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Items: 1 to 20 of 125

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
NER-factor DDB2 regulates HIF1α and hypoxia-response genes in HNSCC
Prashant V. Bommi, Vaibhav Chand, Nishit K. Mukhopadhyay, Pradip Raychaudhuri, Srilata Bagchi
Oncogene. Author manuscript; available in PMC 2024 May 15.
Published in final edited form as: Oncogene. 2020 Feb; 39(8): 1784–1796. Published online 2019 Nov 18. doi: 10.1038/s41388-019-1105-y
PMCID:
PMC11095046
AbstractArticlePDF–1.8M
3.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
4.
Brazilian XP-E siblings carrying a novel DDB2 variant developed early-onset melanoma: a case report
Ana Rafaela de Souza Timoteo, Isabel Cristina Pinheiro de Almeida, Andrey A Yurchenko, Sheila Ramos de Miranda Henriques, Paulo de Souza Segundo, Fatemeh Rajabi, Sergey Nikolaev, Tirzah Braz Petta
BMC Med Genomics. 2023; 16: 186. Published online 2023 Aug 12. doi: 10.1186/s12920-023-01622-8
PMCID:
PMC10422713
AbstractArticlePDF–1.6M
5.
The Role of Alternative Splicing Factors, DDB2-Related Ageing and DNA Damage Repair in the Progression and Prognosis of Stomach Adenocarcinoma Patients
Xinshu Wang, Zhiyuan Huang, Lei Li, Yuntong Yang, Jiyuan Zhang, Li Wang, Jian Yuan, Yunhui Li
Genes (Basel) 2023 Jan; 14(1): 39. Published online 2022 Dec 23. doi: 10.3390/genes14010039
PMCID:
PMC9858704
AbstractArticlePDF–2.8M
6.
Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex
Elizaveta T. Wick, Colton J. Treadway, Zhijun Li, Nathan I. Nicely, Zhizhong Ren, Albert S. Baldwin, Yue Xiong, Joseph S. Harrison, Nicholas G. Brown
J Virol. 2022 Sep; 96(17): e00826-22. Published online 2022 Aug 8. doi: 10.1128/jvi.00826-22
PMCID:
PMC9472758
AbstractArticlePDF–3.2M
7.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
8.
Hypoxia-inducible CircPFKFB4 Promotes Breast Cancer Progression by Facilitating the CRL4DDB2 E3 Ubiquitin Ligase-mediated p27 Degradation
Hang Chen, Rui Yang, Lei Xing, Bin Wang, Dawei Liu, Xiaoqiang Ou, Yumei Deng, Rong Jiang, Junxia Chen
Int J Biol Sci. 2022; 18(9): 3888–3907. Published online 2022 Jun 6. doi: 10.7150/ijbs.72842
PMCID:
PMC9254479
AbstractArticlePDF–5.0M
9.
Gentiopicroside targets PAQR3 to activate the PI3K/AKT signaling pathway and ameliorate disordered glucose and lipid metabolism
Haiming Xiao, Xiaohong Sun, Zeyuan Lin, Yan Yang, Meng Zhang, Zhanchi Xu, Peiqing Liu, Zhongqiu Liu, Heqing Huang
Acta Pharm Sin B. 2022 Jun; 12(6): 2887–2904. Published online 2022 Jan 6. doi: 10.1016/j.apsb.2021.12.023
PMCID:
PMC9214054
AbstractArticlePDF–8.5M
10.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
11.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
12.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
13.
Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins
Namrata Kumar, Arjan F. Theil, Vera Roginskaya, Yasmin Ali, Michael Calderon, Simon C. Watkins, Ryan P. Barnes, Patricia L. Opresko, Alex Pines, Hannes Lans, Wim Vermeulen, Bennett Van Houten
Nat Commun. 2022; 13: 974. Published online 2022 Feb 21. doi: 10.1038/s41467-022-28642-9
PMCID:
PMC8861037
AbstractArticlePDF–6.2M
14.
Proteomic Analysis of Nuclear Hepatitis B Virus Relaxed Circular DNA-Associated Proteins Identifies UV-Damaged DNA Binding Protein as a Host Factor Involved in Covalently Closed Circular DNA Formation
Alexander L. Marchetti, Hu Zhang, Elena S. Kim, Xiaoyang Yu, Sunbok Jang, Mu Wang, Haitao Guo
J Virol. 2022 Jan; 96(2): e01360-21. Prepublished online 2021 Oct 27. Published online 2022 Jan 26. doi: 10.1128/JVI.01360-21
PMCID:
PMC8791301
AbstractArticlePDF–3.0M
15.
MEKK1-Dependent Activation of the CRL4 Complex Is Important for DNA Damage-Induced Degradation of p21 and DDB2 and Cell Survival
Susanne Bacher, Hilda Stekman, Carla M. Farah, Annika Karger, Michael Kracht, M. Lienhard Schmitz
Mol Cell Biol. 2021 Oct; 41(10): e00081-21. Prepublished online 2021 Jul 12. Published online 2021 Sep 24. doi: 10.1128/MCB.00081-21
PMCID:
PMC8462458
AbstractArticlePDF–3.1M
16.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
17.
USP44 Stabilizes DDB2 to Facilitate Nucleotide Excision Repair and Prevent Tumors
Ying Zhang, Imke K. Mandemaker, Syota Matsumoto, Oded Foreman, Christopher P. Holland, Whitney R. Lloyd, Kaoru Sugasawa, Wim Vermeulen, Jurgen A. Marteijn, Paul J. Galardy
Front Cell Dev Biol. 2021; 9: 663411. Published online 2021 Apr 16. doi: 10.3389/fcell.2021.663411
PMCID:
PMC8085418
AbstractArticlePDF–1.5M
18.
Expanding molecular roles of UV-DDB: shining light on genome stability and cancer
Maria Beecher, Namrata Kumar, Sunbok Jang, Vesna Rapić-Otrin, Bennett Van Houten
DNA Repair (Amst) Author manuscript; available in PMC 2021 Oct 1.
Published in final edited form as: DNA Repair (Amst). 2020 Oct; 94: 102860. Published online 2020 Apr 27. doi: 10.1016/j.dnarep.2020.102860
PMCID:
PMC7873659
AbstractArticlePDF–1.7M
19.
DDB2 regulates DNA replication through PCNA-independent degradation of CDT2
Xiaojun Wu, Min Yu, Zhuxia Zhang, Feng Leng, Yue Ma, Ni Xie, Fei Lu
Cell Biosci. 2021; 11: 34. Published online 2021 Feb 8. doi: 10.1186/s13578-021-00540-5
PMCID:
PMC7869461
AbstractArticlePDF–2.7M
20.
Functional impacts of the ubiquitin–proteasome system on DNA damage recognition in global genome nucleotide excision repair
Wataru Sakai, Mayumi Yuasa-Sunagawa, Masayuki Kusakabe, Aiko Kishimoto, Takeshi Matsui, Yuki Kaneko, Jun-ichi Akagi, Nicolas Huyghe, Masae Ikura, Tsuyoshi Ikura, Fumio Hanaoka, Masayuki Yokoi, Kaoru Sugasawa
Sci Rep. 2020; 10: 19704. Published online 2020 Nov 12. doi: 10.1038/s41598-020-76898-2
PMCID:
PMC7665181
AbstractArticlePDF–2.1M

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