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Select item 109332671.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 108946692.

Elongation of very long chain fatty acids-3 (Elovl3) is activated by ZHX2 and is a regulator of cell cycle progression

Kate Townsend Creasy, Hui Ren, Jieyun Jiang, Martha L. Peterson, Brett T. Spear

Am J Physiol Gastrointest Liver Physiol. 2023 Dec 1; 325(6): G582–G592. Published online 2023 Oct 17. doi: 10.1152/ajpgi.00235.2022

PMCID:: PMC10894669

Abstract Article

Select item 105658763.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104828624.

Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response

Siyu Tan, Zehua Wang, Na Li, Xiaowei Guo, Yankun Zhang, Hongxin Ma, Xueqi Peng, Ying Zhao, Chunyang Li, Lifen Gao, Tao Li, Xiaohong Liang, Chunhong Ma

Cell Death Differ. 2023 Sep; 30(9): 2104–2119. Published online 2023 Aug 15. doi: 10.1038/s41418-023-01202-4

PMCID:: PMC10482862

Abstract Article PDF–7.2M

Select item 94572485.

USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer

Haibiao Xie, Jin Zhou, Xijuan Liu, Yawei Xu, Austin J. Hepperla, Jeremy M. Simon, Tao Wang, Hongwei Yao, Chengheng Liao, Albert S. Baldwin, Kan Gong, Qing Zhang

Proc Natl Acad Sci U S A. 2022 Sep 6; 119(36): e2119854119. Published online 2022 Aug 29. doi: 10.1073/pnas.2119854119

PMCID:: PMC9457248

Abstract Article PDF–3.1M

Select item 93920636.

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling

Yansheng Zhai, Xiaoyan Huang, Keren Zhang, Yuchen Huang, Yanlong Jiang, Jingwei Cui, Zhe Zhang, Cookson K. C. Chiu, Weiye Zhong, Gang Li

Nat Commun. 2022; 13: 4906. Published online 2022 Aug 20. doi: 10.1038/s41467-022-32689-z

PMCID:: PMC9392063

Abstract Article PDF–2.0M

Select item 91197367.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 88288958.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 86024519.

Identification of proximal SUMO-dependent interactors using SUMO-ID

Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland

Nat Commun. 2021; 12: 6671. Published online 2021 Nov 18. doi: 10.1038/s41467-021-26807-6

PMCID:: PMC8602451

Abstract Article PDF–11M

Select item 829213210.

Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity

Siyu Tan, Xiaowei Guo, Mengzhen Li, Tixiao Wang, Zehua Wang, Chunyang Li, Zhuanchang Wu, Nailin Li, Lifen Gao, Xiaohong Liang, Chunhong Ma

J Exp Med. 2021 Sep 6; 218(9): e20210009. Published online 2021 Jul 19. doi: 10.1084/jem.20210009

PMCID:: PMC8292132

Abstract Article PDF–7.0M

Select item 816787711.

Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer

Anqi Cheng, Xiong Guo, Xinglong Dai, Ziwei Wang

FEBS Open Bio. 2021 Jun; 11(6): 1785–1798. Published online 2021 May 24. doi: 10.1002/2211-5463.13160

PMCID:: PMC8167877

Abstract Article PDF–9.3M

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 810809313.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 786227914.

HNRNPD interacts with ZHX2 regulating the vasculogenic mimicry formation of glioma cells via linc00707/miR-651-3p/SP2 axis

Sifei Yu, Xuelei Ruan, Xiaobai Liu, Fangfang Zhang, Di Wang, Yunhui Liu, Chunqing Yang, Lianqi Shao, Qianshuo Liu, Lu Zhu, Yang Lin, Yixue Xue

Cell Death Dis. 2021 Feb; 12(2): 153. Published online 2021 Feb 4. doi: 10.1038/s41419-021-03432-1

PMCID:: PMC7862279

Abstract Article PDF–5.7M

Select item 739436515.

The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases

Camille Macé, Maria Del Nogal Avila, Caroline B. Marshall, Joubert Kharlyngdoh, Ranjan Das, Eduardo Molina-Jijon, Hector Donoro Blazquez, Suresh Shastry, Elisabeth Soria, Jack Wetzels, Henry Dijkman, Carmen Avila-Casado, Lionel C. Clement, Sumant S. Chugh

Kidney Int. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Kidney Int. 2020 Apr; 97(4): 753–764. Published online 2019 Nov 26. doi: 10.1016/j.kint.2019.11.011

PMCID:: PMC7394365

Abstract Article PDF–2.3M

Select item 720607216.

Tumor suppressor ZHX2 inhibits NAFLD–HCC progression via blocking LPL-mediated lipid uptake

Zhuanchang Wu, Hongxin Ma, Liyuan Wang, Xiaojia Song, Jie Zhang, Wen Liu, Yutong Ge, Yang Sun, Xiangguo Yu, Zehua Wang, Jianping Wang, Yankun Zhang, Chunyang Li, Nailin Li, Lifen Gao, Xiaohong Liang, Xuetian Yue, Chunhong Ma

Cell Death Differ. 2020 May; 27(5): 1693–1708. Published online 2019 Nov 18. doi: 10.1038/s41418-019-0453-z

PMCID:: PMC7206072

Abstract Article PDF–6.2M

Select item 720601017.

ZHX2 drives cell growth and migration via activating MEK/ERK signal and induces Sunitinib resistance by regulating the autophagy in clear cell Renal Cell Carcinoma

Liangsong Zhu, Rong Ding, Hao Yan, Jin Zhang, Zongming Lin

Cell Death Dis. 2020 May; 11(5): 337. Published online 2020 May 7. doi: 10.1038/s41419-020-2541-x

Correction in:: Cell Death Dis. 2021 Apr; 12(4): 399.

PMCID:: PMC7206010

Abstract Article PDF–4.7M

Select item 704718418.

ZHX2 restricts hepatocellular carcinoma by suppressing stem cell-like traits through KDM2A-mediated H3K36 demethylation

Qinghai Lin, Zhuanchang Wu, Xuetian Yue, Xiangguo Yu, Zehua Wang, Xiaojia Song, Leiqi Xu, Ying He, Yutong Ge, Siyu Tan, Tixiao Wang, Hui Song, Detian Yuan, Yaoqin Gong, Lifen Gao, Xiaohong Liang, Chunhong Ma

EBioMedicine. 2020 Mar; 53: 102676. Published online 2020 Feb 27. doi: 10.1016/j.ebiom.2020.102676

PMCID:: PMC7047184

Abstract Article PDF–7.0M

Select item 674682219.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

Select item 616668220.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

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