana Hurtado de Mendoza, Carlos G. Perez-Garcia, Todd T. Kroll, Nien H. Hoong, Dennis D. M. O'Leary, Inder M. Verma

Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41): 17189–17194. Published online 2011 Sep 28. doi: 10.1073/pnas.1114226108

Correction in:: Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32): 11906.

PMCID:: PMC3193209

Abstract Article PDF–1.5M

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