PMC Links for GEO Profiles (Select 49114447) - PMC

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Items: 14

Select item 88065911.

PTB domain and leucine zipper motif 1 (APPL1) inhibits myocardial ischemia/hypoxia-reperfusion injury via inactivation of apoptotic protease activating factor-1 (APAF-1)/Caspase9 signaling pathway

Lina Bai, Junhua Yang, Hong Zhang, Wei Liao, Yunguang Cen

Bioengineered. 2021; 12(1): 4385–4396. Published online 2021 Jul 24. doi: 10.1080/21655979.2021.1954841

PMCID:: PMC8806591

Abstract Article PDF–2.4M

Select item 67629012.

Differential Expression of Apoptotic Protease-Activating Factor-1 and Caspase-3 Genes and Susceptibility to Apoptosis during Brain Development and after Traumatic Brain Injury

Alexander G. Yakovlev, Katsuya Ota, Geping Wang, Vilen Movsesyan, Wei-Li Bao, Koichiro Yoshihara, Alan I. Faden

J Neurosci. 2001 Oct 1; 21(19): 7439–7446. doi: 10.1523/JNEUROSCI.21-19-07439.2001

PMCID:: PMC6762901

Abstract Article PDF–247K

Select item 67260043.

Apoptosis-Inducing Factor Is a Key Factor in Neuronal Cell Death Propagated by BAX-Dependent and BAX-Independent Mechanisms

Eric C. C. Cheung, Lysanne Melanson-Drapeau, Sean P. Cregan, Jacqueline L. Vanderluit, Kerry L. Ferguson, William C. McIntosh, David S. Park, Steffany A. L. Bennett, Ruth S. Slack

J Neurosci. 2005 Feb 9; 25(6): 1324–1334. doi: 10.1523/JNEUROSCI.4261-04.2005

PMCID:: PMC6726004

Abstract Article PDF–751K

Select item 49572404.

The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identification

Ying Wang, Yang Cao, Qing Zhu, Xianfeng Gu, Yi Zhun Zhu

Sci Rep. 2016; 6: 29820. Published online 2016 Jul 22. doi: 10.1038/srep29820

PMCID:: PMC4957240

Abstract Article PDF–1.3M

Select item 42038555.

Apaf-1 Inhibitors Protect from Unwanted Cell Death in In Vivo Models of Kidney Ischemia and Chemotherapy Induced Ototoxicity

Mar Orzáez, Mónica Sancho, Sandra Marchán, Laura Mondragón, Rebeca Montava, Juan García Valero, Olatz Landeta, Gorka Basañez, Rodrigo J. Carbajo, Antonio Pineda-Lucena, Jordi Bujons, Alejandra Moure, Angel Messeguer, Carmen Lagunas, Carmen Herrero, Enrique Pérez-Payá

PLoS One. 2014; 9(10): e110979. Published online 2014 Oct 20. doi: 10.1371/journal.pone.0110979

PMCID:: PMC4203855

Abstract Article PDF–2.8M

Select item 31780596.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 31558257.

The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3

Shujun Yuan, Xinchao Yu, John M. Asara, John E. Heuser, Steven J. Ludtke, Christopher W. Akey

Structure. Author manuscript; available in PMC 2012 Aug 10.

Published in final edited form as: Structure. 2011 Aug 10; 19(8): 1084–1096. doi: 10.1016/j.str.2011.07.001

PMCID:: PMC3155825

Abstract Article PDF–2.4M

Select item 26370508.

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper

J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406

PMCID:: PMC2637050

Abstract Article

Select item 24241419.

Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats

Dario Siniscalco, Catia Giordano, Carlo Fuccio, Livio Luongo, Franca Ferraraccio, Francesca Rossi, Vito de Novellis, Kevin A. Roth, Sabatino Maione

Pharmacol Res. Author manuscript; available in PMC 2009 Mar 1.

Published in final edited form as: Pharmacol Res. 2008 Mar; 57(3): 223–233. Published online 2008 Feb 2. doi: 10.1016/j.phrs.2008.01.007

PMCID:: PMC2424141

Abstract Article PDF–1.1M

Select item 217255410.

Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis

Kevin M. Wright, Michael W. Linhoff, Patrick Ryan Potts, Mohanish Deshmukh

J Cell Biol. 2004 Oct 25; 167(2): 303–313. doi: 10.1083/jcb.200406073

PMCID:: PMC2172554

Abstract Article PDF–1.6M

Select item 129928511.

Proapoptotic BAX and BAK control multiple initiator caspases

Antonio Ruiz-Vela, Joseph T Opferman, Emily H-Y Cheng, Stanley J Korsmeyer

EMBO Rep. 2005 Apr; 6(4): 379–385. Published online 2005 Mar 18. doi: 10.1038/sj.embor.7400375

PMCID:: PMC1299285

Abstract Article PDF–175K

Select item 124231612.

Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD

Christina Berube, Louis-Martin Boucher, Weili Ma, Andrew Wakeham, Leonardo Salmena, Razqallah Hakem, Wen-Chen Yeh, Tak W. Mak, Samuel Benchimol

Proc Natl Acad Sci U S A. 2005 Oct 4; 102(40): 14314–14320. Published online 2005 Sep 23. doi: 10.1073/pnas.0506475102

PMCID:: PMC1242316

Abstract Article PDF–507K

Select item 5857413.

An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease

Hideki Mochizuki, Hideki Hayakawa, Makoto Migita, Mamoru Shibata, Ryota Tanaka, Asuka Suzuki, Yumi Shimo-Nakanishi, Takao Urabe, Masanori Yamada, Kenji Tamayose, Takashi Shimada, Masayuki Miura, Yoshikuni Mizuno

Proc Natl Acad Sci U S A. 2001 Sep 11; 98(19): 10918–10923. Published online 2001 Sep 4. doi: 10.1073/pnas.191107398