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Select item 110990661.

Differential SNARE chaperoning by Munc13-1 and Munc18-1 dictates fusion pore fate at the release site

Bhavya R. Bhaskar, Laxmi Yadav, Malavika Sriram, Kinjal Sanghrajka, Mayank Gupta, Boby K. V, Rohith K. Nellikka, Debasis Das

Nat Commun. 2024; 15: 4132. Published online 2024 May 16. doi: 10.1038/s41467-024-46965-7

PMCID:: PMC11099066

Abstract Article PDF–7.7M

Select item 96382832.

Munc18-1 Contributes to Hippocampal Injury in Septic Rats Through Regulation of Syntanxin1A and Synaptophysin and Glutamate Levels

Fajuan Tang, Lin Chen, Hu Gao, Yupeng Lei, Linli Pan, Dongqiong Xiao, Xihong Li

Neurochem Res. 2023; 48(3): 791–803. Published online 2022 Nov 5. doi: 10.1007/s11064-022-03806-7

PMCID:: PMC9638283

Abstract Article PDF–5.5M

Select item 78944553.

STXBP1 forms amyloid-like aggregates in rat brain and demonstrates amyloid properties in bacterial expression system

A.V. Chirinskaite, V.A. Siniukova, M.E. Velizhanina, J.V. Sopova, T.A. Belashova, S.P. Zadorsky

Prion. 2021; 15(1): 29–36. Published online 2021 Feb 16. doi: 10.1080/19336896.2021.1883980

PMCID:: PMC7894455

Abstract Article PDF–3.6M

Select item 78487014.

Synaptotagmin-1–, Munc18-1–, and Munc13-1–dependent liposome fusion with a few neuronal SNAREs

Karolina P. Stepien, Josep Rizo

Proc Natl Acad Sci U S A. 2021 Jan 26; 118(4): e2019314118. Published online 2021 Jan 18. doi: 10.1073/pnas.2019314118

PMCID:: PMC7848701

Abstract Article PDF–1.8M

Select item 74297365.

Munc13 activates the Munc18‐1/syntaxin‐1 complex and enables Munc18‐1 to prime SNARE assembly

Xianping Wang, Jihong Gong, Le Zhu, Shen Wang, Xiaoyu Yang, Yuanyuan Xu, Xiaofei Yang, Cong Ma

EMBO J. 2020 Aug 17; 39(16): e103631. Published online 2020 Jul 9. doi: 10.15252/embj.2019103631

PMCID:: PMC7429736

Abstract Article PDF–3.8M

Select item 73638316.

Munc18-1 induces conformational changes of syntaxin-1 in multiple intermediates for SNARE assembly

Sanghwa Lee, Jonghyeok Shin, Younghun Jung, Heyjin Son, Jaeil Shin, Cherlhyun Jeong, Dae-Hyuk Kweon, Yeon-Kyun Shin

Sci Rep. 2020; 10: 11623. Published online 2020 Jul 15. doi: 10.1038/s41598-020-68476-3

PMCID:: PMC7363831

Abstract Article PDF–1.4M

Select item 66749677.

Genetic Analysis of Mint/X11 Proteins: Essential Presynaptic Functions of a Neuronal Adaptor Protein Family

Angela Ho, Wade Morishita, Deniz Atasoy, Xinran Liu, Katsuhiko Tabuchi, Robert E. Hammer, Robert C. Malenka, Thomas C. Südhof

J Neurosci. 2006 Dec 13; 26(50): 13089–13101. doi: 10.1523/JNEUROSCI.2855-06.2006

PMCID:: PMC6674967

Abstract Article PDF–1.0M

Select item 63252398.

Munc18 and Munc13 serve as a functional template to orchestrate neuronal SNARE complex assembly

Shen Wang, Yun Li, Jihong Gong, Sheng Ye, Xiaofei Yang, Rongguang Zhang, Cong Ma

Nat Commun. 2019; 10: 69. Published online 2019 Jan 8. doi: 10.1038/s41467-018-08028-6

PMCID:: PMC6325239

Abstract Article PDF–3.7M

Select item 60398709.

LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells

Philipp Trepte, Sabrina Kruse, Simona Kostova, Sheila Hoffmann, Alexander Buntru, Anne Tempelmeier, Christopher Secker, Lisa Diez, Aline Schulz, Konrad Klockmeier, Martina Zenkner, Sabrina Golusik, Kirstin Rau, Sigrid Schnoegl, Craig C Garner, Erich E Wanker

Mol Syst Biol. 2018 Jul; 14(7): e8071. Published online 2018 Jul 11. doi: 10.15252/msb.20178071

PMCID:: PMC6039870

Abstract Article PDF–2.1M

Select item 582495810.

