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Items: 1 to 20 of 414

1.
APC and ZBTB2 May Mediate M2 Macrophage Infiltration to Promote the Development of Renal Fibrosis: A Bioinformatics Analysis
Jianling Song, Ben Ke, Xiangdong Fang
Biomed Res Int. 2024; 2024: 5674711. Published online 2024 Sep 18. doi: 10.1155/2024/5674711
PMCID:
PMC11424844
AbstractArticlePDF–2.3M
2.
BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway
Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo
Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361
PMCID:
PMC11373599
AbstractArticlePDF–11M
3.
Proteome-scale characterisation of motif-based interactome rewiring by disease mutations
Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak, Hanna Kuss, Marcel Diallo, Emma Rask, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2024 Sep; 20(9): 1025–1048. Published online 2024 Jul 15. doi: 10.1038/s44320-024-00055-4
PMCID:
PMC11369174
AbstractArticlePDF–2.7M
4.
DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples
Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang
J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832
PMCID:
PMC11296914
AbstractArticlePDF–1.7M
5.
Plasma-Derived Extracellular Vesicles and Non-Extracellular Vesicle Components from APCMin/+ Mice Promote Pro-Tumorigenic Activities and Activate Human Colonic Fibroblasts via the NF-κB Signaling Pathway
Luis A. Arteaga-Blanco, Andrew E. Evans, Dan A. Dixon
Cells. 2024 Jul; 13(14): 1195. Published online 2024 Jul 15. doi: 10.3390/cells13141195
PMCID:
PMC11274984
AbstractArticlePDF–7.0M
6.
Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein
Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo
J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390
PMCID:
PMC11237930
AbstractArticlePDF–3.8M
7.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
8.
Bcl-2 Up-Regulation Mediates Taxane Resistance Downstream of APC Loss
Angelique R. Wise, Sara Maloney, Adam Hering, Sarah Zabala, Grace E. Richmond, Monica K. VanKlompenberg, Murlidharan T. Nair, Jenifer R. Prosperi
Int J Mol Sci. 2024 Jun; 25(12): 6745. Published online 2024 Jun 19. doi: 10.3390/ijms25126745
PMCID:
PMC11203545
AbstractArticlePDF–1.5M
9.
A nonsense mutation in exon 8 of the APC gene (Arg283Ter) causes clinically variable FAP in a Malaysian Chinese family
Zulqarnain Mohamed, Rahimah Ahmad, Ng Sau Yoke, Zubaidah Zakaria, Harun Ahmad, Tong Hung Yew
Cancer Sci. 2003 Aug; 94(8): 725–728. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01509.x
PMCID:
PMC11159997
AbstractArticlePDF–124K
10.
APC promoter hypermethylation is an early event in endometrial tumorigenesis
Atanas Ignatov, Joachim Bischoff, Tanja Ignatov, Christa Schwarzenau, Thomas Krebs, Doerthe Kuester, Serban D. Costa, Albert Roessner, Andrzej Semczuk, Regine Schneider‐Stock
Cancer Sci. 2010 Feb; 101(2): 321–327. Published online 2009 Oct 12. doi: 10.1111/j.1349-7006.2009.01397.x
PMCID:
PMC11158934
AbstractArticlePDF–317K
11.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
12.
β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53
Mohamed Bourmoum, Nikolina Radulovich, Amit Sharma, Johnny M. Tkach, Ming-Sound Tsao, Laurence Pelletier
PLoS One. 2024; 19(2): e0295030. Published online 2024 Feb 7. doi: 10.1371/journal.pone.0295030
PMCID:
PMC10849215
AbstractArticlePDF–2.1M
13.
APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation
Dan Zhang, Qi-Qi Ni, Shu-Yang Wang, Wen-Feng He, Ze-Xuan Hong, Hui-Ye Liu, Xiao-Hong Chen, Li-Jie Chen, Fang-Yi Han, Ling-Jie Zhang, Xiao-ming Li, Yan-qing Ding, Hong-li Jiao, Ya-ping Ye
Cell Mol Life Sci. 2024 Dec; 81(1): 57. Published online 2024 Jan 27. doi: 10.1007/s00018-023-05068-0
PMCID:
PMC10817841
AbstractArticlePDF–6.2M
14.
APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells
Mingjue Chen, Tetsuo Mashima, Taichi Oishi, Yukiko Muramatsu, Yosuke Seto, Manabu Takamatsu, Naomi Kawata, Shun Morino, Ayane Nakamura, Saori Inaba, Xunmei Yuan, Kohei Maruyama, Mai Suzuki, Ayana Sato, Haruka Yoshida, Myung-Kyu Jang, Anna Mizutani, Kengo Takeuchi, Kensei Yamaguchi, Fumiyuki Shirai, Satoshi Nagayama, Ryohei Katayama, Hiroyuki Seimiya
Br J Cancer. 2024 Jan 31; 130(1): 151–162. Published online 2023 Nov 15. doi: 10.1038/s41416-023-02484-8
PMCID:
PMC10782021
AbstractArticlePDF–3.4M
15.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
16.
APC ameliorates idiopathic membranous nephropathy by affecting podocyte apoptosis through the ERK1/2/YB-1/PLA2R1 axis
Ben Ke, Wen Shen, Yunfei Liao, Jing Hu, Weiping Tu, Xiangdong Fang
Mol Cell Biochem. 2023; 478(9): 1999–2011. Published online 2023 Jan 2. doi: 10.1007/s11010-022-04650-7
PMCID:
PMC10359206
AbstractArticlePDF–7.9M
17.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
18.
Let‐7b‐5p inhibits colon cancer progression by prohibiting APC ubiquitination degradation and the Wnt pathway by targeting NKD1
Yuyang Dai, Jinsong Liu, Xuyan Li, Jianzhong Deng, Cheng Zeng, Wenbin Lu, Yongzhong Hou, Ying Sheng, Honglin Wu, Qian Liu
Cancer Sci. 2023 May; 114(5): 1882–1897. Published online 2022 Dec 9. doi: 10.1111/cas.15678
Correction in:
Cancer Sci. 2023 Aug; 114(8): 3466–3469.
PMCID:
PMC10154867
AbstractArticlePDF–30M
19.
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders
Greta Pintacuda, Yu-Han H. Hsu, Kalliopi Tsafou, Ka Wan Li, Jacqueline M. Martín, Jackson Riseman, Julia C. Biagini, Joshua K.T. Ching, Daya Mena, Miguel A. Gonzalez-Lozano, Shawn B. Egri, Jake Jaffe, August B. Smit, Nadine Fornelos, Kevin C. Eggan, Kasper Lage
Cell Genom. 2023 Mar 8; 3(3): 100250. Published online 2023 Jan 24. doi: 10.1016/j.xgen.2022.100250
PMCID:
PMC10025425
AbstractArticlePDF–22M
20.
Rare Genetic Variants in Human APC Are Implicated in Mesiodens and Isolated Supernumerary Teeth
Chomchanok Panyarat, Siriruk Nakornchai, Kanoknart Chintakanon, Niramol Leelaadisorn, Worrachet Intachai, Bjorn Olsen, Sissades Tongsima, Ploy Adisornkanj, Chumpol Ngamphiw, Timothy C. Cox, Piranit Kantaputra
Int J Mol Sci. 2023 Mar; 24(5): 4255. Published online 2023 Feb 21. doi: 10.3390/ijms24054255
PMCID:
PMC10002335
AbstractArticlePDF–3.3M

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