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Select item 107028401.

Lipin‐2 regulates the antiviral and anti‐inflammatory responses to interferon

Nagore de Pablo, Clara Meana, Javier Martínez‐García, Pablo Martínez‐Vicente, Manuel Albert, Susana Guerra, Ana Angulo, Jesús Balsinde, María A Balboa

EMBO Rep. 2023 Dec; 24(12): e57238. Published online 2023 Nov 6. doi: 10.15252/embr.202357238

PMCID:: PMC10702840

Abstract Article PDF–2.2M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 91197363.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 82524564.

Novel Majeed Syndrome–Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis

Farzana Bhuyan, Adriana A. de Jesus, Jacob Mitchell, Evgenia Leikina, Rachel VanTries, Ronit Herzog, Karen B. Onel, Andrew Oler, Gina A. Montealegre Sanchez, Kim A. Johnson, Lena Bichell, Bernadette Marrero, Luis Fernandez De Castro, Yan Huang, Katherine R. Calvo, Michael T. Collins, Sundar Ganesan, Leonid V. Chernomordik, Polly J. Ferguson, Raphaela Goldbach‐Mansky

Arthritis Rheumatol. 2021 Jun; 73(6): 1021–1032. Published online 2021 May 9. doi: 10.1002/art.41624

PMCID:: PMC8252456

Abstract Article PDF–1.0M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78906206.

Identification of lipidomic profiles associated with drug-resistant prostate cancer cells

Lishann M. Ingram, Morgan C. Finnerty, Maryam Mansoura, Chau-Wen Chou, Brian S. Cummings

Lipids Health Dis. 2021; 20: 15. Published online 2021 Feb 17. doi: 10.1186/s12944-021-01437-5

PMCID:: PMC7890620

Abstract Article PDF–2.8M

Select item 74273277.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 71151288.

Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan

Chen Khuan Wong, Arthur William Lambert, Sait Ozturk, Panagiotis Papageorgis, Delia Lopez, Ning Shen, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Hui Feng, Sam Thiagalingam

Mol Cancer Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 414–423. Published online 2020 Jan 13. doi: 10.1158/1541-7786.MCR-19-0525

PMCID:: PMC7115128

Abstract Article PDF–1.6M

Select item 69127359.

Differential Roles of Lipin1 and Lipin2 in the Hepatitis C Virus Replication Cycle

Victoria Castro, Gema Calvo, Ginés Ávila-Pérez, Marlène Dreux, Pablo Gastaminza

Cells. 2019 Nov; 8(11): 1456. Published online 2019 Nov 18. doi: 10.3390/cells8111456

PMCID:: PMC6912735

Abstract Article PDF–4.0M

Select item 582692610.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 429537512.

Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase

Tai Young Kim, Priscila F. Siesser, Kent L. Rossman, Dennis Goldfarb, Kathryn Mackinnon, Feng Yan, XianHua Yi, Michael J. MacCoss, Randall T. Moon, Channing J. Der, Michael B. Major

Mol Cell Biol. 2015 Jan; 35(1): 167–181. Prepublished online 2014 Oct 20. Published online 2014 Dec 9. doi: 10.1128/MCB.00857-14

PMCID:: PMC4295375

Abstract Article PDF–5.6M

Select item 390955313.

Chromosomal structural variations during progression of a prostate epithelial cell line to a malignant metastatic state inactivate the NF2, NIPSNAP1, UGT2B17, and LPIN2 genes

Ankit Malhotra, Yoshiyuki Shibata, Ira M Hall, Anindya Dutta

Cancer Biol Ther. 2013 Sep 1; 14(9): 840–852. Published online 2013 Jul 26. doi: 10.4161/cbt.25329

PMCID:: PMC3909553

Abstract Article PDF–3.0M

Select item 385466914.

Genome Wide Association Study (GWAS) of Chagas Cardiomyopathy in Trypanosoma cruzi Seropositive Subjects

Xutao Deng, Ester C. Sabino, Edecio Cunha-Neto, Antonio L. Ribeiro, Barbara Ianni, Charles Mady, Michael P. Busch, Mark Seielstad, the REDSII Chagas study group from the NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component

PLoS One. 2013; 8(11): e79629. Published online 2013 Nov 20. doi: 10.1371/journal.pone.0079629

PMCID:: PMC3854669

Abstract Article PDF–408K

Select item 366014715.

Efficacy of anti-IL-1 treatment in Majeed syndrome

Troels Herlin, Bente Fiirgaard, Mette Bjerre, Gitte Kerndrup, Henrik Hasle, Xinyu Bing, Polly J. Ferguson

Ann Rheum Dis. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Ann Rheum Dis. 2013 Mar; 72(3): 410–413. Published online 2012 Oct 20. doi: 10.1136/annrheumdis-2012-201818

PMCID:: PMC3660147

Abstract Article PDF–1.2M

Select item 360893016.

Genome-wide association study of body mass index in 23,000 individuals with and without asthma

Erik Melén, Raquel Granell, Manolis Kogevinas, David Strachan, Juan R. Gonzalez, Matthias Wjst, Debbie Jarvis, Markus Ege, Charlotte Braun-Fahrländer, Jon Genuneit, Elisabeth Horak, Emmanuelle Bouzigon, Florence Demenais, Francine Kauffmann, Valérie Siroux, Sven Michel, Andrea von Berg, Andrea Heinzmann, Michael Kabesch, Nicole M. Probst-Hensch, Ivan Curjuric, Medea Imboden, Thierry Rochat, John Henderson, Jonathan A.C. Sterne, Wendy L. McArdle, Jennie Hui, Alan L. James, A. William Musk, Lyle J. Palmer, Allan Becker, Anita L. Kozyrskyj, Moira Chan-Young, Julie E. Park, Andy Leung, Denise Daley, Maxim B. Freidin, Ivan A. Deev, Ludmila M. Ogorodova, Valery P. Puzyrev, Juan C. Celedón, John M. Brehm, Michelle M. Cloutier, Glorisa Canino, Edna Acosta-Pérez, Manuel Soto-Quiros, Lydiana Avila, Anna Bergström, Jessica Magnusson, Cilla Söderhäll, Inger Kull, Salome Scholtens, H. Marike Boezen, Gerard H. Koppelman, Alet H. Wijga, Ingo Marenholz, Jorge Esparza-Gordillo, Susanne Lau, Young-Ae Lee, Marie Standl, Carla M. T. Tiesler, Claudia Flexeder, Joachim Heinrich, Rachel A. Myers, Carole Ober, Dan L. Nicolae, Martin Farrall, Ashish Kumar, Miriam F. Moffatt, William O.C.M. Cookson, Jessica Lasky-Su

Clin Exp Allergy. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Clin Exp Allergy. 2013 Apr; 43(4): 463–474. doi: 10.1111/cea.12054