Identification and characterization of the BRI2 interactome in the brain

Filipa Martins, Ana M. Marafona, Cátia D. Pereira, Thorsten Müller, Christina Loosse, Katharina Kolbe, Odete A. B. da Cruz e Silva, Sandra Rebelo

Sci Rep. 2018; 8: 3548. Published online 2018 Feb 23. doi: 10.1038/s41598-018-21453-3

PMCID:: PMC5824958

Abstract Article PDF–1.7M

Select item 565168311.

Munc18a Clusters SNARE-Bearing Liposomes Prior to Trans-SNARE Zippering

Matthew Grant Arnold, Pratikshya Adhikari, Baobin Kang, Hao Xu (徐昊)

Biochem J. Author manuscript; available in PMC 2018 Sep 24.

Published in final edited form as: Biochem J. 2017 Sep 24; 474(19): 3339–3354. Published online 2017 Sep 24. doi: 10.1042/BCJ20170494

PMCID:: PMC5651683

Abstract Article PDF–915K

Select item 556036012.

Effect of neuronal excitotoxicity on Munc18-1 distribution in nuclei of rat hippocampal neuron and primary cultured neuron

Yan-Ping Zhang, Ping Wan, Hong-Quan Wang, Hong Zhao, Yu-Xia Xu, Ru Yang, Cui-Qing Zhu

Neurosci Bull. 2011 Jun; 27(3): 163. Published online 2011 Jun 4. doi: 10.1007/s12264-011-1007-7

PMCID:: PMC5560360

Abstract Article PDF–1.5M

Select item 547004013.

An activated Q‐SNARE/SM protein complex as a possible intermediate in SNARE assembly

Shrutee Jakhanwal, Chung‐Tien Lee, Henning Urlaub, Reinhard Jahn

EMBO J. 2017 Jun 14; 36(12): 1788–1802. Published online 2017 May 8. doi: 10.15252/embj.201696270

PMCID:: PMC5470040

Abstract Article PDF–2.3M

Select item 546477214.

Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion

Ewa Sitarska, Junjie Xu, Seungmee Park, Xiaoxia Liu, Bradley Quade, Karolina Stepien, Kyoko Sugita, Chad A Brautigam, Shuzo Sugita, Josep Rizo

eLife. 2017; 6: e24278. Published online 2017 May 6. doi: 10.7554/eLife.24278

PMCID:: PMC5464772

Abstract Article PDF–2.3M

Select item 502109215.

Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation

Ye Jin Chai, Emma Sierecki, Vanesa M. Tomatis, Rachel S. Gormal, Nichole Giles, Isabel C. Morrow, Di Xia, Jürgen Götz, Robert G. Parton, Brett M. Collins, Yann Gambin, Frédéric A. Meunier

J Cell Biol. 2016 Sep 12; 214(6): 705–718. doi: 10.1083/jcb.201512016

PMCID:: PMC5021092

Abstract Article PDF–3.5M

Select item 477534516.

Munc18-1 and the Syntaxin-1 N-terminus Regulate Open-Closed States in a t-SNARE complex

Damian Dawidowski, David S. Cafiso

Structure. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Structure. 2016 Mar 1; 24(3): 392–400. Published online 2016 Feb 11. doi: 10.1016/j.str.2016.01.005

PMCID:: PMC4775345

Abstract Article PDF–1.5M

Select item 475803717.

TNFα induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to the plasmalemma via Munc18–1/syntaxin1/SNAP-25 mediated fusion

Jianghui Meng, Jiafu Wang, Martin Steinhoff, James Oliver Dolly

Sci Rep. 2016; 6: 21226. Published online 2016 Feb 18. doi: 10.1038/srep21226

PMCID:: PMC4758037

Abstract Article PDF–2.6M

Select item 465720618.

Label-free mass spectrometric analysis reveals complex changes in the brain proteome from the mdx-4cv mouse model of Duchenne muscular dystrophy

Sandra Murphy, Margit Zweyer, Michael Henry, Paula Meleady, Rustam R. Mundegar, Dieter Swandulla, Kay Ohlendieck

Clin Proteomics. 2015; 12: 27. Published online 2015 Nov 23. doi: 10.1186/s12014-015-9099-0

PMCID:: PMC4657206

Abstract Article PDF–2.7M

Select item 465366619.

The Q-soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (Q-SNARE) SNAP-47 Regulates Trafficking of Selected Vesicle-associated Membrane Proteins (VAMPs)

Aurelia Kuster, Sebastien Nola, Florent Dingli, Barbara Vacca, Christian Gauchy, Jean-Claude Beaujouan, Marcela Nunez, Thomas Moncion, Damarys Loew, Etienne Formstecher, Thierry Galli, Veronique Proux-Gillardeaux

J Biol Chem. 2015 Nov 20; 290(47): 28056–28069. Published online 2015 Sep 10. doi: 10.1074/jbc.M115.666362